• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.22 no.2
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• pp.176-185
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• 2009

Objective: The aim of this study was to investigate the correlation between atopic dermatitis and a comprehensive diagnosis of Qi Blood Water in children with or without atopic dermatitis. Methods: We surveyed 206 children in Seoul Jungnang-gu nursery by reviewing the questionnaires following a medical examination. Comprehensive diagnosis of Qi Blood Water was investigated by questionnaires and composition scores and total scores were calculated from the symptom scores. Atopic dermatitis was diagnosed by ophthalmo.otolaryngo.dermatologist and atopic dermatitis symptom was measured by a Visual analogue scale(VAS). Comparisons between the atopic and non-atopic groups were made based on the atopic dermatitis symptom scale, composition scores and total scores. Results : 1. Of the 206 patients, 153(74.27%) were included in the non-atopic group, while 53(25.73%) were included in the atopic group. There was no difference in average age between the two groups. 2. The atopic dermatitis symptom scale of atopic group(3.21$\pm$2.018) was significantly higher than that of non-atopic group(0.04$\pm$0.28). 3. Qi deficiency, Qi stagnation, Blood stasis and Water congestion scores and the total scores of the atopic group were higher than those of the non-atopic group, but it was not significant. 4. The Qi regurgitation and Blood deficiency scores of atopic group were significantly higher than those of the non-atopic group. 5. There was a highly significant correlation between the atopic dermatitis symptom scale and Qi regurgitation scores, and between the atopic dermatitis symptom scale and Blood deficiency scores. Conclusion : Atopic dermatitis seems to have a special feature reflecting the state of comprehensive diagnosis of Qi regurgitation and Blood deficiency in children.

• The Journal of Internal Korean Medicine
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• v.18 no.1
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• pp.207-217
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• 1997

The oriental medicine based on the traditional Chinese medicine has developed characteristically according to the history and racial character respectively; China, Korea and Japan. Japan, among these nations, has accepted western medicine earlier than other nations and has tried to compare western and oriental medicine and combine them. In Japanese traditional medicine, it is characteristic that the old medical classics focusing on Sanghannon (傷寒論) and Geumgyeyoryak(金?要略) has developed The recent tendencies of clinical medicine and researches in Korean oriental medicine are mostly about the study of oriental medicine in view of western medicine and the combination of western and oriental medical treatment like Japan. But the study on the Japanese oriental medicine hasn't so far been tried before in Korea. From now on, we should not overlook that a more interest on Japanese oriental medicine will be very useful. Therefore we have surveyed the background of its origin and the process of development of the theory of ${\ulcorner}$Qi, Blood and Body Fluids${\lrcorner}$. What we wish to show in this paper is to provide a source for the basic understanding by explaining a fundamental theory of physiology and pathology of Japanese oriental medicine. Concepts of ${\ulcorner}$Qi, Blood and Body Fluids${\lrcorner}$ suggested by Nangai Yoshimashi in 1792 is the way of thinking that the circulation of 3 factors- ${\ulcorner}$Qi, Blood and Body Fluids${\lrcorner}$ nourish human body. Among these 3 factors, if Qi does not function smoothly, it causes the condition of a disease like Qi-deficiency, imbalance of Qi-distribution or Qi-depression and stasis; in Blood's case, deficiency of Blood and Blood stasis; and as for Body Fluids, stasis of Body Fluids. In the recent trend of study, there's a try to combining the western and oriental medicine, Qi is considered as psychoneurotic system, Blood as circulatory and endocrinologic system and Body Fluids as immunologic system.

• Journal of Korean Medicine Rehabilitation
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• v.20 no.1
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• pp.13-26
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• 2010

Objectives : This study was designed to evaluate neuroprotective effects of Neutral Pharmacopuncture for Blood Stasis(NPBS) into SP10 and Tangguisusangami-tang (dangguixusanjiawei-tang)(TGT) in the experimental Traumatic Brain Injury(TBI)rats. Methods : Male rats were divided into 4 groups. Group I was no treatment after TBI. Group II was treatment with NPBS into SP10 after TBI. Group III was treatment with TGT after TBI. Group IV was NPBS into SP10 and TGT after TBI. The author carried out neurological motor behavioral, histological assessment test. Results : 1. In neurological motor behavior tests, motor and cognitive function recovery was significantly increased in the Group II, III, IV. Also Group IV was increased as compared with Group II, III. 2. In BAX expression, according to priority Group IV, III, II, I were decresed in 7 and 14 days later. Especially Group IV was significantly decreased in 14 days later. 3. In BCL-2 expression, Group IV was increased slightly in 7 days later. Most incresed expression was experimented in the Group IV in 14 days later. 4. In TUNEL expression, IV was decreased as compared with each Group I, II, III in 7 days later. Group IV, III were decreased as compared with each Group I, II, III in 14 days later. Conclusions : According to the results, NPBS and TGT can inhibit apoptosis of cells after TBI in rats by contol of BAX and BCL-2, TUNEL expression. And also can help neurological motor behavioral function.

