• Clinical and Experimental Pediatrics
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• 제45권11호
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• pp.1332-1339
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• 2002

목 적 : 이 연구는 소아과 진료를 표방하는 1차 의료 기관의 의사를 대상으로 영아기의 영양에 대한 설문 조사를 통해 이들이 영아기 영양에 대하여 얼마나 바르게 상담을 해 주고 있는지를 알아보기 위해 시행하였다. 방 법: 2000년 7월부터 8월까지 대구광역시에서 개원을 하고 있거나 봉직하고 있는 소아과 전문의(1군)와 소아과를 진료과목으로 표방하고 있는 비 소아과 전문의 또는 일반의(2군)를 대상으로 영아기 영양에 관한 육아 상담 내용을 미리 작성한 객관식 10문제를 이용하여 방문조사 하였다. 조사에 참여한 의사는 267명으로 소아과 전문의가 101명, 비 소아과 전문의 또는 일반의가 166명이었다. 비 소아과 전문의는 내과 63명, 일반외과 21명, 산부인과 20명, 가정의학과 16명, 이비인후과 7명, 정신과, 흉부외과, 신경과 전문의가 각각 1명이었다. 전문의 자격이 없는 일반의는 36명이었다. 결 과 : 100점 만점으로 평가한 결과 1군의 점수는 $73.0{\pm}15.8$점, 2군은 $45.1{\pm}18.4$점으로 두 군간에 의미 있는 차이가 있었다(P<0.05). 비소아과 전문의 중 전문 과목에 따른 점수는 내과 전문의가 $46.5{\pm}20.2$, 산부인과 전문의 $44.5{\pm}20.6$, 일반외과 전문의 $40.5{\pm}15.6$, 가정의학과 전문의 $56.3{\pm}16.9$, 이비인후과 전문의 $47.1{\pm}15.0$, 이었고 일반의 $45.3{\pm}16.3$ 점이었으며 타과 전문의와 일반의사 간의 점수사이에 통계적으로 유의한 차이는 관찰되지 않았다. 각 질문 항목에는 모유 수유 권장 기간, 모유 수유 중에 무른 변을 보이는 경우, 모유 수유시에 나타나는 황달의 대처 요령, 이유식의 시작 시기, 시판 이유식을 먹이는 형태, 식물성 분유에 대한 지도 방침, 선식에 대한 지도 방침에 대한 질문에 대한 대답이 1군과 2군 사이에 유의한 차이를 보였다. 결 론 : 본 조사 결과 소아과 전문의들에 비해 타과 전문의들이나 일반의들은 영아기의 영양에 대해 부적절하게 상담하고 있음을 알 수 있었으며, 소아과 전문의들에 대한 지속적인 교육과 함께, 타과 전문의에 의한 부적절한 상담이 이루어지지 않도록 대처하는 방안을 강구해야 할 것으로 사료되었다.

• 미생물학회지
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• 제52권1호
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• pp.18-24
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• 2016

본 연구에서는 우수한 아토피 완화능을 가진 유산균을 선별하기 위해 한국인 유아 분변으로부터 23종의 유산균을 분리하였다. 후보 균주들을 배양하여 열처리 된 세포와 상등액 농축물을 각각 얻었다. 우수 균주 선별은 마우스 비장세포를 이용하여 IL-4의 억제 및 IFN-${\gamma}$의 증가 정도를 확인하는 실험을 통해 진행되었다. 선별 실험 결과로 Lactobacillus rhamnosus IDCC 3201 (RH3201)을 OVA로 면역 반응을 유발시킨 BALB/c 마우스에 투여할 유산균으로 선정하였다. RH3201의 균체와 대사물을 경구 투여한 군에서는 유발군에 비해 혈중 IgE의 과다 생성이 억제된 것을 확인하였다. 그러한 알레르기 억제능은 type-1 T helper (Th1) 세포와 type-2 T helper (Th2) 세포의 싸이토카인 간의 균형을 향상시킴으로써 유도되었다. 따라서 RH3201의 균체와 배양물은 면역 조절을 통해 아토피 증상을 완화시킬 수 있음을 확인하였다.

