• Title/Summary/Keyword: Bypass Ratio

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Arabidopsis SIZ1 positively regulates alternative respiratory bypass pathways

  • Park, Bong-Soo;Kim, Sung-Il;Song, Jong-Tae;Seo, Hak-Soo
    • BMB Reports
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    • v.45 no.6
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    • pp.342-347
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    • 2012
  • Plant mitochondria possess alternative respiratory pathways mediated by the type II NAD(P)H dehydrogenases and alternative oxidases. Here, E3 SUMO ligase was shown to regulate alternative respiratory pathways and to participate in the maintenance of carbon and nitrogen balance in Arabidopsis. The transcript abundance of the type II NAD(P)H dehydrogenases NDA2 and NDB2 and alternative oxidases AOX1a and AOX1d genes was low in siz1-2 mutants compared to that in wild-type. The addition of nitrate or ammonium resulted in a decrease or an increase in the expression of the same gene families, respectively, in both wild-type and siz1-2 mutants. The amount of free sugar (glucose, fructose and sucrose) was lower in siz1-2 mutants than that in wild-type. These results indicate that low nitrate reductase activity due to the AtSIZ1 mutation is correlated with an overall decrease in alternative respiration and with a low carbohydrate content to maintain the carbon to nitrogen ratio in siz1-2 mutants.

Status and Characteristics of Unmanned Aerial Vehicle Gas Turbine Engines (무인 항공기 가스터빈 추진기관의 현황 및 특성 연구)

  • Joo, Milee;Choi, Seongman;Jo, Hana
    • Journal of the Korean Society of Propulsion Engineers
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    • v.24 no.2
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    • pp.61-72
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    • 2020
  • Performance characteristics of propulsion systems applied to UAVs that under development or completed in foreign countries were analyzed. In this study, aircraft mission and performance characteristics of ten UAVs were reviewed and compared with current available civil and military aircraft. Also performance characteristics of UAVs propulsion systems were summarized and engine design parameters were analyzed. Thrust, SFC and design parameters such as pressure ratio and bypass ratio of UAV propulsion system were compared with the current existing civil and military aircraft engines. From this study, the design parameters of the propulsion system applied to the UAV were well understood.

Non-invasive Evaluation of the Patients after Total Correction of Tetralogy of Fallot (활로 4 징증의 완전교정술후 비관혈적 방법에 의한 추적관찰)

  • 안홍남
    • Journal of Chest Surgery
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    • v.22 no.2
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    • pp.234-245
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    • 1989
  • Between January 1984 and December 1986, sixty nine patients, aged 16 months to 25 years [mean age 10.05*6.40 years], underwent total correction of tetralogy of Fallot in Kyungpook national university hospital. In 66 hospital survivors, 30 patients were followed up for 12 to 48 months [mean 30.10*10.26 months]. These 30 patients were classified in two groups, TAP [transannular patch] and Non-TAP group. There were 9 patients in TAP group, and 21 in Non-TAP group. There were no significant differences between two groups in terms of age at operation, follow up duration, ACC time, and bypass time. All patients were evaluated by two dimensional echocardiography, Doppler echocardiography, standard 12-lead electrocardiography, and plain chest X-ray. Right ventricular systolic pressure, pulmonary arterial systolic pressure, pressure gradient between the right ventricle and the pulmonary artery, presence or absence of pulmonary regurgitation and its grading, fractional shortening of the left ventricle, and Qp/Qs in case of remnant ventricular septal defect were obtained by echocardiographic examination. Cardiothoracic ratio was measured by plain chest film, and ventricular dysrrhythmia was detected by electrocardiogram. Comparing the data between two groups, there was significant difference in incidence of postoperative pulmonary regurgitation [p< 0.05], 100%[9/9] in TAP group and 47.6 %[10/21] in Non-TAP group, but all the regurgitations were not severe. There were no significant differences in other comparisons, despite of higher incidence of cardiomegaly in TAP group [CT ratio: 59.3*5.3% VS 54.7*6, 4 %].

