• Nuclear Engineering and Technology
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• v.50 no.8
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• pp.1426-1432
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• 2018

This paper presents a neutron detector configuration using EJ-301 scintillation liquid, a R9420 photo-multiplier and a homemade preamplifier. The detector qualities which include the energy linearity, efficiency response and neutron/gamma discrimination are guaranteed for neutron detection in the energy range from 0 to 3000 keVee. Regarding the neutron/gamma discrimination capability, four pulse shape discrimination (PSD) methods which are the threshold crossing time (TCT), pulse gradient analysis (PGA), charge comparison (CC) and correlation pattern recognition (CPR), were evaluated and discussed; among of these, the CPR method provides the best neutron/gamma discrimination.

• Computers and Concrete
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• v.32 no.6
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• pp.607-613
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• 2023

The objective of this work is to determine the compressive strength of geopolymer concrete utilizing four distinct machine learning approaches. These techniques are known as gradient boosting machine (GBM), generalized linear model (GLM), extremely randomized trees (XRT), and deep learning (DL). Experimentation is performed to collect the data that is then utilized for training the models. Compressive strength is the response variable, whereas curing days, curing temperature, silica fume, and nanosilica concentration are the different input parameters that are taken into consideration. Several kinds of errors, including root mean square error (RMSE), coefficient of correlation (CC), variance account for (VAF), RMSE to observation's standard deviation ratio (RSR), and Nash-Sutcliffe effectiveness (NSE), were computed to determine the effectiveness of each algorithm. It was observed that, among all the models that were investigated, the GBM is the surrogate model that can predict the compressive strength of the geopolymer concrete with the highest degree of precision.

• Journal of The Korean Society of Grassland and Forage Science
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• v.15 no.1
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• pp.30-36
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• 1995

Pasture composed of about 30% botanical composition of white clover (Trijolium repem L.) is desirable in its productivity and quality. To get information on maintaining its productivity in the pasture, the experiment was canied out to determine the effect of infrequent, frequent defoliation or their alternation on change of its harvest yield and growth. Individual plants of Regal, Louisiana S-1, Grasslands Huia and Aberystwyth S184 were grown in 22cm plastic pot containing a 2 : 1 : 1 soil : sand : Peat moss mixture for 27 days after transplanting 50day seedlings raised on 3cm pots, and then all their fully expanded leaves are removed. Defoliation treatments were forced every 1 (CC, frequent), 4 week (RR, infrequent) or their alternations (CR, RC) after 8 weeks from the removal. To analyze the treatment effects, plants were sampled on 0 (the removal day), 4, 8, 12 and 16 weeks after the removal and seperated to leaves, petioles, stolons and roots. Each harvest yield of infrequent defoliation (RR) was higher than that of frequent defoliation (CC). Their alternations (RC, CR), however, forced fluctuation of the yield according to defoliation interval. Fraction weights from their altemations showed intermediate ones of infrequent and Frequent defoliation whose weights did the similar result to their harvest yields. Fraction and total dry weights per plant, shoot/root ratio were changed by relative span of defoliation interval, which resulted from the weights of leaves and petioles, removed parts. Root and total dry weight per plant of Regal were greater than the other cultivm in infrequent defoliation interval regardless of continuous or alternations. Productivity of white clover in pasture, therefore, can be controlled by alternation of infrequent and frequent defoliation or reverse.

• Advances in Traditional Medicine
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• v.3 no.2
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• pp.106-110
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• 2003

Respiratory syncytial virus (RSV) has long been considered an important cause of severe lower respiratory tract infection in infants and young children throughout the world. Unfortunately, no effective treatment of RSV exists. Therefore, New agents are needed to reduce the impact of RSV. We have studied the anti-viral effect of traditional Chinese midicinal herbs for over ten years and find Herba Patrinea (a Chinese medicinal herb) has the anti-RSV effect in vitro. In this study, the Herba Patrinea was extracted with hot water, condensed and sterilized. The cytotoxicity of the aqueous extract was tested by adding the diluted extract directly to HeLa cells and its effect on anti-RSV was estimated by the CPEI assay. As a result, the median cytotoxic concentration $(CC_{50})$ of Herba Patrinea was 32 mg/ ml by morphological observation, the median effective concentration (50% effective concentration, $EC_{50}$) of the Herba Patrinea against replication of the Long strain of RSV in HeLa cells were 1.25 mg/ml. The selectivity index $(SI=CC_{50}/EC{50})$ is 25.6. Moreover, Herba Patrinea gave a dose-dependent response in inhibiting RSV. In time of addition experiment, Herba Patrinea inhibited replication of RSV in HeLa cells when it was added at 0h, 2h, and 4h after virus infection. In summary, the results of this study suggest Herba Patrinea may be a novel anti-RSV drug and it is worthy of further studying.

