• Investigative Magnetic Resonance Imaging
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• 제13권1호
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• pp.101-105
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• 2009

저자들은 육종의 일종으로 분류되는 유방의 악성 엽상종양이 골격근으로 전이된, 현재까지 영상소견으로는 보고된 사례가 없는, 드문 증례의 초음파, 양전자방출 단층촬영, 전산화 단층 촬영, 자기공명영상 소견을 보고하고자 한다.

• The Korean Journal of Pain
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• 제34권4호
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• pp.375-393
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• 2021

Percutaneous osteoplasty (POP) is defined as the injection of bone cement into various painful bony lesions, refractory to conventional therapy, as an extended technique of percutaneous vertebroplasty (PVP). POP can be applied to benign osteochondral lesions and malignant metastatic lesions throughout the whole skeleton, whereas PVP is restricted to the vertebral body. Common spinal metastases occur in the thoracic (70%), lumbosacral (20%), and cervical (10%) vertebrae, in order of frequency. Extraspinal metastases into the ribs, scapulae, sternum, and humeral head commonly originate from lung and breast cancers; extraspinal metastases into the pelvis and femoral head come from prostate, urinary bladder, colon, and uterine cervical cancers. Pain is aggravated in the dependent (or weight bearing) position, or during movement (or respiration). The tenderness and imaging diagnosis should match. The supposed mechanism of pain relief in POP is the augmentation of damaged bones, thermal and chemical ablation of the nociceptive nerves, and local inhibition of tumor invasion. Adjacent (facet) joint injections may be needed prior to POP (PVP). The length and thickness of the applied needle should be chosen according to the targeted bone. Bone cement is also selected by its osteoconduction, osteoinduction, and osteogenesis. Needle route should be chosen as a shortcut to reach the target bony lesions, without damage to the nerves and vessels. POP is a promising minimally invasive procedure for immediate pain relief. This review provides a technical survey for POPs in painful bony lesions.

• 임상이비인후과
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• 제29권2호
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• pp.290-294
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• 2018

Mammary analogue secretory carcinoma (MASC) has histologic similarities to not only acinic cell carcinoma but also other low grade cystadenocarcinoma, and has similar features to breast secretory carcinoma. MASC was not described through the existing classification system previously. But, MASC was distinguished from other salivary gland tumors by Skalova et al. in 2010, MASC has ets variant gene 6-neurotrophic tyrosine kinase, receptor, type 3 (ETV6-NTRK3) translocation. So far, there are 4 cases of MASC recognized in the head and neck region in Korea. One of the four is a tumor from the submandibular gland, and the other three are of the parotid gland. In this case report, we report a 40-year-old man with a MASC of the parotid gland, who presented with right infra-auricular mass.

• 여성건강간호학회지
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• 제25권2호
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• pp.219-231
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• 2019

Purpose: The purpose of this study was to identify the levels of body image, sexual intimacy, and sexual satisfaction, and to explore factors affecting sexual intimacy and satisfaction among women within one year of mastectomy. Methods: The present study was a cross-sectional survey and involved 101 women who had undergone mastectomy at a University hospital of D city, Korea. Measurement included the scales of body image, sexual intimacy, and sexual satisfaction. Results: Mean age of the subjects was 51 years. Scores of the body image, sexual intimacy, and sexual satisfaction were 59.62, 90.69, and 69.04, respectively. Body image, sexual intimacy, and sexual satisfaction were significantly related to each other. Sexual intimacy was higher when women were of young age (${\beta}=-.32$), had a shorter period since surgery (${\beta}=-.24$), and with higher levels of body image (${\beta}=.37$). Sexual satisfaction was higher when women had higher levels of body image (${\beta}=.19$) and greater levels of sexual intimacy (${\beta}=.74$). Conclusion: Higher levels of body image and greater levels of sexual intimacy were identified as the significant factors influencing sexual satisfaction among these women. Future research with a mixed-method research is needed to gain a deep understanding of the sexuality between women and their husbands.

