• Title/Summary/Keyword: CBF-CR

Search Result 2, Processing Time 0.016 seconds

Effects of Geopungjeseub-tang(Gufengchushi-tang) on the Changes of Cerebral Blood Flow in Rats (거풍제습탕이 뇌허혈이 유발된 백서의 뇌혈류 변화에 미치는 영향)

  • Hong, Seok;Jeon, Sang-Yun
    • The Journal of Internal Korean Medicine
    • /
    • v.26 no.3
    • /
    • pp.596-604
    • /
    • 2005
  • Objectives : Geopungjeseub-tang(Gufengchushi-tang) has been used in oriental medicine for many centuries as a therapeutic agent for hemiplegia caused by deficiency of qi(氣虛) and damp phlegm(濕痰). This study was performed to evaluate effects of Geopungjeseub-tang extract(GJT) on hemodynamics[regional cerebral blood flow(rCBF), pial arterial diameter(PAD), mean arterial blood pressure(MABP), heart rate(HR)] in normal rats and in rats with cerebral ischemia by middle cerebral artery(MCA) occlusion. Also, effects of adrenergic ${\beta}-receptor$, cyclooxygenase on response to GJT were evaluated. Methods : Laser-doppler flowmetry(LDF) measured changes of rCBF, MABP and HR. Video microscope and width analyzer measured changes in PAD. Results : rCBF and PAD increased after treatment with GJT(10mg/kg, i.v.) during the period of cerebral reperfusion, and pretreatment with indomethacin raised rCBF and PAD increased after treatment with GJT during the same period as above. Pretreatment with propranolol decreased rCBF, but increased after GJT treatment, but raised PAD increased after GJT treatment during this period of reperfusion. Conclusion : CR caused diverse responses were observed in rCBF and PAD after treatment with GJT. ACF action is mediated by adrenergic ${\beta}-receptor$ and cyclooxygenase. Result suggest that GJT has an anti-ischemic effect through the improvement of cerebral hemodynamics and has theraputic potential for cerebral apoplexy.

  • PDF

Random beamforming applying codebook rotation (다중 코드북을 이용한 랜덤 빔 형성 기법)

  • Kang, Ji-Won;Yoo, Byung-Wook;Seo, Jeong-Tae;Lee, Chung-Yong
    • Journal of the Institute of Electronics Engineers of Korea TC
    • /
    • v.46 no.7
    • /
    • pp.1-5
    • /
    • 2009
  • Random beanforming exploits multiuser diversity gain in static channels. Since the gain is restricted by the user population, some extended works have been proposed. Among them, a codebook-based opportunistic beamforming technique forms multiple random beams with small pilots. The technique however has difficulty in designing beams flexibly by the channel statistics. In this paper, we propose a technique forming the multiple random beams by rotating codebooks. The proposed technique enables the flexible design of beams so that multiuser diversity and beam selection diversity are exploited simultaneously with small pilots robust to the channel statistics.