• 제목/요약/키워드: Blockage effect

검색결과 184건 처리시간 0.024초

Experimental study on TLDs equipped with an upper mounted baffle

  • Shad, Hossein;Adnan, Azlan bin;Vafaei, Mohammadreza;Behbahani, Hamid Pesaran;Oladimeji, Abdulkareem M.
    • Smart Structures and Systems
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    • 제21권1호
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    • pp.37-51
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    • 2018
  • Tuned Liquid Dampers (TLDs) have gained wide acceptance as a system for structural control and energy dissipation. However, they face limitation caused by low damping in deep water, which affects their efficiency. Another problem with deep water TLDs is that not all water depth participates in energy dissipation. This paper investigated the effect of upper mounted baffles on the effectiveness of TLDs. The Vertical Blockage Ratio (VBR) of baffles ranged from 10% - 90%. The TLD (with and without baffle), structure, and combined structure with TLD (with and without baffles) were subjected to free and harmonic forced vibrations. Results indicated that baffles could significantly enhance the energy dissipation of TLDs, thus reducing structural responses more than structures equipped with ordinary TLDs. It was found that, there was an optimum value of VBR in which the TLD's efficiency was maximized. When TLD had an appropriate VBR, the structural acceleration and displacement responses were suppressed significantly up to 51% and 56%, respectively.

Oridonin Suppresses Proliferation of Human Ovarian Cancer Cells via Blockage of mTOR Signaling

  • Xia, Rong;Chen, Sun-Xiao;Qin, Qin;Chen, Yan;Zhang, Wei-Wei;Zhu, Rong-Rong;Deng, An-Mei
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권2호
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    • pp.667-671
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    • 2016
  • Oridonin, an ent-kaurane diterpenoid compound isolated from the traditional Chinese herb Rabdosia rubescens, has shown various pharmacological and physiological effects such as anti-tumor, anti-bacterial, and anti-inflammatory properties. However, the effect of oridonin on human ovarian cancer cell lines has not been determined. In this study, we demonstrated that oridonin inhibited ovarian cancer cell proliferation, migration and invasion in a dose-dependent manner. Furthermore, we showed oridonin inhibited tumor growth of ovarian cancer cells (SKOV3) in vivo. We then assessed mechanisms and found that oridonin specifically abrogated the phosphorylation/activation of mTOR signaling. In summary, our results indicate that oridonin is a potential inhibitor of ovarian cancer by blocking the mTOR signaling pathway.

평균유동이 있는 유체 공급배관내 오리피스의 압력섭동 감쇠 특성 (Pressure-Oscillation Damping Characteristics of an Orifice in a Fluid Feeding Line with Mean Flow)

  • 이태영;김철진;손채훈
    • 한국추진공학회:학술대회논문집
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    • 한국추진공학회 2009년도 제33회 추계학술대회논문집
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    • pp.359-362
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    • 2009
  • 유체 공급 배관 내에 오리피스를 설치하여, 압력진동의 감쇠효과를 수치해석 및 실험을 통하여 조사하였다. 압력진동이 작다는 가정에 기초하여 오리피스의 음향학적 감쇠 효과를 실험적으로 확인 하였으며, 평균 유동이 있을 경우 관찰되는 감쇠 특성을 수치적으로 조사하였다. 오리피스의 위치에 따른 압력진동의 마디, 즉 속도 진동의 배가 되는 위치에 오리피스를 설치할 때 가장 효과적인 압력 진동이 감쇠 되었다. 배관 내 평균 유속이 있을 경우 공진주파수가 감소하였고, 이에 따라 최적 감쇠 효과를 갖는 오리피의의 위치도 변화함을 알 수 있었다.