• Journal of Chest Surgery
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• 제56권1호
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• pp.53-55
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• 2023

Silicone granulomas are rare, benign lesions that may occur after breast augmentation. Occasionally, a careful differential diagnosis is necessary because lymphadenopathy or malignancy is suspected based on an imaging study. A 56-year-old woman who visited the hospital due to a lung nodule in the left upper lobe (LUL) underwent a staging work-up with the suspicion of lung cancer. Positron emission tomography/computed tomography and chest computed tomography revealed the LUL nodule and a lesion in the left internal mammary chain (IMC), suggesting lymphadenopathy. Diagnostic wedge resection was performed, followed by curative surgery. The final biopsy result confirmed that the LUL nodule was pathologic stage IB adenocarcinoma; unexpectedly, the lesion in the left IMC was a silicone granuloma.

• Journal of Hospice and Palliative Care
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• 제26권2호
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• pp.80-94
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• 2023

Purpose: This study aimed to identify attitudes toward advance directives (ADs) among female cancer patients and factors related to ADs. Methods: The study was conducted at a university hospital in Seoul from September 19, 2020, to January 20, 2021. The participants were 153 patients diagnosed with gynecological cancer or breast cancer. Data were collected using questionnaires and included general characteristics, disease- and AD-related characteristics, knowledge and attitudes about ADs, and attitudes about dignified death. Data were analyzed using the t-test, analysis of variance, and multiple regression analysis. Results: Only 2% of the participants completed ADs. The mean score for attitudes toward ADs was 3.30, indicating a positive knowledge and attitude toward dignified death. The factors related to attitudes toward ADs were attitudes toward dignified death (𝛽=0.25, P=0.001), experience discussing life-sustaining treatment (𝛽=0.17, P=0.037), preferred time to have a consultation about ADs (𝛽=0.19, P=0.046), intention to write ADs (𝛽=0.15, P=0.038), and Eastern Cooperative Oncology Group Performance Status (𝛽=-0.37, P<0.001). The explanatory power of these variables for attitudes toward ADs was 38.5%. Conclusion: Overall, patients preferred to have a consultation about ADs when they were still active, mentally healthy, and able to make decisions. Education about ADs should be provided to patients on the first day of hospitalization for chemotherapy or while awaiting treatment in an outpatient setting so patients can write ADs and discuss them with family and friends.

• 대한한방내과학회지
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• 제43권6호
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• pp.1075-1088
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• 2022

Objectives: The aim of this study is to analyze cancer research trends in traditional Korean medical journals indexed in the Korea Citation Index since 2000. Methods: Cancer research papers published in traditional Korean medical journals were searched in databases from inception to October 2022. The numbers of publications by journal and by year were descriptively assessed. After natural language processing, topic modeling (based on Latent Dirichlet allocation) and keyword network analysis were conducted. Results: This research trend analysis involved 1,265 papers. Six topics were identified by topic modeling: case reports on symptom management, literature reviews, experiments on apoptosis, herbal extract treatments of breast carcinoma cell lines, anti-proliferative effects of herbal extracts, and anti-tumor effects. Keyword network analysis found that the effects of herbal medicine were assessed in clinical and experimental studies, while acupuncture was mainly mentioned in clinical reports. Conclusions: Cancer research papers in traditional Korean medical journals have contributed to evidence-based medicine. Further experimental studies are needed to elucidate the effects of on different hallmarks of cancer. Rigorous clinical studies are needed to support clinical guidelines.

• 대한영상의학회지
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• 제83권6호
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• pp.1327-1341
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• 2022

목적 국내 디지털 유방 토모신테시스(digital breast tomosynthesis; 이하 DBT) 사용 현황 및 영상의학과 의사들의 DBT에 대한 인식 및 사용자 요구조건에 관해 알아보고자 하였다. 대상과 방법 2021년 3월 대한 유방영상의학회 회원들을 대상으로 DBT와 관련한 26개의 객관식 문항과 1개의 주관식 문항이 포함된 온라인 설문조사를 시행하였다. 설문 문항은 기본 정보, 유방촬영술 및 DBT에 대한 진료 현황, DBT 인식, 관련 연구 경험 및 관심도를 포함하였다. 결과는 로지스틱 회귀분석을 이용하여 분석하였다. 결과 총 257명의 회원 중 120명이 응답하여, 응답률은 46.7%였다. 응답자 중 67명(55.8%)이 현재 DBT를 사용하고 있는 것으로 나타났다. DBT의 전반적인 만족도는 5점 척도를 사용하여 평균 3.31점이었다. DBT 검사의 장점으로 가장 많이 응답한 것은 소환율 감소(55.8%), 병변의 명확도 향상(48.3%), 유방암 발견율 향상(45.8%)이었고, 단점으로 많이 응답한 것은 환자의 추가비용 부담46.7%), 불충분한 미세석회화 검출(43.3%), 불충분한 진단능 향상 효과(39.2%), 방사선량 증가(35.8%)였다. DBT가 더 널리 사용되지 못하는 원인으로는 영상의 저장 용량, 판독 시간 증가를 주요 요인으로 응답하였다. 결론 DBT 사용이 보다 보편화되기 위해서는 사용자 불편사항과 피드백을 반영한 향후 기술개발이 필요하겠다.

