• Title/Summary/Keyword: Blood vessel

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Hemodynamic Analysis of Blood Flows in the Extraembryonic Blood Vessels of Chicken Embryos (유정란 태아외부혈관 내부 혈액유동에 대한 혈류역학적 연구)

  • Lee, Jung-Yeop;Lee, Sang-Joon
    • 한국전산유체공학회:학술대회논문집
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    • 2008.03b
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    • pp.6-9
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    • 2008
  • Analyzing the characteristics of blood flow in the blood vessels is very important to diagnose the circulatory diseases. In order to investigate the hemodynamic characteristics in vivo, the measurements of blood flows inside the extraembryonic arterial and venous blood vessels of chicken embryos were carried out using an in vivo micro-PIV technique. The circulatory diseases are closely related with the formation of abnormal hemodynamic shear stress regions, thereby it is important to get blood velocity and vessel's morphological information according to the vessel configuration and the flow conditions. In this study, the flow images of RBCs in blood vessels were obtained using a high-speed CMOS camera with a spatial resolution of approximately 14.6${\mu}$m${\times}$14.6${\mu}$m in the whole circulation network of blood vessels. The blood flows in the veins and arteries show steady laminar and unsteady pulsatile flow characteristics, respectively. The mean blood flows merged (in veins) and bifurcated (in arteries) smoothly into the main blood vessel and branches, respectively, without any flow separation or secondary flow which accompanying large variation of shear stress. Vorticity was high in the inner regions for both types of vessels, where the radius of curvature varied greatly. The instantaneous flows in the arterial blood vessels showed noticeable pulsatility due to the heart beat, and the main features of the velocity waveforms, including pulsatile shape, retrograde flow, mean velocity, maximum velocity and pulsatile frequency, were significantly dependent on the pulsatile condition which dominates the arterial blood flow. In near future, these in vivo experimental results of blood flow measured in various extraembryonic blood vessels would be very useful to understand the hemodynamic characteristics of human blood flows and various blood flow researches for clinically useful hemodynamic discoveries as well.

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CFD Analysis on Stent Shape to Reduce Blood Flowing into Cerebral Aneurysm (뇌동맥류 혈액유입 저감을 위한 스텐트 형상에 관한 전산유체해석)

  • Yeo, Dong-Hyeon;Park, Dong-Gyu;Byon, Sang-Min
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.16 no.1
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    • pp.42-50
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    • 2017
  • A cerebral aneurysm is a ballooning arising from a weakened area in the wall of a blood vessel in the brain. In this study, the flow analysis of the blood vessel, including the cerebral aneurysm and the stent, was conducted to investigate the effect of the stent shape on reduction of blood flowing into the cerebral aneurysm. We used the Carreau model to describe Non-Newtonian behaviors of blood flow. Two kinds of stents, which had different cross angles were modelled by the commercial CAD program and the geometries of those stents were reflected in the analysis domain of the blood vessel. From the results of the flow analysis, we found that the blood flowing into the cerebral aneurysm was decreased as the cross angle of the stent was decreased.

Review on Hyolmaek(血脈) through Hwangjenaegyeong Youngchu (${\ll}$ 제내경(黃帝內經).영추(靈樞)${\gg}$를 통한 혈맥소고(血脈小考))

  • Kang, Mi-Suk
    • Journal of Acupuncture Research
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    • v.27 no.6
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    • pp.111-114
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    • 2010
  • Objects : This study focused on the concept of Hyolmaek in Hwangjenaegyeong Youngchu. Methods : We researched the words "Hyolmaek" through Hwangjenaegyeong Youngchu. According to meanings of Hyolmaek in sentence, we classified Hyolmaek. Results : In Hwangjenaegyeong Youngchu, the meanings of Hyolmaek(血脈)are follows. 1. There were many meanings of Hyolmaek In Hwangjenaegyeong Youngchu. 2. Hyolmaek means blood vessels, Lakmaek, blood circulation, extravasated blood, and etc. and it represents blood vessel systems.

