• Journal of Biomedical Engineering Research
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• v.22 no.4
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• pp.369-375
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• 2001

The statistical regression model is one of the most frequently used clinical analysis methods. It has basic assumption of linearity, additivity and normal distribution of data. However, most of biological data in medical field are nonlinear and unevenly distributed. To overcome the discrepancy between the basic assumption of statistical model and actual biological data, we propose a new analytical method based on artificial neural network. The newly developed multilayer perceptron(MLP) is trained with 120 data set (60 normal, 60 patient). On applying test data, it shows the discrimination power of 0.76. The diabetic risk factors were also identified from the MLP neural network model and the logistic regression model. The signigicant risk factors identified by MLP model were post prandial glucose level(PP2), sex(male), fasting blood sugar(FBS) level, age, SBP, AC and WHR. Those from the regression model are sex(male), PP2, age and FBS. The combined risk factors can be identified using the MLP model. Those are total cholesterol and body weight, which is consistent with the result of other clinical studies. From this experiment we have learned that MLP can be applied to the combined risk factor analysis of biological data which can not be provided by the conventional statistical method.

• Journal of the Korean Society of Clothing and Textiles
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• v.43 no.3
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• pp.416-426
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• 2019

This study measured and analyzed male firefighters hand sizes as well as suggested data for developing firefighting gloves with a good fit. Accordingly, body dimensions related to the hand were measured for 100 male firefighters. Twenty-three measuring items related to the hand and lower arm were selected. The firefighters' measurement data were compared to general adult male measurements from the 6th Korean Anthropometric data to analyze the hand sizes characteristics of firefighters. As a result, height, hand circumference, hand breadth, wrist circumference, elbow-wrist length, forearm-fingertip length and firefighter weight were significantly larger than adult males. A correlation analysis for 23 items was conducted to select items used as standards for setting a size when manufacturing firefighting gloves. Hand length and circumference were selected as representative hand parts for making firefighting gloves. Cross analysis between hand length and circumference were conducted to find the section showing the highest distribution ratio. As a result, the highest sections were between 19cm and 21cm for hand circumference and between 18.5cm and 19.5cm for hand length, which may be suggested as the most important ranges.

• Archives of Pharmacal Research
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• v.25 no.6
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• pp.946-953
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• 2002

Bisphenol A [2, 2 bis (4-hydoxyphenyl) propane; BPA] is a widely used endocrine disruptors and has estrogenic: activities. Although interests on biological effect of BPA are rising, evidences of its effect on immune system are lacking. We investigated that the effect of BPA on immune parameters to postulate the mechanism, and BPA interruptions between neuroendocrine and immune system. BPA was administrated to mice by p.o. (as a drinking water) dose on 0.015, 1.5 and 30 mg/ml for 4 weeks. The BPA treatment did not result in any change in body weight, spleen weight and distribution of lymphocyte subpopulation collected from spleen. BPA induced prolactin production in spleen, and exposure of SPA increased the activity of splenocyte proliferation in response to Con A (p<0.001). The production of a strong Th-1 type cytokine ($IFN-{\gamma}$) was induced while Th-2 type (IL-4) was suppressed by SPA treatment. These were consistent with RT-PCR results of transcription factor GATA-3 and IRF-1. These findings suggested that stimulation of prolactin production by estrogenic effects of SPA would affect cytokine profiles, and lead to imbalanced cellular immune response. In addition, we could speculate that prolactin and cytokine is important mediator involved in network between neuroendocrine and immune system by BPA.

• Korean Journal of Medicinal Crop Science
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• v.14 no.3
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• pp.183-187
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• 2006

This study carried out to analize quality in the evaluation based on the grades such as raw ginseng and red ginseng between Korean (Panax ginseng C. A. Meyer) and American ginseng (Panax quinquefolium L). American ginseng was small in root length, root diameter and root weight and emergence many secondary root from rhizome and main root. Therefore body form was bad compared with Korean ginseng. As for yield of dry, Korean ginseng was 30.4 % and American ginseng was 33.8% but as for yield, Korean ginseng was 80.4% and American ginseng was 72.2%. There were as many Korean ginseng in raw ginseng first grade by about twice compared with American ginseng. However there were many American ginseng in second grade. On the other hand, Korean ginseng producted high Chunsam compared with American ginseng. The cause of decreasing quality was inside cavity and inside white in Korean and American ginseng. Especially, the inside white occurrence about 3 times compared with inside cavity in American ginseng. In the case of distribution of weight size, Korean ginseng was much above 20Ji but American ginseng was much under 20Ji.

