• Tuberculosis and Respiratory Diseases
• /
• 제65권5호
• /
• pp.416-420
• /
• 2008

한약은 폐 질환을 일으키는 드문 원인이나 현재 동, 서양을 막론하고 한약의 사용 증가를 고려하면 향후 더 많은 경우에서 본 사례와 같은 한약 유발성 폐 질환을 경험할 것으로 생각된다. 보중익기탕으로 인한 간질성 폐렴은 국내에서 아직 보고된 바가 없고 이런 경우에서 가능성을 의심하고 초기에 진단하여 더 이상의 복용을 회피하고 적절하게 치료한다면 좋은 예후를 보일 것으로 예상된다. 이에 문헌 고찰과 함께 본 증례를 보고하는 바이다.

• 대한한의학회지
• /
• 제35권4호
• /
• pp.98-103
• /
• 2014

Objectives: Advanced malignant melanoma (MM) has a poor prognosis, with an expected 2-year survival rate of 10 to 20%. It has long been recognized as an immunogenic tumor, and is worse for elderly patients. Many studies have suggested that herbal treatments improve immune functions, but few clinical studies have reported on this topic. Patients and History: We present two cases of female patients (72 and 77 years old, respectively) with advanced MM. The 72-year-old female patient was, at first, diagnosed with MM with multiple bone metastases. She received resection of the primary lesion, but refused further chemotherapy. The 77-year-old female patient was diagnosed with cutaneous MM of the left heel, with suspicion of sentinel node lymphadenopathy; however, she also refused any conventional treatment due to old age. Course of Therapy and Results: Both patients were exclusively treated with standardized allergen-removed Rhus verniciflua stokes (aRVS) extract combined with Bojungikki-tang (BT, Bu-Zhong-Yi-Qi-Tang in Chinese or Hochu-ekki-to in Japanese). Both patients are still alive and doing well (Feb. 2014), demonstrating that the 72-year-old patient has lived for 27 months and the 77-year-old patient has lived for 31 months without disease progression since the aRVS and BT administration. Conclusion: We suggest that the combination of aRVS extract and BT could be a candidate for overcoming the cancer's immunoediting process especially for elderly MM patients intolerant of conventional treatment.