• Clinical and Experimental Pediatrics
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• 제63권8호
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• pp.301-309
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• 2020

Human breast milk (HBM) is essential for the infant's growth and development right after birth and is an irreplaceable source of nutrition for early human survival. Various infant formulas have many similarities to HBM in many components, but there is no perfect substitute for HBM. Recently, various breast milk components and their roles have been studied according to the development of various analysis techniques. As is already well known, HBM contains about 87%-88% water, and 124-g/L solid components as macronutrients, including about 7% (60-70 g/L) carbohydrates, 1% (8-10 g/L) protein, and 3.8% (35-40 g/L) fat. The composition may vary depending on the environmental factors, including maternal diet. Colostrum is low in fat but high in protein and relatively rich in immuneprotective components. Although HBM contains enough vitamins to ensure normal growth of the infant, vitamins D and K may be insufficient, and the infant may require their supplementation. Growth factors in HBM also serve as various bioactive proteins and peptides on the intestinal tract, vasculature, nervous system, and endocrine system. In the past, HBM of a healthy mother was thought to be sterile. However, several subsequent studies have confirmed the presence of rich and diverse microbial communities in HBM. Some studies suggested that the genera Staphylococcus and Streptococcus may be universally predominant in HBM, but the origin of microbiota still remains controversial. Lastly, milk is the one of most abundant body fluid of microRNAs, which are known to play a role in various functions, such as immunoprotection and developmental programming, through delivering from HBM and absorption by intestinal epithelial cells. In conclusion, HBM is the most important source of nutrition for infants and includes microbiomes and miRNAs for growth, development, and immunity.

• 한국정보통신학회논문지
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• 제15권10호
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• pp.2079-2086
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• 2011

최근 헬스케어 응용 시스템 중의 하나인 자가 진단 시스템 기술의 연구가 활발하게 이루어져 왔다. 이와 함께 본 연구논문은 PC, RFID, 생체신호측정기와 연동된 자가 혈당측정 시스템 및 사용자가 이해하기 쉬운 인터페이스를 구현하는데 있다. 따라서 PC, RFID, 그리고 생체신호측정 센서와 연동되어 손쉽게 자가진단 데이터를 확보할 수 있도록 디바이스와 PC사이의 통신을 위한 손쉬운 인터페이스 구성과 RFID 태그 및 리더기 통신 상태를 분석, 테스트를 수행했다. 즉, 자가 혈당측정 데이터에 대한 통신 프로토콜 수행(프로토콜 정의에 따른 리퀘스트 및 리스폰스 데이터 분석)으로 연월일, 체온 및 혈당수치, 그리고 혈당체크 시점 등 신뢰성 높은 결과가 출력되었음을 나타내었다.

• 대한한방부인과학회지
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• 제31권3호
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• pp.33-49
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• 2018

Objectives: The purpose of this study was to investigate the correlation between Pattern identification instrument and biomarkers in polycystic ovary syndrome patients. Methods: Pattern identification instrument questionnaire, Sasang constitutional test, body composition test, pulse analyzing test, laboratory test were performed and the results were analyzed. Correlation analysis was performed between pattern identification and laboratory test results. Results: Testosterone, SHBG, $17{\alpha}$-OH-progesterone, AMH were highest in the Kidney-Yang Deficiency (腎陽虛) group. LH, FSH, LH/FSH ratio were the highest in the Endogenous Heat due to Yin Deficiency (陰虛內熱) group. DHEA-S was the highest in the Dampness-Heat in Liver Meridian (肝經濕熱) group. E2, Prolactin, Cholesterol, Triglyceride, HDL-Cholesterol, LDL-Cholesterol, Glucose (FBS), Insulin, HOMA-IR ratio, HbA1c were the highest in the Phlegm-Dampness (痰濕) group. Conclusions: In this study, we obtained basic data analyzing the correlation between pattern identification instrument and biomarkers in polycystic ovary syndrome patients. If further studies are performed, we expect to be able to obtain clues to study the mechanism of polycystic ovary syndrome.

