• Korean Journal of Digital Imaging in Medicine
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• v.15 no.1
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• pp.33-38
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• 2013

Bone is so crucial anatomy for human body. Many researchers study deep into a subject about bone regeneration. There is no standard analysis for quantitative Neo-bone regeneration on calvarial defected model. Micro CT is so useful method to quantitative analysis of Neo-bone regeneration. This study was show that how to quantitative analysis of Neo-bone regeneration with ${\mu}-CT$ Micro CT was possible to quantitative analysis for Neo-bone regeneration on Calvarial defected model. futhermore Not only was Micro CT possible for qualitative analysis but quantitative analysis on the mouse calvarial model. This study will provide bone biology researchers with accurate quantitative analysis.

• The Journal of the Acoustical Society of Korea
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• v.29 no.2E
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• pp.64-72
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• 2010

Osteoporosis is a skeletal disease characterized by two factors: reduced bone mass and microstructure disruption of bone tissue. These symptoms increase bone fragility and can contribute to eventual fracture. In recent years, quantitative ultrasound (QUS) technologies have played a growing role in the diagnosis of osteoporosis. Most of the commercial bone sonometers measure speed of sound and/or broadband ultrasound attenuation at peripheral skeletal sites. However, QUS parameters are purely empirical measures that have not yet been firmly linked to physical parameters, such as bone strength or porosity, and the underlying physics for their variations in cancellous bone is not well understood yet. This paper reviews the QUS technologies for the diagnosis of osteoporosis and also addresses several theoretical models, such as the Biot model, the scattering model, the stratified model, and the modified Biot-Attenborough model, for ultrasonic wave propagation in bone.

• The Journal of the Acoustical Society of Korea
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• v.27 no.2E
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• pp.45-50
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• 2008

In recent years, quantitative ultrasound (QUS) technologies have played a growing role in the diagnosis of osteoporosis. Most of the commercial bone somometers measure speed of sound (SOS) and/or broadband ultrasonic attenuation (EUA) at peripheral skeletal sites. However, the QUS parameters are purely empirical measures that have not yet been firmly linked to physical parameters such as bone strength or porosity. In the present study, the theoretical models for wave propagation in cancellous bone, such as the Biot model, the stratified model, and the modified Biot-Attenborough (MBA) model, were applied to predict the dependence of phase velocity on porosity in cancellous bone. The optimum values for the input parameters of the three models in cancellous bone were determined by comparing the predictions with the previously published measurements in human cancellous bone in vitro. This modeling effort is relevant to the use of QUS in the diagnosis of osteoporosis because SOS is negatively correlated to the fracture risk of bone, and also advances our understanding of the relationship between phase velocity and porosity in cancellous bone.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2002.10a
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• pp.1081-1084
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• 2002

In this study, we perform 3-D reconstruction of human proximal femur from DICOM files by using voxel mesh algorithm. After 3-D reconstruction, the model converted to Finite Element model which developed for automatically making not only 3-D geometrical model but also FE model from medical image dataset. During this job, trabecular pattern, one of characteristic of human bone can be added to the model by means of giving it's own elastic property calculated from intensity in CT scanned image to the each voxel. And then another model is made from same image dataset which have two material properties - one corresponds to cortical bone, another to trabecular bone. Finally, validity of voxel mesh technique is verified through comparing results of FE analysis, free vibration and stress analysis.

• Journal of Dental Rehabilitation and Applied Science
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• v.23 no.1
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• pp.69-78
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• 2007

This study was performed to compare the stress distribution pattern in the crestal cortical bone and cancellous bone using 3-dimensional finite element stress analysis when 2 different Young's modulus(high modulus, model 1; low modulus, model 2) of cancellous bone was assumed. For the analysis, a finite element model was designed to have two square-threaded implants fused together and located at first and second molar area. Stress distribution was observed when vertical load of 200N was applied at several points on the occlusal surfaces of the implants, including central fossa, points 1.5mm, 2mm, 3mm and 3.5mm buccally away from central fossa. The results were as follows; 1. In both model, the maximum Von-Mises stress in the crestal cortical bone was greater when the load was applied at the central point, points 1.5mm and 2mm buccally away from central fossa than other cases. 2. In the cortical bone around first and second molar, model 2 showed greater Von-Mises stress than model 1. It is concluded that when the occlusal contact is afforded, the distribution of stress varies depending on the density of cancellous bone and the location of loading. More favorable stress distribution is expected when the contact load is applied within the diameter of fixtures.

• Journal of the Semiconductor & Display Technology
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• v.21 no.2
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• pp.68-73
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• 2022

In this study, we produced the surface defect detection model to automatically detect defect bone plates using a deep learning algorithm. Bone plates with a width and a length of 50 mm are most used for fracture treatment. Normal bone plates and defective bone plates were printed on the 3d printer. Normal bone plates and defective bone plates were photographed with 1,080 pixels using the webcam. The total quantity of collected images was 500. 300 images were used to learn the defect detection model. 200 images were used to test the defect detection model. The mAP(Mean Average Precision) method was used to evaluate the performance of the surface defect detection model. As the result of confirming the performance of the surface defect detection model, the detection accuracy was 96.3 %.

