• Title/Summary/Keyword: CAPE

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A Clinical Research about Herbal Cosmetics Containing Caffeic acid phenethyl ester Isolated from Vespae Nidus on the Whitening Effects (노봉방에서 추출된 카페인산 페네틸 에스테르가 함유된 한방화장품의 미백 개선에 관한 임상적 연구)

  • Cha, Ho-Yeol;Kim, Hee-Yeon;Ha, Ki-Tae;Cheon, Jin-Hong;Kim, Kibong
    • The Journal of Korean Medicine
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    • v.38 no.3
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    • pp.86-95
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    • 2017
  • Objectives: The purpose of this clinical research was to investigate the effects of herbal cosmetics containing Caffeic acid phenethyl ester (CAPE), an ingredient compound of various herbs including Vespae Nidus, on the Whitening Effects. Methods: A total of 20 subjects who visited Pusan National University Hospital from March 2nd, 2017 to April 11th, 2017 were included. In this study, we evaluated the visual evaluation, the melanin index (M) and erythema index (E) through skin analysis equipment, the subjective whitening improvement analysis, and the adverse reaction according to product use. Statistical analysis was performed with independent t-test and Mann-Whitney's U test. Statistical significance was achieved if the probability was less than 5% (p<0.05) Results: As a result of the visual evaluation, it was effective in improving skin whitening. The subjective whitening improvement analysis also showed positive results. However, no statistically significant differences were found between the test and control cosmetics in the melanin index (M) and erythema index (E) through skin analysis equipment. In the safety evaluation, some adverse reactions were reported, but no significant were observed directly from cosmetics. Conclusions: Considering the above results, we have confirmed the possibility of herbal cosmetics containing containing CAPE of Vespae Nidus Extracts.

Abnormal Behavior of Ordinary Heterotrophic Organism Active Biomass at Different Substrate/Microorganisms Ratios in Batch Test (회분식 실험 Substrate/Microorganisms 비에 따른 종속영양미생물의 특이거동 연구)

  • Lee, Byung-Joon;Wentzel, M.C.;Ekama, G.A.;Min, Kyung-Sok
    • Journal of Korean Society on Water Environment
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    • v.20 no.3
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    • pp.197-205
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    • 2004
  • Batch test methods have developed for a long time to measure kinetic and stoichiometric parameters which are required to perform steady state design and mathematical modelling of activated sludge processes. However, at various So/Xo ratios, abnormal behaviors of ordinary heterotrophic organism in batch tests have been reported in many researches. Thus, in this research, abnormal behaviors of heterotrophs in batch tests were investigated at various So/Xo conditions by measuring and interpreting oxygen utilization rate. As So/Xo ratio increased, the calculated values of maximum specific growth rates, ${\mu}_{H,max}$ and $K_{MP,max}$, increased. However, at a certain point of So/Xo (around 10mgCOD/mgMLAVSS), ${\mu}_{H,max}$ and $K_{MP,max}$ values started to decrease. According to this observation, three prominent behaviours of heterotrophs were identified at various So/Xo conditions. (1) At low So/Xo region (below 5 mgCOD/mgMLAVSS), the oxygen utilization rate of heterotrophs in batch tests were almost stable and consequently yielded lower maximum specific growth rate. (2) At high So/Xo region (up to 5~10 mgCOD/mgMLAVSS), oxygen utilization rate incresed sharply with time and indicated more upward curvature than the predicted OUR with conventional activated sludge model, which consists of single hetetrotrophs group. Thus, in this region, competition model of two organisms, fast-grower and slow-grower, seemed to be appropriate. (3) At extremely high So/Xo region (over 10mgCOD/mgMLAVSS), significant oxygen utilization rate was still observed even after depletion of readily biodegradable COD. This might be caused by retarded utilization of intermediates which were generated by self inhibition mechanism in the process of RBCOD uptake.

A Study on the Design and Composition of Victorian Women's Mantle

  • Lee, Sang-Rye;Kim, Hye-Jeong
    • Journal of Fashion Business
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    • v.14 no.6
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    • pp.188-203
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    • 2010
  • This study purposed to identify the design and composition characteristics of mantle through a historical review of its change and development focusing on women's dress. This analysis was particularly focused on the Victorian age because the variety of mantle designs introduced and popularized was wider than ever since ancient times to the present. For this study, we collected historical literature on mantle from ancient times to the $19^{th}$ century and made comparative analysis of design and composition, and for the Victorian age we investigated also actual items from the period. During the early Victorian age when the crinoline style was popular, mantle was of A.line silhouette spreading downward from the shoulders and of around knee length. In the mid Victorian age from 1870 to 1889 when the bustle style was popular, the style of mantle was changed to be three-dimensional, exaggerating the rear side of the bustle skirt. In addition, with increase in women's suburban activities, walking costume became popular and mantle reached its climax. With the diversification of design and composition in this period, the name of mantle became more specific and as a result, mantle, mantelet, dolman, paletot, etc. were used. The styles popular were: it looked like half-jacket and half-cape. Ornaments such as tassels, fur, braids, rosettes, tufts and fringe were attached to create luxurious effects. In the late Victorian age when the hourglass style was in fashion, mantle returned again to plain design emphasizing the details of the shoulders. The results of this study are expected to present motives for the development of contemporary designs, to contribute to the new recognition of the value of mantles, and to open a new research area of clothing history.

