• Journal of the Korean Institute of Telematics and Electronics A
• /
• v.32A no.4
• /
• pp.93-102
• /
• 1995

This paper introduces a general purpose Associative Processor(AP) which is very efficient for search-oriented applications. The proposed architecture consists of three main functional blocks: Content-Addressable Memory(CAM) arry, row logic, and control section. The proposed AP is a Single-Instruction, Multiple-Data(SIMD) device based on a CAM core and an array of high speed processors. As an application for the proposed hardware, we present a parallel algorithm to solve a global routing problem in the layout process utilizing the processing capabilities of a rudimentary logic and the selective matching and writing capability of CAMs, along with basic algorithms such a minimum(maximum) search, less(greater) than search and parallel arithmetic. We have focused on the simultaneous minimization of the desity of the channels and the wire length by sedking a less crowded channel with shorter wire distance. We present an efficient mapping technique of the problem into the CAM structure. Experimental results on difficult examples, on randomly generated data, and on benchmark problems from MCNC are included.

• Smart Media Journal
• /
• v.12 no.9
• /
• pp.45-59
• /
• 2023

Weakly supervised object localization (WSOL) is a task of localizing an object in an image using only image-level labels. Previous studies have followed the conventional class activation mapping (CAM) pipeline. However, we reveal the current CAM approach suffers from problems which cause original CAM could not capture the complete defects features. This work utilizes a convolutional neural network (CNN) pretrained on image-level labels to generate class activation maps in a multi-scale manner to highlight discriminative regions. Additionally, a vision transformer (ViT) pretrained was treated to produce multi-head attention maps as an auxiliary detector. By integrating the CNN-based CAMs and attention maps, our approach localizes defective regions without requiring bounding box or pixel-level supervision during training. We evaluate our approach on a dataset of apple images with only image-level labels of defect categories. Experiments demonstrate our proposed method aligns with several Object Detection models performance, hold a promise for improving localization.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.31 no.6
• /
• pp.1134-1141
• /
• 2002

Adhesion of leukocytes to the activated vascular endothelium and their subsequent recruitment/migration into the artery wall are key features in the pathogenesis of atherosclerosis and inflammatory diseases. These features have been mediated by cell adhesion molecules including vascular cell adhesion molecule-1 (VCAM-1) and in tracellular cell adhesion molecule-1 (ICAM-1). This study examined whether flavonoids inhibit the pro-inflammatory cytokine TNF-$\alpha$-induced monocyte adhesion via a modulation of the protein expression of VCAM-1 and ICAM-1 of human umbilical vein endothelial cells (HUVECs). TNF-$\alpha$ markedly increased the adhesion of THP-1 monocytes to endothelial cells and induced the expression of VCAM-1, ICAM-1 and E-selectin proteins in HUVECs. Micromolar concentrations of the flavones luteolin and apigenin and the flavonol quercetin near completely blocked the monocyte adhesion to the activated endothelial cells and the induction of these adhesion molecules. However, equimicromolar catechins of (-)epigallocatechin gallate and (+)catechin, the flavonol myr- icetin and the flavanones of naringin and hesperidin had no effect on TNF-$\alpha$-activated monocyte adhesion. (-)Epigallocatechin gallate, (+) catechin, and naringin did not attenuate the TNF-$\alpha$ induction of these adhesion molecules. Furthermore, culture with luteolin and apigenin strongly blocked the expression of TNF-$\alpha$-induced VCAM-1 mRNA and modestly attenuated ICAM-1 mRNA. Quercetin modestly decreased the TNF-$\alpha$-activated VCAM-1 and ICAM-1 mRNAs. These results demonstrate that flavonoids classified as flavones and flavonols may inhibit monocyte adhesion to the TNF-$\alpha$-activated endothelium, most likely due to a blockade of expression of functional adhesion molecules down-regulated at the transcriptional level, indicating a definite linkage between the chemical structure of flavonoids and the expression of cell adhesion molecules. Furthermore, the antiathero-genic feature of flavonoids appears to be independent of their antioxidant activity.

• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.4
• /
• pp.1419-1424
• /
• 2012

Objectives: To investigate in depth the use of complementary and alternative medicines (CAMs) by cancer patients at the end-of-life (EOL) and how they communicate with physicians about them. Design and location: In 17 hospitals in Korea between January and December 2004 we identified 4,042 families of cancer patients. Results: The prevalence of CAM use among cancer patients at the EOL was 37.0%, and 93.1% had used pharmacologic types of agents. The most frequent motive for CAM use was the recommendation of friends or a close relative (53.4%) or a physician (1.6%). Only 42.5% discussed CAM use with their physicians. Satisfaction with CAMS was recalled for 37.1%. The most common reason given for that satisfaction was improvement of emotional or physical well-being, while ineffectiveness was the most common reason given for dissatisfaction. The average cost of CAM during the last month of life was $US 900. CAM use was associated with longer disease periods, primary cancers other than liver, biliary, and pancreatic, and need of support from physicians or religion. Conclusions: CAM use among cancer patients at the EOL was common, not discussed with physicians, and associated with expectation of cure. Expectations were generally unmet while the treatments were a financial burden. Further studies evaluating the effects of CAM at the EOL and factors that enhance communication with the physician are needed.