• Journal of Acupuncture Research
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• v.37 no.3
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• pp.151-160
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• 2020

Background: Blood stasis (BS) is commonly used for pattern identification in traumatic injuries, including traffic accidents (TAs). Various studies have identified the efficacy of Korean medicine treatments for TA patients, but studies focusing on the BS-based herbal medicine (BSHM), including Tongdo-san (TDS), are rare. Methods: This was a single-center, prospective observational study, conducted from August 24^th, 2018 to December 27^th, 2018, which included 40 TA patients. Participants underwent routine Korean medicine treatments including acupuncture, electronic moxibustion, cupping, physical therapy, and herbal medicine. In the herbal medicine treatment, participants took BSHM with more than 3 days including taking TDS. The primary outcome measures were the scores from a 100 mm visual analogue scale (VAS) and numerical rating scale (NRS). Secondary outcome measures included scores from EuroQol-5 dimension (EQ-5D) and EQ-VAS questionnaires, the BS and cold/heat indices, and safety assessments. Results: There were significant improvements in the VAS, NRS, EQ-5D, EQ-VAS scores, and BS index after treatment. In the sub-analysis, VAS, NRS, EQ-5D, and EQ-VAS scores were higher in groups with a higher BS index. The moderate and severe BS index groups showed more improvement than the minor BS index group, and there was a significant difference in the EQ-5D scores. There was no significant differences observed in cold/heat index groups scores. Conclusion: BS is associated with TA-related symptoms. BSHM, including TDS, may significantly reduce BS, pain, and discomfort.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.2
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• pp.107-123
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• 2007

Purpose: Endometriosis has been thought to be related with blood stasis in uterus. Pinelliae Tuber is a herb which has effectiveness of dispelling phlegm which can be transformed into blood stasis, so is used in gynecology blood stasis-desease. Therefore in the present study, the effects of Pinelliae Tuber on endometriosis were investigated. Also retention enema therapy acts on the limited part directly, so is used frequently in gynecology clinic. This study was to examine the comparative effects on the surgical induction of endometriosis in the rat between orally and rectally administered with Pinelliae Tuber extract. Methods: The endometrial tissue was autografted to Rat's small intestine. Rats with surgically induced endometriosis were orally and rectally administerd with Pinelliae Tuber extract for 40 days. Size of ectopic uterine implants at the serosal wall and concentration of progesterone, estradiol, $TNF-{\alpha}$ and IL-2, IL-4, IL-6, IL-I0 in serum were examined and compared with the control group. Results: There was no difference in the size of ectopic uterine implants of experimental group compared with control group. The concentration of IL-10 level was significantly decreased in orally administered experimental group and the concentration of progesterone, IL-6 level was significantly decreased in rectally administered experimental group. There was no significant difference between orally and rectally administerd with Pinelliae Tuber. Conclusion: Judging from the above results, it can be suggested that Pinelliae Tuber should be not a useful agent for inhibiting the proliferation of uterine endometrial tissue. There is no difference between orally and rectally administerd with Pinelliae Tuber extract.

• Journal of Society of Preventive Korean Medicine
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• v.21 no.1
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• pp.41-48
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• 2017

Objectives : The aims of the current study were to assess the reliability and validity of the CoRe-Ditec-BS Questionnaire-II (BSQ-II; Blood stasis questionnaire-II) with 8 items including 5 items related women added to BSQ-I that was consisted of 36 items and developed in 2013. Methods : Between May 2014 and November 2014, 411 patients from 3 traditional Korean medical hospitals were asked to complete the BSQ-II. Each patient was independently diagnosed with BSS by two traditional Korean medical physicians from the same site. We estimated the internal consistency using Cronbach's ${\alpha}$ coefficient, the discriminant validity using the means score of BSS, and the predictive validity using logistic regression (sensitivity and specificity). Results : The BSQ-II had satisfactory internal consistency (Cronbach's ${\alpha}$ coefficient=0.765) and validity, with significant differences in the mean scores between the BSS($63.60{\pm}9.56$) and non-BSS groups($48.36{\pm}5.93$). The area under the receiver operating curve was about 98%, and the sensitivity and specificity were 91.4% and 94.9%, respectively. Conclusions : These results suggest that the CoRE-Ditec-BSQ-II is more reliable and valid instrument for estimating BSS than BSQ-I.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.33 no.2
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• pp.140-155
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• 2020