• 한국측량학회지
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• 제2권1호
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• pp.54-64
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• 1984

본 연구는 지상사진기에 의한 구조물(석탑)측정에 관한 것으로서 석탑중 통일신라의 석탑인 감은사지 삼층석탑, 고선사지 삼층석탑, 불국사 삼층석탑(석가탑) 및 불상인 석굴암 본존상, 광주철조여내좌상을 대상으로 조형비를 분석하여, 조형원리에 접근하는데 의의를 갖고 있다. 등고선도와 실측치를 정밀하게 얻을 수 있었으며, 이를 바탕으로 조형비를 분석한 결과, 3재의 석탑과 2개의 불상에서 공통점을 발견할 수 있었다. 우선 석탑의 경우 옥개석폭들은 8 : 7 : 6의 비예관계로 구성되어 있었으며, 상대갑석을 밑변으로 정삼각형과 이등변 삼각형을 긋고, 그 정점사이의 거리를 반경으로 하여 정삼각형의 정점에서 원을 그리면 삼층 옥신 윗면과 일치하였고, 또 기준면으로부터 $70^{\circ}$의 2등변 삼각형을 그러는 경우 상대갑석의 끝점들을 거의 통과하며, 삼층 옥개석의 낙수면과 일치함을 알 수 있었다. 불상의 경우 양 눈사이의 중점을 중심으로 원이 성립되고, 어깨와 명치를 연장하면 무릎에 접함을 알 수 있었다.

• 패션비즈니스
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• 제22권1호
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• pp.1-19
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• 2018

The purpose of this study is to analyze the fashion style of Kate Middleton, the Royal Family, and to examine the social and cultural influence of Middleton fashion. We selected 314 photographs collected from a Google site and Gettyimages.com April 2011-December 2016 as the final research subjects. We categorized the situation by domestic events, royal events, diplomatic activities, and social contribution activities, and analyzed fashion styles focusing on item composition, color, material, silhouette, detail, trimming, and length. As a result of the study, the one piece was the highest in the combination of items, and the color was the most in white. The color tones were mostly vivid, and the material texture was silky. The image was classic, and the dress code was high in semi-formal. In a situational style, the coat was the most common at the Royal Family events and blue or white of the light tones appeared in the formal style of the classic image. In domestic events, there were many silky textures of modern image, and vivid, strong tonal knee length H line dress was the most prevalent. During diplomatic activities, various colors such as red, green, gray appeared in addition to blue or white and in social contribution activities, many dresses of vivid and dark tones of red appeared in the dress code as semi-formal. In conclusion, the stylistic features of Kate Middleton and the Royal Family are largely in the form of royal and noble, low cost and chic, and body-conscious styling.

• Environmental Analysis Health and Toxicology
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• 제25권3호
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• pp.215-222
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• 2010

The market size of engineered nanoparticles is rapidly increasing due to the fast application of nanotechnologies into different industries and consumer products. The development of new technology and materials has improved human's quality of life, but it also entails the possibility of exposure to new materials. In this study, we compared the distribution in the body by the inflow of silver nanoparticles having another diameter and shape at 1 h or 24 h after injection via the tail vein. And, we compared the cell composition and cytokine concentration in BAL fluid, and histopathological changes. As results, discharge of silver nanoparticles having small diameter and sphere shape was more rapid than that of big diameter or plate shape. It is estimated that the toxicity in liver and lung was proportional to accumulation level. The persistence of inflammation was also longer in mice treated with plate shape. Consequently, we suggest that the first choice of silver nanoparticles having small diameter and sphere shape in applying is desirable.

• Journal of Korean Medical Science
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• 제33권50호
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• pp.320.1-320.8
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• 2018

Background: Muscle mass and muscle function are related to depressed mood in studies of adults. Like adults, Korean students are highly likely to suffer from decreased muscle mass due to social conditions. In this study, we evaluated the muscle mass status of Korean adolescents and assess the effect of muscle on depressive mood. Methods: A total of 1,233 adolescent boys and girls participants from the Korea National Health and Nutrition Examination Survey were enrolled in our study. Participants underwent dual-energy X-ray absorptiometry for assessment of appendicular muscle mass and completed questionnaires regarding depressed mood, stress, suicidal ideations, and attempts. Results: There was no difference in depressive mood according to muscle mass among boys (P = 0.634); girls with decreased muscle mass had a greater tendency for depressed mood compared to girls with optimal muscle mass (P = 0.023). After adjusting for age, waist circumference-to-height ratio, smoking status, alcohol consumption, frequency of physical activity, self-reported obesity, weight-loss efforts, and monthly household income, girls with low muscle mass (LMM) were 2.60 times more at risk of developing depression than girls with normal muscle mass (95% confidence interval [CI], 1.05-6.49; P = 0.040). This trend was similar for girls with LMM with obesity (95% CI, 1.00-11.97; P = 0.049). Conclusion: Adolescent girls who have insufficient muscle mass are more likely to report depressed mood than girls who have ideal muscle mass. Interventions for maintaining proper muscle mass are required.

