• The Proceedings of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.5 no.2
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• pp.49-57
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• 1991

A simple system to measure the correlated color temperature ($T_c$) and color rendering index ($R_a$) oflight sources was developed. And the T, and R, of incandescent lamps (I/L) and various fluorescent lamps(F/L) were measured with varying source voltage and power frequency. As results, $T_c$ variations of I/L and F/L with varying source voltage were relatively large, but $R_a$, variations were small. And $T_c$, $R_a$, variations of F/L under 5OkHz of power frequency were small, but over 50kHz, it is supposed that $T_c$, and $R_a$, will vary significantly.

• Nutrition Research and Practice
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• v.18 no.2
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• pp.180-193
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• 2024

BACKGROUND/OBJECTIVES: Obesity is a major cause of metabolic disorders; to prevent obesity, research is ongoing to develop natural and safe ingredients with few adverse effects. In this study, we determined the anti-obesity effects of Rosa multiflora root extract (KWFD-H01) in 3T3-L1 adipocytes and Sprague-Dawley (SD) rats. MATERIALS/METHODS: The anti-obesity effects of KWFD-H01in 3T3-L1 adipocytes and SD rats were examined using various assays, including Oil Red O staining, gene expression analyses, protein expression analyses, and blood biochemical analyses. RESULTS: KWFD-H01 reduced intracellular lipid accumulation and inhibited the mRNA expression of peroxisome proliferator-activated receptor γ (PPARγ), cytidine-cytidine-adenosine-adenosine-thymidine (CCAAT)/enhancer binding proteins (C/EBPα), sterol regulatory element-binding transcription factor 1 (SREBP-1c), acetyl-CoA carboxylase (ACC), and fatty acid synthase (FAS) in 3T3-L1 cells. KWFD-H01 also reduced body weight, weight gain, and the levels of triglycerides, total and LDL-cholesterol, glucose, and leptin, while increasing high-density lipoprotein-cholesterol and adiponectin in SD rats. PPARγ, C/EBPα, SREBP-1c, ACC, and FAS protein expression was inhibited in the epididymal fat of SD rats. CONCLUSION: Overall, these results confirm the anti-obesity effects of KWFD-H01 in 3T3-L1 adipocytes and SD rats, indicating their potential as baseline data for developing functional health foods or pharmaceuticals to control obesity.

• Journal of the Chungcheong Mathematical Society
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• v.26 no.2
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• pp.323-342
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• 2013

Let $C[0,t]$ denote the function space of all real-valued continuous paths on $[0,t]$. Define $Xn:C[0,t]{\rightarrow}\mathbb{R}^{n+1}$ and $X_{n+1}:C[0,t]{\rightarrow}\mathbb{R}^{n+2}$ by $X_n(x)=(x(t_0),x(t_1),{\cdots},x(t_n))$ and $X_{n+1}(x)=(x(t_0),x(t_1),{\cdots},x(t_n),x(t_{n+1}))$, where $0=t_0$ < $t_1$ < ${\cdots}$ < $t_n$ < $t_{n+1}=t$. In the present paper, using simple formulas for the conditional expectations with the conditioning functions $X_n$ and $X_{n+1}$, we evaluate the $L_p(1{\leq}p{\leq}{\infty})$-analytic conditional Fourier-Feynman transforms and the conditional convolution products of the functions which have the form $${\int}_{L_2[0,t]}{{\exp}\{i(v,x)\}d{\sigma}(v)}{{\int}_{\mathbb{R}^r}}\;{\exp}\{i{\sum_{j=1}^{r}z_j(v_j,x)\}dp(z_1,{\cdots},z_r)$$ for $x{\in}C[0,t]$, where $\{v_1,{\cdots},v_r\}$ is an orthonormal subset of $L_2[0,t]$ and ${\sigma}$ and ${\rho}$ are the complex Borel measures of bounded variations on $L_2[0,t]$ and $\mathbb{R}^r$, respectively. We then investigate the inverse transforms of the function with their relationships and finally prove that the analytic conditional Fourier-Feynman transforms of the conditional convolution products for the functions, can be expressed in terms of the products of the conditional Fourier-Feynman transforms of each function.

