• Journal of Life Science
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• v.20 no.11
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• pp.1603-1610
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• 2010

Fucoidans are sulfated fucosylated polymers from the cell wall of brown algae. We assessed the effects of Fucus evanescens fucoidan on ultraviolet-B (UVB)-induced expression of matrix metalloproteinase-1 (MMP-1) protein, mRNA, and promoter, and the phosphorylation of mitogen-activated protein kinases in vitro using an immortalized human keratinocyte cell line. Pretreatment with 10 and $100\;{\mu}g/ml$ fucoidan significantly inhibited UVB-induced MMP-1 protein, mRNA and promoter activity, compared to UVB irradiation alone. Extracellular signal regulated kinase activation was markedly inhibited by treatment with fucoidan, though c-JUN N-terminal kinase activity and p38 activation were only marginally affected by fucoidan. F. evanescens fucoidan may be a potential therapeutic agent for the prevention and treatment of skin photoaging.

• FLOWER RESEARCH JOURNAL
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• v.18 no.2
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• pp.125-135
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• 2010

To discover the main characteristics of Korean traditional flower arrangement, they were compared with different articles and old paintings used in royal court ceremonies. The primary research involved principle of design. The times periods used were the Joseon Dynasty era of Korea, the Ming era of China, and the Edo eras of Japan. The result, which shows both the similarities and differences, of the research is summarized as follows. The similarities were that they all respect the features of nature, and their image expresses their creator's thinking. There was one technique, called 'Suje', in which a part of the stem is coming out from one branch. Also, each three eras preferred flowering trees and ornamental trees more than annuals or foliage plants. one of the differences was that korea used a simple number of materials. The work had volume and appeared mild by using a soft curved line which was repetitive and massive. The Joseon Dynasty era advanced a sense of beauty with artistic symmetry and balance. The work seemed soft and natural because of the little change in blank space, with almost no angle of line. The form had a characteristic preference of being taller than the typical Japanese arrangement. It appeared simple, calm, and rustic by using only one kind of material. In contrast, the Chinese style was gorgeous and displayed volume in a non-symmetrical tripodal form, which incorporated various colors and materials. Also, they avoided processing the materials in order to emphasize the original beauty of nature. Chinese flower arts did not become formalized because they did not consider the formality seriously the formal. The Japanese style was also gorgeous because it incorporated various materials and angles. It included an extreme technique in which an artificial line divided the blank space delicately. The line was both strong and delicate in an established form. The restriction of the main branch gave a light feeling, as well as more strain as in a balance sense. The Japanese eras emphasized more the use of line and a sense of blank space.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.11
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• pp.5434-5441
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• 2012

In the low-density branch line section of domestic railway, the necessity for development of new concept on-board centered train control system which can control the trackside equipment directly from the on-board of train is on the rise since it is problematic in the aspect of efficiency because of its operation in deficits, etc. in accordance with the operation of high-priced wayside equipment being applied to main lines. Accordingly, this paper proposed an on-board control system which can minimize wayside equipment and replace the existing system with it simultaneously by grafting the advanced domestic Information & Communication Technology(ICT), and presented contents of performing confirmation of function through results of concept and detailed design and by building model test environments.

• Proceedings of the IEEK Conference
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• 2005.11a
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• pp.765-768
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• 2005

In this paper, high LO-RF isolation 94 GHz MMIC single-balanced mixer was designed and fabricated using a branch line coupler and a ${\lambda}/4$ transmission line. The 94 GHz MMIC single-balanced mixer was designed using the 0.1 ${\mu}m$ InGaAs/InAlAs/GaAs Metamorphic HEMT(MHEMT) diode. The fabricated MHEMT was obtained the cut-off frequency($f_T$) of 189 GHz and the maximum oscillation frequency($f_{max}$) of 334 GHz. The designed MMIC single-balanced mixer was fabricated using 0.1 ${\mu}m$ MHEMT MMIC process. From the measurement, the conversion loss of the single-balanced mixer was 23.1 dB at an LO power of 10 dBm. The LO-RF isolations of single-balanced mixer was obtained 45.5 dB at 94.19 GHz. We obtained in this study a higher LO-RF isolation compared to some other balanced mixers in millimeter-wave frequencies.

• Journal of Mechanical Science and Technology
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• v.17 no.10
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• pp.1423-1430
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• 2003

In this paper, we develop a real time monitoring system to detect third-party damage on natural gas pipeline. When the damage due to third-party incidents causes an immediate rupture, the developed on-line monitoring system can help reducing the sequences of event at once. Moreover, since many third-party incidents cause damage that does not lead to immediate rupture but can grow with time, the developed on-line monitoring system can execute a significant role in reducing many third-party damage incidents. Also, when the damage is given at a point on natural gas pipeline, the acoustic wave is propagated very fast about 421.3 m/s. Therefore, the data processing time should be very short in order to detect precisely the impact position. Generally, the pipeline is laid under ground or sea and the length is very long. So a wireless data communication method is recommendable and the sensing positions are limited by laid circumstance and setting cost of sensors. The calculation and monitoring software is developed by an algorithm using the propagation speed of acoustic wave and data base system based on wireless communication and DSP systems. The developed monitoring system is examined by field testing at Balan pilot plant, KOGAS being done in order to demonstrate its validity through reactive detection of third-party contact with pipelines. Furthermore, the development system was set at the practical pipelines such as an offshore pipeline between two islands Yul-Do and Youngjong-Do, and a land branch of Pyoungtaek, Korea and it has been operating in real time.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.5
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• pp.1131-1136
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• 2015