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비포화 흐름에서 모세관 이력현상 모형의 고찰 - 모형의 개발 - (Capillary Hysteresis Model in Unsaturated Flow - Development of Model -)

  • 박창근;선우중호
    • 대한토목학회논문집
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    • 제13권4호
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    • pp.131-140
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    • 1993
  • 기존의 Mualem의 Model III-1에서 공기가 공극으로 진입할 때 이에 대한 공극들의 방해효과를 설명하는 가중치(加重値) $P_a({\theta})$가 무차원 공극반경과 선형적 관계를 가진다는 가정을 바탕으로 하여 모형의 검정을 위하여 한 개의 주곡선이 필요한 새로운 모형을 개발하였다. 개발된 모형은 모형의 검정을 위하여 기존에 제시된 바 있는 한 개의 주곡선이 필요한 모형들보다 실측치를 잘 모의하며, 한쌍의 주곡선이 필요한 영역모형중에서 이력현상을 모형화하는 목적에 가장 부합한 Model III-1과의 비교에서 개발된 모형은 거의 같은 정확성을 가지면서 실측자료를 재현하고 있음을 알 수 있었다. 또한 개발된 모형은 비포화 흐름을 해석할 때 효율적으로 적용될 수 있음을 알 수 있었다.

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고체 입자첨가가 수소화염의 열특성에 미치는 영향에 관한 실험적 연구 (An Experimental Study about The Effect of Solid Particle Seeding on Thermal Characteristics of Hydrogen Flame)

  • 김중주;백승욱;김한석;최준원
    • 대한기계학회논문집B
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    • 제26권11호
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    • pp.1503-1512
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    • 2002
  • From the view of the environmental protection against the use of fossil fuels, a great of efforts have been exerted to find an alternative energy source. Hydrogen may become an alternative However the product species of the hydrogen flame is only $H_2O$, which emits only non-luminous radiation so the radiation from it is much smaller than that for a hydrocarbon flame. In this study, the authors designed and fabricated a laboratory scale test furnace to study thermal characteristics of hydrogen-air diffusion flame. In addition. the effects of addition of reacting as welt as non-reacting solid particles were experimentally investigated. Among the total heat flux to the wall, about 75 % was occupied by radiation while 25% by convection. When the aluminum oxide (Al$_2$O$_3$) particles were added, the radiative heat flux was reduced due to heat blockage effects. On the other hand, the total as well as the radiative heat flux was increased when the carbon particles were seeded, since the overall temperature increased. The effects of swirl and excess air ratio were also examined.

1단 축류 터빈의 비정상 내부유동특성에 관한 2차원 해석 (II) (Two-Dimensional Analysis of Unsteady Flow Through One Stage of Axial Turbine (II))

  • 박준영;엄인식;백제현
    • 대한기계학회논문집B
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    • 제25권11호
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    • pp.1518-1526
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    • 2001
  • In this paper, the mechanism of unsteady potential interaction and wake interaction in one stage axial turbine is numerically investigated at design point in two-dimensional viewpoint. The numerical technique used is the upwind scheme of Van-Leer's Flux Vector Splitting (FVS) and Cubic spline interpolation is applied on zonal interface between stator and rotor. The inviscid analysis is used to embody the influence of potential interaction only and viscous analysis is used to embody the influences of both potential interaction and wake interaction at the same time. The potential-flow disturbance from the stator into a rotor passage and the periodic blockage effect of rotor produce the unsteady pressure on the blade surface in inviscid analysis. After the wake is cut by rotor, two counterrotating votical patterns flanking the wake centerline in the passage are generated. So, these phenomena magnify the unsteady pressure in viscous analysis than that in inviscid analysis. The resulting unsteady forces on the rotor, generated by the combined interaction of the two effects by potential and wake interaction, are discussed.

Validation of the numerical simulations of flow around a scaled-down turbine using experimental data from wind tunnel

  • Siddiqui, M. Salman;Rasheed, Adil;Kvamsdal, Trond
    • Wind and Structures
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    • 제29권6호
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    • pp.405-416
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    • 2019
  • Aerodynamic characteristic of a small scale wind turbine under the influence of an incoming uniform wind field is studied using k-ω Shear Stress Transport turbulence model. Firstly, the lift and drag characteristics of the blade section consisting of S826 airfoil is studied using 2D simulations at a Reynolds number of 1×105. After that, the full turbine including the rotational effects of the blade is simulated using Multiple Reference Frames (MRF) and Sliding Mesh Interface (SMI) numerical techniques. The differences between the two techniques are quantified. It is then followed by a detailed comparison of the turbine's power/thrust output and the associated wake development at three tip speeds ratios (λ = 3, 6, 10). The phenomenon of blockage effect and spatial features of the flow are explained and linked to the turbines power output. Validation of wake profiles patterns at multiple locations downstream is also performed at each λ. The present work aims to evaluate the potential of the numerical methods in reproducing wind tunnel experimental results such that the method can be applied to full-scale turbines operating under realistic conditions in which observation data is scarce or lacking.