The Study on the Conservation According to Analysis of Composition of Canopied Landscape - A Case of Chongju Garosoo-gill- (관개경관 구도분석에 따른 보전방안에 관한 연구 - 청주 가로수길 중심으로 -)

  • Kwon Sang Zoon;Hong Young Rok
    • Journal of Environmental Science International
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    • v.14 no.4
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    • pp.379-387
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    • 2005
  • This study aims to establish the schematic plan for renewing canopied landscape of Garosoo-gil of Chongju and to review to conserving the resources of streetscape of the Garosoo-gil. The study reinterpreted the Garosoo-gil of tree canopied road, representing meanings and functions of the road with main traffics as well as the image of Chongju city achieved buffer zone for open spaces to city green network. The study relied on the present composition, the status of road trees and streetscapes; additionally, the present streets cape was performed with examinations of those factors, the composition of roadscape, the change of structure according to visitor's movement and road construction condition, which was composed with focused places on concerning the loss and demolition of trees by Garosoo-gil. According to the result, the streetscape could be prospected to decreasing the number of trees and changing the sceneries of streetscape. As a result, the dominant canopied streetscape was found three areas. The analysis could help to find a way to establish the schematic plan for making the streets cape be symbolized and take place identified and better festival events with greens. The study could not only suggest the place of the streetscape to be divided into conservation area and protection area, for tree canopy but also establish alternatives for making the Garosoo-gil be a beautiful street park and enduring for a better landscape of main entrance road.

Observation of Along-shore Current in the Northern East Sea by SARAL/AltiKa Sea Level Data (SARAL/Altika 해표면 고도 위성에 의한 동해 북부 연안 해류)

  • LEE, DONG-KYU;CHOI, JANG-GEUN
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.24 no.3
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    • pp.429-435
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    • 2019
  • The drifters of the Global Drifter Program were deployed in the northern East Sea for two years from March 2015 to compare and validate currents estimated from sea-level measurements with the SARAL/AltiKa altimetry satellite mission, specially designed to accurately measure sea level in the near-coastal area. The collocated (less than 20 km apart) directly measured current from GPS locations every 30 minutes and the currents normal to the satellite tracks show a similar correlation in the area shallower than 200 m depth as the open ocean and it makes it possible to investigate the time variations of the current along the coast in the northern East sea, where direct observations of current are scarce. The Liman Current along the Siberian coast is found to be southward all year round, but the North Korean Cold Current flows southward only in the summer. The North Korean Cold Current south of the Musudan cape mostly flows to the south, but the current direction depends on the presence of an eddy around the coast of Musudan cape.

Development of Safety Clothing for Sports and Entertainment for Adolescent (청소년을 위한 스포츠 및 엔터테인먼트 안전의복의 개발)

  • Park, Soon Ja;Ko, Soo Kyung
    • Human Ecology Research
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    • v.59 no.1
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    • pp.83-97
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    • 2021
  • This study developed safety clothing that is essential for adolescent to protect their bodies from accidents, pursue activities and individuality. Therefore, the developed safety clothing was first based on international standards, while changing design to emphasize creativity, activity, and functionality. Two suits of boy's clothes and a girl's suit were developed as safety clothing for sportswear, along with two pairs of girl's clothes and a pair of boy's clothes for entertainment. It was confirmed that the difference in visibility was revealed by testing under different lighting conditions. Second, the survey on adolescents indicated no significant gender difference in sportswear. Round shirt+shorts for both boys and girls were the most preferred for ball game sportswear. However, there was a significant difference by gender in the design of safety clothing for entertainment. Male students preferred jump suit=cape+pants the most, and female students preferred jump suit>cape+pants in the order (p<0.05). In the safety clothes with the highest preference for entertainment, there was no gender difference. All students preferred the jump suit at the most. Checking at each school level, it was found that both middle and high school students preferred jump suit designs, and in safety clothing, middle school students preferred high-neck shirt blouse+tight skirt, and high school students preferred jump suits. Third, 35.5% responded that they would wear it more if current safety clothing is improved. This indicated the necessity of developing various safety clothing for adolescence.