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The Correlation between Cardiac Catheterization Data and Defect Size in Ventricular Septal Defect (심실중격결손증에서 술전 심도자검사치와 결손크기의 상관관계에 대한 연구)

  • 정상조
    • Journal of Chest Surgery
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    • v.23 no.3
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    • pp.430-437
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    • 1990
  • We clinically evaluated 121 cases of ventricular septal defect which we operated from April, 1986 to December, 1989 at Inha General Hospital, Seong-Nam, Department of Thoracic and Cardiovascular Surgery, College of Medicine, Inha University. These patients were occupied 54.8% of all congenital heart diseases operated on its same period. Of the 121 patients, 63 patients were male[52.1%] and 58 patients were female[47.9i]. The two most common symptoms were frequent upper respiratory infection and dyspnea on exertion. By Kirklin s anatomical classification, type I constituted 34.7%, type II 61.98%, type III 0.03% and type IV not occupied. Associated cardiac anomalies were found in 34 cases, and PDA was most common associated anomaly, occupied in 22 cases. On the cardiac catheterization data, there were statistically significant correlation between VSD size[cm2 /BSAm2] and systolic pulmonary arterial pressure[sPAP], pulmonary to systemic flow ratio[Qp/Qs] & pulmonary to systemic pressure ratio[Pp/Ps] respectively, Type II [r=0.53, p<0.01] was more correlated than type I [r=0.49, p<0.05] between VSD size and Qp /Qs. We could not found the correlationship between age and Qp/Qs [Type I; r=0.16, Type II; r=-0.15] All cases were operated under cardiopulmonary bypass and 58 cases[46.3%] were operated through the right atrial approach, and 34 cases[28.1%] through the pulmonary arterial approach. Operative mortality rate was 4.13%[5 cases].

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Effect of Feeding Bypass Protein with Urea Treated Grass on the Performance of Red Kandhari Calves

  • Wankhede, S.M.;Kalbande, V.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.7
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    • pp.970-973
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    • 2001
  • An experiment was carried out to assess the effect of feeding concentrate mixtures varying in bypass protein levels with urea-treated or untreated grass on the performance of twelve Red Kandhari calves (14 months of age and 78.15 kg body weight) for a period of 75 days. Dry grass was treated with 4 percent urea solution and ensiled for 30 days. The CP ($N{\times}6.25$) content in urea treated grass increased from 3.96 to 8.89 percent. Two iso-caloric and iso-nitrogenous concentrate mixtures (CM-I and CM-II) varying in RDP to UDP ratio viz., 65:35 and 55.45 were prepared. The calves in control group ($T_1$) were fed concentrate mixture-I with ad libitum untreated dry grass and those in experimental group ($T_2$) were fed concentrate mixture-II with ad libitum urea treated dry grass. The dry matter consumption in group $T_2$ was significantly (p<0.01) higher as compared to group $T_1$. The total DMI in $T_1$ and $T_2$ was 146.92 and 166.95 kg respectively, whereas the DMI per day and per 100 kg body weight was 1.94 and 2.22 and 1.90 and 2.35 kg, respectively. The average total gain in body weight (kg) and average daily gain (g) of calves in $T_2$ was significantly (p<0.01) higher as compared to those in $T_1$ the values being 28.66, 18.33 and 382.16, 244.44, respectively. Feed efficiency in terms of kg DM per kg gain in body weight was significantly (p<0.01) lower in group $T_1$ than in $T_2$. The cost of feed per kg gain in body weight for $T_2$ and $T_1$ group was Rs. 21.14, 28.22, respectively. The digestibility coefficients of DM, CP, EE, CF, NFE, NDF and ADF were 59.60, 57.50, 53.00, 65.04, 45.82, 48.48, 52.48 and 55.73 for $T_1$ group. The coressponding values were 68.78, 67.80, 59.83, 71.41, 49.93, 53.37 and 57.81, respectively for $T_2$ group. The digestibility coefficients for all the proximate principles in $T_2$ were significantly (p<0.01) higher as compared to $T_1$. However, NDF and ADF digestibilities were not significantly different. Nutritive value determined in terms of DCP and TDN for The experimental ration was significantly (p<0.01) higher than control ration, the values being 7.32 and 47.34 and 9.39 and 52.40% respectively. The blood urea nitrogen levels at 0, 3 and 6 h interval after feeding were significantly (p<0.01) lower in calves fed experiment ration as compared to control. The overall results indicated that in Red Kandhari calves an optimum growth can be economically achieved by feeding 4 percent urea treated dry and mature grass as basal roughage supplemented with a concentrate mixture containing 20 percent CP, 70% TDN and 45% UDP/bypass protein.