Review on Nutrient and Blood (영(營)과 혈(血)에 대한 고찰)

  • Eom, Dong-Myung;Song, Ji-Chung;Jeong, Heon-Young
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.24 no.4
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    • pp.553-558
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    • 2010
  • Nutrient and Blood are really common conceptions in Traditional Korean Medicine(TKM). However, those are used in mixed. not only because of their common points but users who doesn't have clear classifications between them. Therefore, I will explain those owns by explaining origins, places of origons, pathway, circulations, organs related to them and color. In addition, I will try to explain thi things in common without conceptions of their own. As a result, the first, nutrient is what is originated from water and food at middle energizer and circulated in meridian vessel by control of spleen. The second, blood is what is originated from qi of water and food and circulated in blood vessel by control of heart and its color is red. The third, nutrient blood is what is originated from water and food or qi of water and food and circulated in meridian or blood vessel by control of spleen and heart. Also it is red and its function is nourishing human body. The name of Nutrient blood is a new term that I made and it is different from nutrient or blood. Also it is different from nutrient and blood. Nutrient blood is combination by conceptions, nutrient and blood is combination by word itself.

Efficient Generation of Spatiotemporal Images for Leukocyte Motion Detection in Microvessels

  • Kim, Eung Kyeu;Jang, Byunghyun
    • IEIE Transactions on Smart Processing and Computing
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    • v.6 no.2
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    • pp.76-84
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    • 2017
  • This paper presents an efficient method for generating spatiotemporal images in order to detect leukocyte motion in microvessels. Leveraging the constraint that leukocytes move along the contour line of the blood vessel wall, our proposed method efficiently generates spatiotemporal images for leukocyte motion detection. To that end, translational motion caused by in vivo movement is first removed by a template matching method. Second, the blood vessel region is detected by an automatic threshold selection method in order to binarize temporal variance images. Then, the contour of the blood vessel wall is expressed via B-spline function. Finally, using the detected blood vessel wall's contour as an initial curve, the plasma layer for the most accurate position is determined in order to find the spatial axis via snake, and the spatiotemporal images are generated. Experimental results show that the spatiotemporal images are generated effectively through comparison of each step with three images.

Change of blood pressure end vasorelaxation on EAE-induced lewis rat

  • Bong su Kang;Park, Young shim;In hoi Huh
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1996.04a
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    • pp.194-194
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    • 1996
  • Pathogenesis of experimental allergic encephalomyelitis was involved with infection, inflammatory reaction, immune reaction etc. We studied on relation of blood vessel system and EAE. So, we measured blood pressure, heart rate and relaxation of isolated blood vessel in control and EAE-induced lewis rats. Blood pressure was decreased before EAE clinical sign (0-20day), but was increased from 23day. In isolated blood vessel, acetylcholine-treated relaxation was different on control, maximum EAE stage, recovery stage. Acetylcholine-treated relaxation was reduced 30% in recovery stage. but, sodium nitroprusside had similar relaxation reaction.

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An Ultrasonic Vessel-Pattern Imaging Algorithm with Low Computational Complexity (낮은 연산 복잡도를 지니는 초음파 혈관 패턴 영상 알고리즘)

  • Um, Ji-Yong
    • Journal of IKEEE
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    • v.26 no.1
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    • pp.27-35
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    • 2022
  • This paper proposes an ultrasound vessel-pattern imaging algorithm with low computational complexity. The proposed imaging algorithm reconstructs blood-vessel patterns by only detecting blood flow, and can be applied to a real-time signal processing hardware that extracts an ultrasonic finger-vessel pattern. Unlike a blood-flow imaging mode of typical ultrasound medical imaging device, the proposed imaging algorithm only reconstructs a presence of blood flow as an image. That is, since the proposed algorithm does not use an I/Q demodulation and detects a presence of blood flow by accumulating an absolute value of the clutter-filter output, a structure of the algorithm is relatively simple. To verify a complexity of the proposed algorithm, a simulation model for finger vessel was implemented using Field-II program. Through the behavioral simulation, it was confirmed that the processing time of the proposed algorithm is around 54 times less than that of the typical color-flow mode. Considering the required main building blocks and the amount of computation, the proposed algorithm is simple to implement in hardware such as an FPGA and an ASIC.