• Journal of Korean Society on Water Environment
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• v.23 no.3
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• pp.324-331
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• 2007

This study was conducted to evaluate the influence of pollutant loads on the water quality in the Goseong reservoir from May 2005 to October 2006. Annual total runoff at the Goseong-cheon watershed was 968.0 mm in 2005, 382.6 mm in 2006, respectively. The mean concentration of BOD, COD and SS in the stream were 2.28, 6.03, 46.97 mg/L in rainy seasons and 0.95, 2.14, 6.05 mg/L in dry seasons at SWT C sub-watershed. Total-N concentrations ranged from 2.60 to 3.18 mg/L at SWT C sub-watershed, which was generally higher than the quality standard of agricultural water (1.0 mg/L). Total-P concentrations ranged from 0.044 to 0.130 mg/L at SWT C sub-watershed. Measured pollutant loads in the SWT C sub-watershed were 36.7 kg/day of BOD, 72.3 kg/day of T-N and 2.3 kg/day of T-P in 2005 at SWT C sub-watershed, 63.9 kg/day of BOD, 82.8 kg/day of T-N and 1.1 kg/day of T-P in 2006 at SWT C sub-watershed, respectively. In the analysis of the effluent characteristics for NPS pollutants, it appeared that the loading rates of effluent from SWT C watershed were, respectively, BOD 62.3%, T-N 69.6%, T-P 71.1%, SS 70.1% during the rainy season in 2006. The calculated T-N daily pollutant loadings by the unit loading factor method from each sub-watershed were much greater than observed, but the calculated T-P daily pollutant loadings much lesser than observed.

• Journal of ILASS-Korea
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• v.2 no.4
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• pp.47-53
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• 1997

By using a premixed laminar burner, the effect of mixture component on laminar burning velocity($S_L$) was investigated. The following was made clear ; (1)As the humidity$(H_2O)$, $CO_2$ and Ar in mixture is increased, $S_L$ decreased in proportion to quantity of those dilution gases. (2) The heat reaction theory says that mean thermal conductivity $(\lambda_m)$, specific heat $(C_{pm})$ of mixture and adiabatic flame temperatures $(T_b)$ affect $S_L$. As a result of theoretical analysis, the effect of $\lambda_m\;and\;C_{pm}$ on $S_L$ is less than 1/25 of the effect of $T_b$, so the effect of $\lambda_m\;and\;C_{pm}$ can be ignored. (3) From experimental results, it was confirmed that $\ln(S_L)$ is proportional to $(1/T_b)$, that is, the effect of $H_2O$ on $S_L$ is mainly caused by changes of $T_b$. This conclusion was verified by the fact increases of $H_2O,\;CO_2$ and Ar decrease the intensity of radiation typical $C_2$, CH, and OH in the same manner.

• Journal of the Korean Society of Food Science and Nutrition
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• v.29 no.2
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• pp.235-240
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• 2000

Inhibitory effects of cockle extracts on carcinogen-induced cytotoxicity in C3H/10T1/2 cells were studied. Soup (62$\mu\textrm{g}$/mL), solubility (28$\mu\textrm{g}$/mL) and liposolubility (9 $\mu\textrm{g}$/mL) of the cockle inhibited 3-methyl-cholanthrene(MCA)-induced cytotoxicity in C3H/10T1/2 cells by 53 and 94%, respectively. These results suggest that the extracts cockle might have anticarcinogen-induced cytotoxicity of C3H/10T1/2 cells. The effects of cockle extracts on the immune response related to its antitumor activity in vitro and in vivo were investigated. The cockle extracts showed a direct cytotoxic effect on sarcoma-180 cells, tumor cells in vitro. Soup (0.49 mg/mL), solubility (0.11 mg/mL) and liposolubiliy (0.05 mg/mL) of the cockle markedly decreased the total numbers of sarcoma-180 cells, but not their viability. The phagocytic acitivity of peritoneal macrophage of mice was significantly augmented by these extracts of the cockle compared with that of control in vivo. These extracts also raised the phagocuytic index, indicating that the number of phagocytize dmicrobes per macrophage increased. Thus, cockle extracts might show a antitumor activity by enhancing the phagocytic cell activities.

• 제어로봇시스템학회:학술대회논문집
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• 2003.10a
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• pp.2147-2150
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• 2003

Recently, many technologies of the P.L.C (Power Line Carrier) are introduced for an efficient communication. P.L.C communication sends information in the carrier signals by conduction over the power wire. An arc detector is proposed in this paper for the effective transmission. The Power Line Carrier has an advantage in low cost because it uses existent power line. It can be easily applied anywhere that a power line socket is available. But the P.L.C. is very noisy, because many electronic devices in generate electronic noise in modulated signals. This problem should be considered carefully in the design of the arc detector system using P.L.C in railway. The proposed system can be applied for monitoring the arc detector system and the arc locator system in railway. Hence the system will be able to exchange the arc information to be T.C.M.S. (Train Control Management System), bogies and even between a station and trains in railway and use to suspicion fire in train.

