• 대한핵의학회지
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• 제32권6호
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• pp.482-489
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• 1998

목적: 방사성 동위원소 뇌조조영술은 자발성 두 개 내 저압환자의 체위성 두통과 저뇌척수압의 병태생리를 이해하는데 도움을 줄 수 있다. 저자들은 이 질환의 방사성 동위원소 뇌조조영술의 특징적인 소견을 알아보고자 하였다. 대상 및 방법: 자발성 두개내 저압으로 진단되어 방사성 동위원소 뇌조조영술을 시행한 15명을 대상으로 하였다. 뇌조조영술은 Tc-99m DTPA 111-222 MBq를 요추천자를 통해 지주막하강에 투여한 후 감마카메라로 30분부터 2시간 이내에 방광을 포함한 요추부와 경흉추부의 전면상과 측면상을 얻었고, 4, 6, 24시간에 두부와 경흉추부의 전면상과 측면상을 얻었다. 방광 내 방사성 추적자의 조기 배설유무, 척수강 내 방사성의 이동속도, 연조직 섭취정도, 그리고 대뇌궁융부로의 이동 지연 등을 분석하였다. 결과: 방사성 동위원소 뇌조조영술 소견은 대뇌궁융부로의 방사성 추적자의 이동지연(14/15), 연조직의 섭취증가(11/15), 방광 내 방사성 추적자의 조기 출현(13/13) 등이 있었고 뇌척수액의 누출을 시사하는 척수경막강 주위의 방사성 추적자의 국소 집적도 4예에서 있었다. 결론: 방사성 추적자의 이동 지연과 연조직의 섭취증가 및 방광 내 방사성 추적자의 조기 출현 등이 특징적으로 관찰되었고, 이러한 뇌조조영술 소견은 자발성 두개 내 저압의 주된 병태생리가 뇌척수액의 누출임을 시사하는 것으로 판단되었으며, 방사성 추적자 이동의 역동적 측면을 잘 평가하기 위해서는 방광과 연조직을 포함한 30분 영상과 다발적인 연속영상을 획득하는 것이 필요하다고 생각된다.

• 한국임상수의학회지
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• 제32권1호
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• pp.115-119
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• 2015

An 11-year-old spayed female maltese was presented for abdominal distention, dysuria and dyschezia. Panting and heart murmur was found and abdominal palpation was difficult due to increased abdominal pressure. A soft tissue mass, $6{\times}3cm$ in size, was identified radiographically in pelvic canal, displacing the descending colon to the medioventral direction and the urinary bladder cranially. On ultrasonography, the mass consisted of homogeneous hypoechoic parenchyma containing the focal hyperechoic region ($1.6{\times}1.5cm$). The mass had distinct margin and no connection with adjacent organs. It was considered as a mass originating from the retroperitoneal cavity. Additional diagnostic procedures were not advanced because of the owner's request, and only a surgical excision of the mass was performed to alleviate the dysuria and dyschezia. Histopathologic examination and immunohistochemistry determined the mass as a soft tissue sarcoma and excluded hemangiosarcoma and osteosarcoma, both are the most common types of the retroperitoneal tumors. This report described non-vascular soft tissue sarcoma originating from the retroperitoneal cavity in a maltese dog.

• 전기학회논문지
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• 제56권8호
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• pp.1424-1429
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• 2007

This paper presents a simple and reliable one-touch type multi-immunosensing lab-on-a-chip (LOC) detecting antibodies as multi-disease markers using electrochemical method suitable for a portable point-of-care system (POCS). The multi-stacked LOC consists of a PDMS space layer for liquids loading, a PDMS valve layer with 50 im in height for the membrane, a PDMS channel layer for the fluid paths, and a glass layer for multi electrodes. For the disposable immunoassay which needs sequential flow control of sample and buffer liquids according to the designed strategies, reliable and easy-controlled on-chip operation mechanisms without any electric power are necessary. The driving forces of sequential liquids transfer are the capillary attraction force and the pneumatic pressure generated by air bladder push. These passive fluid transport mechanisms are suitable for single-use LOC module. Prior to the application of detection of the antibody as a disease marker, the model experiments were performed with anti-DNP antibody and anti-biotin antibody as target analytes. The flow test results demonstrate that we can control the fluid flow easily by using the capillary stop valve and the PDMS check valves. By the model tests, we confirmed that the proposed LOC is easily applicable to the bioanalytic immunosensors using bioelectrocatalysis.

