• 대한골관절종양학회지
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• 제9권1호
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• pp.69-76
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• 2003

목적: 족부에 발생하는 종양의 임상적 특성과 병리학적 특성 및 분포 등을 조사하여, 족부 종양을 진단하고 치료하는데 기초 자료를 제공하고자 한다. 대상 및 방법: 족부 종양 환자 141명의 142 종양을 대상으로 하였다. 대상환자들은 모두 조직검사를 통하여 진단이 된 환자들이었다. 대상이 되었던 환자들의 의무기록과 영상 검사들을 후향적으로 검토하여 종양의 역학적 조사와, 임상적 특성과 수술의 방법을 확인하였고, 병리학적 특성을 조사하였다. 종양이 발생 위치는 Kirby 등이 제안한 구역(zone)에 따라 분류하였다. 결과: 여자는 75명이었고 남자는 66명으로 여자가 조금 많았다. 전체 환자들의 평균 나이는 33.2세였다. 양성 연부조직 종양이 68예로 가장 많았고, 양성 골종양이 57예, 악성 연부조직 종양이 12예, 악성 골종양이 5예의 순이었다. 양성 연부조직 종양 중에는 결절종이 36예로 가장 많았고, 양성 골종양 중에서는 조갑하 외골종이 18예, 악성 연부조직 종양 중에서는 편평 상피 세포암이 7예, 악성 골종양으로는 폐암의 전이 병소가 2예였다. 환자들의 임상 증상으로 통증은 악성 골종양 환자들이 가장 높은 비율로 호소하였고, 증상 발현 기간은 양성 연부조직 종양이 가장 길었고, 신경학적 증상은 양성 연부조직 종양에서만 3예가 있었다. 종양의 평균 크기는 악성 골종양이 가장 크고, 양성 골종양이 가장 작았다. 구역별 분포는 전체적으로 5 구역에 59예로 가장 많았고, 4 구역에 10예로 가장 적었으며, 양성 골종양에서는 5 구역, 양성 연부조직 종양에서는 1 구역, 악성 골종양에서는 1, 2 구역, 악성 연부조직 종양에서는 5 구역에서 가장 많았다. 수술 방법으로 병소내 혹은 변연부 절제술, 소파술 혹은 소파술 및 골이식 수술, 족지 절단수술, 슬관절 하 절단술과 사지구제술 등이 있었다. 결론: 족부에 발생하는 종양은 드물고 종류가 다양하면서 대부분(88%) 양성 종양이었으나, 진단 과정에서 환자의 나이, 통증 유무, 증상 발현 기간, 종양의 크기 및 발생 구역 등을 고려하여 악성 종양의 가능성을 배제하지 않음으로써 올바른 치료를 할 수 있을 것으로 사료된다.

• 대한족부족관절학회지
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• 제11권1호
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• pp.1-7
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• 2007

Purpose: Tumors arising in the foot and ankle are uncommon and the malignant tumors are known to be rare compared with those of the other sites. We analyzed the clinical data of patients who have been diagnosed as having a tumor of the foot and ankle. Materials and Methods: From 1989 to 2006, we analyzed 185 patients who have been treated surgically and were pathologically confirmed of having tumors of the foot and ankle. Their clinical characteristics were reviewed retrospectively. Results: One hundred and fifty-seven cases were benign (84.9%) and 28 cases (15.1%) were malignant. 108 cases (58.4%) were benign soft tissue tumors and 49 cases (26.5%) were benign bone tumors. Malignant tumors included 17 cases (9.2%) of soft tissue tumors, 8 cases (4.3%) of primary bone tumors and 3 cases (1.6%) of metastatic bone tumors. The most common benign soft tissue tumor was ganglion (23 cases). Enchondroma (9 cases) was the most common among the benign bone tumors. Malignant peripheral nerve sheath tumor was the most common malignant tumor (4 cases). The predilection site for benign tumors was at the forefoot around toes while for the malignant tumor was around the ankle. 4.6% of benign soft tissue tumors and 8.2% of benign bone tumors had locally recurred and 14 cases (50%) of malignant tumor were confirmed as having distant metastasis. Conclusion: The ratio of malignant tumor and its metastasis rate was high. Therefore, the histopathologic confirmation is essential when treating tumors of the foot and ankle.

