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Factors Associated with Changes in Bone Mineral Content among Girls in Early Pubertal Age (사춘기 초기 여자 어린이의 골질량 변화와 이에 영향을 미치는 요인 분석)

  • Yun, So-Yoon;Park, Min-Kyoung;Paik, Hee-Young;Joung, Hyo-Jee
    • Journal of Nutrition and Health
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    • v.40 no.1
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    • pp.69-77
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    • 2007
  • The study was conducted to investigate the factors associated with bone mineral content (BMC) changes among early pubertal aged girls. Two hundred and thirty girls between 9 to 11 years of age participated in (our surveys over 2 year period. During each survey, dietary intakes were collected with 3-day food records, BMC of left leg's calcaneus were measured by PIXI (Lunar Ltd.) and body composition was measured by bioimpedance method (Inbody 3.0 Biospace Co. Ltd, Seoul, Korea). Mean values of BMC increased in consecutive measurements -1.48 g, 1.54 g, 1.61 g and 1.66 g. The change of BMC between the first and last measurements was significantly positively correlated with % body fat, negatively correlated with BMC at the baseline (p < 0.05). Change of BMC was also significantly positively correlated with % change of lean mass and mineral mass between the first and last measurements. Nutrient intakes during the study period were calculated as mean daily intakes from all surveys. Mean daily intakes of Vit. C and Vit. $B_6$ were positively and isoflavone intake was negatively correlated with changes of BMC (p < 0.05). In stepwise regression of BMC change with body composition and nutrient intakes, baseline values of BMC, weight, BMI and age, % change of mineral mass during the study period, mean intakes of isoflavone, Vit. $B_6$, protein, carotene and zinc were significant explanatory variables ($R^2=0.38$, p <.001, F = 32.39). The results imply that the change of BMC among early pubertal aged girls are associated with some body composition and intakes of certain nutrients.

Effect of Cr content on the FAC of pipe material at 150℃ (150℃에서 원전 2차측 배관재료의 Cr함량에 따른 유체가속부식 특성)

  • Park, Tae Jun;Kim, Hong Pyo
    • Corrosion Science and Technology
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    • v.12 no.6
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    • pp.274-279
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    • 2013
  • Flow accelerated corrosion (FAC) of the carbon steel piping in nuclear power plants (NPPs) has been major issue in nuclear industry. During the FAC, a protective oxide layer on carbon steel dissolves into flowing water leading to a thinning of the oxide layer and accelerating corrosion of base material. As a result, severe failures may occur in the piping and equipment of NPPs. Effect of alloying elements on FAC of pipe materials was studied with rotating cylinder FAC test facility at $150^{\circ}C$ and at flow velocity of 4m/s. The facility is equipped with on line monitoring of pH, conductivity, dissolved oxygen(DO) and temperature. Test solution was the demineralized water, and DO concentration was less than 1 ppb. Surface appearance of A 106 Gr. B which is used widely in secondary pipe in NPPs showed orange peel appearance, typical appearance of FAC. The materials with Cr content higher than 0.17wt.% showed pit. The pit is thought to early degradation mode of FAC. The corrosion product within the pit was enriched with Cr, Mo, Cu, Ni and S. But S was not detected in SA336 F22V with 2.25wt.% Cr. The enrichment of Cr and Mo seemed to be related with low, solubility of Cr and Mo compared to Fe. Measured FAC rate was compared with Ducreaux's relationship and showed slightly lower FAC rate than Ducreaux's relationship.

Effect of Soil Grinding on Total Concentrations of As and Pb in Soil Determined by aqua regia Method (토양시료의 분쇄가 왕수분해법을 이용한 비소와 납의 전함량 분석 결과에 미치는 영향)

  • An, Jinsung;Yu, Gihyeon;Nam, Kyoungphile
    • Journal of Soil and Groundwater Environment
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    • v.23 no.1
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    • pp.25-29
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    • 2018
  • The effect of soil grinding on total As and Pb concentrations determined by aqua regia method was examined. Among six field-collected, air-dried soil samples tested, soils A, B, C, and E were directly sieved through a $150-{\mu}m$ sieve without grinding and showed 2.18 to 3.03 times higher total As concentrations and 2.62 to 3.45 times higher total Pb concentrations than those of the soil samples prepared to allow all soil particles to pass through the $150-{\mu}m$ sieve by grinding. The reason can be ascribed to the fact that those soils contain fine particles (i.e., < $150{\mu}m$ in diameter) only 4.6 to 6.8% of the total soil weights. On the other hand, for D and F soils, fine particles smaller than $150{\mu}m$ accounted for 57 and 46%, respectively, so that the effect of grinding on As and Pb concentrations were relatively low (As: 1.15 and 1.23 times, Pb: 1.36 and 1.49 times, respectively). The result demonstrates that grinding prior to $150-{\mu}m$ sieving is necessary to ensure the homogeneity of soil samples and hence to obtain more accurate heavy metal concentrations in soils. This is especially true for soil samples with less fine soil particles and/or microaggregates (i.e., below $150{\mu}m$).

