• Journal of Preventive Medicine and Public Health
• /
• 제26권3호
• /
• pp.332-346
• /
• 1993

성인 남성들에서 여가시간의 육체적 활동량의 분포를 파악하고 관상동맥질환의 위험인자들과의 관련성을 보기위해 경상북도에 소재하는 일개 제철회사의 남성 근로자 277명을 연구대상자로 선정하였다. CARDIA 연구의 Physical Activity History questionnaire를 변형한 설문지를 이용하여 연구대상자들의 여가시간의 육체적 활동에 대해 면담조사하였다. 공복시 혈액 5ml를 채취하여 혈청 총콜레스테롤, 중성지방 및 혈당량을 측정하였고, 신장, 체중 및 혈압을 측정하였다. 흡연습관과 음주습관, 교육 수준 및 그 밖의 사항들은 설문지를 이용하여 면담조사하였다. 연구대상자들의 여가시간의 육체적 활동에 의한 에너지 소모량의 기하 평균치는 212.80 kcal/week이었고, 전체 대상자 중 여가시간에 2,000 kcal/week이상 육체적 활동을 하는 사람의 비율은 22. 4%이었다. 설문지의 항목들 중 대상자들이 여가시간에 하는 운동으로 가장 많은 것은 산보나 등산, 조깅 혹은 달리기 등이었다. 전체 대상자들에서 연령별, 교육수준별, 근무기간별, 흡연 및 음주습관별 주당 여가시간의 육체적 활동량이 유의한 차이를 보이지 않았으나, 작업 중 격렬한 노동을 하는 사람들이 안 하는 사람들에 비해 주당 여가시간의 육체적 활동량이 많은 것으로 나타났다(p<0.05). 여가시간의 육체적 활동량과 관상동맥질환의 위험인자들과의 관련성을 보고자 여가시간의 육체적 활동량을 중등도 이상의 활동을 전혀 안 하는 경우, 총 활동량이 2,000 kcal/week 미만인 경우 그리고 총 활동량이 2,000 kcal/week 미만인 경우의 세 군으로 나눈 후 BMI, 수축기 및 이완기혈압, 혈청 총콜레스테롤, 중성지방, 공복시 혈당량의 평균을 비교하였으나 통계적으로 유의한 차이를 보인 것은 없었다.

• 대한간호학회지
• /
• 제29권1호
• /
• pp.97-106
• /
• 1999

This study was designed to investigate the effect of a hand massage program on anxiety and immune function in patients during cataract surgery. The hand massage program, in this study, consisted of hand massage and hand-holding. The subjects were sixty-three patients, thirty for the experimental and thirty-three for the control group, who were admitted at Kang Nam St. Mary's Hospital for cataract surgery. This study was carried out from December 10, 1997 to February 26, 1998. The level of anxiety as measured by the Visual Analogue Scale, systolic blood pressure, diastolic blood pressure, and pulse rate were measured before, after hand massage, and after hand-holding. Epinephrine, norepinephrine, cortisol, blood sugar levels, neutrophil, lymphocyte, and natural killer cell percentages also were measured before hand massage and five minutes before the end of the operation. Data were analyzed by t-tests, ANCOVA, repeated measures ANOVA, and Bonferroni multiple comparisons. The results were as follows : 1) After hand massage, psychological anxiety levels decreased significantly compared with before hand massage in the experimental group, not in the control group. After hand holding, there were significant decrease in both groups. 2) There were not significant differences on systolic blood pressure, diastolic blood pressure, and pulse rates in both groups. 3) The hand massage program decreased epinephrine, norepinephrine, and cortisol significantly in the experimental group, and increased epinephrine, norepinephrine, and cortisol in the control group. 4) There were no differences in blood sugar levels, neutrophil and lymphocyte percentages in white blood cells after the hand massage program. However, natural killer cells in lymphocytes were significantly increased in the experimental group. These findings indicate that a hand massage program could be a effective nursing intervention in decreasing the psychological and physiological anxiety levels and improving immune function in clients having cataract surgery under local anesthesia.

