• 대한간호학회지
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• 제29권6호
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• pp.1244-1253
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• 1999

The purpose of this study was to explore and describe the experience of Dan-Jeon breathing training and of Qi as a essential substance in forming human body. The sample consists of 7 participants who are Dan-Jeon Breathing training in a Training center, Pusan, Korea. They were asked open-ended questions in order for them to talk about their experiences. With permission of the subjects, the interviews were recorded and transcribed. The summarized results of this research are following. 1. The purpose of Dan-Jeon Breathing The interview data was organized by themes into 4 categories : hope for health recovery, a concern about Dan-Jeon Breathing, seeking meaning of life, change of lifestyle 2. The experience of Qi during Dan-Jeon Breathing training The interview data was organized by themes into 3 categories : an autonomic movement of body, spiritual experience, conviction of existence of Qi. 3. The change after Dan-Jeon Breathing training. The interview data was organized by themes into 7 categories : physical health promotion, emotional relaxation, promoting brain function, positive attitude about life, love to others, investigation for self, improvement on Qi feeling..

• Journal of Audiology & Otology
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• 제25권1호
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• pp.22-26
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• 2021

Background and Objectives: Music listening has a concomitant effect on structural and functional organization of the brain. It helps in relaxation, mind training and neural strengthening. In relation to it, the present study was aimed to find the effect of Carnatic music listening training (MLT) on speech in noise performance in adults. Subjects and Methods: A total of 28 participants (40-70 years) were recruited in the study. Based on randomized control trial, they were divided into intervention and control group. Intervention group underwent a short-term MLT. Quick Speech-in-Noise in Kannada was used as an outcome measure. Results: Results were analysed using mixed method analysis of variance (ANOVA) and repeated measures ANOVA. There was a significant difference between intervention and control group post MLT. The results of the second continuum revealed no statistically significant difference between post training and follow-up scores in both the groups. Conclusions: In conclusion short-term MLT resulted in betterment of speech in noise performance. MLT can be hence used as a viable tool in formal auditory training for better prognosis.

• 대한청각학회지
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• 제25권1호
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• pp.22-26
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• 2021

Background and Objectives: Music listening has a concomitant effect on structural and functional organization of the brain. It helps in relaxation, mind training and neural strengthening. In relation to it, the present study was aimed to find the effect of Carnatic music listening training (MLT) on speech in noise performance in adults. Subjects and Methods: A total of 28 participants (40-70 years) were recruited in the study. Based on randomized control trial, they were divided into intervention and control group. Intervention group underwent a short-term MLT. Quick Speech-in-Noise in Kannada was used as an outcome measure. Results: Results were analysed using mixed method analysis of variance (ANOVA) and repeated measures ANOVA. There was a significant difference between intervention and control group post MLT. The results of the second continuum revealed no statistically significant difference between post training and follow-up scores in both the groups. Conclusions: In conclusion short-term MLT resulted in betterment of speech in noise performance. MLT can be hence used as a viable tool in formal auditory training for better prognosis.

• Journal of Korean Neurosurgical Society
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• 제58권1호
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• pp.14-21
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• 2015

Objective : To study the effect of early intervention and rehabilitation in the expression of aquaporin-4 and ultrastructure changes on cerebral palsy pups model induced by intrauterine infection. Methods : 20 pregnant Wistar rats were consecutively injected with lipopolysaccharide intraperitoneally. 60 Pups born from lipopolysaccharide group were randomly divided into intervention group (n=30) and non-intervention group (n=30); intervention group further divided into early intervention and rehabilitation group (n=10), acupuncture group (n=10) and consolidate group (n=10). Another 5 pregnant rats were injected with normal saline intraperitoneally; 30 pups born from the normal saline group were taken as control group. The intervention group received early intervention, rehabilitation and acupuncture treatment. The motor functions of all pups were assessed via suspension test and modified BBB locomotor score. Aquaporin-4 expression in brain tissue was studied through immunohistochemical and western-blot analysis. Ultrastructure changes in damaged brain and control group were studied electron-microscopically. Results : The scores of suspension test and modified BBB locomotor test were significantly higher in the control group than the intervention and non intervention group (p<0.01); higher in the intervention group than the non-intervention group (p<0.01). The expression of Aquaporin-4 was lower in intervention and non intervention group than in the control group (p<0.01); also lower in non-intervention group than the intervention group (p<0.01). Marked changes were observed in ultrastructure of cortex and hippocampus CAI in brain damaged group. Conclusion : Early intervention and rehabilitation training can improve the motor function in offspring with brain injury and reduce the expression of aquaporin-4 in damaged brain.

• 대한의용생체공학회:의공학회지
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• 제28권5호
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• pp.657-664
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• 2007

Stroke patients need regular medical treatments and rehabilitation training from their doctors. However, severe aftereffects caused by stroke allow them minimum activities, which make it difficult for them to visit doctor. Recently, electric brain stimulation treatment has been found to be better way compared to conventional ones and many are interested in using this method for the treatment of stroke. In this study, we have developed a remote medical treatment system using wireless electric brain stimulator that can help the stroke patients to get a treatment without visiting their doctors. The developed remote medical treatment system connects the doctors to the brain stimulator implanted in the patients via the internet and ZigBee communication built in the brain stimulator. Also, the system receives personal information of the connected patients and cumulates the total records of electric stimulation therapy in a database. Doctors can easily access the information for better treatment planning with the help of graphical visualization tools and management software. The developed remote medical treatment system can be applied to the electric stimulation treatments for other brain diseases with a minor change.