• Journal of Microbiology and Biotechnology
• /
• v.11 no.4
• /
• pp.656-662
• /
• 2001

Angiogenesis is known as a crucial process in the growth and spreading of tumor cells. Accordingly, the effective inhibition of this process would appear to be a promising way to cure angiogenesis-related diseases, including cancer. This study demonstrates that acalycixenolide E (AX-E) from the marine organism Acalycigorgia inermis exhibits a potent anti-angiogenic activity both in vitro and in vivo. AX-E inhibits the bFGF-induced proliferation of HUVECs in a dose dependent manner, along with the bFGF-induced migration, invasion, and tube formation of HUVECs. Moreover, AX-E potently inhibits the in vivo neovascularization of the chorioallantoic membranes (CAMs) of growing chick embryos. interestingly, AX-E suppresses the expression of metalloproteases 2 and 9, yet shows no effect on their activities. The novel chemical structure and potent anti-angiogenic activity of AX-E will be of great value in elucidating the molecular mechanism of angiogenesis as well as in the development of a novel anti-angiogenic drug.

• Journal of Broadcast Engineering
• /
• v.23 no.1
• /
• pp.63-73
• /
• 2018

These days, VR contents are created in three ways: CG based method, game engine based method, and live action shooting method. The most universal method is live action shooting. So far, most live actions are shot with action cams. Therefore, this method is different from professional image production method for movies and TV dramas. This study tries to point out the difference between professional image production method and action cam based shooting method, and proposes an alternative. The proposed method is log shooting based HDR filming and editing. As the result of test shooting and editing, the proposed method was able to obtain more color information than conventional action cam based shooting method and thereby to implement high-definition images which are hard in an action cam.

• Korean Journal of Veterinary Service
• /
• v.20 no.1
• /
• pp.95-102
• /
• 1997

Author investigated internal parasitism for the feces of dog's training center, breeding-dog farm, dairy farm, home by 120 indoor breeding dog and 566 outdoor one in Inchon area. This survey was done from February in 1994 to December in 1995. 1. As a result of total 686 samples, positives were 373(54.4%). Among them, indoor and outdoor breeding dogs were 21(3.1%) 352(51.3%), respectively. 2. According to breeding, it was manifested that 21samples (17.5%) of 120 indoor breeding dogs were positive, and 352 samples(62.2%) of outdoor breeding were positive. 3. The infection rate of dogs for food in dairy farm, breeding dogs in the farm, dog of training center and dog of house is high in order. 4. Infection rate of parasites in 24 dogs breeds, Mongrel dogs were 81.3%, Shepherds were 80.0%, Tosas were 78.4%, Akida and Siberian huskys were 76.2%, Jindos were 55.5%, Pointers were 50.0%, although Afghan hound, Spanial, Shin-tzu, Maltis and Buldog were examined as aparasites negative. 5. After administration with vermicide parasites infection rate were 43.0% in two months. In four months, it were 66.7%, and dogs without vermicide were 87.0%. It seemed like that further research about dosage of vermicide is needed. 6. The rate of single-infection was 37.6% and that of mixed-infection was 16.8%. Among classified 13 types, Ancylostoma caninum 35.6%, Toxocara cams 11.2%, Isospora sp 9.3%, Toxascaris leonina 5.1%, Trychuris vulpis 4.4% were investigated.

• The KSFM Journal of Fluid Machinery
• /
• v.12 no.3
• /
• pp.31-37
• /
• 2009

This paper presents a implantable intrathecal drug infusion pump for pain control in cancer patients. This device consists of micropump module, drug reservoir module and control module. The micropump module using cam-follower mechanism composed of small-sized four cams and four followers. Each followers is driven by a cam and liquid is discharged by a sequential reciprocal motion of the followers. The advantage of this structure is that it allows the pump to be clean and valveless. The drug reservoir module composed of drug chamber, gas chamber and diaphragm. The control module composed of battery, wireless communication unit and controller. To design a small-sized, low power pump some analysis were performed to determine the design parameters. To verify the feasibility of the experiment, a prototype was manufactured and its operating characteristics were investigated. Experimental results were in accordance with the expected results obtained from analysis.

• Journal of the Korean Society of Manufacturing Process Engineers
• /
• v.15 no.1
• /
• pp.74-80
• /
• 2016

Due to the increased use of power caused by industrial development, the importance of improving wear and friction in the contact region has emerged. Except for some parts, such as brakes or clutches and friction, seals and precision mechanical parts (e.g., pistons, bearings, valves, and cams) are important engine components that require low friction characteristics. In this study, the experimental method used to determine the friction characteristics was based on the type of rpm with the pin-on-disc test device, the element analysis program ANSYS was used to analyze the surfaces of the two metals rubbing together, and physical formation FEM models were used to study the properties and wear. The friction coefficient of variation was unsafe, but at the start of wear, it converged to a stable friction coefficient that increased after a certain slip away.

• Journal of the Korean Society for Precision Engineering
• /
• v.26 no.5
• /
• pp.112-119
• /
• 2009

Cam mechanisms are one of the most popular devices for generating irregular motion and are widely used in many automatic equipments, such as textile machinery, internal combustion engines and other automatic devices. In order to obtain the positive motion of follower by rotating cam, its shape should be correctly designed and manufactured. However, complex engineering tasks are required in a design and manufacturing of cams. And also, the manufacturing of general cam is demanded high costs. For the designing of cam, it must be decided that what kind of motion has to be transmitted to follower before selecting the curve of cam and designing profile of cam. However, even though the exact profile of cam is designed at the progress of design, if it doesn't have precision at the manufacturing progress, it's impossible to get expected result. We will develop cam simulation apparatus for measuring cam curve and get profile data before analyzing an error through comparison with design data of cam.