• The Journal of Internal Korean Medicine
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• v.22 no.4
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• pp.513-517
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• 2001

Objective : Recently many studies of herbal medication to promote growth have been implemented. The purpose of this study was to identify the feasibility and safety of herbal medication on short stature. Methods : 143 patients(87 males, 56 Females)who visited with short stature at Kangnam CHA Oriental Hospital From February 1999 to January 2000 and were treated during 6 months, were available for this study. We treated with 5 herbal medications.(Soeumin hyangbujapalmultang-gagambang, Soyangin yukmijihwangtang-gagambang, Taeumin chungsimyunjatang-gagambang, Boa-tang, Boikyangwi tang) At the begining of the treatment and after 6 months treatment, We measured height, weight and body mass index(BMI). And we investigated changes of aspartate aminotransferase(AST), alanine aminotransferase(ALT), blood urea nitrogen(BUN), alkaline phosphatase(ALP), creatinine. Results: The distribution of ages was from 5 years old to 17 years old. After herbal treatment, mean height, mean weight, mean BMI and mean percentile grade increased $138.5{\pm}15.6$ to $141.9{\pm}15.1$, from $36.9{\pm}13.2$ to $38.9{\pm}13.2$, from $18.5{\pm}3.29$ to $18.7{\pm}3.21$, from $3.2{\pm}1.2$ to $3.4{\pm}1.2$. The contents of AST, ALT, BUN, ALP and Creatinine were not showed any significant change. Conclusions : In the results We recognized Short stature was showed prominent feasibility and safety of herbal medication. Herbal Medication in patients with short stature will improve height velocity without liver and kidney function disorders.

• Journal of the Korean Society of Physical Medicine
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• v.7 no.2
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• pp.223-230
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• 2012

Purpose : The purpose of this study was to analyze weight bearing of cane and affected foot at different speeds during walking. Methods : Thirteen subjects (6 males, 7 females) with stroke enrolled in the study. A foot sensor and an instrumented cane were integrated to analyze the vertical peak force on the affected foot and the cane. Results : The applied vertical peak force on the cane were $12.02{\pm}4.80%$ (slow speed), $7.97{\pm}3.95%$ (comfortable speed), and $6.86{\pm}3.30%$ (fast speed) body weight, respectively. The results indicated significantly lower vertical peak force on the affected foot in the low speed walking condition when compared to the fast walking (p<.05) and the comfortable walking (p<.05) conditions. The correlations between TUG and vertical peak force on the cane and affected foot were .71, and -.70 (p<.01). There was a higher correlation between the vertical peak force on the cane and affected foot were -.87(p<.01). Conclusion : In conclusion, slower walking speed applied greater vertical peak force on the cane. On the contray, slower walking speed applied less vertical peak force on the affected foot. Further studies, duration of force should be measured at different speeds during walking in lower and higher functioning hemiparetic subjects, as its use may mask underlying gait impairment.

• Journal of Aquaculture
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• v.11 no.3
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• pp.401-419
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• 1998

The structure of benthic algal flora and feeding behavior of sea urchins (Anthocidaris crassispina and Hemicentrotus pulcherrimus), were investigated from the eight different locations along the coast of Cheju Island, Korea. Biomass distribution and dominance of the algal communities were studied in relation to the gut contents and population parameters of the sea urchins. As a result, although the largest algal biomass and biological characteristics of sea urchins, such as test diameter, test hight, body weight, gonad weight, etc. This inhdicated that sea urchins would not be dependednt sorely on the abundance of algal foods, and they might feed on other food items. In order to know such a trend with regard to food selectivity, the diets consumed by sea urchins were analyzed, and it was found that they were composed of benthic and drifted algae, various animal components (sponges, bryozoans, crustaceans, and various unidentified capsulated eggs, etc.) and biets turned out to be smaller than might be expected, and it is postulated that sea urchins were not likely to be the major grazing animals for the formation of algal bed and also canopy deterioration, so-called "white incrustation."