Objectives : The purpose of this study is to report the effectiveness of korean medical treatments on recurrent aphthous stomatitis(RAS) diagnosed as excess pattern(實證) based on symptoms of damum(痰飮), blood stasis(瘀血) and fire-heat(火熱). Methods : We treated a 61-year-old male patient who has RAS by korean medicine, pharmacopuncture and acupuncture treatment. These treatments were performed from 2020.01.22. to 2020.02.29. We have confirmed the improvement of ulcer lesions and pain. We recorded images that include change of symptoms. Results : After the treatments were done, the scores of numeric rating scale(NRS), oral health impact profile-14 (OHIP-14), oral assessment guide (OAG) and world health organization oral toxicity scale (WHO OTS) were decreased. The NRS score was decreased from 7 to 1. The OHIP-14 score was decreased from 30 to 14. The OAG score was decreased from 17 to 9. The WHO OTS score was decreased from 2 to 1. And ulcer lesions were clearly decreased. Conclusions : According to the result, korean medical treatments such as korean medicine, pharmacopuncture and acupuncture treatment, that are targeted at excess pattern(實證) caused by damum(痰飮), blood stasis(瘀血) and fire-heat(火熱) can be effective for the treatment of RAS.

• The Journal of Internal Korean Medicine
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• v.30 no.3
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• pp.525-533
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• 2009

Objectives : There are lots of reports that cardiovascular disease, including hypertension, cerebro-vascular accident, and coronary heart disease, is related to atherosclerotic changes. Increased serum levels of lipids could play a role in these changes. This study aimed to investigate the relationship between PWV and risk factors of cardiovascular disease, including serum lipid values. Methods : This study included 261 subjects ($49.32{\pm}11.79$ years, 112 male) who underwent PWV and serum lipid evaluation. We investigated the correlation between serum lipid values, blood pressure, body mass index (EMI) and PWV. Pearson's correlation and partial correlation analysis were applied to examine the relationship between PWV and risk factors of cardiovascular disease. Results : Serum triglyceride, total cholesterol, systolic blood pressure, and diastolic blood pressure were significantly correlated with PWV. Partial correlation coefficient adjusted by age yielded significant correlation between serum triglyceride, systolic blood pressure, diastolic blood pressure and PWV. Conclusion : In this study, it seems that there are significant relationships between PWV, triglyceride and blood pressure. We could suggest that PWV might have some relationships with Dam-eum and blood stasis in oriental theory.

• Journal of Acupuncture Research
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• v.22 no.4
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• pp.95-111
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• 2005

Objectives : The analysis of prognosis about lumbago classes is important for low back patients. This study was designed to show the clinical significance about lowback pain patients based on 10 classes lumbago ill Dong-Eui-Bo-Kham. Methods : To analyze classify 80 patients who had received the hospital treatment for low back pain, they were classified according to 10 classes lumbago in Dong-Eui-Bo-Kham. To estimate the efficacy of oriental medical treatment, we used Quardruple Visual Analog Scale (QVAS). Results & Conclusion :1. According To 10 classes lumbago in Dong-Eui-Bo-Kham, the largest group of lumbago was due to muscle strain in 30(37.5%) cases, the next was due to wind pathogen group in 18(22.5%) cases, due to blood stasis group in 16(20%), due to Kidney deficiency by 12(15.0%), due to retention of food group by 2(2.5%), the lumbago due to humidity pathogen group by 2(2.5%) in order. 2. By the results which puts out the statistics in lumbago classes on a objectivity treatment record, the Lumbago due to blood stasis, the lumbago due to kidney deficiency, the lumbago due to muscle strain, the lumbago due to wind pathogen, the lumbago due to retention of food, the lumbago due to humidity pathogen showed $3.6({\pm}0.68),\;2.83({\pm}0.84),\;3.13({\pm}0.78),\;2.67{\pm}(0.77),\;3.00,\;3.00$. 3. By the results which puts out the statistics in lumbago classes as a subjectivity treatment record, the Lumbago due to blood stasis, the lumbago due to Kidney deficiency, the lumbago due to muscle strain, the lumbago due to wind pathogen, the lumbago due to retention of food, the lumbago due to humidity pathogen changed from $8.19{{\pm}1.68),\;8.58{\pm}(1.08),\;7.80{\pm}(2.28),\;8.67({\pm}1.46),\;9.00({\pm}1.41),\;8.50({\pm}0.71)\;to\;2.81({\pm}1.91),\;4.17({\pm}2.52),\;2.43({\pm}1.63),\;3.00({\pm}1.85),\;2.00,\;3.00$.

• The Journal of Korean Obstetrics and Gynecology
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• v.15 no.4
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• pp.208-217
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• 2002

We had treated one melasma patient occurred by pregnancy with oriental medicine's method and got a good result. Melasma is often occured in pregnancy and dysmenorrhea. Most common pathology of melasma in oriental medicine is Yin deficiency with Fire and Blood Stasis. The Fire and Blood Stasis are made by Qi stagnation which is occurred by depression and stress. So we used the methods of promoting Qi and Blood, increasing Yin with clearing heat, and the result is very successful. We found out that Oriental Gynecologic therapy is most appropriate for treating woman's melasma, and could provide the treatment model.