• Journal of Nutrition and Health
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• 제23권3호
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• pp.179-186
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• 1990

모유에 함유된 총질소 함량과 각 질소원들의 농도를 분만후 2~3일, 1주, 2주에서 12주 까지 채취한 초유, 이행유 및 성숙유에서 측정하고, 수유기간에 따른 이들의 함량 변화를 비교 분석하였다. 모유의 총질소 함량과 각 질소원들의 농도는 분만 후 수유 초기에 현저하게 감소하였으며, 수유가 진되？체？ 성숙유에서도 완만한 감소 경향이 유의성 있게 나타났다. 특히 수유 초기 유즙에서는 Whey 단백질소 농도의 감소가 총질소 함량 변화에 가장 큰 영향을 주었다. 총질소 함량에 대한 비단백질소의 백분율은 초유와 이행유에서는 13%로 낮았으나, 6주 이후의 성숙유에서는 17~18%수준으로 큰 변화가 없었다. 또한 단백질소 중 초유의 whey 단백질소와 casein질소의 비율이 55:45에서 12주의 성숙유에서는 34:66으로 수유가 진행되면서, 점차 그 비율이 감소하는 것으로 나타났다. 수유 기간이 따른 이러한 질소원 사이의 상대적인 감소를 유발하는 요소는 무엇이며, 영아 영양과 관련하여 어떤 생리학적 의미가 부여될 수 있는가에 대해 보다 더 깊이 있는 연구가 앞으로 계속 수행되어야 할것이다.

• Advances in pediatric surgery
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• 제8권1호
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• pp.6-10
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• 2002

To clarify the necessity of surgery for fistula-in-ano (FIA) in infant, a retrospective analysis of 82 cases FIA in infant were performed for 11 years period from 1987 to 1998. Group A included 44 cases in the period of surgery oriented treatment to 1992, and group B contained 38, period of feeding control oriented management (FC) after 1993. FC, that was indicated in case with loose stool and eczematoid perianal skin (LSES), composed of quit breast feeding, change of cow milk or complete weaning. Surgical decision was made after improvement of stool condition. Fistulectomy was performed in 29 cases (65.9 %) of group A. However, in group B, only 15 cases (39.5 %) required surgery (p=0.0036). Thirty-four cases in B had the history of LSES, and Fe was applied in 25, and was effective in 24. Among 24 cases, 21 showed complete healing with FC, 3 had surgery because of the persistent FIA, and 1 got operation due to no improvement of stool condition. In conclusion, Fe has to be applied to FIA in infant before surgery, particularly in cases with history of LSES. As one of the etiologic factors for FIA, LSES could be considered to this particular age group.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제19권3호
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• pp.153-161
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• 2016

This paper covers algorithms for the management of regurgitation, constipation and infantile colic in infants. Anti-regurgitation formula may be considered in infants with troublesome regurgitation, while diagnostic investigations or drug therapy are not indicated in the absence of warning signs. Although probiotics have shown some positive evidence for the management of functional gastrointestinal disorders (FGIDs), the evidence is not strong enough to make a recommendation. A partially hydrolyzed infant formula with prebiotics and ${\beta}$-palmitate may be considered as a dietary intervention for functional constipation in formula fed infants. Lactulose has been shown to be effective and safe in infants younger than 6 months that are constipated. Macrogol (polyethylene glycol, PEG) is not approved for use in infants less than 6 months of age. However, PEG is preferred over lactulose in infants >6 months of age. Limited data suggests that infant formula with a partial hydrolysate, galacto-oligosaccharides/fructo-oligosaccharides, added ${\beta}$-palmitate may be of benefit in reducing infantile colic in formula fed infants in cases where cow's milk protein allergy (CMPA) is not suspected. Evidence suggests that the use of extensively hydrolyzed infant formula for a formula-fed baby and a cow's milk free diet for a breastfeeding mother may be beneficial to decrease infantile colic if CMPA is suspected. None of the FGIDs is a reason to stop breastfeeding.

• Journal of Nutrition and Health
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• 제34권1호
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• pp.98-111
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• 2001

The article demonstrates a method of studying human health and nutrition by applying a multi-disciplinary approach and examines how humans developed and survived by adjusting to their environment. This process involves physiological, cultural and genetic adaptation both independently and interactively. This study postulates that a sound human health may be the result of balance between nutrition and environmental conditions. It is noted that there is a positive correlation between malaria and fava bean intake, and sickle cell anemia and cassava intake. It is also suggested that the difference in disease structure in soybean and non-soybean consumption cultures can be explained by an ecological approach to studying nutrition. This study further suggest that the relationship between nutrition and socio-cultural system. epidmiological study of nutrition and cultural environment nutrition and conceptual characteristics, nutrition and food intake pattern, nutrition and health sociological functions and the physioloical, cultural and genetic adaptation can all be stimulating research subjects to be studied form and ecological point of view. This article also includes the results from a series of ecological studies conducted by the author investigating the relationship between nutritional status of Korean breast-feeding mothers and the composition of the human milk and also the Vitamin D status of Korean and their lifestyle. (Korean J Nutrition 34(1):98-111, 2001)

