• Bulletin of the Korean Chemical Society
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• 제12권2호
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• pp.214-219
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• 1991

To study the effect of solvents and counterions in Z-DNA crystal of d(5BrC-G-5BrC-G-5BrC-G), we performed the local energy analysis and then molecular dynamics simulations. Since counterions raise serious caging problems in crystal simulations, it is very important to search for the possible positions before simulations. For this purpose, the local energy analysis was done for the whole crystal volume. It is shown from our simulation that counterions along with water molecules play a bridging role to bind adjacent oligomers so as to form the crystal. In this crystal, each water molecule bound to Gua-N2H, either directly or indirectly, hydrates the adjacent anionic phosphate oxygen, and thus assists Gua to be in a syn position. From the simulation, the average root-mean-square deviation of allthe DNA heavy atom coordinates from the X-ray data is $0.99{\AA}$ . The bases are less deviated from the X-ray positions than the phosphates. The temperature factors from the simulation are consistent with those from the X-ray refinement, showing that the phosphates are more mobile than the bases.

• 한국결정성장학회지
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• 제33권1호
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• pp.7-14
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• 2023

유리병 제조 공장에서 생산한 유리 조성을 4년간 40 차례 분석하여 Lakatos 모델로 점도를 구하였다. log η가 3, 6.6, 10, 12.3 Pa·s 일 경우의 isokom 온도를 구하여 조성과 isokom 온도와의 상관관계를 분석하였다. 조성에서 함량에 편차가 가장 큰 것은 MgO로 변동계수가 0.890이었다. 그러나 MgO 함량 편차가 점도 변화에 주는 영향은 제한적 이었다. 반면 CaO는 연화점 이하에서 비가교산소를 감소시키는 작용에 의하여 isokom 온도를 낮추고 있었다.

• 패션비즈니스
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• 제27권2호
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• pp.1-25
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• 2023

Taq-i Bustan rock reliefs are relatively well preserved among Sassanid relics. They are considered concrete and empirically important materials for studying Sassanian culture. In these rock reliefs, inauguration of various kings and hunting scenes are depicted. Thus, kings' attire and life of the court could be discerned according to eras. The purpose of this study was to investigate Sassanian clothing styles of various social positions by analyzing their clothing depicted in rock reliefs and to improve comprehension of the culture of the Sassanian Dynasty. Methodically, literature studies and artifacts were analyzed in parallel. Data of these two insources were consolidated for comparison. Results of this study are as follows. Since the Sassanian Dynasty succeeded the Parthian Dynasty, the Parthian style of clothing pieces such as tunic and trousers appeared in their attire. Basic types of tunics and trousers did not vary according to social status or age. However, details showed differences in those aspects. In the early Sassanian Dynasty, the dressing style of Rome was adopted. Styles of tunic and trousers featured draperies with many wrinkles and shoes were worn instead of boots. Trousers were tied with laces at ankles and laces were decorated with round clasps, imitating the style used by Kushan kings to the east of Sasanians. External cultural elements were also present in costumes of the Sassanian Dynasty, which played a bridging role for cultural exchanges between Eastern and Western civilizations at the gateway of the Silk Road.

• 농촌계획
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• 제28권1호
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• pp.49-55
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• 2022

School closures in rural areas is especially relevant because low fertility rate and population aging are common not only in rural but also in urban areas. This paper examined a variety of users' perceptions on welfare facilities using closed rural schools. For this study, the descriptive survey research design was conducted at the EZER located in Kyungsnangbuk-do. The sample size of 200 was selected through convenience sampling and data collection was completed by a self-completion written questionnaires. Main findings are as follows: 1) the level of users' relative satisfaction with welfare facilities using closed rural schools was generally positive, main factor associated with relative satisfaction was facilities and surrounding environment at closed rural schools, 2) socioeconomic usefulness of closed rural schools was also was generally positive, main factors for revitalization were adequate facilities and places, accessible and convenient places, 3) future necessity and willingness for welfare facilities using closed rural schools were overwhelmingly positive, children or youth were revealed as a priority service target. Finally, theses analyses show that a high proportion in the rural welfare sector, especially seemed to have a positive impact on bridging negative gabs between urban and rural in the socioeconomic development and social welfare.

