• Title/Summary/Keyword: CC1₄

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공통평가기준 v2.3과 v3.1 비교 분석

  • 조혜숙;전웅렬;정한재;이성진;유연정;김승주;원동호
    • 정보보호학회지
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    • 제17권6호
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    • pp.9-19
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    • 2007
  • 미국, 독일 등 선진국을 중심으로 개발된 공통평가기준(Common Criteria, CC) 3.1이 공식 문서로 등재되어 2009년 9월부터는 기존의 CC v2.3을 완전히 대체할 것으로 예상됨에 따라 현재 우리나라 평가 완료된 CC v2.3 기반 보호프로파일은 CC 3.1 기반 보호프로파일로 개정이 필요하다. 따라서 본 논문은 CC v2.3과 v3.1에서의 보호프로파일 요구사항을 비교 및 분석하고, 보안기능 및 보증요구사항의 평가업무량 및 제출물 작성수준을 분석한다. 이러한 미국, 영국, 캐나다, 프랑스, 네덜란드 등 선진국의 주도하에 개발되고 있는 CC v3.1에 대한 분석을 통하여 국제적으로 새롭게 정립되고 있는 평가기준 및 평가방법에 대한 기술을 확보할 수 있으며, 향후 CC v3.1에 의한 평가 기반을 마련하는데 기여 할 것이다.

Comparison of Total Protein, DNA, and RNA Contents by Corpus Luteum in Various Stages of Estrous Cycle and Pregnancy

  • K. S. Baek;Kim, Y. S.;Lee, C. N.
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2001년도 춘계학술발표대회
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    • pp.79-79
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    • 2001
  • This study was conducted to measure the total protein, DNA, and RNA contents of corpus luteum(CL) in various stages of estrous cycle and pregnancy. CLs were collected from a local slaughterhouse and stages of the estrous cycle of CL were classified as CL1~2, days 1 to 10; CL3(with/without central cavity), days 11 to 17; CL4, days 18 to 20 by method of Ireland et. al(1980) and stages of the pregnancy of CL were classified as P1~3, months 11~3: P4~6, months 4~6; P7~9, months 7~9 of pregnancy. CL3 with/without central cavity(CC) was identified as described by Kastelic et. al.(1990)-CL with CC, more than 2mm in diameter; CL without CC, less than 2mm in diameter. In total protein content, CL3 with CC was significantly lower than P7~9(p<.05). The total DNA content was lower in CL3 with CC than CL3 without CC and CL4(p<.05). In protein : DNA ratio, CL3 with CC was significantly lower than CL4(p<.05), CL3 without CC was significantly lower than P7~9(p<.05), CL4 was significantly lower than CL3 with CC, P1~3 and P7~9(p<.05). No differences were observed in RNA content, protein:RNA ratio, RNA/DNA of CLs in stages of estrous cycle and pregnancy.

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No Association of the TGF-β1 29T/C Polymorphism with Breast Cancer Risk in Caucasian and Asian Populations: Evidence from a Meta-Analysis Involving 55, 841 Subjects