• Phonetics and Speech Sciences
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• v.1 no.3
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• pp.151-154
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• 2009

The external ear generates resonance gain because of anatomical characteristics. The ear canal resonance is influenced by the length and volume of the ear canal, the pinna, the concha cavity, the body trunk, and the speed of sound wave. This study is focus on the influence of the volume of ear canal. 17-healthy-adult (32 ears) were participated. They did not have any medical and ear disease history. The maximum resonance frequency of the ear canal was 2675 (${\pm}265$) Hz at azimuth $0^{\circ}$ and 2784 (${\pm}268$) Hz at azimuth $45^{\circ}$. The resonance gain was 18.1 (${\pm}3.9$) dB at azimuth $0^{\circ}$ and 17.9 (${\pm}3.8$) dB at azimuth $45^{\circ}$, respectively. The ear canal volume was 0.78 (${\pm}0.2$) cc and 1.32 (${\pm}0.8$) cc including static compliance. The ear canal resonance was changed depending on the ear canal volume. It was also statistically correlated at azimuth $0^{\circ}$ (p=0.038) and $45^{\circ}$ (p=0.013), respectively. The resonance gain was not correlated with the ear canal volume. The change of resonance frequency according to the ear canal volume will be useful information in the field of audiological rehabilitation especially for hearing aids fitting. In addition, we expected this study can provide the basic information for the study of the external ear resonance characteristics.

• Journal of Periodontal and Implant Science
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• v.44 no.3
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• pp.141-146
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• 2014

Purpose: Peri-implantitis and periodontitis are inflammatory and infectious diseases of implant and tooth-supporting tissues. Recently, the role of gene polymorphisms of immune response components in the relevant pathogenesis has been investigated. The present study was the first to evaluate the relationship between two known single nucleotide polymorphisms (SNPs) of the receptor activator of nuclear factor kappa-${\beta}$ (RANK) gene (rs3018362 and rs35211496) in chronic periodontitis and peri-implantitis patients in an Iranian population. Methods: Eighty-one periodontally healthy patients, 38 patients with peri-implantitis, and 74 patients with chronic periodontitis were enrolled in this study. DNA was extracted from blood arm vein samples by using Miller's salting out technique according to the manufacturer's instructions given in the extraction kit. The concentration of DNA samples was measured using a spectrophotometer. The genetic polymorphisms of the RANK gene were evaluated using a competitive allele specific polymerase chain reaction (KBioscience allele specific PCR) technique. Differences in the frequencies of genotypes and alleles in the diseased and healthy groups were analyzed using chi-squared statistical tests (P<0.05). Results: Analysis of rs35211496 revealed statistically significant differences in the expression of the TT, TC, and CC genotypes among the three groups (P=0.00). No statistically significant difference was detected in this respect between the control group and the chronic periodontitis group. The expression of the GG, GA, and AA genotypes and allele frequencies (rs3018362) showed no statistically significant difference among the three groups (P=0.21). Conclusions: The results of this study indicate that the CC genotype of the rs35211496 RANK gene polymorphism was significantly associated with peri-implantitis and may be considered a genetic determinant for peri-implantitis, but this needs to be confirmed by further studies in other populations.