Engineering Characteristics of Blast Furnace Slag Cement Mortar Using Chlorine Bypass System-Dust as Alkali Activator (Chlorine Bypass System-Dust를 알칼리 자극제로 사용한 고로슬래그 시멘트 모르타르의 공학적 특성)

  • Han, Min-Cheol;Lee, Dong-Joo
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.8 no.2
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    • pp.235-244
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    • 2020
  • This study conducted a series of studies to offer a novel method of using CBS-dust that produced as by-product in the manufacture of cement. Four different contents of BS and CBS-dust were adopted for test parameters of this study. Mortar with 50% of W/B was fabricated. First, in the case of the fresh mortar, the flow decreased as the CBS-dust replacement rate increased, but the binder composition ratio BS 45% and 65% showed higher fl ow than Pl ain when repl acing CBS-dust 5%. In the case of air content, overall, the tendency was proportional to the CBS-dust replacement rate, and chloride tended to exceed the reference value at all replacement rates except for the CBS-dust 0% replacement. The compressive strength of the hardened mortar shows the resul t that the strength is improved when the CBS-dust is repl aced by 5% to 10%, and the CSH gel and structure formation is confirmed by microstructure analysis through the hydration reaction when the CBS-dust is replaced. Therefore, for a given condition CBS-dust is used as a early-strength admixture in a concrete secondary product that uses a large amount of admixture without reinforcing bars it can be an effective method for enhancing the strength of concrete as an alkali activator.

Use of radiotherapy in patients with palliative double bypass for locally advanced pancreatic adenocarcinoma

  • Glinka, Juan;Diaz, Federico;Alva, Augusto;Mazza, Oscar;Claria, Rodrigo Sanchez;Ardiles, Victoria;Santibanes, Eduardo de;Pekolj, Juan;Santibanes, Martin de
    • Radiation Oncology Journal
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    • v.36 no.3
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    • pp.210-217
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    • 2018
  • Purpose: Pancreatic cancer (PC) has not changed overall survival in recent years despite therapeutic efforts. Surgery with curative intent has shown the best long-term oncological results. However, 80%-85% of patients with these tumors are unresectable at the time of diagnosis. In those patients, first therapeutic attempts are minimally invasive or surgical procedures to alleviate symptoms. The addition of radiotherapy (RT) to standard chemotherapy, ergo chemoradiation, in patients with locally advanced pancreatic cancer (LAPC) is still controversial. The study aims to compare outcomes in patients with a double bypass surgery due to LAPC treated or not with RT. Materials and Methods: A retrospective cohort study of patients with double bypass for LAPC were registered and divided into two groups: treated or not with postoperative RT. Baseline characteristics, postoperative complications, those related to RT and their relation to the main event (mortality) were compared. Results: Seventy-four patients were included. Surgical complications between the groups did not offer significant differences. Complications related to RT were mostly mild, and 86% of patients completed the treatment. Overall survival at 1 and 2 years for patients in the exposed group was 64% and 35% vs. 50% and 28% in the non-exposed group, respectively (p = 0.11; power 72%; hazard ratio = 0.53; 95% confidence interval, 0.24-1.18). Conclusion: We observed a tendency for survival improvement in patients with postoperative RT. However, we've not had enough power to demonstrate this difference, possibly due to the small sample size. It is indispensable to develop randomized and prospective trials to guide more specific treatment lines in this patients.