• Journal of the Korean Society of Clothing and Textiles
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• v.39 no.1
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• pp.55-62
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• 2015

This study investigated the thermal insulation of an air-cell pack embedded jacket and down jackets to understand the potential of air-cell pack as a filler for winter outdoor wear. A thermal manikin measured the thermal insulation of the following jackets: HD (heavy down jacket, total weight (Tw) 750g, goose down weight (Dw) 350g), LD (light down jacket, Tw 560g, Dw 140g), AF (air-cell pack embedded jacket, Tw 490g, trunk goose down in LD was replaced to air cell), F (film jacket, Tw 469g, but removed the air in the air-cell pack from the AF), and Control (control jacket, Tw 438g, removed the air-cell pack film from the F). Thermal insulations of each experimental condition were measured in a static standing posture. Total thermal insulations (IT) were 1.29clo (HD), 1.23clo (LD), 1.16clo (AF), 1.20clo (F), and 1.08clo (Control). Body regional thermal insulation was higher in the chest and back than in the abdomen and hip in all conditions. The results suggest that an economical and versatile outdoor jacket with superior thermal insulation will be feasible if the air volume is properly controlled in air-cell pack embedded jackets in consideration of regional different distribution and used in combination with film and down.

• The Journal of Korean Obstetrics and Gynecology
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• v.33 no.4
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• pp.56-74
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• 2020

Objectives: The purpose of this study is to analyze the current characteristics of outpatients using herbal medicine for treating Sanhupung and provide treatment instructions in the clinical field. Methods: To analyze characteristics of outpatients with postpartum disease, I searched medical records from July 1, 2017 to June 30, 2020 using O94 (Sequelae of complication of pregnancy) in an oriental medicine hospital and 73 Sanpuhung patients were analyzed. Results: 1. The average age of Sanpuhung outpatients was 32.83±3.14 years old. The mean body weight difference between full-term pregnancy and visiting date was -7.79±4.23 kg. 2. The most chief complaints of Sanpuhung outpatients were musculo-skeletal symptoms in 57 (78.08%) patients followed by neuropsychiatric symptoms and circulatory symptoms. In musculo-skeletal symptoms, the most chief complaint area was wrist in 48 (65.75%) patients followed by waist, shoulder and knee. 3. 68 (93.15%) patients gave birth between 38 and 42 weeks of pregnancy, 33 (45.20%) patients gave birth by caesarean operation. Patients delivered in July visited the hospital most frequently for postpartum care. 4. 68 (93.15%) patients gave birth to single-born babies. The average birth weight was 3.13±0.45 kg. 5. In distribution from delivery to visitation period, the average was 65.08±103.2 days. The number of visits less than two times was 72 (98.63%). 6. A total of 73 outpatients got herbal medicine. Depending on the symptoms, herbal medicines were different from each other. Ikgibohyeol-tang-gagambang, Ojeok-san-gagambang and Gunggui-tang-gagambang were mostly used. Conclusions: These results could be helpful to treat Sanhupung patients in Korean gynecologic clinical fields.

• Journal of the Korea Convergence Society
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• v.9 no.2
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• pp.303-311
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• 2018

Squat exercise is one of the free weight exercises that are recognized as important from a bio-mechanical point of view. It is an important exercise to train lower extremity muscles in daily activities or sports activities and to strengthen trunk and lower body strength. It is effective and accurate to use a variety of assistive devices to calibrate athletic posture with squat exercise supported interactive device. The issues of the structural analysis for design a foot plate for squat exercise is to model the behavior by simplifying the dynamic behavior. In this paper, the authors proposed a exercise system design method for the vertical load distribution and bio-mechanical signal process used for the squat exercise mechanism analysis, and based on these results, designed device can make the more safe and reliable free weight exercise. It is applied to system design through design method with kinematic dynamic, VR device and estimation model of exercise.