• BMB Reports
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• v.51 no.4
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• pp.163-164
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• 2018

CONSTANS (CO) induces the expression of FLOWERING LOCUS T (FT) in the photoperiodic pathway, and thereby regulates the seasonal timing of flowering. CO expression is induced and CO protein is stabilized by FLAVIN-BINDING KELCH REPEAT F-BOX PROTEIN 1 (FKF1) in the late afternoon, while CO is degraded by CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1) during the night. These regulatory cascades were thought to act independently. In our study, we investigated the relationship between FKF1 and COP1 in the regulation of CO stability in response to ambient light conditions. A genetic analysis revealed that FKF1 acts as a direct upstream negative regulator of COP1, in which cop1 mutation is epistatic to fkf1 mutation in the photoperiodic regulation of flowering. COP1 activity requires the formation of a hetero-tetramer with SUPPRESSOR OF PHYA-105 (SPA1), [$(COP1)_2(SPA1)_2$]. Light-activated FKF1 has an increased binding capacity for COP1, forming a FKF1-COP1 hetero-dimer, and inhibiting COP1 homo-dimerization at its coiled-coil (CC) domain. Mutations in the CC domain result in poor COP1 dimerization and misregulation of photoperiodic floral induction. We propose that FKF1 represses COP1 activity by inhibiting COP1 dimerization in the late afternoon under long-day conditions, resulting in early flowering.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.10 no.7
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• pp.1065-1073
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• 1999

This paper analyzed the ground bounce caused by the power plane resonance in the multilayered printed circuit board(PCB) using the Haar-wavelet-based Multiresolution Time-Domain (MRTD). In conventional Finite-Difference Time-Domain(FDTD), the highly fine vertical cell is needed to represent the distance between $V_{cc}$ plane and ground plane since the two planes are very close. Therefore the time step $\Deltat$ must be very small to satisfy the stability condition. As a result, a large number of iterations are needed to obtain the response in wanted time. For this problem, this paper showed that the computation time can be reduced by application of the MRTD method. The results obtained by the MRTD agree very well with those by FDTD method and analytic solutions. In conclusion, this paper proved the efficiency and accuracy of MRTD method for analyzing the EMI/EMC problems in PCB.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.24 no.5
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• pp.1001-1011
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• 2014

Smart Grid Devices could have security vulnerabilities that have legacy communication networks because of the fact that Smart Grid employs bi-directional communications and adopted a variety of communication interface. Consequently, it is required to build concrete response processes and to minimize the damage of the cyber attacks including security evaluation and certification methods. DCU is designed to collect meter data from numerous smart meter and send to utility's server so DCU installed between smart meter and utility's server. For this reason, If DCU compromised by attacker then attacker could use DCU to launching point for and attack on other devices. However, DCU's security evaluation and certification techniques do not suffice to be deployed in smart grid infrastructure. This work development DCU protection profile based on CC, it is expected that provide some assistance to DCU manufacturer for development of DCU security target and to DCU operator for help safety management of DCU.

• Journal of Ginseng Research
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• v.48 no.3
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• pp.310-322
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• 2024

Background: Osteosarcopenia is a common condition characterized by the loss of both bone and muscle mass, which can lead to an increased risk of fractures and disability in older adults. The study aimed to elucidate the response of various mouse strains to treatment with Rg3, one of the leading ginsenosides, on musculoskeletal traits and immune function, and their correlation. Methods: Six Collaborative Cross (CC) founder strains induced muscle atrophy and bone loss with dexamethasone (15 mg/kg) treatment for 1 month, and half of the mice for each strain were orally administered Rg3 (20 mg/kg). Different responses were observed depending on genetic background and Rg3 treatment. Results: Rg3 significantly increased grip strength, running performance, and expression of muscle and bone health-related genes in a two-way analysis of variance considering the genetic backgrounds and Rg3 treatment. Significant improvements in grip strength, running performance, bone area, and muscle mass, and the increased gene expression were observed in specific strains of PWK/PhJ. For traits related to muscle, bone, and immune functions, significant correlations between traits were confirmed following Rg3 administration compared with control mice. The phenotyping analysis was compiled into a public web resource called Rg3-OsteoSarco. Conclusion: This highlights the complex interplay between genetic determinants, pathogenesis of muscle atrophy and bone loss, and phytochemical bioactivity and the need to move away from single inbred mouse models to improve their translatability to genetically diverse humans. Rg3-OsteoSarco highlights the use of CC founder strains as a valuable tool in the field of personalized nutrition.