• Animal Bioscience
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• 제34권10호
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• pp.1684-1694
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• 2021

Objective: This study investigated the association between feed efficiency, physicochemical properties, flavor precursors and biomolecules in the thigh meat of Korat (KR) chickens. Methods: The feed intake and body weight of individual male KR chickens were recorded from 1 to 10 weeks old to calculate the individual residual feed intake (RFI) of 75 birds. At 10 weeks of age, chickens with the 10 highest (HRFI) and lowest RFI (LRFI) were slaughtered to provide thigh meat samples. The physicochemical properties (ultimate pH, water holding capacity [WHC], drip loss) and flavor precursors (guanosine monophosphate, inosine monophosphate (IMP), adenosine monophosphate and inosine) were analyzed conventionally, and Fourier transform infrared spectroscopy was used to identify the composition of biomolecules (lipids, ester lipids, amide I, amide II, amide III, and carbohydrates) and the secondary structure of the proteins. A group t-test was used to determine significant differences between mean values and principal component analysis to classify thigh meat samples into LRFI and HRFI KR chickens. Results: The physicochemical properties of thigh meat samples from LRFI and HRFI KR chickens were not significantly different but the IMP content, ratios of lipid, lipid ester, protein (amide I, amide II) were significantly different (p<0.05). The correlation loading results showed that the LRFI group was correlated with high ratios of lipids, lipid esters, collagen content (amide III) and beta sheet protein (rg loading >0.5) while the HRFI group was positively correlated with protein (amide I, amide II), alpha helix protein, IMP content, carbohydrate, ultimate pH and WHC (rg loading >0.5). Conclusion: The thigh meat from chickens with different RFI differed in physiochemical properties affecting meat texture, and in the contents of flavor precursors and biomolecules affecting the nutritional value of meat. This information can help animal breeders to make genetic improvements by taking more account of traits related to RFI.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제24권4호
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• pp.47-57
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• 2018

Purpose and Methods: Currently, Korea has the lowest fertility rate among OECD countries. It is also true that from the aspect of encouraging childbirth policy, as the use of automobiles has increased, the interest in securing parking spaces has also become more important. However, there are efforts and researches on the supplying parking spaces for the general public in society not to the positive discrimination such as elders or pregnant women. On the other hand, there is a growing need for a dedicated parking space for pregnant women due to the changing social environment and increasing number of female drivers. At this point, proper design of the maternity parking spaces is essential. Therefore, this study is analyzing the characteristics of pregnant women such as measurements and certain actions and case studies of domestic and oversea. Through the analysis of these factors, the following results were derived. Results: First, it was determined that the important factor in the planning of the parking-block for pregnant women was the human body size of pregnant women. And the required dimensions of movement of pregnant women were derived. Second, the dimensions of automobile were analyzed and applied from the most used vehicles in the family composition. Third, after the observations, the status of the parking spaces of the pregnant women and observations showed that the drivers not only the pregnant women but others were using the spaces improperly. Fourth, at certain conditions of the parking spaces, in order to improve the efficiency of the parking spaces, it is necessarily considered that the usage of designated accessible parking spaces can be used together by not only the disabled but also to the passengers who are classified as 'transportation weak' such as pregnant women. Implications: In this study, the researcher will propose the shape and size of the parking-block for pregnant women considering the elements derived above.

• 동의생리병리학회지
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• 제33권4호
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• pp.239-248
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• 2019

There are no published data on Gyeongokgo (GOK) safety or efficacy despite being commonly use. The Gyeongokgo (GOK) is commonly used in traditional Korean medicine to promote a health qi and blood, but their objective data was not sufficient in clinical field. To investigate the safety and efficacy of GOK with hematologic and serologic testing and the change of the quality of life in healthy individuals. Randomized, subject-assessor-blind, placebo-controlled, single-center pilot study Participants and Interventions 29 healthy volunteer subjects were randomly placed into the GOK group (n = 20) or placebo control group (n = 9) and instructed to take one treatment packet (GOK or placebo) twice daily for 4 weeks. Subjects were assessed using the Fatigue Severity Scale (FSS) and Short Form 36 Health Survey (SF-36) and underwent hematologic and serologic tests and body composition analysis. The FSS total score (p = 0.093) and SF-36 general health index (p = 0.002) were improved following treatment in the GOK group. Post-treatment thyroid-stimulating hormone levels were increased in the GOK group compared with pre-treatment levels (p = 0.0042). C-reactive protein levels decreased (p = 0.0256) in the GOK group compared with that the placebo group. In time-series tests, GOK did not affect post-prandial serum triglycerides, glucose, insulin, or C-peptide levels. Notably, elevations in serum fasting triglycerides at 2- (p = 0.0333) and 4-hours (p = 0.0414) post-prandial were lower than those in the placebo group. GOK reduced fatigue levels and did not significantly affect laboratory test results performed to measure safety, serum glucose, and lipid profiles. Post-meal triglyceride levels were effectively reduced with treatment.