• 산경연구논집
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• 제14권1호
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• pp.39-47
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• 2023

Purpose: This research aims at determining institutional commitment impact and how it influences job satisfaction. It aims at bridging the gap in research on the study topic. Its major focus is on work content and institutional commitment as the main variables and how they impact companies and employees. Research design, data and methodology: The current research has chosen the literature content approach and it is a reporting guideline for methodical assessments. It offers a consistent approach for conducting and reporting these types of studies, which can help to improve the quality and transparency. Results: The finding of the current research has showed that workers in social companies need jobs with higher values and responsibilities, company policy, among other factors. Workers' organization commitment towards social enterprise for improving workers' job satisfaction factors will include affective commitment, continuous commitment, normative commitment, and the commitment profile of the organization. Conclusions: This research finally insists that the findings of the current research would aid in enhancing employee knowledge and understanding of work satisfaction, as well as the essence of institutional commitment. Most employees lack adequate knowledge of the implications of job satisfaction not forgetting their personal needs as indicated in the individual need model.

• Asian Journal of Innovation and Policy
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• 제12권3호
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• pp.363-382
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• 2023

This study aims to discern the determinants influencing the perception of workability among the elderly population and delineate an appropriate retirement age within the labor market context. Employing binary logistic regression, this research utilizes data from the Korea Welfare Panel Study (2008, 2012, 2016, and 2020) provided by the Korea Institute for Health and Social Welfare. The findings indicate that key factors shaping the elderly's perception of workability encompass familial responsibilities (household and marital status) and their levels of physical and mental well-being. Econometric analysis suggests an anticipated retirement age for the elderly population ranging between 67 and 69 years. In addressing labor market demands and informing policymakers, the study proposes deliberations on extending the retirement age for individuals aged 60 to 65. This range serves as a compromise between the identified retirement age of 67 to 69 and the current average retirement age for elderly labor market participants. Bridging the disparity between the perceived workability age and the prevailing labor market baseline is crucial for achieving social consensus. Therefore, any extension of the retirement age should carefully consider both the demand and supply perspectives within the labor market. The study's contribution lies in two main aspects: firstly, presenting a retirement age framework for the labor market that integrates the workability of the elderly population, and secondly, providing evidence-based research outcomes to guide informed labor policies.

• Korean Journal of Radiology
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• 제25권5호
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• pp.459-472
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• 2024

Hyperpolarized (HP) carbon-13 (¹³C) MRI represents an innovative approach for noninvasive, real-time assessment of dynamic metabolic flux, with potential integration into routine clinical MRI. The use of [1-¹³C]pyruvate as a probe and its conversion to [1-¹³C]lactate constitute an extensively explored metabolic pathway. This review comprehensively outlines the establishment of HP ¹³C-MRI, covering multidisciplinary team collaboration, hardware prerequisites, probe preparation, hyperpolarization techniques, imaging acquisition, and data analysis. This article discusses the clinical applications of HP ¹³C-MRI across various anatomical domains, including the brain, heart, skeletal muscle, breast, liver, kidney, pancreas, and prostate. Each section highlights the specific applications and findings pertinent to these regions, emphasizing the potential versatility of HP ¹³C-MRI in diverse clinical contexts. This review serves as a comprehensive update, bridging technical aspects with clinical applications and offering insights into the ongoing advancements in HP ¹³C-MRI.

• 대한화학회지
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• 제34권5호
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• pp.452-459
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• 1990