VoIP and IP Telephony telephony technology development is a growing by easy to using IP-PBX by using phone from using existing lines rather than the internet. IP-PBX do not use the phone line from phone work for many companies and institutions of management costs reduce as provides similar to regular phone line quality. But IP-PBX to introduce for need to be the initial cost on is should buy for expensive hardware equipment or commercial software. In this paper, suggest way to introduce IP-PBX do not buy expensive hardware equipment or commercial software. Suggest IP-PBX on designed and implement for IP-PBX server using Raspberry Pi and Asterisk. And verification treatise on the suitability of conducted by voice calls based on IP-PBX between PC and a Smartphone

• Molecules and Cells
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• v.28 no.6
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• pp.553-558
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• 2009

In the periphery, a galectin-1 receptor, CD7, plays crucial roles in galectin-1-mediated apoptosis of activated T-cells as well as progression of T-lymphoma. Previously, we demonstrated that $NF-{\kappa}B$ downregulated CD7 gene expression through the p38 MAPK pathway in developing immature thymocytes. However, its regulatory pathway is not well understood in functional mature T-cells. Here, we show that CD7 expression was downregulated by Twist2 in Jurkat cells, a human acute T-cell lymphoma cell line, and in EL4 cells, a mature murine T-cell lymphoma cell line. Furthermore, ectopic expression of Twist2 in Jurkat cells reduced galectin-1-induced apoptosis. While full-length Twist2 decreased CD7 promoter activity, a C-terminal deletion form of Twist2 reversed its inhibition, suggesting an important role of the C-terminus in CD7 regulation. In addition, CD7 expression was enhanced by histone deacetylase inhibitors such as trichostatin A and sodium butyrate, which indicates that Twist2 might be one of candidate factors involved in histone deacetylation. Based on these results, we conclude that upregulation of Twist2 increases the resistance to galectin-1-mediated-apoptosis, which may have significant implications for the progression of some T-cells into tumors such as Sezary cells.

• Journal of Electrical Engineering and Technology
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• v.9 no.1
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• pp.301-306
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• 2014

We proposed a new PCB-type 'common-mode current($I_c$) and differential-mode current($I_d$) detector' working for fast detection of $I_c$ and $I_d$ from the differential-mode signaling, with miniaturization effect and possibility of cheaper fabrication. In order to realize this device, we suggest a branch-line-coupler balun having a composite right- and left-handed(CRLH) one-layer microstrip phase-shifting line as compact as roughly ${\lambda}_g/14$. The presented balun obviously is different from the conventional bent-&-folded delay lines or slits on the ground for coupling the lines on the top and bottom dielectrics. As we connect the suggested balun output ports of the differential-mode signal lines via the through-port named U and coupled-port named L, $I_c$ and $I_d$ will appear at port ${\Delta}$ and port ${\Sigma}$ of the present device, in order. The validity of the design scheme is verified by the circuit-and numerical electromagnetic analyses, and the dispersion curve proving the metamaterial characteristics of the geometry. Besides, the examples of the $I_c$ and $I_d$ indicator are observed as the even and odd modes in differential-mode signal feeding. Also, the proposed device is shown to be very compact, compared with the conventional structure.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.22 no.1
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• pp.124-131
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• 2008

Recently underground electrical power distribution is increased because people attach importance to aesthetics of the downtown areas. Lew-voltage handhole of underground distribution line for joint and branch point is mainly installed at the sidewalk. So, pedestrian can get a electric shock if fault is occurred in the low-voltage handhole. Furthermore the street was flooded by recently an unusual change in the weather. Fault is occurred in the low-voltage handhole that may create a shock hazard for the human body because a person's body resistance lower due to effect of water. This paper analyses causes of electric shock accidents and check results at the low-voltage handhole. At a result of analysis, the causes of electric shock accidents in domestic and foreign low-voltage handhole are same but environmental conditions of low-voltage handhole are different In the future, the analytical data can be applied to prevent the electric shock at the low-voltage handhole, and can be used to basic data for the improving installment of low-voltage handhole.

• Advances in nano research
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• v.4 no.2
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• pp.145-156
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• 2016

Dendrimers are one of the most appropriate nanocaries for imaging moieties in imaging applications.The purpose of this study was the evalution of cytotoxicity and inducing apoptosis of dendrimers. This study was conducted in order to investigate the metastasis suppression effect of dendrimer in human breast MCF-7 cell line and finding the nanoparticle protein corona in biological enviromental. Dendrimer cytotoxicity effect was assessed by MTT assay. The mRNA experession level of KAI1 as a metastasis suppressor gene, Bax as Pro- apoptotic gene, Bcl-2 as an anti-apoptotic gene and GAPDH as a housekepping gene were determined by real-time PCR assays.concentration-dependent nanoparticle cytotoxicity effect was proofed at range of 1-2 mg/mL in 24 hours, significant upregulation of mRNA expression of Bax, was observed whereas expression of anti-apoptotic Bcl-2 was down-regulated, also expression of metastasis suppressor gene KAI1 was up-regulated. So far a few studies confirmed apoptosis enhancement effect of dendrimers in MCF-7 cell line via bax/bcl-2 pathways. dendrimer nanoparticles was able to act as metastase inhibitor via upregulation of KAI1 gene.