• 대한간호학회지
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• 제48권6호
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• pp.669-678
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• 2018

Purpose: The purpose of this study was to examine the effects of integrated psychoeducational program for distress management of newly diagnosed patients with breast cancer. Methods: A quasi-experimental trial was conducted. The participants consisted of 47 female patients with breast cancer assigned to an intervention group (n=25) and control group (n=22). The intervention group participated in integrated psychoeducational program, consisting of individual face-to-face education and telephone-delivered health-coaching sessions. Data were collected at three time points: pre-intervention (T1), post-intervention (T2), and 6-month follow-up (T3). Study instruments were Distress thermometer, Supportive Care Needs Survey Short Form 34 and Functional Assessment of Cancer Therapy-Breast. Results: Compared with the control group, breast cancer patients in the intervention group reported lower distress and supportive care needs than the control group. The intervention group reported higher quality of life (QOL) overall and higher emotional well-being than the control group. Conclusion: These findings indicate that the integrated psychoeducational program is an effective intervention for reducing distress and supportive care needs and increasing QOL of newly diagnosed patients with breast cancer. Oncology nurses need to provide psychoeducational intervention to support patients with breast cancer in managing their distress and helping them adjust to their life.

• 대한영상의학회지
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• 제81권6호
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• pp.1504-1510
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• 2020

이 증례 보고는, 남성 유방에서의 비정형유관증식증 소견에 대한 영상의학적, 병리학적 소견을 담고 있다. 비정형유관증식증은 고위험 병변에 속하며 유방암의 전구 병변으로 잘 알려져 있다. 하지만, 이런 병변이 남성 유방에서 어떠한 임상적 의미를 갖는지는 잘 알려져 있지 않다. 남성 유방은 여성 유방과 달리 유관이 소엽을 구성하지 않기 때문이다. 지금까지 이러한 전구 병변의 영상 소견과 병리학적 소견을 다룬 문헌은 극소수이다. 이 증례 보고를 통해, 우리는 남성 유방에서 유방암 전구 병변의 가능한 영상 및 병리 소견을 제시하고, 문헌고찰을 하고자 한다.

• Journal of Breast Cancer
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• 제21권4호
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• pp.415-424
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• 2018

Purpose: Triple-positive breast cancer is defined by estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 (HER2) positivity. Several systemic breast cancer therapies target hormonal and HER2 responsiveness. We compared clinical outcomes of triple-positive disease with those of HER2-enriched and luminal HER2-negative disease and investigated the clinical efficacy of anti-HER2 therapy for triple-positive disease. Methods: We retrospectively compared overall and recurrence-free survival among cases included in the Korean Breast Cancer Society (KBCS) and Seoul St. Mary's Hospital breast cancer registries and the therapeutic efficacy of trastuzumab for triple-positive and HER2-enriched cases. Results: KBCS registry data (2006-2010; median follow-up, 76 months) indicated that patients with triple-positive breast cancer had intermediate survival between those with luminal A and HER2-enriched subtypes (p<0.001). Trastuzumab did not improve overall survival among patients with triple-positive breast cancer (p=0.899) in contrast to the HER2-enriched subtype (p=0.018). Seoul St. Mary's Hospital registry data indicated similar recurrence-free survival outcomes (p<0.001) and a lack of improvement with trastuzumab among patients with triple-positive breast cancer (median follow-up, 33 months; p=0.800). Multivariate analysis revealed that patients with triple-positive breast cancer had better overall survival than those with HER2-enriched disease and similar survival as those with the luminal A subtype (triple-positive: hazard ratio, 1.258, p=0.118; HER2-enriched: hazard ratio, 2.377, p<0.001). Conclusion: Our findings showed that anti-HER2 therapy was less beneficial for treatment of triple-positive breast cancer than for HER2-enriched subtypes of breast cancer, and the triple-positive subtype had a distinct prognosis.

• Asian Pacific Journal of Cancer Prevention
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• 제13권1호
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• pp.123-125
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• 2012

Purpose: The purpose of this study was to identify the current status of the awareness and practice of breast self-examination (BSE) among Korean women. Materials and Methods: The study population was derived from the 2007 Korea National Cancer Screening Survey (KNCSS), an annual cross-sectional survey that uses a nationally representative random sample to investigate cancer-screening rates and related factors. A total of 1,255 Korean women aged ${\geq}30$ years participated in this study. Results: Of all participants, 88.0% reported that they had heard of BSE. The most common source of information on BSE was the media such as TV, radio and newspapers (87.0%). Recommendations from medical staff reached only 17.2%. The overall proportions of regular and irregular BSE were 13.2% and 16.1%, respectively. The main reason for not performing BSE was lack of knowledge about how to conduct the exam (31.7%). Conclusion: Despite a high level of awareness about BSE, only a small minority of women examine their breasts regularly in Korea.