  • Alqumber, Mohammed A.A.;Dar, Sajad Ahmad;Haque, Shafiul;Wahid, Mohd;Singh, Rohit;Akhter, Naseem
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권20호
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    • pp.8725-8734
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    • 2014
  • The transforming growth factor-${\beta}1$ (TGF-${\beta}1$) gene 29 T/C polymorphism is thought to be associated with breast cancer risk. However, reports are largely conflicting and underpowered. We therefore conducted a meta-analysis of all available case-control studies relating the TGF-${\beta}1$ 29T/C polymorphism to the risk of developing breast cancer by including a total of 31 articles involving 24,021 cases and 31,820 controls. Pooled ORs were generated for the allele contrasts, with additive genetic, dominant genetic and recessive genetic models. Subgroup analysis was also performed by ethnicity for the TGF-${\beta}1$ 29T/C polymorphism. No association was found in the overall analysis (C vs T: OR=1.028, 95% CI=0.949-1.114, p-value 0.500; CC vs TC: OR= 1.022, 95% CI=0.963-1.085, p-value 0.478; CC vs TT: OR= 1.054, 95% CI=0.898-1.236, p-value 0.522; CC vs TT+ TC: OR= 1.031, 95% CI=0.946-1.124, p-value 0.482; TT vs CC+TC: OR= 0.945, 95% CI=0.827-1.080, p-value 0.403). Similarly, in the subgroup analysis by ethnicity, no association was found in Caucasian (C vs T: OR= 1.041, 95% CI=0.932-1.162, p-value 0.475; CC vs TC: OR= 1.031, 95% CI=0.951-1.118, p-value 0.464; CC vs TT: OR= 1.081, 95% CI=0.865-1.351, p-value 0.493; CC vs TT+TC: OR= 1.047, 95% CI=0.929-1.180, p-value 0.453; TT vs CC+TC: OR= 0.929, 95% CI=0.775-1.114, p-value 0.429;) and Asian populations (C vs T: OR= 1.004, 95% CI=0.908-1.111, p-value 0.931; CC vs TC: OR= 0.991, 95% CI=0.896-1.097, p-value 0.865; CC vs TT: OR= 1.015, 95% CI=0.848-1.214, p-value 0.871; CC vs TT+TC: OR= 1.000, 95% CI=0.909-1.101, p-value 0.994; TT vs CC+TC: OR= 0.967, 95% CI=0.808-1.159, p-value 0.720;). No evidence of publication bias was detected during the analysis. No significant association with breast cancer risk was demonstrated overall or on subgroup (Caucasian and Asian) analysis. It can be concluded that TGF-${\beta}1$ 29T/C polymorphism does not play a role in breast cancer susceptibility in overall or ethnicity-specific manner.

계지(桂枝)에서 정제한 보체계 활성화 다당의 작용양식과 당쇄구조 (Activation Mode and Glycosidic Linkage of Anti-Complementary Polysaccharide Isolated from Young Stems of Cinnamomum cassia Blume)

  • 나경수;안현정;권미향
    • 한국식품영양과학회지
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    • 제26권2호
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    • pp.248-253
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    • 1997
  • 계지에서 분리한 보체계 활성화 다당의 보체 활성화양식과 다당의 당쇄결합에 관하여 검토하였다. 계지 보체계 활성화 다당획분들(CC-IIIa, CC-IIIb, CC-IIIc)들은 정상인의 혈청중에 존재하는 주요 보체성분인 C3를 활성화하여 C3a와 C3b 보체 산물을 생성 시켰는데 이 과정은 anti-human C3를 이용한 면역전기영동을 실시하여 확인하였다. $Ca^{++}$ 유무시의 보체계 활성을 측정한 결과 계지에서 분리된 CC-IIIa-3는 고전적 경로(classical pathway)와 부경로(alternative pathway)를 동시에 활성화시킴을 확인하였다. CC-IIIa-3을 메틸화하여 GC/MS로 분석한 결과 비환원 말단의 galactopyranose와 glucopyranose가 확인되었고 1,2-linked rhamnopyranose, 1,6-linked mannopyranose, 1,3-linked glucopyranose, 1,6-linked galactopyranose 등이 확인되었다.

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비천공 Breathable필름이 몇 가지 저장온도에서 '후지' 사과의 MA 저장성에 미치는 영향 (Effect of Non-Perforated Breathable Films on the Storability of 'Fuji' Apples in Modified Atmosphere Condition in the Different Storage Temperature)

  • 최인이;홍성미;정민재;백준필;강호민
    • 생물환경조절학회지
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    • 제23권1호
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    • pp.60-64
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    • 2014
  • '후지' 사과의 MA 저장성 향상을 위해 저장 온도별로 적합한 비천공 breathable 필름 종류를 구명하고자 본 연구를 수행하였다. 저장중 생체중 감소율은 모든 저장온도의 비천공 breathable 필름 처리구에서 저장 최종일까지 약 2.0% 이하를 나타냈다. 포장내 대기조성으로 볼 때 $1^{\circ}C$에서 1,300cc 필름, $8^{\circ}C$에서 5,000cc 필름, 그리고 $20^{\circ}C$에서 10,000cc 필름이 최적 MA 조건에 가장 근접하였다. 저장 중 포장내 에틸렌 농도는 모든 저장온도에서 산소 투과도가 가장 높았던 40,000cc 필름 처리구가 낮게 유지되었다. 저장 최종일의 $1^{\circ}C$ 1,300cc 필름이 당도, 비타민 C 함량, 그리고 외관 품질이 우수하였고, $8^{\circ}C$ 5,000cc 필름이 당도와 이취 정도가 양호하였으며, 그리고 $20^{\circ}C$ 10,000cc 필름이 경도와 외관상 품질이 높은 수치를 나타내었다. 이상의 결과로 포장내 대기조성과 과실의 내외적 품질을 비교한 결과 '후지' 사과의 MA 저장시 $1^{\circ}C$는 1,300cc 필름, $8^{\circ}C$는 5,000cc 필름, 그리고 $20^{\circ}C$에서는 10,000cc 필름이 적합하다고 판단된다.

