• 제목/요약/키워드: Brown line

검색결과 393건 처리시간 0.032초

섬진강에 서식하는 멸종위기어류 모래주사 Microphysogobio koreensis(Pisces: Gobioninae)의 산란특성 (Spawning Characteristics of an Endangered Freshwater Fish Microphysogobio koreensis (Pisces: Gobioninae) in the Semjingang (river) from Korea)

  • 박종성;김형수;박종영
    • 한국어류학회지
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    • 제29권4호
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    • pp.261-266
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    • 2017
  • 모래주사 Microphsygobio koreensis는 환경부에 의해 멸종 위기종으로 보호받고 있는 한국 고유종이다. 본 연구에서 모래주사의 산란시기와 특성에 대한 조사를 통해 종 보존을 위한 기초자료를 얻고자 하였다. 조사는 2011년 4월부터 2012년 10월까지 전북 임실군 신평면 덕암리에서 실시하였다. 자연 상태와 조직학적 관찰을 통해 산란시기는 4~5월로 산란 성기는 수온이 $20{\sim}23^{\circ}C$인 5월초로 확인되었다. 산란시기의 수컷은 몸 전체가 밝은 주황색을 띄고 아가미 뒷부분에서부터 미병부까지 이어지는 중앙 줄무늬와 가슴지느러미 그리고 배지느러미가 붉어지는 특징을 보였고 추성은 나타나지 않았다. 반면 암컷은 몸 전체가 어두운 갈색을 가졌다. 난소 내 포란수는 10,705~22,165 ($15,573{\pm}4,274$)개였고 성숙난의 수는 1,100~5,920 ($3,383{\pm}2,126$)개로 나타났으며 성숙난의 비율은 10.3~44.8 ($22.4{\pm}15.6$)%였다. 그리고 성숙난의 크기는 $0.74{\pm}0.06$ (0.60~1.00) mm였다.

칡소의 MC1R의 유전자형에 따른 교배 조합이 자손의 모색과 유전자형 변이에 미치는 영향 (Effects of Genotype Mutation and Coat Color Phenotype on the Offspring from Mating System of MC1R Genotype Patterns in Korean Brindle Cattle)

  • 김상환;정경섭;이호준;백준석;정덕원;김대은;윤종택
    • 한국수정란이식학회지
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    • 제28권3호
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    • pp.215-222
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    • 2013
  • Bovine coat color is decided by the melanocortin receptor 1 (MC1R) genotype mutation and melanogenesis. Specially, in the various cattle breeds, dominant black coat color is expressed by dominant genotype of $E^D$, red or brown is expressed in the frame shift mutation of recessive homozygous e by base pair deletion and wild type of $E^+$ is expressed in various coat colors. However, not very well known about the effected of MC1R genotype mutation on the coat color through family lines in KBC. Therefore, this study were to investigate effect of MC1R genotype mutation on the coat color, and to suggest mating breed system in accordance with of MC1R genotype for increased on brindle coat color appearance. Parents (sire 2 heads and dam 3 heads) and offspring (total : 54 heads) from crossbreeding in KBC family line with the MC1R genotype and phenotype records were selected as experimental animals. The relationship between melanocortin 1 receptor (MC1R) genotypes expression verified by PCR-RFLP, and brindle coat color appearance to the family line of the cross mating breed from MC1R genotype pattern was determined. As a result, 4MC1R genetic variations, $E^+/E^+$ (sire 1), $E^+/e$ (sire 2 and dam 3), $E^+/e$ with 4 bands of 174, 207 and 328 bp (dam 1) and $E^+/e$ with 3 bands of 174, 207, 328 and 535 bp (dam 2) from parents (sire and dam) of KBC. However, 3 genetic variations, e/e (24%), $E^+/E^+$ (22%) and $E^+/e$ (56%) were identified in offspring. Also, brindle coat color expressrated was the e/e with the 0%, $E^+/E^+$ with 67% and $E^+/e$ with 77% from MC1R genotype in offspring on the cross mating of KBC. Furthermore, when the sire had $E^+/e$ genotype and the dam had $E^+/E^+$ with the 3 bands or $E^+/e$ genotype, and both had whole body-brindle coat color, 62% of the offspring had whole body-brindle coat color. Therefore, the seresults, the mating system from MC1R genotype patterns of the sires ($E^+/e$) and dams ($E^+/E^+$ with the 3 bands or $E^+/e$) with brindle coat color may have the highest whole body-brindle coat color expression in their offspring.