Mid-Term Outcomes and Angiographic Patency of Redo Coronary Artery Bypass Grafting: A Comparison between OffPump and On-Pump Surgery

  • Sohn, Suk Ho;Kim, Seung Hyun;Hwang, Ho Young;Kim, Ki-Bong
    • Journal of Chest Surgery
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    • v.54 no.2
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    • pp.106-116
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    • 2021
  • Background: We evaluated the mid-term outcomes and angiographic patency of redo coronary artery bypass grafting (CABG). Methods: Of 2,851 patients who underwent isolated CABG at Seoul National University Hospital from 2000 to 2017, 88 underwent redo CABG. Patients' mean age at redo CABG was 66.0±8.0 years. The mean interval between the first-time and redo CABG was 113.0±62.4 months. The mean follow-up duration was 86 months. Early and mid-term clinical outcomes were evaluated. Angiographic patency rates were evaluated early (1-2 days), 1 year, and 5 years after surgery. Comparative analyses between on-pump and off-pump CABG were also performed. Results: The culprits for reoperation were previous grafts (65.6%), native coronary vessels (17.8%), and both (16.7%). Off-pump CABG was performed in 75 cases (85.2%), and the mean number of distal anastomoses was 1.8±0.8. The saphenous vein (39.7%) was used most frequently, followed by the right internal thoracic artery (28.4%), right gastroepiploic artery (21.3%), left internal thoracic artery (7.8%), and radial artery (2.8%). Operative mortality was 1.1%. The overall survival, cumulative incidence of cardiac death, and cumulative incidence of major adverse cardiac events were 71.3%,12.0%, and 23.3% at 5 years after surgery, respectively. The overall angiographic patency rates were 95.7%, 90.1%, and 92.2% on early, 1-year, and 5-year angiograms, respectively. The angiographic patency rates of saphenous vein grafts were 93.1%, 85.6%, and 91.3% on early, 1-year, and 5-year angiograms, respectively. No significant differences in clinical outcomes or angiographic patency rates were observed between the on-pump (n=13) versus off-pump (n=75) groups. Multivariable analysis revealed that age (hazard ratio [HR], 1.07; p=0.005) and chronic kidney disease (HR, 3.85; p=0.001) were risk factors for all-cause mortality. Conclusion: Redo CABG could mostly be performed using the off-pump technique and did not show increased operative mortality and morbidities.

The Impact of Ventilation Strategies on Indoor Air Pollution: A Comparative Study of HVAC Systems Using a Numerical Model (실내오염물질의 환기기술전략에 따른 영향평가 : 수치적 모델을 이용한 HVAC 시스템의 비교연구)

  • Park, Sung-Woo;Song, Dong-Woong;D.J. Moschandreas
    • Journal of Korean Society for Atmospheric Environment
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    • v.11 no.E
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    • pp.45-54
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    • 1995
  • Indoor air quality models are useful to predict indoor air pollutant concentrations as a function of several indoor factors. Indoor air quality model was developed to evaluate the pollutant removal efficiency of variable-air-volume/bypass filtration system (VAV/BPFS) compared with the conventional variable-air-volume (VAV) system. This model provides relative pollutant removal effectiveness of VAV/BPFS by concentration ratio between the conventional VAV system and VAV/BPFS. The predictions agree closely, from 5 to 10 percent, with the measured values for each energy load. As a results, we recommend the VAV/BPFS is a promising alternative to conventional VAV system because it is capable of reducing indoor air pollutant concentration and maintaining good indoor air quality.

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Type I Ventricular Septal Defect in Korean Pateints (한국인의 심실중격결손증 제 1형)

  • Lee, Yung-Kyoon;Yang, Gi-Min
    • Journal of Chest Surgery
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    • v.13 no.4
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    • pp.418-421
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    • 1980
  • During the period from August 1959 to end of July 1980, 69 cases of Type I VSD were noted among 235 cases of ventricular septal defect who were operated utilizing cardiopulmonary bypass in the Department of Cardio-thoracic Surgery, College of Medicine, Seoul National University(29.4%). During the same period 1162 open heart surgery cases were experienced among whom 778 cases were congenital anomalies. There were no significent differences between Type I '||'&'||' other tvpo:s of VSD in sex and age distribution. In Type I VSD frequency of aortic regurgitation association was much higher than rest of the types. (8.7% to 2.6%). Necessity of patch closure in Type I was not different from other types. The high incidence of Type I VSD is quite similar to Japanese references which show quite higher ratio compared with from Euroamerican caucasian patients materials. All cases were operated on with bubble type oxygenator mainly Shiley**" oxygenator utilizing hypothermic hemodilution perfusion technique.echnique.

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