• PNF and Movement
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• v.5 no.1
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• pp.9-17
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• 2007

Purpose : The purpose of this study was to test the effect of balance training for proprioceptive and vestibular sensory stimulation and therapeutic environment on expression of BDNF after traumatic brain injury in the rat. Subject : Twelve Sprague-Dawley rats were randomly assigned into group I and group II. After traumatic brain injury, group I was housed in standard cage for 7 days. Group II was housed in therapeutic cage after balance training for 7 days. Method : Traumatic brain injury was induced by weight drop model and after operation they were housed in individual standard cages for 24 hours. After 7th day, the rats were sacrificed and cryostat coronal sections were processed individually in goat polyclonal anti-BDNF antibody. The morphologic characteristics and the BDNF expression were investigated in injured hemisphere section from immunohistochemistry using light microscope. Result : Immunohistochemical response of BDNF in lateral nucleus, purkinje cell layer, superior vestibular nucleus and pontine nucleus appeared very higher in group II than in group I Conclusion : The present result revealed that simultaneously application of balance training for proprioceptive and vestibular sensory stimulation input and therapeutic environment in traumatic brain injured rats is enhance expression of BDNF and it is facilitates neural plasticity.

• Applied Microscopy
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• v.48 no.4
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• pp.102-109
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• 2018

Multiple synaptic boutons (MSBs) have been reported to be synapse with two or more postsynaptic terminals in one presynaptic terminal. These MSBs are known to be increased by various brain stimuli. In the motor cortex, increased number of MSB was observed in both acrobat training (AC) model and traumatic brain injury (TBI) model. Interestingly one is a physiological stimuli and the other is pathological insult. The purpose of this study is to compare the connectivity of MSBs between AC model and TBI model in the cerebral motor cortex, based on the hypothesis that the connectivity of MSBs might be different according to the models. The motor cortex was dissected from perfused brain of each experimental animal, the samples were prepared for routine transmission electron microscopy. The 60~70 serial sections were mounted on the one-hole grid and MSB was analyzed. The 3-dimensional analysis revealed that 94% of MSBs found in AC model synapse two postsynaptic spines from same dendrite. But, 28% MSBs from TBI models synapse two postsynaptic spines from different dendrite. This imply that the MSBs observed in motor cortex of AC model and TBI model might have different circuits for the processing the information.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.11 no.2
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• pp.13-26
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• 2007

Background: Neurofeedback is an electroencephalographic biofeedback technique for training individuals to alter their brain activity via operant conditioning. Also neurofeedback is a form of behavioural training aimed at developing skills for brain activity. Within the past decade, several neurofeedback studies have been published that tend to overcome the methodological shortcomings of earlier studies. This research describes the methodical basis of neurofeedback and reviews the evidence base for its clinical efficacy and effectiveness in attention-deficit hyperactivity disorder (ADHD). Methods: In neurofeedback training, self-regulation of specific aspects of electrical brain activity is acquired by means of immediate feedback and positive reinforcement. In frequency training, activity in different EEG frequency bands has to be decreased or increased. Slow cortical potentials (SCPs) training is focused on the regulation of cortical excitability. Results: Neurofeedback studies revealed training-specific effects on, for example, attention and memory processes and performance improvements in real-life conditions, in healthy subjects as well as in patients. In several studies it was shown that ADHD symptomatology was reduced after frequency training or SCP(Slow cortical potentials) training. Moreover a decrease of impulsivity errors and an increase of the contingent negative variation. Conclusions: This research provides evidence for both positive behavioural and specific neurophysiological effects of neurofeedback training. Also there is growing evidence for neurofeedback as a valuable module in neuropsychiatric disorders. Further, controlled studies are warranted.