• 대한간호학회지
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• 제42권5호
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• pp.644-658
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• 2012

Purpose: The purpose of this study was to evaluate the cognitive effects of chemotherapy in patients with breast cancer. Methods: Using several databases, prospective studies were collected up to August 2011. Of 2,106 publications identified, 12 met the inclusion criteria, and 8 studies were used to estimate the effect size of chemotherapy on cognitive impairment. Results: Twelve studies were done since 2005 and most of the research was performed in Europe or North America. Eight studies were used to generate effect size across the cognitive domains of attention/concentration, verbal and visual memory, executive function, visuospatial skill, language, and subjective cognitive function. Each of the cognitive domains showed small effect sizes (-0.02 ~ -0.26), indicating diminished cognitive function for the chemotherapy group compared with non-chemotherapy groups. Conclusion: Finding suggests that breast cancer patients who undergo chemotherapy may experience mild cognitive decline. Further study is needed to generate knowledge and guideline for interventions to address chemotherapy related cognitive impairment in these patients.

• 임상간호연구
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• 제21권2호
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• pp.180-187
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• 2015

Purpose: This study was done to identify the effects of semen sinapsis albae acupressure on fatigue and sleep among patients undergoing chemotherapy for breast neoplasms. Methods: The design was a nonequivalent control group nonsynchronized design. Participants were 46 hospitalized patients (23 in the experimental group and 23 in the control group) who were undergoing chemotherapy during November and December 2014. The experimental group underwent routine chemotherapy nursing care and at the same time received acupressure on the spots of Zoksamli, Samumgyo and Shinmun. The control group underwent routine chemotherapy nursing care. The data were analyzed using test and t-test with the SPSS 21.0 program. Results: The level of fatigue in the experimental group was lower than in the control group (t=5.82, p<.001). The level of sleep in the experimental group was higher than in the control group (t=-5.16, p<.001). Conclusion: The findings of the study indicate that acupressure is an effective nursing intervention to decrease fatigue and increase sleep in patients with breast neoplasm undergoing chemotherapy.

• Journal of Yeungnam Medical Science
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• 제37권3호
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• pp.230-235
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• 2020

Systemic therapy for metastatic triple-negative breast cancer (TNBC) still remains challenging because there are no targeted agents or endocrine therapies currently available. The present case report documents the successful use of cisplatin monotherapy to manage a heavily pretreated TNBC patient showing poor response to therapy. The patient was a 51-year-old woman who had already undergone several lines of systemic chemotherapy for widespread TNBC. Although the mutation analysis performed on DNA isolated from blood cells and progressed lesion samples confirmed the tumor to be germline BRCA wild-type, cisplatin monotherapy was administered based on the increasing evidence of safety and efficacy of platinum for breast cancer. After three cycles of cisplatin treatment, the patient's metastatic lesions dramatically improved without any major toxicity, and she completed 17 cycles with good response. This case study indicates that patients with heavily pretreated TNBC can potentially achieve a good response to cisplatin monotherapy.

• 종양간호연구
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• 제10권2호
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• pp.199-209
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• 2010

Purpose: The purpose of this study was to understand the meaning of prayer in Christian patients with breast cancer. Methods: Data collection and analysis were conducted by the Colaizzi analysis of phenomenological method. Data were collected by in-depth interviewing the participants and by further follow-up observations. Sixteen patients participated in this study. Results: The significant statements (188), formulated meanings (42), themes (38), clusters of theme (10), and categories (5) were emerged. The 5 categories were as follows: communication with God, healing and peace, spiritual growth, distrust in prayer, and method of prayer. Conclusion: Further studies need to consider the period of faith, comparison between christian and other religions, and length of diagnosis. A better understanding of the meaning of prayer will lead to a more comprehensive view of the spiritual care for patients with breast cancer, and can lead to guidelines for assessment and intervention to reduce suffering from cancer.

• 여성건강간호학회지
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• 제27권3호
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• pp.243-255
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• 2021

Purpose: This study aimed to develop a lifestyle modification (LSM) mobile application based on the Android operating system for overweight and obese breast cancer survivors (BCS) in Korea and evaluate its usability. Methods: The content analysis, design, development, implementation, and evaluation of the LSM intervention mobile application for overweight and obese BCS was conducted by identifying survivors' needs, searching the literature, and reviewing existing mobile applications. The survey was conducted from June 1 to December 28, 2020 at Jeonju, Korea. Results: The mobile application for BCS included dietary and exercise information, weight logs, as well as distress and daily achievement check. It also included information and videos on the prevention of breast cancer recurrence and used a communication bulletin board. Expert and user usability evaluation of its content and functions confirmed that it was appropriate and satisfactory for overweight and obese BCS. Conclusion: This LSM mobile application developed for overweight and obese BCS was found to be appropriate for use. It can be applied for further study of effectiveness on improving their health and maintaining a healthy lifestyle, to ultimately improve quality of life.

• Archives of Plastic Surgery
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• 제48권6호
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• pp.577-582
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• 2021

Robot-assisted surgery is evolving to incorporate a higher number of minimally invasive techniques. There is a growing interest in robotic breast reconstruction that uses autologous tissue. Since a traditional latissimus dorsi (LD) flap leads to a long donor scar, which can be an unpleasant burden to patients, there have been many attempts to decrease the scar length using minimally invasive approaches. This study presents the case of a patient who underwent a robot-assisted nipple-sparing mastectomy followed by immediate breast reconstruction with an LD flap using a single-port robotic surgery system. With the assistance of a single-port robot, a simple docking process using a short and less visible incision is possible. Compared to multiport surgery systems, single-port robots can reduce the possibility of collision between robotic arms and provide a clear view of the medial border of the LD where the curvature of the back restricts the visual field. We recommend the use of single-port robots as a minimally invasive approach for harvesting LD flaps.