• 한국응급구조학회지
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• 제24권3호
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• pp.147-154
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• 2020

Purpose: The purpose of the study was to investigate traumatic urethral injury in a 63-year-old patient with hematuria. Methods: A hematuria patient was transferred by paramedics. At the time of the visit, the patient's blood pressure (151/91mmHg), pulse rate (86/min), body temperature (37.1℃), and other vital signs were stable. Their KTAS (Korean Triage and Acuity Scale) was Level 4. The patient had no damage to the injured area, but a large contrast defect was observed between the prostate urethra and the bladder in urethral angiography performed due to persistent hematuria and pain in the injured area. Results: Following radiological evaluation of a suspected liposarcoma or neuroma mass of the prostate urethra, the mass was removed through urethral tumor resection. The result of histologic evaluation provided a diagnosis of highly differentiated invasive urethral cell carcinoma that had invaded the muscle layer. The patient was given additional treatment for urethral cancer but was rejected and is currently being followed. Conclusion: The prognosis for urinary tract cancer has distinct differences for patients with lymph node metastasis and tumor characteristics. The presence or absence of urethral cancer should be confirmed through angiography, CT, MRI, and cystoscopy.

• 지역사회간호학회지
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• 제19권2호
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• pp.157-166
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• 2008

This study was conducted with whole home care nurses nationwide to provide secondary analyzed data to understand on their usage of medical equipments and their need of them for a month. This study found that treatments given by home care nurses were nelaton catheterization, bladder washing/urethral washing, newborn care, exchange and care for nasogastric tube and suction in that order of frequency. Second, instruments and equipments used for home care were reported to be stethoscope, patient monitor, blood pressure measuring equipment, air flotation mattresses, beds for patients, mattresses, suctioning device sets, enteral feeding equipment and dressing set in that oder of frequency. Moreover, need assessment of medical instruments and equipments showed renal dialysis was most needed and patient monitor, blood pressure measuring equipment, enteral feeding equipment, solution and other supplies for renal dialysis and beds for patient were necessary in that order. In conclusion, the results of this study investigating special treatments and medical instruments and equipments used for home care patients and analyzing patients' need, were expected to be useful for expansion of application of long-term care insurance for the elderly and health insurance as well as for quality control of home care and development of medial instruments and equipments used at home.

• 대한의료기공학회지
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• 제17권1호
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• pp.83-108
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• 2017

Objects : The purpose of this study was to investigate Urinary Incontinence improvement effect of Moosim Gi-Gong Riding stance and to propose urinary incontinence treatment Program. Methods : We analyzed the effect of Moosim Gi-Gong Riding stance, and compared to Behavior theraphy which includes Kegel Exercise, Riding Stance of Ki-chum, Zhan-Zhuang-Gong. Results : 1. Moosim Gi-Gong Riding stance can correct the pelvic strain with principles such as horseback riding and help restore organs in the abdominal cavity. 2. Moosim Gi-Gong Riding stance can restore the ability to recover bladder and proximal urethra in right place through changes in the abdominal pressure by breathing and posture 3. Moosim Gi-Gong Riding stance can help restoring the ability to control the urination by increasing the intensity of the abdominal pressure and reinforcing Kidney, Liver, Spleen Meridian muscles. 4. Reinforcing Kidney, Liver, Spleen Meridian muscles can help to treat urinary incontinence through strengthening the tension between organs and activating the intestinal tract. Conclusions : This study shows that treatment program for Urinary Incontinence using Moosim Gi-Gong Riding stance can be useful to patient.

