• Title/Summary/Keyword: Bolic acid

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Spectrophotometric Determination of Chlorpheniramine Maleate with Methyl Orange (메칠오렌지에 의한 말레인산클로르페니라민의 분광광도 정량)

  • Chun, In-Koo
    • Journal of Pharmaceutical Investigation
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    • v.16 no.4
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    • pp.139-147
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    • 1986
  • A singly charged methyl orange(MO) anion was found to be extracted with chlorpheniramine maleate(CPM) as a 1 : 1 complex in chloroform. Of various solvents, MO-chloroform system gave a yellow color for CPM, while in the absence of CPM, an organic phase showed almost no color. In this way, the spectrophotometric method was investigated for the determination of CPM by solvent extraction. The addition of alcoholic bolic acid solution to the solvent extract gave a higher color stability and transparency at least 5 days, but the extract alone lost its color intensity significantly. CPM is determined by measuring the absorbance of the extracts over a range of $1{\sim}7{\times}10^{-4}M\;(39{\sim}273\;{\mu}g/ml)$ in aqueous solution at 423 nm. The molar absorptivity was $2.26{\times}10^3\;l,\;mol^{-1},\;cm^{-1}$. The absorbance of the extract was constant in the range of pH $3.7{\sim}4.6$. This novel method was applied for the determination of CPM in artificial and commercial preparations in comparison with the analytical method of CPM tablets in K.P.IV. The results obtained showed that the former was better in accuracy and time consumption than the latter.

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Studies on Preparation of Boron Compounds from Colemanite Ore : Preparation of Boric Acid and Reaction Mechanism (I) (Colemanite 광물로부터 붕소화합물의 제조에 관한 연구 : 붕산제조 및 반응기구 (I))

  • Choi, Byung-Hyun;Lim, Hyung-Mi;Jee, Mi-Jung;Jang, Jae-Hun;Paik, Song-Hoo;Lee, Mi-Jai
    • Journal of the Korean Ceramic Society
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    • v.41 no.10 s.269
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    • pp.756-765
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    • 2004
  • We present extraction process and reaction mechanism of boric acid from one of calcium borate ores, colemanite by reaction with sulfuric acid. Colemanite has been fully decomposed under pH 5 with sufficiency amount of sulfuric acid, more than the amount stoichiometrically required. Calcium sulfate was separated out, leaving boron in the liquid phase after sulfuric acid addition. The extraction process of boric acid was affected by dissolution temperature and time, amount of sulfuric acid and ammonium sulfate, pH and a degree of concentration before recrystallization. The $SiO_2$ of the impurities which colemanite contains was insoluble so that it was separated out with calcium sulfate from liquid phase. The species of $CaO,\;Al_2O_3,\;Fe_2O_3,\;MgO$ were remained in a liquid phase after reaction with sulfuric acid. These impurities were separated out by addition of ammonia to the liquid phase, funhermore, boric acid was produced by process of pH adjustments and acidification, concentration, and recrystallization.

Factors Affecting Boron Deficiency Symptoms in Spring Grown Radishes(Raphanus sativus L.) (봄무우 붕소결핍증(硼素缺乏症)의 발생생리(發生生理)에 관(關)한 연구(硏究))

  • Hur, Il-Bong;Kim, Moo-Sung;Hwang, Son-Koo;Ryu, In-Soo
    • Korean Journal of Soil Science and Fertilizer
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    • v.16 no.1
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    • pp.72-76
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    • 1983
  • Absorption pattern and sensitivity of radishes to boron were compared with different boron treatment: soil application, foliar spray and no boron application. Six radish cultivars were planted on April 7 and harvested on June 23. Borax 1.5 Kg per 10 a was applied to soil before seeding and the 150 litters of 0.5 ppm solution with bolic acid was sprayed on leaves 3 times during the growing period. Boron content in plant was markedly increased by the soil application but no significant difference in boron contents in plants was observed between foliar spray and no application, presumably because of the insufficient dose of foliar spray. The darkening rot in root, a boron deficiency, was negligible in radishes grown in soil application plots whereas a relatively higher percentage of boron deficient plant was found from foliar spray or no application plots. The appearance of root darkening rot occurred at the rapid root enlargement stage, apparently from 55 days to 65 days after seeding. The boron contents in plants of soil application plots slightly increased at this stage while those of no boron application and foliar spray decreased. This obviously verified that boron deficiency should cause root rots showing highly significant relationship.

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