• 대한영상의학회지
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• 제81권2호
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• pp.395-408
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• 2020

목적 유방암 일차치료 후 조기 재발 예측에 도움이 되는 임상병리학적 인자 및 원발암의 영상의학적 특징을 알아보고자 하였다. 대상과 방법 본원에서 2010년 1월부터 2014년 12월까지 유방 보존 수술 및 보조요법 치료 후 추적관찰을 받은 480명을 대상으로 하였다. 일차치료 완결 후 3년 이내 재발한 경우를 조기재발으로 정의하고, 이와 관련된 임상병리학적 및 영상의학적 예측인자를 알아보기 위해 단변량 및 다변량 로지스틱 회귀분석을 시행하였다. 결과 단변량 분석에서 임상병리학적 인자 중 높은 종양 병기(p = 0.021), 고등급 조직학적 분화도(p < 0.001), estrogen receptor 수용체 음성(p = 0.002), Ki-67 과발현(p = 0.017), 삼중음성유방 아형(p = 0.019)과, 영상 소견 중 유방암의 다초점성(p < 0.001), 도플러 검사에서 테두리 혈류(p = 0.012), 자기공명영상에서 테두리 조영증강(p < 0.001)이 조기 재발과 유의한 연관성을 보였다. 다변량 분석에서 원발암의 높은 종양 병기[odds ratio (이하 OR) = 3.47, 95% confidence interval (이하 CI) 1.12~10.73, p = 0.031]와 도플러 검사에서 테두리 혈류 (OR = 3.32, 95% CI 1.38~8.02,p = 0.008)가 조기 재발과 관련된 독립적인 예측인자였다. 결론 유방암 치료 전 도플러 검사에서 원발암의 테두리 혈류 소견은 유방암의 일차치료 후 조기 재발의 독립적인 영상의학적 예측인자이다.

• Investigative Magnetic Resonance Imaging
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• 제14권1호
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• pp.21-30
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• 2010

목적: 점액암의 영상소견에 대해서 알아 보고, 조직학적 분화도에 따른 영상 소견의 차이를 알아보고자 하였다. 대상과 방법: 수술을 통해 점액암으로 확진된 29명의 환자를 대상으로 유방촬영술과 초음파 검사, 그리고 자기 공명 영상 소견을 BI-RADS에 따라서 후향적으로 분석하였다. 또한 점액암의 조직학적 분화도를 고분화, 중증도분화, 미분화 등급으로 나눠서 이에 따른 영상소견의 차이를 통계학적으로 분석하였다. 결과: 총 20예의 유방 촬영에서 17예 (85%)가 종괴로 보였고 3예는 정상소견이었다. 총 27예의 초음파 검사에서 점액암은 난원형 (59.2%)의 미세소엽성 변연 (55.5%)을 가지거나 불균일한 등에코 (74%)의 종괴로 보였다. 총 21예의 자기공명영상에서 점액암은 소엽상의 변연(76.2%), 매끄러운 변연(86%)의 종괴로 불균일한 조영증강(61.9%)을 보이는 경우가 흔하였다. 역동성 조영 증가 그래프에서 지연시 유실형 양상 (52.3%)을 보였다. 고분화 점액암이 갑자기 끝나는 종괴의 경계를 보이는 것 외에는 점액암의 분화도에 따른 영상소견의 차이는 없었다. 결론: 점액암의 분화도에 따른 차이는 중등도 분화 점액암과 비교하여 고분화 점액암이 갑자기 끝나는 종괴의 경계를 보이는 것이었다. 대부분의 점액암은 자기공명영상에서 불균일한 조영증강과 지연시 유실형 양상을 보였다.