터널진입시 비정상 유동특성이 고속전철의 공력성능에 미치는 영향에 관한 수치해석적 연구 (Numerical study on the effect of three-dimensional unsteady tunnel entry flow characteristics on the aerodynamic performance of high-speed train)

  • 정수진;김태훈;성기안
    • Journal of Advanced Marine Engineering and Technology
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    • 제26권5호
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    • pp.596-606
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    • 2002
  • The three-dimensional unsteady compressible Euler equation solver with ALE, CFD code, PAM-FLOW based on FEM method has been applied to analyze the flow field around the high speed train which is entering into a channel. From the present study, the pressure and flow transients were calculated and analyzed. The generation of compression wave was observed ahead of train and the high pressure in the gap between the train and the tunnel was also found due to the blockage effects. It was found that abrupt fluctuation in pressure exists in the region from train nose to shoulder of train corresponding to 10% of total length of train during tunnel entry. Computed time history of aerodynamic forces of train during tunnel entry show that drag coefficient rapidly rises and saturates at about non-dimensional time 0.31. The total increase of drag coefficient before and after tunnel entry is about 1.1%. Transient profile of lift force shows similar pattern to drag coefficient except abrupt drop after saturation and lift force in the tunnel increases 0.08% more than that before tunnel entry.

고체입자의 수소화염에 있어서의 열복사에 관한 연구 (A Study about The Effect of Radiation on Particle-Seeding Hydrogen Flame)

  • 최준원;백승욱;김중주;김한석
    • 한국연소학회:학술대회논문집
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    • 한국연소학회 2002년도 제25회 KOSCI SYMPOSIUM 논문집
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    • pp.129-139
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    • 2002
  • From the view of the environmental protection against the use of fossil fuels, a great of efforts have been exerted to find an alternative energy source. Hydrogen may become an alternative. However the product species of the hydrogen flame is only $H_2O$, which emits only non-luminous radiation so the radiation from it is much smaller than that for a hydrocarbon flame. In this study, the authors designed and fabricated a laboratory scale test furnace to study thermal characteristics of hydrogen-air diffusion flame. In addition, the effects of addition of reacting as well as non-reacting solid particles were experimentally investigated. Among the total heat flux to the wall, about 75% was occupied by radiation while 25 % by convection. When the aluminum oxide ($Al_2O_3$) particles were added, the radiative heat flux was reduced due to heat blockage effects. On the other hand, the total as well as the radiative heat flux was increased when the carbon particles were seeded, since the overall temperature increased. The effects of swirl and excess air ratio were also examined.

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Treatment of Lung Cancer-Related Intractable Hiccups Using Pulsed Radiofrequency: Clinical Experience

  • Cho, Suk Ju
    • Journal of Hospice and Palliative Care
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    • 제21권3호
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    • pp.104-107
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    • 2018
  • 딸꾹질은 대개의 경우에는 특별한 처치 없이도 고식적인 방법으로 멈추지만, 한 달 이상 지속되는 지속성 딸꾹질은 생명을 위협할 정도의 심각한 부작용을 초래한다. 특히 정확한 치료방법 또한 확립되어 있지 않고, 몇몇 보고에서 양측 횡격막 신경차단이 보고되어 있을 뿐이다. 56세 남환의 우측 횡격막을 침범한 말기폐암환자에서 발생한 난치성 지속성 딸꾹질에 대해 박동성 고주파술을 시행하여 좋은 치료 결과를 얻은 바, 문헌고찰과 함께 보고하고자 한다.