삼봉탄광 주변 수계에 대한 지화학적 특성 및 침전물에 대한 광물학적 연구 (Mineralogy of Precipitates and Geochemisty of Stream Receiving Mine Water in the Sambong Coal Mine)

  • 우엄식;김영훈;김정진
    • 한국광물학회지
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    • 제29권4호
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    • pp.199-207
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    • 2016
  • 폐 석탄광산에서 가장 큰 환경문제는 산성광산배수가 유출되어 주변 하천수의 pH를 낮추고 철/알루미늄 수산화물을 하천바닥에 침전시키며 주변 토양을 오염시키는 것이다. 삼봉광산에서 물시료와 침전물 시료는 갱구 입구에서 채취하였다. 채취한 갱내수의 pH 값의 범위는 겨울에 7.24-7.94이며, 여름에 3.87-5.73이다. 전기전도도는 갱내수가 유입되는 하천에서 $432-897{\mu}S/cm$이다. 갱내수의 Mg, Al, Ca, Mn의 최고 농도값은 각각 15.50, 4.56, 85.30, 12.76 mg/L이다. 적갈색의 침전물은 겨울에는 Munsell color 10R-5YR 정도로 주구성광물은 2-line 페리하이드라이트이며, 여름에는 2.5YR-5Y의 범위로 주구성광물은 슈워트마나이트이다. 주사전자현미경 관찰 결과 침전물은 막대형 혹은 원통형이거나, $0.1-0.5{\mu}m$의 구균형이나 구형을 나타내고 있다.

Prognostic Factor Analysis of Overall Survival in Gastric Cancer from Two Phase III Studies of Second-line Ramucirumab (REGARD and RAINBOW) Using Pooled Patient Data

  • Fuchs, Charles S.;Muro, Kei;Tomasek, Jiri;Van Cutsem, Eric;Cho, Jae Yong;Oh, Sang-Cheul;Safran, Howard;Bodoky, Gyorgy;Chau, Ian;Shimada, Yasuhiro;Al-Batran, Salah-Eddin;Passalacqua, Rodolfo;Ohtsu, Atsushi;Emig, Michael;Ferry, David;Chandrawansa, Kumari;Hsu, Yanzhi;Sashegyi, Andreas;Liepa, Astra M.;Wilke, Hansjochen
    • Journal of Gastric Cancer
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    • 제17권2호
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    • pp.132-144
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    • 2017
  • Purpose: To identify baseline prognostic factors for survival in patients with disease progression, during or after chemotherapy for the treatment of advanced gastric or gastroesophageal junction (GEJ) cancer. Materials and Methods: We pooled data from patients randomized between 2009 and 2012 in 2 phase III, global double-blind studies of ramucirumab for the treatment of advanced gastric or GEJ adenocarcinoma following disease progression on first-line platinum- and/or fluoropyrimidine-containing therapy (REGARD and RAINBOW). Forty-one key baseline clinical and laboratory factors common in both studies were examined. Model building started with covariate screening using univariate Cox models (significance level=0.05). A stepwise multivariable Cox model identified the final prognostic factors (entry+exit significance level=0.01). Cox models were stratified by treatment and geographic region. The process was repeated to identify baseline prognostic quality of life (QoL) parameters. Results: Of 1,020 randomized patients, 953 (93%) patients without any missing covariates were included in the analysis. We identified 12 independent prognostic factors of poor survival: 1) peritoneal metastases; 2) Eastern Cooperative Oncology Group (ECOG) performance score 1; 3) the presence of a primary tumor; 4) time to progression since prior therapy <6 months; 5) poor/unknown tumor differentiation; abnormally low blood levels of 6) albumin, 7) sodium, and/or 8) lymphocytes; and abnormally high blood levels of 9) neutrophils, 10) aspartate aminotransferase (AST), 11) alkaline phosphatase (ALP), and/or 12) lactate dehydrogenase (LDH). Factors were used to devise a 4-tier prognostic index (median overall survival [OS] by risk [months]: high=3.4, moderate=6.4, medium=9.9, and low=14.5; Harrell's C-index=0.66; 95% confidence interval [CI], 0.64-0.68). Addition of QoL to the model identified patient-reported appetite loss as an independent prognostic factor. Conclusions: The identified prognostic factors and the reported prognostic index may help clinical decision-making, patient stratification, and planning of future clinical studies.