• 한국동물생명공학회지
• /
• 제36권4호
• /
• pp.203-211
• /
• 2021

Diabetic mellitus (DM) is a carbohydrate metabolic disorder that involves high blood sugar because insulin works abnormally. Type 2 diabetes accounts for most of them. However, diabetes treatments such as GLP-1 and DPP-4 inhibitors commonly caused side effects including gastrointestinal disorders. Grifola frondosa (G. frondosa) revealed various pharmacological effects in recent studies. It has a variety of anti-cancer polysaccharides through host-mediated mechanisms. D-fraction in G. frondosa has apoptotic effects, promoting myeloid cell proliferation and differentiation into granulocytes-macrophages. It has also been shown to reduce the survival rate of breast cancer cells. Though, no further study has been conducted on the specific effects of G. frondosa in the db/db mouse. Therefore, we would like to research the blood glucose improving effect of G. frondosa, a natural material, in type 2 diabetes model mouse, in this study. G. frondosa was administered to the disease model mouse (BKS.Cg-+Lepr^db/+Lepr^db/OlaHsd) for 8 weeks to monitor weight and blood glucose changes every week. And we evaluated anti-diabetes effects by checking biomarker changes shown through blood. Experiment did not show statistically significant weight differences, but control groups showed significantly higher weight gain than G. frondosa administered groups. We collected blood from the tail veins of the db/db mouse each week. As a result, the lowest blood sugar level was shown in the 500 mg/kg group of G. frondosa. Glucose in the blood was examined with HBA1c, and 7.8% was shown in the 500 mg/kg administration group, lower than in other groups. These results suggest the potential improvements of diabetes in G. frondosa.

• BMB Reports
• /
• 제38권2호
• /
• pp.211-217
• /
• 2005

Cordyceps, an entomopathogenic fungus, contains many health-promoting ingredients. Recent reports indicate that the consumption of cordyceps helps reduce blood-sugar content in diabetics. However, the mechanism underlying this reduction in circulatory sugar content is not fully understood. Methanolic extracts were prepared from the fruiting bodies of Paecilomyces tenuipes, and 4-beta acetoxyscirpendiol (4-ASD) was eventually isolated and purified. $Na^+$/Glucose transporter-1 (SGLT-1) was expressed in Xenopus oocytes, and the effect of 4-ASD on SGLT-1 was analyzed utilizing a voltage clamp and by performing 2-deoxy-D-glucose (2-DOG) uptake studies. 4-ASD was shown to significantly inhibit SGLT-1 activity compared to the non-treated control in a dose-dependent manner. In the presence of the derivatives of 4-ASD (diacetoxyscirpenol or 15-acetoxyscirpendiol), SGLT-1 activity was greatly inhibited in an 4-ASD-like manner. Of these derivatives, 15-acetoxyscirepenol inhibited SGLT-1 as well as 4-ASD, whereas diacetoxyscirpenol was slightly less effective. Taken together, these results strongly indicate that 4-ASD in P. tenuipes may lower blood sugar levels in the circulatory system. We conclude that 4-ASD and its derivatives are effective SGLT-1 inhibitors.

• International Journal of Internet, Broadcasting and Communication
• /
• 제12권3호
• /
• pp.102-107
• /
• 2020

Recently, the number of people visiting the hospital is increasing due to diabetes. According to the Korean Diabetes Association, statistically, 1 in 7 adults over the age of 30 are suffering from diabetes. As such, diabetes is one of the most common diseases among modern people. In this paper, in addition to blood sugar, which is widely used for diabetes awareness, BMI, which is known to be related to diabetes, triglycerides and cholesterol that cause various complications in diabetics it was studied using random forest techniques and decision trees known to be effective for classification. The importance of each element was confirmed using the results and characteristic importance derived using two techniques. Through this, we studied the diabetes-related relationship between BMI, triglyceride, and cholesterol as well as blood sugar, a factor that diabetic patients should pay much attention to.