• 대한간호학회지
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• 제29권1호
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• pp.34-47
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• 1999

This study evaluated the Comparison of the Effectiveness of Pelvic Floor Muscle exercise and Biofeedback treatment for Genuine Stress Incontinence I assigned 60 participants to 2 groups : 30 to the pelvic floor muscle exercise group and 30 to the biofeedback group. Treatment protocol lasted for 6 weeks. Peak pressure, and duration time of pelvic muscle contraction were evaluated by a perineometer. Lower urinary symptoms, sexual matter and life style scores were achieved by using Jackson's scale. The treatment efficacy of the pelvic floor muscle exercise is compared with the biofeedback group and the main results of the comparison are as follows : 1. Pelvic muscle contraction 1) The peak pressure in the biofeedback group was significantly increased(P＝0.000). 2. The frequency and quantity of incontinence 1) The frequency of incontinence in the biofeedback group was significantly decreased(P＝0.000). 2) The quantity of incontinence in the biofeedback group was significantly decreased(P＝0.000). 3. The lower urinary symptoms Daily frequency(P＝0.000), nocturia(P＝0.000), urgency(P＝0.000), bladder pain(P＝0.000), unexplained incontinence(P＝0.048), wearing protection(P＝0.022), changing outer clothing(P＝0.005), hesitancy(P＝0.008), intermittent stream(P＝0.000), abnormal strength of stream(P＝0.004), retention(P＝0.000), incomplete emptying(P＝0.000), and inability to stop mid stream(P＝0.006) of the lower urinary symptoms in the biofeedbatk group were significantly decreased. 4. The sexual matters The dry vagina (P＝0.004) and pain during sexual Intercourse (P＝0.002) in the biofeedback group was significantly decreased. 5. The life style The fluid intake restriction(P＝0.007), affected daily task(P＝0.003), avoidance of places & situation(P＝0.003), interference in Physical activity (P＝0.002), interference in relationship with other people(P＝0.01), and feeling about the rest of life with urinary symptom(P＝0.000) in the biofeedback group were significantly decreased. In conclusion, the biofeedback treatment was more effective than the pelvic floor muscle exercise in genuine stress incontinence.

• 대한디지털의료영상학회논문지
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• 제16권2호
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• pp.15-24
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• 2014

Currently commercially available phantom can reproduce and evaluate only a static situation, the study is incomplete research on phantom and system which is can confirmed functional situation in the kidney by time through dynamic phantom and blood flow velocity, various difference according to the amount of radioactive. Therefore, through this study, it has produced the dynamic kidney phantom to reproduce images through the dynamic flow of the kidney, it desires to evaluate the usefulness of nuclear medicine imaging. The production of the kidney phantom was fabricated based on the normal adult kidney, in order to reproduce the dynamic situation based on the fabricated kidney phantom, in this study it was applied the volume pump that can adjust the speed of blood flow, so it can be integrated continuously radioactive isotopes in the kidney by using 99mTc-pertechnate. Used the radioactive isotope was supplied through the two pump. It was confirmed the changes according to the infusion rate, radioactive isotopes and the different injection speeds on the left and right, analysis of the acquired images was done by drawn five times ROI in order to check the reproducibility of each on the front and rear of the kidney and bladder. Depending on the speed of injection, radioisotope was a lot of integrated and emissions up when adjusting the pressure of the pump as 30 stroke, it was the least integrated and emissions up when adjusting as 40 stroke. The integration of the left & right kidney was not reached in the amount of the highest when adjusting as 10 stroke. In the changes according to the amount of the radioactive isotope, 0.6 mCi(22.2 MBq), 0.8 mCi (29.6 MBq)was showed up similar tendency but, in the result of the injection 0.8 mCi, it was showed up counts close to double of 0.6 mCi. In the result of the differently injection speed of the left & right kidney, as a result of different conditions that injection speed was 20 stroke through left kidney phantom, the injection speed was 30 stroke through right kidney phantom, it was enough difference in the resulting image can be easily distinguished with the naked eye. Through this study, the results showed that the dynamic kidney phantom system is able to similarly reproduce renogram in the actual clinical. Especially, the depicted over time for the flow to be excreted through the kidney into the bladder was adequately reproduce, it is expected to be utilized as basic data to check the quality of the dynamic images. In addition, it is considered to help in the field of functional imaging and quality control.