• 대한족부족관절학회지
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• 제5권1호
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• pp.82-85
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• 2001

We experienced a case of soft tissue osteochondroma in the foot. The 43-years-old male was complained palpable mass and mild pain at the heel for 3 years. The plain radiograpy revealed a bony mass without connection of neighbor bone in the heel. The osteochondroma in the soft tissue is rare benign tumor. The mass was removed en bloc. The gross and histologic findings were consistent with osteochondroma. The differential diagnosis includes myositis ossificans, tumoral calcinosis, synovial chondromatosis, soft tissue osteochondroma, and true osteochondroma which arises from bone. The symptom was improved. After postoperative 1 year, recurrence was not.

• 대한골관절종양학회지
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• 제2권1호
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• pp.33-37
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• 1996

From January 1994 to August 1995 we performed 270 cases of fine needle aspiration cytology for bone and soft tissue lesions. Among them 137 cases were diagnosed histologically. Sixty-seven cases were benign and 70 cases were malignant. We analysed these on the aspect of sensitivity, specifity, positive predictive value, negative predictive value of the cytologic examination. Malignant cases consisted of bone tumor 29 cases; soft tissue tumor 25 cases; and metastatic tumor 16 cases. The sensitivity and specifity of the aspiration cytology for malignant tumor were 67.8% and 97%, respectively. The positive and negative predictive value of aspiration cytology were 97.4% and 72.7%, respectively. Among them 40 cases were primary bony lesions; 14 benign lesions, 26 malignamt bone tumors. Sensitivity of aspiration cytology for these primary bony lesion was 90%(18/20) and its specifity was 100%(13/13). Three cases showed atypical cells in cytology but with biopsy we could find them as one benign and two malignancies. Two cases of manignancy showed negative result in cytology; one was parosteal sarcoma of proximal femur and the other was osteosarcoma of proximal tibia which was biopsied already at other hospital. Although the overall sensitivity and specifity for malignant bone and soft tissue tumors were relatively low and not so predictable, the fine needle aspiration cytology for primary bony lesion was useful in the differential diagnosis of benign or malignancy.

• 치과방사선
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• 제19권1호
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• pp.137-147
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• 1989

CT findings of proven 25 malignant tumors of the maxillary sinus were retrospectively analyzed to be of help in the diagnosis and treatment. The results were follows: 1. Average age was 54 years old, and eighteen were males and seven were females with a ratio of 2.6:1 2. The most common histopathologic feature was squamous cell carcinoma (19 cases) and others were two cases of adenoid cystic carcinoma, one case of malignant fibrous histiocytoma, mucoepidermoid tumor, histiocytic lymphoma, unidentified malignant tumor. 3. CT findings were sinus opacificaqtion (4%), soft tissue mass (92%), low densities within soft tissue mass (44.%), air densities within soft tissue mass (24%), osteosclerosis (4%), bone destruction (92%), bone displacement (32%), fat plane obliteration (76%). 4. CT in the malignant maxillary sinus tumors approved the value in evaluation of tumor extension to nasal cavity, ethmoid sinus, orbit, infratemporal fossa, pterygopalatine fossa, pterygoid fossa, pterygoid muscle, cheek skin and intracranial cavity. 5. Twenty four cases (96%) were stage Ⅲ, stage Ⅳ according to AJCC TNM classification. 6. Bone findings were destruction, displacement, sclerosis and most frequent site of bone destruction was the medial wall of the antrum(92%). 7. Tumor growth pattern showed destructive pattern in 18 cases(72%), and squamous cell carcinoma showed destructive pattern. (P<0.05)

• Journal of Chest Surgery
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• 제40권7호
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• pp.526-528
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• 2007

골조직에 발생하는 거대세포종은 국소적으로는 양성이지만 재발률이 매우 높고, 아주 드물게 원격전이를 일으킬 수 있다. 우측 요골에 발생한 거대세포종이 치료 후 재발되어, 요골을 제거한 후, 다시 동측 흉벽 연부조직에 전이된 29세의 남자환자를 보고하는 바이다. 종양은 흉벽의 골조직과는 연관이 없었다. 수술은 주위 연부조직과 함께 광범위 절제하였으며, 조직학적 검사상 악성 종양을 시사하는 소견은 없었다.