• 한국식품영양학회지
• /
• 제9권2호
• /
• pp.189-200
• /
• 1996

The purpose of this study was to find the effect of honey on the sugar metabolism In Sprague-Dawley rats. All experimental rats were fed ad libitum, for seven weeks, 68% saccharide diet anti 10% or 20% honey from acacia, sumac and miscellaneous flower honey, respectively, and sucrose. The amount of glucose in whole blood was increased in all groups fed with honey except the group fed with 10% sumac honey solution. The amount of fructosamine in serum of rat taken diet with honey solution was increased in comparison with normal group, control group, sucrose group. The amount of fructosamine in serum of rat taken diet with honey solution was high in order of sumac honey > miscellaneous flower honey > acacia honey. The amount of lactate and pyruvate in whole blood of rat taken diet with sucrose group or honey group were decreased in comparison with the normal group and control group. The amount of $\beta$-hydroxybutyrate in serum of rat taken diet with sucrose or honey was increased in comparison with the normal group, control group.

• Journal of Chest Surgery
• /
• 제21권3호
• /
• pp.558-562
• /
• 1988

Localized mesothelioma is a primary pleural tumor that induces hypoglycemia rarely. We experienced a case of the localized mesothelioma that induced hypoglycemia. The patient was 70 year-old man who was admitted to Severance Hospital because of general weakness and mental confusion in morning before breakfast. He was found to have low level of fasting blood sugar and C-peptide, but had normal serum insulin level. After excision of the tumor, the patient was free from symptoms of hypoglycemia, and fasting blood sugar level was returned to normal range. The most likely speculation of causing hypoglycemia by the mesothelioma was thought to be that the tumor did not secrete insulin itself but the undetectable insulin-like substance and/or antigluconeogenic substances. During the follow up, 5 months after surgical removal of tumor, the patient was in a good condition without symptoms of hypoglycemia.

• 대한약리학회지
• /
• 제8권2호
• /
• pp.49-54
• /
• 1972

The component and pharmacologic action on Dianthus sinensis L. were investigated as follows: 1) The components of Dianthus sinensis L. were suggested 8 kind of components by means of thin layer chromatography and paper chromatography. The one of them were suggested as a steroidal saponin by means of IR-spectrum and Liebermann-Burchard, Salkowiski, $SbCl_3$ reaction. 2) Sodium level in serum were reduced by administration of the sample to the rabbits, while in urine were elevated. 3) Blood sugar level of normal rabbits administered with sample, no significant variation were detected. 4) When the hyperglycemic rabbits treated with alloxan were administered sample, blood-sugar level were significantly decreased than control group.

• The Korean Journal of Pain
• /
• 제9권1호
• /
• pp.275-278
• /
• 1996

The placement of epidural catheter may cause complications such as epidural hematoma, epidural abscess and neural damage. Among the above complications, epidural abscess is a rare but serious complication. This report pertains to a diabetic metlitus patient who developed spinal epidural and subdural abscess after continuous epidural catheterization for management of pain caused by reflex sympathetic dystrophy. The patient experienced urinary incontinence, as a neurologic sign, 8 days after epidural catherization. In was considered that the poor prognosis was due to a combination effects of a delayed visit to the hospital for treatment, rapid progression of abscess and uncontrolled blood sugar level. We therefore recommend aseptic technique and proper control of blood sugar level to prevent infection during and after epidural catheterization for diabetic patients. Early diagnosis of epidural abscess following surgical procedure must be required to avoid sequelae.

• 대한약리학회지
• /
• 제5권2호
• /
• pp.81-86
• /
• 1969

Alloxan is a diabetogenic agent which destroys the beta-cell of the Langerhan's islet of pancreas and it disturbs the secretion of insulin. It is known that alloxan interfers with the hepatic enzyme activity and some aspect of the other metabolism. The author attempted to investigate the influence of reserpine upon the serum transaminase activity, blood sugar and serum total cholesterol contents of rabbit treated alloxan. The results obtained were summarized as follows; 1. The serum GOT and GPT activity of alloxanized rabbit pretreated with reserpine showed marked decrease compared with alloxan control group. 2. The blood sugar level of alloxanized rabbit pretreated with reserpine showed lower than the alloxan control group. 3. The total cholesterol level of alloxanized rabbit pretreated with reserpine was lower than that of alloxan control group.