Trans-10, cis-12 Conjugated Linoleic Acid Modulates Nuclear Factor-${\kappa}B$ p65 Activity on the Production of Tumor Necrosis Factor-${\alpha}$ in Porcine Peripheral Blood Mononuclear Cells (돼지 말초혈액 단핵구세포에서 trans-10, cis-12 conjugated linoleic acid의 TNF-${\alpha}$ 생산에 대한 nuclear factor-${\kappa}B$ p65 활성 조절 효과)

  • Kim, Young-Beum;Lee, Ill-Woo;Kang, Ji-Houn;Yang, Mban-Pyo
    • Journal of Veterinary Clinics
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    • v.28 no.2
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    • pp.190-195
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    • 2011
  • Nuclear factor ${\kappa}B$ (NF-${\kappa}B$) is a nuclear transcription factor that modulates the expression of inflammatory cytokines such as tumor necrosis factor (TNF)-${\alpha}$. trans-10, cis-12 (t10c12)-conjugated linoleic acid (CLA) participates in the inhibition of TNF-${\alpha}$ production upon lipopolysaccharide (LPS)-stimulation. However, in our previous study, t10c12-CLA enhanced the production of TNF-${\alpha}$ by LPS-unstimulated porcine peripheral blood mononuclear cells (PBMCs) and RAW 264.7 macrophages in vitro. To resolve this apparent contradiction, we hypothesized that the effect of t10c12-CLA on TNF-${\alpha}$ production depends on NF-${\kappa}B$ activation induced by LPS stimulation. To test this hypothesis, we assessed the in vitro effect of t10c12-CLA on TNF-${\alpha}$ production and NF-${\kappa}B$ p65 activity in LPS-stimulated and LPS-unstimulated porcine PBMCs. t10c12-CLA treatment resulted in increased TNF-${\alpha}$ production by LPS-unstimulated PBMCs but decreased TNF-${\alpha}$ production by LPS-stimulated PBMCs. t10c12-CLA increased the degradation of inhibitory ${\kappa}B$ ($I{\kappa}B$)-${\alpha}$ protein and activated NF-${\kappa}B$ p65 in LPS-unstimulated PBMCs, but had the opposite effect in LPS-stimulated PBMCs. Notably, t10c12-CLA enhanced NF-${\kappa}B$ p65 binding activity in LPS-unstimulated PBMCs exposed to caffeic acid phenethyl ester (CAPE), a NF-${\kappa}B$ inhibitor. Conversely, it inhibited NF-${\kappa}B$ p65 binding activity in LPS-stimulated PBMCs exposed to CAPE. These results suggest that t10c12-CLA may have different actions under different physiological conditions, and that its effect may be associated with a change in NF-${\kappa}B$ p65 activity.

An Case Study of the Direct Payment Program for Rural Landscape Conservation - Environmental Stewardship in England - (농촌경관 보전을 위한 보조금 지원제도 연구 -영국의 환경관리제(Environmental Stewardship)를 중심으로-)

  • Chae, Hye-Sung;Ahn, Tong-Mahn
    • Journal of Korean Society of Rural Planning
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    • v.14 no.2
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    • pp.65-75
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    • 2008
  • Recently the program of direct payment for rural landscape conservation attracts great interests as it may help disadvantaged rural people. Recognized the effect of the program to improve the rural landscape and economy, it has been suggested that the program of direct payment for rural landscape conservation should be expanded. This paper presents the measures and status of Environmental Stewardship, the direct payment program for landscape conservation in England, as following; 1) rural development policies in UK organized under EU, 2) measures and agreements for rural landscape management, 3) the statues of ES enforcement. We sampled a pilot farm, surveyed inside and outside landscape of the farm, and interviewed local government officers and farmers in order to find policy implication.

Use of Mobile Phones and Cancer Risk

  • Ayanda, Olushola S.;Baba, Alafara A.;Ayanda, Omolola T.
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.1
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    • pp.403-406
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    • 2012
  • Mobile phones work by transmitting and receiving radio frequency microwave radiation. The radio frequency (RF) emitted by mobile phones is stronger than FM radio signal which are known to cause cancer. Though research and evidence available on the risk of cancer by mobile phones does not provide a clear and direct support that mobile phones cause cancers. Evidence does not also support an association between exposure to radio frequency and microwave radiation from mobile phones and direct effects on health. It is however clear that lack of available evidence of cancer as regards the use of mobile phone should not be interpreted as proof of absence of cancer risk, so that excessive use of mobile phones should be taken very seriously and with caution to prevent cancer.

Basic Study on Radio-Wave Interference Assessment of Wind Turbines (풍력발전기에 의한 전파간섭 영향평가 기초연구)

  • Kim, Hyun-Goo;Kim, Hyo-Tae
    • 한국신재생에너지학회:학술대회논문집
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    • 2006.11a
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    • pp.305-306
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    • 2006
  • This paper introduces a radio-wave interference assessment of wind turbines that were planned to be installed at Homi-Cape in Pohang region where wind resource has been evaluated worthwhile developing a wind farm. In that area, AM radio station with two antennas and a harbor radar facility are located so that radio-wave coupling is inevitable if the wind farm is designed without considering radio-wave environmental impact. A low-frequency analysis using MoM (Method of Moment) is used to examine interference effect caused by wind turbines and an optimal layout minimizes coupling effect is presented.

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