A Clinical Study of the Medistinal Tumors and Cysts -27 cases analysis (종격동 종양 및 낭종 27례에 대한 임상적 고찰)

  • 장진우;황상원
    • Journal of Chest Surgery
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    • v.30 no.4
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    • pp.408-412
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    • 1997
  • We have experienced 27 cases of primary medistinal tumors and cyst from April, 1986 to April 1996. At Masan Samsung General Hospital. The results of the anslysed were as follows 1. Of 27 medistinal tumors and c,pests, 9 patients were male and 18 patients were female(m : f= 1 : 2) 2. The most common chief complaint was chest discomfort or pain(8 cases 30 %) and 17 patients(63%) were asymptomatic. 3. The most common primary medistinal tumor was Neurogenic tumor in 9 cases(33 %) followed by Thymoma in 7 cases(26 %), teratoma in 6 cases(22 %) 4. The incidence of malignancy of all case was 3 cases(11 %), all cases were symptomatic and the most common malignancy was malig. thymoma(3 cases,43 %) 5. The anterior mediastinum was the most common tumor location with 15 cases(56 %) followed by posterior 11(41 %) and middle mediastinum 1(4 %). Anterior mediastinum tumors were predominantly thymomas and teratoma and posterior mediastinal tumors were neurogenic tumors 6. Complete removal of tumor was achieved in 26 cases(96 %) and open biopsy was done on 1 case 7. Postoperative complications were continued lumbar shunt drainage in 1 case and wound infection in 1 case 8. There was no case of postoperative mortality and good clinical course in surgically completely rejected cases

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A Study on Electrophoretic Pattern and Immunosuppressive Activity of Uterine Secretory Protein in Early Pregnant Sows (초기 임신돈에 있어서 자궁분비단백질의 전기영동상과 면역억제력에 관한 연구)

  • 김경순;정영채;김창근;한기영;김형태;윤종택;김종대;최선호
    • Korean Journal of Animal Reproduction
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    • v.13 no.3
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    • pp.179-187
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    • 1989
  • The experiment was carried out to study the profile of uterine specific protein during early pregnancy in sows and to test it's immunosuppressive activity. Uterine protein samples were obtained by flushing the uterine horn on Day 3, 6, 9, 12 and 15 of the estrous cycle and the pregnancy respectively and the protein concentration of each sample was determined. The change of uterine protein was examined by sodium dodecyl sulfate(SDS)-PAGE. The immunosuppressive activity of uterine secretory protein was investigated according to the lymphocyte blastogenesis response to mitogen. The results of this experiment are summarized as follows ; 1. The uterine protein during estrous cycle and early pregnancy was relatively constant up to Day 9, but increased on Day 12. Maxium total protein values were found on Day 15. The concentration of serum proteins were about 82-95 mg during estrous cycle, but decreased to about 70-82 mg during early pregnancy. 2. The proteins components similar electrophoretic patterns(PAGE) that were no differences (band ; a, b, c, d, e, f, g, I) on Days 3, 6 and 9 of the estrous cycle and pregnancy. But there were more 2 bands specifically on Day 12 of the pregnancy and on Day 15 of estrous cycle and showed more 4 bands on Day 15 of early pregnancy. They seemed to be acidoprotein and their average molecular weight were 38,000, 22,300 and 12,600. 3. When uterine protein were added 500$\mu\textrm{g}$/ml, there was no immunosuppresive activity on Day 3 of estrous cycle and lymphocyte blastogenesis was slightly suppressed on Day 3 of pregnancy. The immunosuppressive activity on Day 9 of estrous cycle and pregnancy appeared in 500$\mu\textrm{g}$/ml and 150$\mu\textrm{g}$/ml, respectively the uterine protein on Day 12 and 15 showed immunosuppresive activity, which at the level of 150$\mu\textrm{g}$/ml during non-pregnancy and at the level of 100 to 125$\mu\textrm{g}$/ml during early pregnancy, respectively.