• The Journal of Korean Academy of Sensory Integration
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• v.20 no.1
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• pp.14-25
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• 2022

Objective : The purpose of this study was to investigate the effect of brain-timing training using an Interactive Metronome (IM) on the reading abilities of children with low brain-timing abilities. Methods : A single-group pretest and posttest (retrospective study) were conducted in 8 children whose timing abilities were lower than that for their age average and who were trained from 2019 to 2021. Brain-timing training was conducted 2 or 3 times per week, with 70 sessions in total and 40-50 minutes per session, depending on the developmental characteristics of the child. Changes in brain-timing ability before and after the training were measured using the IM Long-Form Assessment (LFA), and reading ability was measured using the Basic Academic Skills Assessment:Reading (BASA:R). Results : On the basis of the results of the brain-timing ability evaluation using the LFA, the reaction times of all the children during motor tasks were decreased, resulting in statistically significant improvements in their brain-timing abilities (p < .05). Moreover, the raw scores in the BASA:R reading and fill-in-the-blank tests were significantly improved (p < .05). Conclusion : This study is meaningful in that it presents a clinical basis for brain-timing training to improve the reading abilities of children.

• Child Health Nursing Research
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• v.14 no.3
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• pp.315-324
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• 2008

Purpose: This study was done to determine the effects of a neurofeedback program on brain function and stress in occupational high school students. Method: A nonequivalent control group, non-synchronized with pre-posttest design was used with 62 students. Data collection was done from July to December, 2007. The neurofeedback training was given for 30 minutes at a time, three times a week for 12 weeks. Brain function was measured by brain waves in the frontal lobes of the students and analyzed by eight brain quotients characterizing patterns of EEG rhythms. The instrument used to measure stress was a scale for stress from regular daily life. Results: After neurofeedback training, the level of brain quotients in students in the experiment group increased(t=2.36, p<.05) and the level of stress decreased(t=-3.59, p<.001). Conclusion: The results of the study suggested that a neurofeedback program is effective for brain function improvement and stress reduction in high school students. Therefore, the conclusion of this study is that neurofeedback programs can be useful to increase brain function and decrease stress in occupational high school students.

• Journal of the Korean Society of Physical Medicine
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• v.13 no.4
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• pp.59-65
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• 2018

PURPOSE: The purpose of the present study is to investigate the changes in the cognitive function of elderly dementia patients residing in a residential care facility, following six weeks of brain-computer interface (BCI)-based cognitive training and to determine whether BCI-based cognitive training effectively improves their cognitive functions. METHODS: Thirty subjects diagnosed with dementia were randomly assigned to either the experimental or control group. Pre- and post-test cognitive function assessments were conducted using the mini mental state examination-Korean (MMSE-K) and Korean-dementia rating scale (K-DRS). The experimental group received BCI-based cognitive training, which consisted of games such as flying a ball and exploding a bomb, while the control group participated in music listening activities and National Health Gymnastics. Both groups engaged in a total of 18 sessions (3 times per week for 6 weeks, for 40 minutes per session). RESULTS: After 6 weeks of intervention, the experimental group had significantly increased MMSE-K scores ($19.53{\pm}1.30$ to $22.20{\pm}1.15$; p<.0011) and total K-DRS scores ($87.20{\pm}4.16$ to $99.33{\pm}1.15$; p<.0011). In addition, the experimental group showed greater cognitive improvements than the control group. CONCLUSION: The results of this study suggest that BCI-based cognitive training is a positive intervention tool for improving the cognitive function of dementia patients.

• International Journal of Advanced Culture Technology
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• v.10 no.4
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• pp.286-293
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• 2022

In this study, we extracted sound waves that can improve psychological skills for volleyball players, investigated the changes that the application training of the extracted sound waves has on the brain waves of volleyball players, and the changes in brain waves are the psychological of volleyball players. The purpose of the research is to investigate the effect on technology. In order to achieve this purpose of the study, a total of 10 people from the experimental group and 10 from the control group were selected as the research subjects of university volleyball players with more than 5 years of volleyball experience. The experimental procedure was for the experimental group to listen to sound waves for more than 30 minutes at least 4 times a week for 12 weeks, and brain waves were measured 3 times before, during, and after. In addition, psychological skills were measured twice before and after. The measured data were subjected to t-test and two-way variance repeated measures analysis using SPSS 20.0. The results obtained through this process are as follows. First, as a result of analyzing the differences in psychological skills according to sound wave application training, there were statistically significant differences in goal setting and attention factors of the experimental group. Second, as a result of repeated measurement variance analysis at each time point according to the application of the sound wave application training program, it was found that alpha waves had a synergistic effect at the statistical significance level in the experimental group. Third, as a result of repeated measurement variance analysis at each time point according to the application of the sound wave application training program, it was found that the beta wave had a synergistic effect at the statistical significance level in the experimental group.