팽이버섯의 저장기간 및 품종별 자실체내의 당 함량 변화 (Changes of saccharide content in fruitbody composition of Flammulina velutipes during storage)

  • 전창성;윤형식;임훈태;공원식;이강효;성기호;조재한
    • 한국버섯학회지
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    • 제9권3호
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    • pp.123-131
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    • 2011
  • 최근 수요가 많은 식용버섯 중 팽이버섯을 대상으로 저장기간 중에 발생하는 자실체 내의 당 종류 및 함량변화를 검토하고자 시험을 수행하였다. 팽이버섯 자실체에는 단당류로는 xylose 및 glucose, ribose, 이당류의 당은 lactose 및 trehalose, 당알코홀류는 glycerol 및 mannitol, myoinositol, sorbitol 등이 확인되었다. 팽이버섯에 가장 많은 것은 단당류인 xylose로 백색계열은 47.68mg/g, 갈색계열은 63.28mg/g로 갈색계열의 함량이 높으며, 품종에 따라 약간의 차이를 보였다. 저장기간에 따른 당 함량은 단당류 및 이당류, 당알코올 모두 저장 시간이 증가하면서 같이 증가하는 추세를 보이고 있으나, trehalose는 감소하였다. 저장온도에 따라서는 큰 차이는 없었으나, lactose는 $4^{\circ}C$ 저장에서 저장기간이 길어질수록 크게 증가하는 것으로 나타났으나, $-1^{\circ}C$ 저장에서는 검출되지 않았다.

원자로심의 열적여유도 증대를 위한CETOP-D의 입구유량인자 최적화 기법 개발 (Development of an Optimization Technique of CETOP-D Inlet Flow Factor for Reactor Core Thermal Margin Improvement)

  • Hong, Sung-Deok;Lim, Jong-Seon;Yoo, Yeon-Jong;Kwon, Jung-Tack;Park, Jong-Ryul
    • Nuclear Engineering and Technology
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    • 제27권4호
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    • pp.562-570
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    • 1995
  • 근래의 ABB/CE형 가압경수로들은, 정상운전 및 예상운전과도상태 중에 허용핵연료설계제한치가 위배되는 것을 방지하기 위하여, 노심 운전상태를 감시하는 디지탈노심감시계통, COLSS(Core Oper-ating Limit Supervisory System)를 보유하고있다. COLSS의 주요 기능 중 하나는. 측정되는 운전조건에 대한 최소 핵비등이탈률을 계산하여, 핵비등이탈에 대한 과출력여유도를 감시하는 것이다. COL-SS에서 최소 핵비등이탈률을 계산하는데 사용되는 CETOP-D 모델은 상세부수로분석코드인 TORC 모델에 대해 보수적으로 벤치마킹되며, 보정상수로서 고온집 합체의 입구유량인자를 사용하고 있다. 본 연구에서는 CETOP-D 입구유량인자를 가장 제한적인 운전조건에서 보수적인 단일 값으로 결정하는 ABB/CE 방법을 배제하고, 운전조건에 따른 CETOP-D 입구유량인자 변화를 상관식형태로 결정하는 “CETOP-D 입구유량인자 최적화기법”을 개발하였다. 개발된 방법을 영광 3,4호기 초기노심의 노심운전영역에 적용한 결과, 기존의 ABB/CE 방법에 비하여 정상운전영역에서 핵비등이탈에 대한 과출력여유도가 2% 가량 증가하였다.

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종간교잡 신품종 주황색 비모란 '여명' (A New Gymnocalycium × hyrida 'Yeomyeong' with Orange Color)

  • 정명일;정봉남;박필만
    • 화훼연구
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    • 제17권4호
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    • pp.320-323
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    • 2009
  • 주황색 접목선인장 '여명'은 G. marsoneri 와 G. mihanovichu 간의 종간교잡품종으로 2005년 농촌진흥청 국립원예특작과학원에서 육성되었다. 1999년 G. marsoneri ${\times}$ G. mihanovichii 'IG-112'를 교배하여 2001년 주황색 종간교잡종 '9922012' 계통을 선발하였다. '9922012' 계통을 모본으로 G. mihanovichii 'IG-l77'을 부본으로 교배하여 2002년 주황색 계통들을 선발하였다. 선발된 계통을 대상으로 2003년부터 3년간 3차의 특성검정 후 주황색 '원교G1-159'을 육성하였다. '원교G1-159'은 2005년 농촌진흥청 직무육성 신품종 선정위원회에서 '여명'으로 명명되었다. '여명'은 구색이 모구와 지구가 주황색이다. 구의 모양은 편원형으로 7~9개의 결각을 가졌으며, 가시는 회갈색으로 길이가 짧고 직립한다. 정식 10개월 후에 직경이 41.8~47.7 mm로 대비품종에 비하여 생육이 빠르고, 지구수도 6.9~12개로 많았다. 여명'은 미국과 네덜란드 수출용으로 선발되었으며 품종의 특성은 영양번식에 의하여 유지된다.