• Journal of Veterinary Clinics
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• v.35 no.3
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• pp.83-87
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• 2018

The aim of this study was to evaluate the biomechanical behavior of xenogenic bone plate system (equine bone) using a three-dimensional finite element ulna fracture model. The model was used to calculate the Von Mises stress (VMS) and stress distribution in fracture healing periods with metallic bone plate and xenogenic bone plate systems, which are installed while the canine patient is standing. Bone healing rate (BHR) (0%) and maximum VMS of the xenogenic plate was similar to the yield strength of equine bone (125 MPa). VMS at the ulna and fracture zones were higher with the xenogenic bone plate than with the metallic bone plate at BHRs of 0% and 1%. Stress distributions in fracture zone were higher with the xenogenic bone plate than the metallic bone plate. This study results indicate that the xenogenic bone plate may be considered more beneficial for callus formation and bone healing than the metallic bon plate. Xeonogenic bone plate and screw applied in clinical treatment of canines may provide reduced stress shielding of fractures during healing.

• Journal of Biomedical Engineering Research
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• v.16 no.1
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• pp.25-32
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• 1995

Clinically, proximal bone resorption in the femur is frequently seen postoperatively on the follow up XI-rays after total hip replacement (THR). We developed the finite element model of cementless THR. The model is two dimensional side plate model, whereby the three dimensional structural integrity of the bone can be accounted for by a separate two dimensional mesh, a side plate. The subject of this article is the development and application of this two dimensional side plate FEM to study the reverse effect of the various degree of bone resorption of femur after THR. The results of this study indicates that 1) two dimensional side plate model is good and simple alternative to complex three dimensional model and 2) the severity of the proximal bone resorption has the effect of more increasing stress on the cortex at the level of femoral stem tip.

• Korean Journal of Radiology
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• v.24 no.11
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• pp.1151-1163
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• 2023

Objective: To develop a deep-learning-based bone age prediction model optimized for Korean children and adolescents and evaluate its feasibility by comparing it with a Greulich-Pyle-based deep-learning model. Materials and Methods: A convolutional neural network was trained to predict age according to the bone development shown on a hand radiograph (bone age) using 21036 hand radiographs of Korean children and adolescents without known bone development-affecting diseases/conditions obtained between 1998 and 2019 (median age [interquartile range {IQR}], 9 [7-12] years; male:female, 11794:9242) and their chronological ages as labels (Korean model). We constructed 2 separate external datasets consisting of Korean children and adolescents with healthy bone development (Institution 1: n = 343; median age [IQR], 10 [4-15] years; male: female, 183:160; Institution 2: n = 321; median age [IQR], 9 [5-14] years; male: female, 164:157) to test the model performance. The mean absolute error (MAE), root mean square error (RMSE), and proportions of bone age predictions within 6, 12, 18, and 24 months of the reference age (chronological age) were compared between the Korean model and a commercial model (VUNO Med-BoneAge version 1.1; VUNO) trained with Greulich-Pyle-based age as the label (GP-based model). Results: Compared with the GP-based model, the Korean model showed a lower RMSE (11.2 vs. 13.8 months; P = 0.004) and MAE (8.2 vs. 10.5 months; P = 0.002), a higher proportion of bone age predictions within 18 months of chronological age (88.3% vs. 82.2%; P = 0.031) for Institution 1, and a lower MAE (9.5 vs. 11.0 months; P = 0.022) and higher proportion of bone age predictions within 6 months (44.5% vs. 36.4%; P = 0.044) for Institution 2. Conclusion: The Korean model trained using the chronological ages of Korean children and adolescents without known bone development-affecting diseases/conditions as labels performed better in bone age assessment than the GP-based model in the Korean pediatric population. Further validation is required to confirm its accuracy.

• Journal of the Korean Society of Industry Convergence
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• v.22 no.4
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• pp.387-394
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• 2019

This paper presents an analytical study on the strength and stiffness of various types of truss structures. The applied models are triangular-like opened truss-wall triangular model (OTT), closed truss-wall triangular model (CTT), opened solid-wall triangular model (OST), and hypercube models defined as core-filled or core-spaced cube. The models are analyzed by numerical model analysis using DEFORM 2D/3D tool with AISI 304 stainless steel. Then, the ideal solutions for stiffness and strength are defined. Finally, the relative elastic modulus of the core-spaced model is obtained as 0.0009, which is correlated with the cancellous bone for the relative density range of 0.029-0.03, and the relative elastic modulus for the core-filled model is obtained as 0.0015, which is correlated with cancellous bone for the relative density range of 0.035-0.036. For the relative compressive yield strength, the OTT reasonably agrees with the cancellous bone for the relative density of 0.042 and the relative compressive strength of 0.05. The CTT and OST are in good agreement at the relative density of 0.013 and the relative compressive yield strength of 0.002. The hypercube models can be used for the cancellous bone for stiffness, and the triangular models can be used for the cancellous bone for strength. However, none of the models can be used to replace the compact bone because it requires much higher stiffness and strength. In the near future, compact bone replacement must be further studied. In addition, previously mentioned models should be developed further.