A Study on the Blood-Letting Therapy in Elementary Questions (("황제내경소문(黃帝內經素問)" 중(中) 사혈(瀉血)에 관한 연구(硏究))

  • Lee, Jun-Geun
    • Journal of the Korean Institute of Oriental Medical Informatics
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    • v.14 no.1
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    • pp.19-42
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    • 2008
  • Blood-Letting Therapy is a rational and ecological medical treatment by which we can heal most of the diseases by removing the static blood which precipitates in the blood vessel and blocks the flowing of blood. And the static blood is the generic term for the injurious, bad, dead and precipitated blood which is blocked the capillary vessel. The Yellow Emperor's Canon of Internal Medicine says that "the patient is treated with drugs internally and stone acupuncture externally. "In the old texts, the blood-letting therapy is mentioned as blood-letting, network vessel pricking, bloodletting, pricking, and arousing pulses etc and it is noted down as the method of network vessel pricking in 'On the Application of Needles' of Spiritual Pivot. Nine-pricking therapy, twelve-pricking therapy and five-pricking therapy are recorded in the methods of network vessel pricking and among them, the method of squeezing blood after pricking the affected part is explained as the network vessel pricking. There are four methods of network vessel pricking, pricking, picking, cluster needling and scatter-pricking and they are fluidly applied to the various symptoms of diseases. In 'On Discriminative Treating for Patients of Different Regions' in Elementary Questions, Ki-baek emphasizes "most of the local people, there are black in skin and loose in striate, and their diseases are mostly of carbuncle kind. It is suitable to treat the disease with stone therapy to prick with stone, so the stone therapy is transmitted from the east. "And in 'On the Corresponding Relation Between the Eum and Yang of Man and All Things' in Elementary Questions, when the Emperor asked Ki-Back, he answered "sthenia means the sthenia of evil, and deficiency means the deficiency of healthy energy. When the blood is sthenic, the evil should be discharged by pricking when out letting the blood; deficiency of vital energy is the asthenia of channels and network vessels, so the energy should drain from the channel which is not deficient, to replenish. "And in this case we can use the methods of 'Breaking out the static bloods', 'driving out the static bloods', blood-letting'. With this we can infer that the blood-letting therapy is made use of the important medical treatments from the ancient times. Especially in referring to the principles of treatment in The Yellow Emperor's Canon of Internal Medicine, it mostly alluded to acupuncture therapies and only eleven times to medicinal treatments. This is to verify that the blood-letting therapy formed the foundation of the medical art. In Dong's Therapy of Acupuncture-Moxibustion and Bloodletting, Dong Kyeong-Chang gave emphasis on the points that there must be extravasated bloods without exception in the serious illnesses which is old, unnatural, accompanying acute pains and so we can revive our body‘s sprit by circulating 'gi' and static blood piled up in the network vessel, regulating the weakness and strength, and controling the disharmony of the internal organs. The blood-letting therapy has effect on the orifice in emergency, such as fore draining, freeing network vessels, harmonizing gi and blood, relieving pain, dispersing swelling and concretion, sedation, resolving toxin as well as strengthening the heart, relieving itching. So it has distinguished effect on all kinds of medical treatment to the modern people. But by the change of social customs and the confucianism of confucius - it is widely spread on the period of North and South Dynasties, 'Wi' and 'Jin' in china and the period of the Three States in korea - The blood-letting therapy which was regarded as the most important medicinal treatment withered rapidly. And Confucius accentuated the importance of our body and all its members, loyalty and filial piety and banned any damage of our body under no circumstances. As a result of it, the therapy of blood-letting had a rapid decrease and barely kept itself in existence in both countries. What is worse, at the period of Japanese colonial rule of korea and our nation's founding of early stage, it has been withered by the high-handed policy to change Oriental Medicine into modern medical science. So the therapy of blood-letting barely kept itself in existence in some Buddhist temples. Another case, it has handed down as a old-fashioned quick fix in folk remedies. But all kinds of the contamination of heavy metals and the misuses of antibiotics are widely spread nowadays, which increased diseases of adult people and incurable diseases as modern society unavoidably made its way into a highly industrial society. To make us more miserable, the western medical science - the antibiotics and surgical operation medical science - already reveals itself into a limit. The necessity of a new medical science which can give a security to the patients who are suffering from the diseases of adult people and the incurable diseases is especially come into the force nowadays. In view of the results after bibliographically studying on the blood-letting Therapy in Elementary Questions of the Yellow Emperor's Canon of Internal Medicine, the blood-letting therapy has acted for the important Oriental medicinal science and has been clarified the prominent effects on the diseases of adult people and the incurable diseases. So it is regarded as an appropriate thing that we lay out a determined theory of the blood-letting therapy and of course prevent the unwanted side effects from inappropriate medicinal treatments, and make full use of clinic by elevating the curative value and that we win back our self-respect of medical treatment which is dominated from the western medical science and ultimately contribute to national medical welfare.

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