• 한국산학기술학회논문지
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• 제12권6호
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• pp.2548-2553
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• 2011

이 연구는 뉴로피드백 훈련을 통하여 유아들의 습득도에 미치는 영향을 개인이 지닌 뇌신경 생리학적 지표인 뇌파 측정을 이용하여 연구 하여 보았다. 대상자는 2010년 3월에서 2010년 11월까지 S시 W 유치원 원아 52명(실험군 26명, 대조군 26명)을 기준으로 선정한 자료이다. 훈련 전과 후의 뇌기능 변화는 시계열 선형 분석을 통하여 비교하였으며 연구 검증 결과. 뉴로피드백 훈련을 적용한 원아들에서 뇌기능과 습득도 척도에서 유의미한 차이를 보였다. 이 결과는 전전두엽 뉴로피드백 훈련이 유아들의 뇌기능의 발달과 습득도에 긍정적인 영향을 미쳤다고 본다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제14권3호
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• pp.962-975
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• 2020

The accurate segmentation of infant brain MR image into white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF) is very important for early studying of brain growing patterns and morphological changes in neurodevelopmental disorders. Because of inherent myelination and maturation process, the WM and GM of babies (between 6 and 9 months of age) exhibit similar intensity levels in both T1-weighted (T1w) and T2-weighted (T2w) MR images in the isointense phase, which makes brain tissue segmentation very difficult. We propose a deep network architecture based on U-Net, called Triple Residual Multiscale Fully Convolutional Network (TRMFCN), whose structure exists three gates of input and inserts two blocks: residual multiscale block and concatenate block. We solved some difficulties and completed the segmentation task with the model. Our model outperforms the U-Net and some cutting-edge deep networks based on U-Net in evaluation of WM, GM and CSF. The data set we used for training and testing comes from iSeg-2017 challenge (http://iseg2017.web.unc.edu).

• International Journal of Internet, Broadcasting and Communication
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• 제15권2호
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• pp.124-132
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• 2023

In this paper, we present a simple classification model based on statistical features and demonstrate the successful implementation of a brain-computer interface (BCI) based light on/off control system. This research shows study and development of light on/off control system based on BCI technology, which allows the users to control switching a lamp using electroencephalogram (EEG) signals. The logistic regression algorithm is used for classification of the EEG signal to convert it into light on, light off control commands. Training data were collected using 14-channel BCI system which records the brain signals of participants watching a screen with flickering lights and saves the data into .csv file for future analysis. After extracting a number of features from the data and performing classification using logistic regression, we created commands to switch on a physical lamp and tested it in a real environment. Logistic regression allowed us to quite accurately classify the EEG signals based on the user's mental state and we were able to classify the EEG signals with 82.5% accuracy, producing reliable commands for turning on and off the light.

• 재활복지공학회논문지
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• 제11권3호
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• pp.253-259
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• 2017

현재 뇌손상환자에게 시행되고 있는 재활치료들은 훈련 환경이 단조롭고 긴 시간 동안 단순하고 반복적인 운동으로 인해 흥미와 참여도가 떨어져 훈련 효율이 저하된다는 문제가 제기되었다. 이와 같은 문제를 해결하기 위해 본 논문에서는 상지 재활훈련을 위해 상지에서 측정되는 근전도 신호와 모션센서를 기반으로 하는 웨어러블 장치와 모바일 게임을 결합한 새로운 재활 프로그램 개발을 제안함으로 위에서 제기된 문제를 해결하고자 하였다. 개발된 웨어러블 장치는 밴드 형태로 제작되어 신체에 쉽게 착용 및 해체가 가능하고, 모바일 게임은 웨어러블 장치로부터 측정되는 근전도 신호를 통하여 인식되는 움켜잡는 행동(grasp motion)과 모션센서를 통하여 인식되는 굴곡(flexion), 신전(extension), 외전(abduction), 내전(adduction)을 반영하여 게임을 통한 재활훈련이 가능하도록 설계되었으며, 난이도 조절을 통한 환자 개개인에 적합한 맞춤형 재활환경을 제공할 수 있도록 하였다. 개발된 프로그램을 상지 재활이 필요한 14명의 뇌손상 환자를 대상으로 적용한 후, 설문조사를 통한 유용성 평가를 진행한 결과 개발된 재활프로그램이 기존 재활프로그램보다 흥미가 있었고 재활훈련 간 지루하지 않았다고 응답하였고, 추후 개발된 프로그램 재사용에 대한 의지를 보였다.

• Parasites, Hosts and Diseases
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• 제48권1호
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• pp.15-21
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• 2010

Astrocytes are the most abundant cells in the central nervous system that play roles in maintaining the blood-brain-barrier and in neural injury, including cerebral malaria, a severe complication of Plasmodium falciparum infection. Prostaglandin (PG) $D_2$ is abundantly produced in the brain and regulates the sleep response. Moreover, $PGD_2$ is a potential factor derived from P. falciparum within erythrocytes. Heme oxygenase-1 (HO-1) is catalyzing enzyme in heme breakdown process to release iron, carbon monoxide, and biliverdin/bilirubin, and may influence iron supply to the P. falciparum parasites. Here, we showed that treatment of a human astrocyte cell line, CCF-STTG1, with $PGD_2$ significantly increased the expression levels of HO-1 mRNA by RT-PCR. Western blot analysis showed that $PGD_2$ treatment increased the level of HO-1 protein, in a dose- and time-dependent manner. Thus, $PGD_2$ may be involved in the pathogenesis of cerebral malaria by inducing HO-1 expression in malaria patients.