• Journal of The Korean Society of Integrative Medicine
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• v.3 no.4
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• pp.11-21
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• 2015

Purpose : The purpose of this study was to provide the material about the treatment effect of hand function training and writing training being performed as a part of treatment to improve the function of the non-dominant hand of the patients whose dominant hand is damaged and thus need to improve their non-dominant hand's function. Method : During one month of November, 2013, this study randomly chose five study subjects for hand function training, five for writing training, and ten of control group from 20 normal male and female adults going to K Univ. in Busan. All study subjects fully understood all of the training course, agreed to take the test in this study, and volunteered to participate in the test. Each training was performed five times for two weeks, 30 minutes each time. For measurement, Purdue pegboard was used to look into the change of hand dexterity. To investigate an improvement in hand function through hand function training and writing training, this study conducted early evaluation before training, interim evaluation, and final evaluation. Result : First, according to the comparison of dominant hand dexterity by group and by method during a training period, the groups of hand function training and of writing training improved dominant hand dexterity more than the control group. Secondly, according to the comparison of non-dominant hand dexterity by group during a training period, the groups of hand function training and of writing training improved dexterity more than the control group. According to the comparison of non-dominant hand dexterity by method during a training period, there was no big difference in dexterity between the groups of hand function training and of writing training and the control group. But, the group of hand function training showed a further improvement. Thirdly, according to the comparison of both-hand dexterity by group and by method during a training period, the groups of hand function training and of writing training improved both-hand dexterity more than the control group. Fourthly, according to the comparison of both-hand handling ability by group and by method during a training period, the groups of hand function training and of writing training improved both-hand handling ability more than the control group. Conclusion : Given the study result, it is considered that hand function training and writing training help brain damaged patients improve their hand function for their daily activity. And it will be meaningful to research brain damaged patients' motor skills after their brain damage, and the patients who have low abilities of visual perception and cognition. In the future, it will be necessary to secure more study subjects and perform systematic training during a sufficient test period.

• PNF and Movement
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• v.20 no.2
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• pp.235-241
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• 2022

Purpose: The purpose of this study was to identify the effects of low intensity blood flow restriction training (LBFR) on the central nervous system of healthy adults. Methods: Ten healthy right-handed adults (eight males and two females, mean age of 28.6 ± 2.87 years) were selected as study subjects. Functional magnetic resonance imaging (fMRI) was conducted to measure brain activation (BA) following LBFR and non-LBFR. The primary motor area, premotor area, and supplementary motor area, which are closely related to exercise, were set as the regions of interest. Results: The BA recorded during the LBFR condition was 931.7 ± 302.44 voxel, and the BA recorded during the non-LBFR condition was 1,510.9 ± 353.47 voxel. Conclusion: BA was lower during LBFR than during non-LBFR.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.28 no.2
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• pp.115-122
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• 2017

Objectives: Executive dysfunctions including working memory deficit have been suggested to be one of the major neuropsychological etiologies of attention-deficit hyperactivity disorder (ADHD). The purpose of this study was to investigate the augmentative effects of working memory training on the behavioral problems, quality of life, and parental stress of medicated children with ADHD. Methods: Twenty-five children with ADHD, aged 9 to 19 years, who were being treated with ADHD medication, were included. The participants were trained with a commercially available and computerized working memory program ($Cogmed^{(R)}$) for 5 weeks without any alteration of their medication. The Child Behavior Checklist (CBCL), KIDSCREEN-52 quality of life measure, and Parenting Stress Index-Short Form (PSI-SF) were administered before training, and 4 weeks and 7 months after training, respectively. Results: After completing the training, the anxiety/depression, social problems, thought problems, attention problems, aggressive behavior, and externalizing problems scores in the CBCL were significantly reduced. The score on the Parent-child dysfunctional interaction in the PSI-SF was also decreased. However, the scores related to the quality of life were not changed. These changes were still observed 7 months after the training. Conclusion: Cogmed working memory training can be a promising training option for the additional improvement of behavioral problems and parental stress in medicated children with ADHD.