Dynamic of heat production partitioning in rooster by indirect calorimetry

  • Rony Lizana, Riveros;Rosiane, de Sousa Camargos;Marcos, Macari;Matheus, de Paula Reis;Bruno Balbino, Leme;Nilva Kazue, Sakomura
    • Animal Bioscience
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    • 제36권1호
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    • pp.75-83
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    • 2023
  • Objective: The objective of this study was to describe a methodological procedure to quantify the heat production (HP) partitioning in basal metabolism or fasting heat production (FHP), heat production due to physical activity (HPA), and the thermic effect of feeding (TEF) in roosters. Methods: Eighteen 54-wk-old Hy Line Brown roosters (2.916±0.15 kg) were allocated in an open-circuit chamber of respirometry for O2 consumption (VO2), CO2 production (VCO2), and physical activity (PA) measurements, under environmental comfort conditions, following the protocol: adaptation (3 d), ad libitum feeding (1 d), and fasting conditions (1 d). The Brouwer equation was used to calculate the HP from VO2 and VCO2. The plateau-FHP (parameter L) was estimated through the broken line model: HP = U×(R-t)×I+L; I = 1 if t<R or I = 0 if t>R; Where the broken-point (R) was assigned as the time (t) that defined the difference between a short and long fasting period, I is conditional, and U is the decreasing rate after the feed was withdrawn. The HP components description was characterized by three events: ad libitum feeding and short and long fasting periods. Linear regression was adjusted between physical activity (PA) and HP to determine the HPA and to estimate the standardized FHP (st-FHP) as the intercept of PA = 0. Results: The time when plateau-FHP was reached at 11.7 h after withdrawal feed, with a mean value of 386 kJ/kg0.75/d, differing in 32 kJ from st-FHP (354 kJ/kg0.75/d). The slope of HP per unit of PA was 4.52 kJ/mV. The total HP in roosters partitioned into the st-FHP, termal effect of feeding (TEF), and HPA was 56.6%, 25.7%, and 17.7%, respectively. Conclusion: The FHP represents the largest fraction of energy expenditure in roosters, followed by the TEF. Furthermore, the PA increased the variation of HP measurements.

산난계의 유전적 모수 추정과 조기선발효율에 관한 연구 (Study on the Estimation of Genetic Parameters and Selection Efficiency on Early Part-record for Improving Egg Production in Layer)

  • 이득환;오봉국
    • 한국가금학회지
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    • 제15권3호
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    • pp.211-218
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    • 1988
  • 산난종계의 주요 경제형질인 산난양의 개량은 단기검정에 의한 조기선발이 실용화되고 있는 바 산난수에 대하여 조기선발 하였을 경우 조기선발의 최적시기 및 조기선발에서 기대되는 상관적 선발효율을 알아본 결과는 다음과 같다. 1. 2계통의 일반능력을 조사란 평균치는 초산일령에서 150.5 일과 159.1 일이었고 조기산란수는 W계통에서 후기산란수는 B계통에서 더 많이 산란하였고 총산란수는 두 계통 모두 272개로 비슷하게 산란하였다. 2. 초산일령과 산란수에 대한 유전력 및 표준오차 추정치는 두 계통에서 전자매분산성분으로 추정하였을 때 $0.37\pm0.09$~$0.49\pm0.10$$0.18\pm0.10$x~$0.33\pm0.08$로 추정되었다. 특히 산란수에 대한 추정치는 W계통은 모분산성분에 의한 추정치가, B계통에서는 부분산성분에 의한 추정치가 더 높았고 두 계통 모두 후기산란수에 대한 유전력보다 조기산란수에 대한 유전력이 더 높게 추정되었다. 3. 각 조사형질들 간의 유전상관 및 표준오차의 추정결과는 W와 B계통에서 전자매공분산성분에 의하여 추정하였을 때 조기산란수와의 유전상관에 있어서 후기산란수는 $0.46\pm0.15$$0.39\pm0.16$, 총산란수는 $0.77\pm0.07$$0.76\pm0.08$ 초산일령은 -$0.77\pm0.06$$-0.82\pm0.05$이었고 후기산란수와는 총산란수는 $0.92\pm0.03$$0.89\pm0.04$로 비교적 높게 추정되었으며 초산일영령 $-0.11\pm0.17$$-0.15\pm0.18$로 미약한 원의 상관을 보였다. 총산란수와 초산일령과의 유전상관은 W계통에서 $-0.41\pm0.13$과 B계통에서 -$0.50\pm$0.13으로 모두 원의 상관을 보여 산란수에 준한 선발은 초산일영을 단축시킨다는 것을 추측할 수 있다. 4. 선발효율의 추정결과는 초산 시부터 40주령까지의 산란수에 의하여 선발하는 것이 가장 효율적인 것으로 추정되었으나 (1.69와 1.80) 이 시기의 산란수에 의하여 선발하였을 경우 초산일령과의 견전상관을 고려할 때 초산일영을 크게 단축시킬 것으로 사료되며 또한 초산일령의 단축으로 인한 난중의 감소 및 자료수집에 필요한 경비 등을 고려할 때 31주령 이후, 특히 31주령부터 40주령까지의 산란기녹에 의하여 선발하는 것이 바람직 할 것으로 사료된다.