석면방직업 근로자의 석면노출 실태와 과거농도 추정에 관한 연구 (A Study on Exposure Among Asbestos Textile Workers and Estimation of their Historical Exposures)

  • 박정임;윤충식;백남원
    • 한국산업보건학회지
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    • 제5권1호
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    • pp.16-39
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    • 1995
  • From July 8 to September 2 1994, asbestos exposure level among asbestos textile workers was surveyed. Six plants out of plants in Korea were selected for this study. In addition to the exposure level, the relationship between the level of exposure and some factors affecting exposure were studied. Also, using historical data of asbestos concentrations in asbestos textile plants plus current data, trend of asbestos exposure level could be introduced. Historical exposure level was estimated on the basis of these data. The main results of this study are follows. 1. Average concentration of all six plants surveyed was 1.54 f/cc, and range of those concentrations was 0.03 - 11.58 f/cc. The minimum average concentration was 0.32 f/cc and the maximum was 8.04 f/cc which is four times higher than the Korean standard. A wide difference of exposure level among the workers of different plants was observed. In three plants, the half of all the plants surveyed, their average concentrations exceeded the Korean standard, and those in all the plants exceeded the ACGIH TLV. 2. Among total 56 samples, 22 samples(39%) were in excess of the Korean standard, and 53 samples(95%) were above the ACGIH TLV. Among 32 personal samples, 15 samples(47%) exceeded the Korean standard, and 30 samples(94%) exceeded the ACGIH TLV. Among 24 area samples excluding a few samples collected in office area, seven samples exceeded the Korean standard, and 23 samples( 96%) exceeded the ACGIH TLV. 3. Distributions of concentrations were observed by processes. In weaving, the highest, average concentration was 4.29 f/cc, and range was 2.61 - 11.58 f/cc. In spinning, average concentration was 2.22 f/cc, and range was 0.41 - 8.93 f/cc. In carding, average concentration was 1.98 f/cc, and range was 0.23 - 10.93 f/cc, In twisting, average concentration was 1.65 f/cc, and range was 0.21 - 9.83 f/cc. In mixing, the lowest, average concentration was 0.48 f/cc, and range was 0.22 - 1.20 f/cc. 4. All the samples from basic processes of asbestos textile plants were above the ACGIH TLV. Nineteen samples(45%) out of all these 42 samples exceeded Korean standard. Fourteen samples(58%) of total 24 personal samples, and five samples(28%) of total 18 area samples exceeded the Korean standard. Considering processes, all the samples in weaving process exceeded the Korean standard and 50 did 54% of those in spinning, 40% in carding, and 27% in twisting. 5. Trend of decreasing asbestos concentrations in asbestos textile plants was observed by time. 6. Asbestos concentrations in asbestos textile plant in 1975 were estimated to be 11.0 - 92.4 f/cc.

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공통평가기준(CC) 버전 3.0 분석 (Analysis on Common Criteria Improvements in Version 3.0)

  • 노병규;김영태;박두순;김점구
    • 융합보안논문지
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    • 제5권4호
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    • pp.7-18
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    • 2005
  • 현재, ISO/IEC SC27 WG3에서는 공통평가기준 개발위원회(CCDB)를 주축으로 CE V3.0의 개정작업을 2008년까지 국제표준을 목표로 적극적으로 진행하고 있다. 따라서 CC V3.0의 변경내용을 분석하여 국가적 차원에서 CC V2.*에서 V3.0의 변화에 철저하게 대비할 필요가 있다. 이에 따라 본 논문에서는 현재 개정 중인 CC V3.0의 개선내용을 CC V3.0 개용내용 요약, 제1부-소개 및 일반모델 개정내용, 제2부-보안기능컴포넌트의 개정내용, 제3부-보안보증컴포넌트의 개정내용 등 크게 네 개의 영역으로 나누어 정밀분석하고 CC V3.0의 개선사항 및 변경내용에 대해 상세하게 설명한다.