일련의 산소 및 황 가교결합의 이핵 몰리브덴(V) 착물, Mo$_2$O$_4$L$_2$, Mo$_2$O$_3$L$_4$, Mo$_2$O$_2$S$_2$L$_2$, 그리고 Mo$_2$OS$_3$L$_2$, L = bis(hydroxyethyl)dithiocarbamate을 합성하였다. 말단과 가교의 산소결합 착물은 수용액에서 (PyH)$_2$MoOCl$_5$ 혹은 MoCl$_5$와 리간드의 반응으로부터 합성되었고, Mo$_2$O$_4^{2+}$핵에서 산소가 황으로 치환된 착물, Mo$_2$O$_2$S$_2$L$_2$은 Mo$_2$OS$_3$L$_2$의 클로로포름 용액에 트리페닐포스핀을 가하므로 합성되었다. 한편, Mo$_2$OS$_3$L$_2$착물은 sodium dithionite 존재하에서 (NH$_4$)$_2$MoS$_4$와 리간드의 수용액으로부터 얻어졌다. 합성한 착물에 대한 원소분석과 ir, uv-vis, nmr, 그리고 mass 스펙트라에 의한 착물의 분광학적 성질을 조사하였다. 또한 디메틸술폭시드 용액에서 이들 착물의 전기화학적 성질을 순환전압-전류법으로 조사하였다.

• 디지털융복합연구
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• 제15권11호
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• pp.547-555
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• 2017

본 연구는 대학생의 온라인 및 오프라인 사회적 자본과 심리적 복지감 간의 관계를 살펴보는 것을 목적으로 한다. 이를 위해 서울지역 4년제 대학에 재학 중이며 소셜 네트워크 서비스를 이용하고 있는 236명의 대학생을 대상으로 설문조사를 실시하였다. 본 연구의 종속변인인 대학생의 심리적 복지감은 우울과 행복으로 각각 측정하였고, 사회인구학적 변인과 온라인 및 오프라인 사회적 자본(연계형 및 결속형)을 독립변인으로 하는 위계적 회귀분석을 실시하였다. 우선 대학생의 우울을 예측하기 위해 사회인구학적 변수와 온라인 및 오프라인 사회적 자본을 함께 투입한 결과, 성별, 주관적 경제만족도, 오프라인 연계형 사회적 자본만이 대학생의 우울과 관련된 것으로 조사되었다. 다음으로 대학생의 행복을 예측하는데 있어 주관적 경제만족도와 오프라인 연계형 및 결속형 사회적 자본이 통계적으로 유의미한 변인으로 나타났다. 즉, 온라인과 오프라인 사회적 자본을 함께 고려하였을 경우 오프라인 사회적 자본만이 대학생의 우울과 행복과 같은 심리적 복지감에 영향을 미치는 것으로 조사되었다. 이와 함께 본 연구 결과의 시사점 및 정책적 제언에 대해 논의하였다.

• 한국임상약학회지
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• 제20권3호
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• pp.255-261
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• 2010

Cefprozil is a broad-spectrum oral beta-lactam cephalosporin consisting of cis- and trans-isomeric mixture whose ratio is approximately 90:10. Cefprozil is used to treat certain infections caused by bacteria such as bronchitis and ear, skin, and throat infections. The purpose of the present study was to evaluate the bioequivalence of two cefprozil tablets, $Cefzil^{(R)}$ tablet 250 mg (BMS Pharmaceutical Korea., Ltd.) and Procezil tablet 250 mg (Hanmi Pharm. Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The in vitro release of cefprozil from the two cefprozil formulations were tested using KP VIII Apparatus I method with water dissolution media. Thirty five healthy male subjects, $24.00{\pm}1.53$ years in age and $69.77{\pm}9.99$ kg in body weight, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After four tablets containing 1000 mg as cefprozil were orally administered, blood samples were taken at predetermined time intervals and the concentrations of cefprozil in serum were determined using HPLC/UV detector. The dissolution profiles of two formulations were similar in water tested dissolution media. The pharmacokinetic parameters such as $AUC_t$, $C_{max}$ and $T_{max}$ on the basis of total-cefprozil were calculated, and computer program (K-BE Test 2002) was utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t$, $C_{max}$ and untransformed $T_{max}$. The results showed that the differences between two formulations based on the reference drug, $Cefzil^{(R)}$ tablets, were -0.81%, -3.00% and -6.83% for $AUC_t$, $C_{max}$ and $T_{max}$, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log 0.8 to log 1.25 (e.g., log 0.9515~log 1.0454 and log 0.9613~log 1.0465 for $AUC_t$ and $C_{max}$, respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Procezil tablet was bioequivalent to $Cefzil^{(R)}$ tablet.