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BIOACTIVE PEPTIDES DERIVED FROM FOOD PROTEINS AND PREVENTION OF LIFE-STYLE RELATED DISEASES

  • Yoshikawa Masaaki
    • Proceedings of the Korean Society of Food Science and Nutrition Conference
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    • 2001.12a
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    • pp.69-73
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    • 2001
  • Two opioid peptides, YPLDL and YPLDLF, were isolated from enzymatic digests of spinach ribulose-1, 5-bisphosphate carboxylase/oxygenase (RuBisCO) and named rubiscolin-5 and -6, respectively. These peptides were selective for delta-receptor and the latter was about 3 times more potent than the former. After oral administration in mice at the dose of 100 mg/kg, rubiscolin-6 showed analgesic activity in tail pinch test. It also stimutated learning performance at the same dose in passive avoidance experiment using step-through apparatus. An immunostimulating peptide, MITLAIPVNKPGR, was isolated from a trypsin digest of soybean protein and named soymetide. Immunostimulating activy of soymetide was mediated by fMLP receptor. Interestingly, after oral administration in rats at a dose of 300 mg/kg (po.), soymetide-4 (MITL) protected alopecia (hair-loss) induced by etoposide, a cancer chemotherapy agent. Stimulation of IL-1 release by the peptide was involved in the mechanism. Ovokinin(2-7), RADHPF, is a vasorelaxing peptide released from ovalbumin by the action of chymotrypsin. It lowered blood pressure of spontaneously hypersensive rats (SHR) after oral administration at a dose of 10 mg/kg. RPLKPW, which was designed by replacing 4 amino acid residues in ovokinin(2-7), exhibited hypotensive activity at a dose of 0.1 mg/kg (po.). This peptides was introduced into 3 homologous sites in soybean beta-conglycinin alpha' subunit by site-directed mutagenesis of the cDNA and expressed in E. coli. The minimum effective dose for hypotensive activity of the genetically modified beta-conglycinin alpha' subunit was 10 mg/kg (po.), which is about 1/200 that of ovalbumin.

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Effect of Chronic Treatment of Ginseng Extract on the Clearance of Blood Carbon Monoxide in Rat (인삼추출물의 장기적인 급여가 흰쥐의 혈중 CO-Hb 제거에 미치는 영향)

  • Lee, Young-Gu;Sohn, Hyung-Ok;Lim, Heung-Bin;Lee, Dong-Wook
    • Journal of Ginseng Research
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    • v.19 no.3
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    • pp.225-230
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    • 1995
  • The effect of long-term ginseng (Panax ginseng C.A. Meyer) administration on the clearance of carboxyhemoglobin (CO-Hb) and the property of blood gases was investigated in rats. Rats were received ginseng water extract (0.025% in drinking water) for 42 weeks starting at the age of 6 weeks. They were exposed to the diluted mainstream smoke generated from 15 filter cigarettes for 20 min in a round polycarbonate chamber (D37 cmXH13 cm). Under this condition, the mean CO-Hb content of control and the ginseng-treated rats immediately after the exposure was nearly the same as 13.8$\pm$2.9 f) and 13.9$\pm$1.6%, respectively. However, CO-Hb was more rapidly removed from blood in the ginseng treated rats than in untreatEd control with the laps of time, namely, its biological half life In the former was 36.9$\pm$1.5 min and in the latter was 56.9$\pm$13.2 min. Although long-term ginseng treatment did not affect the content of hemoglobin and blood pH of rats, it slightly increased blood oxygen content and its partial pressure value, and decreased levels of carbon dioxide and bicarbonate. These results suggest that long-term administration of rats with ginseng extract accelerate the elimination of CO from the blood. This effect seems to be related to the enhancement of oxygen consumption of the rat by a certain action of ginseng components as previously reported.

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Comparative Analysis of Strengthening with Respect to Microstructural Evolution for 0.2 Carbon DP, TRIP, Q&P Steels

  • Jin, Jong-Won;Park, Yeong-Do;Nam, Dae-Geun;Lee, Seung-Bok;Kim, Sung-Il;Kang, Nam-Hyun;Cho, Kyung-Mox
    • Korean Journal of Materials Research
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    • v.19 no.6
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    • pp.293-299
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    • 2009
  • The microstructures and mechanical properties of Dual Phase (DP), Transformation-Induced Plasticity (TRIP), and Quenching & Partitioning (Q&P) steels were investigated in order to define the strengthening mechanism of 0.2 C steel. An intercritical annealing between Ac1 and Ac3 was conducted to produce DP and TRIP steel, followed by quenching the DP and TRIP steel being quenched at to room temperature and by the TRIP steel being austemperingaustempered-air cooling cooled the steel toat room temperature, respectively. The Q&P steel was produced from full austenization, followed by quenching to the temperature between $M_s$ and $M_f$, and then enriching the carbon to stabilize the austenite throughout the heat treatment. For the DP and TRIP steels, as the intercritical annealing temperature increased, the tensile strength increased and the elongation decreased. The strength variation was due to the amount of hard phases, i.e., martensite and bainite, respectively in the DP and TRIP steels. It was also found that the elongation also decreased with the amount of soft ferrite in the DP and TRIP steels and with the amount of the that was retained in the austenite phasein the TRIP steel, respectively for the DP and TRIP steels. For the Q&P steel, as the partitioning time increased, the elongation and the tensile strength increased slightly. This was due to the stabilized austenite that was enriched with carbon, even when the amount of retained austenite decreased as the partitioning time increased from 30 seconds to 100 seconds.

