• 대한전기학회:학술대회논문집
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• 대한전기학회 2002년도 합동 추계학술대회 논문집 정보 및 제어부문
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• pp.11-14
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• 2002

Incurable disease such as palsy and imbecility results from bolld pressure and bloodstream hitch. These diseases result in high blood pressure and brain bloodstream obstacle. So, we developed bloodstream improvement system that can improve bloodstream state using physical stimulation. It controls inflow and outflow of air to press and oppress human body sequentially. We can select stimulation region, pattern, pressure and time. Also, it can improve brain bloodstream state, because it can treat stress or headache putting pressure band on head. It can be used as breathing assistance system which has function for breath synchronization.

• Advances in pediatric surgery
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• 제16권1호
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• pp.25-31
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• 2010

Hickman catheters are tunneled central venous catheters used for long-term venous access in children with malignancies. The appropriate management for various kinds of catheter related complications has become a major issue. We retrospectively analyzed the clinical, demographic, and surgical characteristics in 154 pediatric hemato-oncology patients who underwent Hickman catheter insertion between January 2005 and December 2009. There were 92 boys and 62 girls. The mean age at surgery was $7.6{\pm}5.1$ years old. The mean operation time was $67.4{\pm}21.3$ minutes and C-arm fluoroscopy was used in 47(30.5 %). The causes of Hickman catheter removal were termination of use in 82 (57.3 %), catheter related bloodstream infection in 44(30.8 %), mechanical malfunction in 11(7.7 %), and accidents in 6(4.2 %). Univariate and multivariate analysis for associated factors with catheter related bloodstream infection showed that there were no statistically significant associated factors with catheter related infection complications. All cases except two showed clinical improvement with catheter removal and relevant antibiotics treatment. The mean catheter maintenance period in patients of catheter removal without complications was $214.9{\pm}140.2$ days. And, The mean catheter maintenance period in patients of late catheter related bloodstream infection was $198.0{\pm}116.0$ days. These data suggest that it is important to remove Hickman catheter as soon as possible after the termination of use. When symptoms and signs of complications were noticed, prompt diagnostic approach and management can lead to clinical improvements.

• Neonatal Medicine
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• 제28권3호
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• pp.116-123
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• 2021

Purpose: The aim of this study was to estimate the effect of targeting risk factors for the control of central line-associated bloodstream infection (CLABSI) among high-risk infants in a tertiary neonatal intensive care unit (NICU). Methods: Infants admitted to the NICU and diagnosed with CLABSI from January to December 2013 were eligible for inclusion to the study. The CLABSI group (n=47) was matched in a 1:2 ratio to the control group (n=94) based on gestational age, birth weight, and Score for Neonatal Acute Physiology-II. Risk factors for CLABSI were identified using the Cox proportional hazard model, and analysis of the effect of these risk factors targeting infection control was performed. Results: The risk factors associated with CLABSI were prolonged central line dwell days (adjusted hazard ratio [HR], 1.028; 95% confidence interval [CI], 1.011 to 1.045; P=0.001), use of a silicone catheter (adjusted HR, 5.895; 95% CI, 1.893 to 18.355; P=0.002), surgical treatment (adjusted HR, 3.793; 95% CI, 1.467 to 9.805; P=0.006), and less probiotic supplementation (adjusted HR, 0.254; 95% CI, 0.068 to 0.949; P=0.042). By targeting these risk factors with a quality improvement initiative, the mean CLABSI incidence rate per 1,000 catheter-days decreased from 6.6 to 3.1 (P=0.004). Conclusion: Targeting risk factors for infection control significantly reduced the rate of CLABSI among high-risk infants in the NICU.

• 디지털융복합연구
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• 제14권10호
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• pp.563-570
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• 2016

본 연구는 동양의학의 관점에서 혈액의 흐름에 도움이 되는 5종의 한약재를 이용하여 영양성분과 항산화 활성을 분석하고자 한다. 일반 영양성분 중 혈액의 구성성분과 관계되는 단백질, 철분 및 구리의 함량은 하수오 (20.28%, $132.22{\mu}g$/100 g, $26.54{\mu}g$/100 g), 당귀 (16.54%, $98.20{\mu}g$/100 g, 그리고 $32.15{\mu}g$/100 g)및 백작약(18.67%, $62.10{\mu}g$/100 g, 그리고 $20.32{\mu}g$/100 g) 의 함량이 다른 재료에 비해 유의적으로 높은 수준이었고, 총 폴리페놀과 총 플라보노이드 함량은 당귀(157.24 mg GAE/g, 108.97 mg QUAC/g), 하수오(124.17 mg GAE/g, 112.02 mg QUAC/g), 백작약(125.25 mg GAE/g, 65.66mg QUAC/g) 순으로 그 함량이 높았으며, DPPH 라디컬 소거능으로 분석한 항산화 활성은 하수오(0.35 $IC_{50}$ mg/ ml), 당귀(0.68 $IC_{50}$ mg/ ml) 및 백작약(0.72 $IC_{50}$ mg/ ml) 순으로 그 활성이 큰 것으로 나타났다 본 연구는 한약재를 활용하여 동 서 융합적 효능 접근을 시도하고 혈류개선을 위한 천연물 유래 성분의 개발에 기초 자료로 활용 하고자 한다. 또한 이러한 한약재의 혈류개선을 위한 기능성 소재로의 개발 및 활용가치를 알아보고자 한다.

• 디지털융복합연구
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• 제11권3호
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• pp.337-344
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• 2013

본 연구의 목적은 유산소성 운동프로그램 참여가 시각장애인의 호흡순환기능 및 동맥파속도에 어떠한 영향을 미치는가를 규명하기 위한 목적으로 수행되었다. 본 연구의 목적을 인지하고 참여의사를 밝힌 1급 시각장애인 20명이었으며, 보호자를 통하여 피험자 참여의 동의서를 받았다. 이들은 유산소성운동집단 10명과 통제집단 10명으로 무선배정으로 분류하였다. 유산소성운동집단은 12주동안 50-70%HRmax 강도로 주 5회 1일 준비운동, 본운동, 정리운동 총 60분으로 실시하였다. 본 연구의 자료처리는 독립변인으로 한 반복측정에 의한 이원변량분석(two-way repeated ANOVA)을 실시하였으며, 상호작용 효과를 검증하기 위해 paired t-test를 실시하였으며, 통계적 유의수준은 p<.05로 설정하여 다음과 같은 결론을 얻었다. 첫째, 실험집단에서 체중과 체지방률은 사전과 비교하여 사후 유의한 감소를 나타냈다(p<.05). 둘째, 실험집단에서 최대산소섭취량, 최대심박수, 최대환기량은 사전과 비교하여 사후 유의한 증가를 나타냈다(p<.05). 셋째, 실험집단에서 동맥파속도는 사전과 비교하여 유의한 증가를 나타냈다(p<.05), 넷째, 실험집단에서 수축기혈압은 사전과 비교하여 사후 유의한 감소를 나타내지 않았다(p>.05). 이상의 결과를 종합해 볼 때 유산소성 운동프로그램 참여는 호흡순환기능 및 혈류순환과 혈관기능 개선에 효과적으로 나타났다.