• 제목/요약/키워드: BoLA

검색결과 136건 처리시간 0.026초

소에서의 유전적 다형의 이용 (Utilization of Genetic Polymorphisms in Cattle)

  • 신형두
    • 한국수정란이식학회지
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    • 제10권1호
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    • pp.23-31
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    • 1995
  • Several kinds of analytic methods for genetic polymorphism in cattle, including bovine blood typing, PCR-RFLP, BoLA and microsatellite typing were described. A few respect to consider for choosing method for actual application of genetic polymorphism were emphasized. The probability of relationship between characteristics and gene concerned, repetibility and easiness of methods applied and the possibility of clarification for segregation pattern should be deliberated.

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Opposing Effects of ERK and p38 MAP Kinases on HeLa Cell Apoptosis Induced by Dipyrithione

  • Fan, Yumei;Chen, Hui;Qiao, Bo;Luo, Lan;Ma, Hsiaoyen;Li, Heng;Jiang, Jihong;Niu, Dezhong;Yin, Zhimin
    • Molecules and Cells
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    • 제23권1호
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    • pp.30-38
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    • 2007
  • Dipyrithione (2, 2'-dithiobispyridine-1, 1'-dioxide, PTS2), a pyrithione derivate, is highly bactericidal and fungicidal. In this study we examined its apoptotic effect on HeLa cells. PTS2 induced HeLa cell death in a dose and time dependent manner. ERK1/2 and p38 were markedly activated, but little JNK1/2 activation was detected. Suppression of p38 activation by SB203580 reduced the extent of apoptosis of the HeLa cells and also prevented induction of p21, release of cytochrome c, and cleavage of caspase-3 and PARP. Inhibition of ERK1/2 with PD98059 increased apoptosis, indicating that ERK1/2 activation has an anti-apoptotic effect on PTS2-induced HeLa cell apoptosis. PTS2 also inhibited murine sarcoma 180 and hepatoma 22 tumor growth in an animal tumor model. Our findings indicate that PTS2 possesses anti-tumor activity, that caspase-3 and poly (ADP-ribose) polymerase (PARP) are involved in PTS2-induced HeLa cell apoptosis and that ERK1/2 and p38 have opposing effects on this apoptosis.

La이 도핑된 CuO-ZnO-Al2O3 복합 산화물의 합성공정개발 (Development and Synthesis of La Doped CuO-ZnO-Al2O3 Mixed Oxide)

  • 정미원;임샛별;문보람;홍태환
    • 한국재료학회지
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    • 제21권1호
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    • pp.67-71
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    • 2011
  • La doped CuO-ZnO-$Al_2O_3$ powders are prepared by sol-gel method with aluminum isopropoxide and primary distilled water as precursor and solvent. In this synthesized process, the obtained metal oxides caused the precursor such as copper (II) nitrate hydrate and zinc (II) nitrate hexahydrate were added. To improve the surface areas of La doped CuO-ZnO-$Al_2O_3$ powder, sorbitan (z)-mono-9-octadecenoate (Span 80) was added. The synthesized powder was calcined at various temperatures. The dopant was found to affect the surface area and particle size of the mixed oxide, in conjunction with the calcined temperature. The structural analysis and textual properties of the synthesized powder were measured with an X-ray Diffractometer (XRD), a Field-Emission Scanning Electron Microscope (FE-SEM), Bruner-Emmett-Teller surface analysis (BET), Thermogravimetry-Differential Thermal analysis (TG/DTA), $^{27}Al$ solid state Nuclear Magnetic Resonance (NMR) and transform infrared microspectroscopy (FT-IR). An increase of surface area with Span 80 was observed on La doped CuO-ZnO-$Al_2O_3$ powders from $25m^2$/g to $41m^2$/g.

3D Architectures of LaVO4:Eu3+ Microcrystals via an EG-assisted Hydrothermal Method: Phase Selective Synthesis, Growth Mechanism and Luminescent Properties

  • Ding, Yi;Zhang, Bo;Ren, Qifang;Zhang, Qicai;Zha, Weiwei;Li, Xin;Chen, Shaohua;Oh, Won-Chun
    • 한국세라믹학회지
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    • 제54권2호
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    • pp.96-101
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    • 2017
  • In this article, pure $m-LaVO_4:Eu^{3+}$ and $t-LaVO_4:Eu^{3+}$ nanocrystals were prepared by an EG-assisted hydrothermal method with regular shapes. A series of controlled experiments showed that the pH value of a mixed solution, the volume ratio of $EG/H_2O$ and the dosage of the doped $Eu^{3+}$ all had an important effect on the sizes and shapes of the final products. Furthermore, the constitutional unit of the products changed from 0D to 2D with an increase in the EG dosage. The PL results showed that $t-LaVO_4$ doped with $Eu^{3+}$ ions had better luminescence properties than $m-LaVO_4$ due to its special structure. All of these results not only expand our understanding of the luminescence properties of lanthanide orthovanadates, but they also elucidate the principles of the crystal growth.

Li[Ni0.3Co0.4Mn0.3]O2 양극물질의 Li-La-Ti-O코팅 효과 (The Effects of Li-La-Ti-O Coating on the Properties of Li[Ni0.3Co0.4Mn0.3]O2 Cathode Material)

  • 이혜진;윤수현;박보건;유제혁;김관수;김석범;박용준
    • 한국전기전자재료학회논문지
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    • 제22권10호
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    • pp.890-896
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    • 2009
  • Li(Ni, Co, Mn)$O_2$ has been known as one of the most promising cathode materials for lithium secondary batteries. However, it has some problems to overcome for commercialization such as inferior rate capability and unstable thermal stability. In order to address these problems, surface modification of cathode materials by coating has been investigated. In the coating techniques, selection of coating material is a key factor of obtaining enhanced properties of cathode materials. In this work, we introduced solid electrolyte (Li-La-Ti-O) as a coating material on the surface of $Li[Ni_{0.3}Co_{0.4}Mn_{0.3}]O_2$ cathode. Specially, we focused on a rate performance of Li-La-Ti-O coated $Li[Ni_{0.3}Co_{0.4}Mn_{0.3}]O_2$ cathode. Both bare and Li-La-Ti-O 2 wt.% coated sample showed similar discharge capacity at 0.5C rate. However, as the increase of charge-discharge rate to 3C, the coated samples displayed better discharge capacity and cyclic performance than those of bare sample.