• Pediatric Infection and Vaccine
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• 제18권1호
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• pp.15-22
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• 2011

Invasive Candida infections (ICI) have become the third most common cause of late-onset infection among premature infants in the neonatal intensive care unit (NICU). Risk factors include birth weight less than 1,000 g, exposure to more than two antimicrobials, third generation cephalosporin exposure, parenteral nutrition including lipid emulsion, central venous catheter, and abdominal surgery. Candida colonization of the skin and gastrointestinal tract is an important first step in the pathogenesis of invasive disease. Strict infection control measures against the infection should be done in the NICU. The following practices are likely to contribute to reducing the rate of ICI: (1) restriction of broad-spectrum antibiotics, antacids and steroid; (2) introduction of early feeding and promoting breast milk. Fluconazole prophylaxis may be an effective control measure to prevent Candida colonization and infections in individual units with high incidence of fungal infection. In addition, there is a need of further data including the development of resistant strains and the effect on long-term neurodevelopmental outcomes of infants exposed to drugs before the initiation of routine application of antifungal prophylaxis in the NICU.

• Neonatal Medicine
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• 제16권2호
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• pp.131-136
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• 2009

Preterm infants are frequently discharged from the hospital with growth retardation. Given the potentially lifelong effects of growth impairmnet during a critical time of development, considerable effort should be focused on improving growth after discharge. Growth monitoring must be based on regular measurements of weight, length, and head circumference to identify those preterm infants with poor growth that may need additional nutritional support. Although prior studies vary in design and the intervention used, the evidence supports the use of fortified formulas in formula-fed preterm infants after discharge. The situation for infants fed human milk is much less clear, it seems prudent to concentrate our efforts on the encouragement of breast-feeding in this population. Catch up growth may have many benefits, and may lead to improved development. However, its long-term metabolic consequences are currently unclear. Understanding the optimal means of providing nutrition after discharge is an ongoing process.

• 부모자녀건강학회지
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• 제9권1호
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• pp.33-42
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• 2006

Objectives: The objective of this study was to provide an actual data for parents of infants about growth developmental status of brestfed infants. Methods: The subjects were 150 brestfed infants of 5, 6, 7 months as a primary nutrient source. Results: 1) The mean score of growth developmental status of subjects were $8.6({\pm}1.15)$ and $9.5(({\pm}.58)$ at the highest points of 10.0. 2) The growth status was signifant difference according to feeding type(t=-2.076, p=.040), development status was signifant difference according to infant age(F=8.272, p=.000). Conclusions: The main point infants breast milk is very beneficial to infants growth development status. This result can be used as an important guide for nurses to teach the infants parents.

• 재활간호학회지
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• 제2권2호
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• pp.234-242
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• 1999

The meaning of the study is in the following points. The first is to find the linguistic development of children through IQ test. The second is to find the family fostering factor for the linguistic development. For these meaning this study will have the following aims. 1) To judge the similarly agreement between the children lexical ability with the teachers evaluation to the children. 2) To compare the gender differences of lexical abilities between the urban with the rural. 3) To find the family fostering factors for the children linguistic development. The collection data has been from April 13, 1999 to April 27. The subjects for this study were two grade of elementary school, which is located in "K" city and "O"rural a chosen students(273), teachers(5), parents(176). The instruments used for this study were IQ test by Korea Behavioral Science institute and family fostering environment 25 items. Teachers linguistic evaluation. The data analysis was done using Pearson's Correlation Coefficient, t-test, ANOVA using SPSS/pc program. This study found following results. 1) The similarly agreement degree between children lexical abilities with teachers comprehending evaluation maler r= .745, female r=0.809 The similarly agreement degree between children lexical abilities with teachers expressing evaluation, male r= .657, female r= .797(P<.01) 2) In comparing of the gender difference of urban, the femail is a little high than male(t= .5065), but the especial point is more large difference in male than in female. In comparing of the gender difference of rural, the female is especial high than the male(t=-4.411). (P<.01) 3) The higher factor of influencing the linguistic development is the breast-feeding(r=-.3279) in all the gender(P<.01), So that the brast-feeding better than cow's milk, mother better than the other family members in feeding, 6~8months better than one or two years in feeding term.