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미국(美國) 내셔널브랜드 C사(社)의 마케팅전략(戰略)을 통한 브랜드리뉴얼 성공사례(成功事例) 연구(硏究) (A Study on the Successful Case of Brand Renewal through American National Brand 'C' Company's Marketing Strategy)

  • 고희숙
    • 패션비즈니스
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    • 제6권1호
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    • pp.137-154
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    • 2002
  • It's not easy to renew old brand of over 50 years history to the tastes of new consumer of our time. Most of national brands that has a history of some 20 years in Korea have strove for continuation and growth of brand to no avails, which can be taken as a good example of current situation. For instance, C company, one of the National brand of US which has a history of 51 years, has made its position secure as a fashion group and based itself on a sound foundation by establishing new marketing strategy and completing successful brand renewal in the process of strategic M&A with Italian company. Those successful marketing strategies are as follows. 1) they regarded both market and consumer oriented marketing activity as company's highest priority strategy and put great emphasis upon concentration on target market and reestablishment of brand image of business casual wear. 2) Setting up and operating planning team composed of merchandizer alone in Milano, they set the direction of plan on the basis of concentrated research on potential item in market according to thorough market research done by buying office in Korea, branch office in Hong Kong and buyer in US prior to blueprint planning for season. 3) Great emphasis was placed on business which focused on intensive presentation of basic key item for apparel career women who are main consumer group in the midium-low prices market in US and on supplementation of size and color. they named this line 'collectibles' and helped their customer develop their own clothes plan without worrying about the change of color and fabric by supporting same fabric and color throughout the year and enabled them to add variation easily by supplementing new trend item. 4) Company set black as a main color that lots of apparel career women find easy to care and to express their own image and presented them with pebble which belongs to navy and beige and added fashion color such as wine and brown etc as season goes by. They constructed basic line in order for their customers to coordinate purchased item with new one or to add them to present collection, and to achieve efficient sale by setting up strategy which allows this cross coordination and changing pattern occasionally. 5) Though basic jacket for 99$, short slim skirt for 49$ are products within midium-low prices range, in the material planning stage aiming at production of item that has both resonable function appealing to consumer and is fashionable, synthetic material had to be used as a main source due to price competitiveness. Despite this situation, considering comfortable sense of fit and refined drape of silhouette that has no sign of cheap material, whole collectible line was divided into two items, which contributed to reduction of cost. In case of material that is composed of triacetate and polyester in 70 to 30 ratio, was used up to 4 million yard, which allowed drastic curtailment of cost accompanied by concentration. In case of 'collectibles' line, using Korean material mainly, C company chose to have their product sewed in Southeast Asian countries where transportation is well developed and both productivity and quality verified by operating global production system which aiming at cutdown of cost through outsourcing production from the country where labor cost is low and getting finished product. Polarization between present consumers telling us that consumers with the mind of middle classes in the past no longer exists between consumers who seek after only fine article of highest quality and wise consumers who are sensible enough to judge bubble on correlation between price and quality. To cope with this change in new consumer mind, apparel makes changing their policy so as to produce item that has reasonable quality and falls within affordable price range anywhere in the world. and they're striving to get out of difficult situation by operating global marketing strategy which stresses separation of planning, production and sale and sensibility of fashion shared worldwide. The marketing strategy of C company can be exemplified as a successful one.