• Microbiology and Biotechnology Letters
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• v.33 no.4
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• pp.241-247
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• 2005

A new lactococcal shuttle/expression vector for lactococci, pWgal13T, was constructed using a $\beta$-galactosi-dase gene (lacZ) from Lacfococcus lactis ssp. lactis ATCC 7962 as a screening marker. The pWgal 13T was introduced into Escherichia coli DH5a and L. lactis MG1363, and was easily detected by the formation of blue colonies on a medium containing X-gal without any false transformants. Also, the quantitatively lacZ activity of pWgal13T was measured in L. lactis ssp. cremoris MG1363, and was found to be four times higher than that of L. lactis ssp. lactis ATCC7962 grown on a medium containing glucose, which shows that the lacZ gene of pWgal13T can be used for the efficient screening of L. lactis on general media. The pWgal13T was equipped with a lactococcal replicon of pWV01 from L. lactis Wg2, the new promoter P13C from L. lactis ssp. cremoris LM0230, multiple cloning sites, and a terminator for the expression of a relevant gene. The vee-tor pWgal13T was used for the expression of the EGFP gene in E. coli and L. lactis. These results show that the lactococcal expression/shuttle vector constructed in the present study can be used for the production of foreign proteins in E. coli and L. lactis.

• Journal of Life Science
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• v.28 no.6
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• pp.656-662
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• 2018

Flavin-containing monooxygenases from Corynebacterium (cFMOs) were mutagenized based on homology modeling to develop variants with an enhanced indigoid production capability. The four mutants, F170Y, A210G, A210S, and T326S, which fused to a maltose-binding protein (MBP), were constructed, and their biochemical properties were characterized. Of these, purified MBP-T326S required a higher concentration of exogenous FAD (100 mM) than the wild-type MBP-cFMO for optimal activity and showed a 3.8-fold increase in the $k_{cat}/K_m$ value at $100{\mu}M$ FAD compared to that of MBP-cFMO at $2{\mu}M$ FAD. The indole oxygenase activities of MBP-T326S decreased to 63-77% compared to that of the MBP-cFMO In addition, MBP-T326S displayed a very low level of futile NADPH oxidase activities (21-24%) in the absence of a substrate. Mutant proteins except for T326S displayed similar $K_m$ and increased $k_{cat}/K_m$ values compared to the wild-type. MBP-F170Y and -A210S mutants showed elevated indole oxygenase activity higher than 3.1- and 2.9-fold, respectively, in comparison with MBP-cFMO. When indigoid production was carried out in LB broth with 2.5 g/l of tryptophan, Escherichia coli expressing cFMO produced 684 mg/l of indigo and 104 mg/l of indirubin, while cells harboring T326S produced 1,040 mg/l of indigo and 112 mg/l of indirubin. The results indicate that the production of indigo was 13% higher when compared to a previous report in which an E. coli expressing FMO from Methylophaga produced 920 mg/l of indigo. The protein engineering of cFMO based on homology modeling provided a more rational strategy for developing indigoid-producing strains.

• Journal of Life Science
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• v.32 no.2
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• pp.86-93
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• 2022

Lupeol is a type of pentacyclic triterpene and has been reported to have pharmacological activities against various diseases; however, the effect of lupeol on glucose absorption has not been elucidated yet. This study aimed to investigate the effect of lupeol on glucose uptake in 3T3-L1 adipocytes. Lupeol significantly facilitated glucose uptake by translocating glucose transporter type 4 (GLUT4) to the plasma membrane of the 3T3-L1 adipocytes, which was related to activation of the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) and 5 'adenosine monophosphate-activated protein kinase (AMPK) pathways. In the PI3K/AKT pathway, lupeol stimulates the phosphorylation of insulin receptor substrate 1 (IRS-1), which activates PI3K. Its activation by lupeol promotes the phosphorylation of AKT, but not the atypical protein kinase C isoforms ζ and λ. Lupeol also promoted the phosphorylation of AMPK. The activation of AMPK increased the expressions of the plasma membrane GLUT4 and the intracellular glucose uptake. The increase in the glucose uptake by lupeol was suppressed by wortmannin (PI3K inhibitor) and compound C (AMPK inhibitor) in the 3T3-L1 adipocytes. The results indicate that lupeol can facilitate glucose uptake by increasing insulin sensitivity through the stimulation of the expression of plasma membrane glucose transporter type 4 via the PI3K/AKT and AMPK pathways in the 3T3-L1 adipocytes.