• Advances in Traditional Medicine
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• v.7 no.3
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• pp.280-285
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• 2007

The methanol extract of leaves of Bruguiera gymnorrhiza (L.) Lam. (Rhizophoraceae) was screened for its antinociceptive and antidiarrhoeal activities. The extract produced significant inhibition in acetic acid-induced writhing in mice at dose of 250 and 500 mg/kg body weight (P < 0.001), comparable to the standard drug diclofenac sodium at the dose of 25 mg/kg of body weight (P < 0.001). When tested for its antidiarrhoeal effects on castor oil-induced diarrhea in mice, it increased mean latent period (P < 0.02) and decreased the frequency of defecation (P < 0.01) significantly at the dose of 500 mg/kg body weight, comparable to the standard drug loperamide at the dose of 50 mg/kg of body weight. The overall results tend to suggest the antinociceptive and antidiarrhoeal activities of the extract.

• Journal of Marine Bioscience and Biotechnology
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• v.1 no.1
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• pp.22-33
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• 2006

This paper deals mainly with chemical and biological investigations, recently effected in the authors' laboratory, of Chinese tropical marine plants and invertebrates on three topics: 1) an unusual macrocyclic polydisulfide from the Chinese mangrove Bruguiera gymnorrhiza; 2) polyhydroxylpolyene compounds from marine dinoflagellate Amphidinium sp.; 3) two new series of uncommon steroids from marine in vertebrates.