The Effects of gl, gh and wx Gene on the Grain Yield and Yield Components of Rice Plant (수도의 gl, gh 및 wx유전자가 수도수량 및 수량구성요소에 미치는 영향)

  • 김현구
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.22 no.1
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    • pp.83-109
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    • 1977
  • Isogenic lines for glabrous leaf (gl), hull color(gh) and glutinous endosperm (wx) were used to clarify the effects of the gl, gh and wx gene on the grain yield and yield components in rice plant. Eight genotypes: glgl ghgh wxwx, glgl ghgh WxWx, glgl GH-wxwx, glgl GH-WxWx, GL-ghgh wxwx, GL-ghgh WxWx, GL-GH-wxwx and GL-GH-WxWx were evalutated in the backcrossed $F_2$ generation. Significant effects were measured for gl genotypes on heading date, gh genotypes on grain fertility, and wxwx genotypes on number of panicles per hill and 1, 000 grain weight. The grain yield of straw hull and non glutinous lines were higher than gold hull and glutinous lines. The interaction of three genes, gl, gh and wx was significant for heading date, but not significant in other characters. The average value of isogenic lines which were combined with two recessive genes and one dominant gene were lower and the C.V. value was higher than the isogenic lines which were combined with two dominant genes and one recessive gene in all characters except plant height and number of grains per plant. The average value of isogenic line combined with three recessive genes was lower and the C.V. was higher than the isogenic line combined three dominant genes in all characters measured.

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Hydrogeochemistry of Some Abandoned Metal Mine Creeks in the Hwanggangri Mining District, Korea : A Preliminary Study (황강리 광화대에 분포하는 일부 폐금속 광산수계의 수리지구화학적 특성 : 예비연구)

  • 이현구;이찬희;이종창
    • Journal of the Korean Society of Groundwater Environment
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    • v.6 no.4
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    • pp.194-205
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    • 1999
  • Hydrogeochemical variation and environmental isotope at the some abandoned metal mine (Sanggok, Keumsil, Jangpung and Samdeok) creeks of the Hwanggangri mining district were carried out based upon the physicochemical properties for surface water collected of February in 1998. Hydrogeochemical composition of the all water samples are characterized by the relatively significant enrichment of Ca$^{2}$, alkaline ions, N $O_3$$^{-}$ and Cl$^{-}$ in normal surface water, whereas the surface waters near the mining area are relatively enriched in Ca$^{2+$, Mg$^{2+}$, heavy metals. HC $O_3$$^{-}$ and S $O_4$$^{2-}$. Surface waters of the mining creek have low pH, high EC and extremely high concentrations of TDS compared with surface water of the non-mining creeks. The range of $\delta$D and $\delta$$^{18}$O values (SMOW) in the waters are shown in -65.0 to-71.2$\textperthousand$ and -9.1 to-10.2$\textperthousand$. The d($\delta$D-$\delta$$^{18}$O) value with those of water samples ranged from 7.3 to 10.9. These $\delta$D and $\delta$$^{18/}$ of the acid mine water are more heavy values than those of surface water. The values have revealed the positive correlation between isotopic compositions and major elements, because those $\delta$D and $\delta$$^{18}$O values increase with increasing TDS. HC $O_3$$^{-}$ , S $O_4$$^{2-}$ and Ca$^{2+}$ concentration. Using WATEQ4F, saturation index of albite calcite, dolomite and mostly clay minerals in water of the mining area show undersaturated and progressively evolved toward the equilibrium condition due to fresh water mixing, however, surface waters of the non-mining area are nearly saturated and/or supersaturated. Geochemical modeling showed that mostly toxic heavy metals within water in the mining creek may exist largely in the from of metal-sulfate (MS $O_4$$^{2-}$), free metal (M$^{2+}$/), C $O_3$$^{-}$ and/or OH$^{-}$ complex ions. Based on the geology, water chemistry and environmental istopic data the water compositions from the Sanggok and Keumsil mine creek (consist mainly of Cambro-Ordovician carbonate rocks of the Cho-seon Supergroup) show higher PH, Ca$^{2+}$, Mg$^{2+}$ , HC $O_3$$^{-}$ and more heavy $\delta$D and $\delta$$^{18}$O values than those from the Jangpung and Samdeok mine creek (consist of age -unknown metasedimentary rocks of the Ogcheon Supergroup and/or Jurassic grani-toids), but each of these waters represents a similar hydrogeochemical evolution path by the mine water mixing.

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