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A Second Thioltransferase from Chinese Cabbage: Purification and Characterization

  • Cho, Young-Wook;Park, Eun-Hee;Lim, Chang-Jin
    • BMB Reports
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    • 제32권2호
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    • pp.133-139
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    • 1999
  • Thioltransferase, also known as glutaredoxin, was previously purified and characterized from Chinese cabbage (Brassica campestris ssp. napus var. pekinensis). However, in the process of gel filtration on Sephadex G-75, there were two activity peaks. In this study, a second thioltransferase (TTase CC-2) in the minor peak of the Sephadex G-75 elution profile was further purified using affinity chromatography on an S-hexylglutathione-agarose column by eluting with buffer solution containing 2.5 mM S-hexylglutathione. It showed a single band on SDS-PAGE indicating that TTase CC-2 is electrophoretically homogeneous. The molecular weight of TTase CC-2 was estimated to be about 22,000 daltons, and its isoelectric point was determined to be 6.73. Its size appears to be atypical and much larger than that of the first thioltransferase (TTase CC-1) from Chinese cabbage, and it can utilize 2-hydroxyethyl disulfide, S-sulfocysteine, and insulin as substrates. S-sulfocysteine was found to be a superior substrate for TTase CC-2. TTase CC-2 also displayed the reducing activity for non-disulfides such as dehydroascorbic acid. Its optimum pH was 8.5, which was consistent with that of TTase CC-1. TTase CC-2 activity was greatly activated by L-cysteine and reduced glutathione, and was found to be less heat-stable compared with TTase CC-1. Molecular and physiological differences between TTase CC-1 and TTase CC-2 remain to be elucidated. Chinese cabbage is the first plant which is known to contain two kinds of thioltransferases.

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합성형 정보보호제품 평가를 위한 취약성 분석 방법 개발에 관한 연구 (A Study on Vulnerability Analysis Methodology for Composite Security Product Evaluation)

  • 김석수;송재구
    • 융합보안논문지
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    • 제8권3호
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    • pp.19-24
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    • 2008
  • 침입차단 시스템, 침입탐지 시스템 등 정보보호제품이 얼마나 안전하게 개발되고 구현되었는지 검증하기 위한 방안으로 공통평가기준(CC)를 제정 하여 제품을 평가한다. 이에 기존까지 적용된 CC v2.3에서 버전이 3.1로 전환이 되며 가장 큰 차이점인 정보보호 제품에 대한 평가방법론을 사전 확보하여 버전 3.1 수용 준비가 요구되고 있다. 이에 본 연구에서는 CC v3기반 합성제품 시험 및 취약성 분석 방법에 대한 연구를 진행하였다. 특히 합성형 정보보호제품 시험방법론을 기존원칙과 세부 방법론으로 분류하여 구체적 방안을 제시하고자 한다.

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CC기반에서 보증수준 및 제품유형을 동시에 고려한 평가업무량 모델 (An assurance level and product type based evaluation effort model for CC evaluation)

  • 최상수;최승;이완석;이강수
    • 정보보호학회논문지
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    • 제14권1호
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    • pp.25-34
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    • 2004
  • CC(=ISO/IEC 15408)는 정보보호시스템의 국제표준이며 CC평가 및 인증체계에서는 평가기관 운영하며 평가기관에서는 적정한 평가비 산정을 위한 근거가 필요하다. 본 논문에서는 특정한 평가기관의 환경이 아니라, CC기준과 기존의 PP 및 ST만을 바탕으로 하여, 제품유형별 및 보증수준별 평가업무량 모델을 제시하였으며, 평가실무자득의 경험, 보안기능의 사용율 개념 및 기능점수방법 등을 이용하였다. 본 결과는 CC평가환경에서 정보보호제품의 평가비 및 기간의 산정을 위한 기본자료로 활용될 수 있을 것이다.