• 대한골관절종양학회지
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• 제1권2호
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• pp.210-219
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• 1995

Many different factors which may affect the prognosis of the soft tissue sarcomas have been reported by many authors ; Generally, tumor size, histologic type, surgical margin, and multi modality therapy therapy as the prognostic factors were reported. The objectives of this retrospective study of soft tissue sarcomas are : 1) to define more clearly prognostic variables that have significant predictive value for disease-free and overall survival ; and 2) to evaluate tumor histologic grade based upon extent of tumor necrosis as a means of stratifying more aggressive soft tissue sarcomas(grade II & III) of the extremities. We treated 94 patients who had soft tissue sarcoma of the extremities and trunk from May 1984 to September 1994(average duration of follow-up was 5 years ranging from 2 months to 10 years) and evaluated the prognostic factors of the soft tissue sarcomas; age, sex, depth, size, location, histologic type and grade, stage, therapy modality, surgical margin, local recurrence and distant metastasis. The results were as follows. 1. The patients with poorer prognosis were over the age of fifty, whose mass was deeply located, size of the mass was over 10cm in diameter, grade III in histology, who had local recurrence, metastasis, and received only surgery. 2. Among these prognostic factors, the most significant prognostic factor was histologic grade base upon extent of tumor necrosis.

• Nuclear Medicine and Molecular Imaging
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• 제41권6호
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• pp.553-560
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• 2007

목적: F-18 FDG PET은 근골격계 종양에서 양성과 악성병변을 감별하는 유용성에 대하여 다양한 결과가 보고되고 있다. 저자들은 F-18 FDG를 이용한 PET/CT로 근골격계 종양의 maxSUV를 분석하고 비교하여 유용성을 알아보았다. 대상 및 방법: 치료 전 46개 병소(연부 조직 종양 양성/악성 : 11/12, 골종양 양성/악성 9/14)에 대하여 F-18 FDG PET/CT를 시행하였으며, 조직학적 검사로 확진하였다. 악성과 양성을 구분하는 maxSUV 절단값은 연부 조직 종양에서는 4.1, 골종양에서는 3.05로 하였다. 결과: 연부 조직 종양에서 양성(R=11; maxSUV $3.4{\pm}3.2$)과 악성(n=12; maxSUV $14.8{\pm}12.2$) 간에 maxSUV는 통계학적으로 유의하게 (p<0.001) 차이가 있었다. 민감도와 특이도는 각각 83%, 91%였다. 그러나 골종양에서는 양성 종양(n=9; maxSUV $5.4{\pm}4.0$)과 악성 골종양(n=14; maxSUV $7.3{\pm}3.2$) 간에 통계학적으로 유의한 차이를 보이지 않았다. 연부 조직 종양에서는 결절성 근막염이 위양성으로 나타났고(maxSUV=12.4) 골종양에서는 섬유성 골이형성증과 랑게르한스세포 조직구증식증 2예 및 골모세포종이 있었다. 결론: 연부 조직 종양에서 maxSUV는 양성과 악성을 감별하는데 유용하였다. 그러나 골종양의 경우에는 maxSUV가 낮은 경우에는 악성을 배제할 수 있었으나, maxSUV가 높은 경우에는 조직학적으로 조직구나 섬유모세포 등이 포함된 종양의 감별진단을 고려하여야한다.

• 대한두개안면성형외과학회지
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• 제22권5호
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• pp.276-279
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• 2021

A 65-year-old woman presented with a solid mass on the right temporal area. The mass had grown for over 2 years without any initiating event of trauma or inflammation. Before excision, the patient went through a computed tomography scan, revealing a calcified mass without bony connection. Under general anesthesia, an excisional biopsy was performed. Microscopic examination confirmed a diagnosis of soft tissue osteoma. Soft tissue osteoma is rare, especially in the head and neck region. Osteomas in the temporal region have not been reported yet. Due to its rarity, osteoma might be misdiagnosed as another soft tissue or bone origin tumor. Its treatment of choice is simple excision. In this review, we present an unusual clinical form of soft tissue osteoma.

• 대한골관절종양학회지
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• 제1권1호
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• pp.105-112
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• 1995

Soft tissue sarcomas are malignant tumors that arise in the extraskeletal connective tissues of the body. And the clinical behavior of soft tissue sarcomas is characterized by a tendency to extensively invade surrounding soft tissues as well as early metastatic dissemination. Difficulties were encounted when soft tissue sarcomas invade the major vessels. There are a few reprots about the reconstruction of the major vessels after resection of soft tissue sarcomas. We have treated 3 cases of the soft tissue sarcomas involving the major artery. After marginal excision of the tumor mass, the involved major artery was reconstructed with Gortex artificial vessel graft and we could salvage the patient's extremity.