• 한국전문물리치료학회지
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• 제26권3호
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• pp.67-75
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• 2019

Background: Stress urinary incontinence (SUI) is an involuntary leakage of urine from the urethra when intra-abdominal pressure increases, such as from sneezing, coughing, or physical exertion. It is caused by insufficient strength of the pelvic floor and sphincter muscles, resulting from vaginal delivery, obesity, hard physical work, or aging. The pelvic floor electrical stimulator is a conservative treatment generally used to relieve the symptoms of urinary incontinence. it recommended to applied before surgery is performed. Objects: The purpose of this study was to determine if the transcutaneous electrical stimulation (TCES) would be effective for the physiological symptoms and psychological satisfaction of women with SUI for an 8-weeks intervention. Methods: Easy-K is a specially designed user-friendly TCES. Five female who were diagnosed with SUI by a gynecologist but who did not require surgical intervention were included in this study. Intervention was implemented over an 8-week period. Outcome measures included vaginal ultrasonography, Levator ani muscle (LAM) contraction strength, incontinence quality of life (I-QOL), and female sexual function index (FSFI) questionnaires. Results: The bladder neck position significantly decreased across assessment time. Funneling index and urethral width significantly decreased after 8 weeks of intervention (p<.05). The bladder necksymphyseal distance and posterior rhabdosphincter thickness statistically increased and the anterior rhabdosphincter thickness showed a tendency to increase. All participants demonstrated a significant increase in the LAM contraction score across three assessment times (p<.05). Although the total score of the I-QOL did not show significant improvement, it steadily increased and among I-QOL subscales, only the "avoidance" subscale showed statistical improvements (p<.05). The total score of the FSFI statistically improved and the "desire" score significantly changed (p<.05). Conclusion: The TCES is recommended for women who want to apply conservative treatments before surgery and who have suffered from SUI in aspects of sexual function and quality of life.

• 핵의학기술
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• 제17권2호
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• pp.3-9
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• 2013

핵의학 검사 중 동적 신장검사는 신장기능을 평가하는 가장 대표적인 검사법으로 방사성동위원소를 이용하여 시간에 따른 신장의 기능을 평가하고 소변이 배설에 이르기까지의 질환 평가에 유용하다. 이러한 검사영상의 질 평가 및 정량 분석에서 현재 상용화 된 팬텀은 정적 상황만 재현하고 평가할 수 있기 때문에 동적 팬텀을 통한 시간에 따른 신장의 기능적 상황과 혈류속도, 방사성동위원소의 주입량에 따른 다양한 차이 등을 확인할 수 있는 연구가 미비한 상황이다. 그러므로 본 연구를 통해 동적 신장팬텀 시스템을 제작하여 신장의 동적 흐름을 통한 영상을 재현함으로써 핵의학에서 영상학적으로 유용성을 평가하고자 한다. 신장팬텀은 정상 성인 신장을 기준으로 제작하였고, 동적 상황을 재현하기 위하여 혈류의 속도를 조절할 수 있는 정량 펌프를 적용하였으며, $^{99m}Tc-pertechnate$를 신장팬텀에 방사성의약품이 집적되고 방광으로 배설되도록 제작하였다. 사용된 방사성의약품은 각 신장팬텀에 각각 주입되도록 하였으며, 주입속도, 방사성의약품, 좌우 신장팬텀에 다른 주입속도에 따른 변화를 확인하였다. 획득한 영상의 분석은 전면상과 후면상 각각의 신장과 방광에 관심영역을 그려 분석하였으며, 재현성을 확인하기 위하여 각 10회씩 반복하여 분석하였다. 동일한 조건하에 주입속도 40 mL/min로 고정하여 펌프의 압력을 조절하였을 때 방사성의약품이 2-3분 사이에 신장팬텀에 가장 많이 집적되었다가 방광으로 배출되었다. 각 장비별 사구체 여과율은 각각 SYMBIA 1,091 mL/min, FORTE 1,232 mL/min, ARGUS 1,264 mL/min, INFINIA 1,302 mL/min로 통계적으로 유의한 차이가 있는 것으로 나타났으며, Tmax 값 그리고 T1/2 값 모두에서 장비별 통계적으로 유의한 차이가 있는 것으로 나타났다. 변동계수인 CV 값은 5% 이하로 재현성이 있는 것으로 나타났으며, 그 중에서 SYMBIA가 2.67%로 가장 낮게 나타났고, INFINIA가 4.86%으로 가장 높게 나타났다. 본 연구를 통하여 동적신장팬텀시스템이 실제 임상의 신장동적검사를 유사하게 재현이 가능한 것을 확인할 수 있었다. 특히 신장을 통해 방광으로 배설되는 흐름에 대해 시간에 따른 묘사가 충분하게 재현되었으며, 동적 영상의 질을 확인하는데 기초 자료로 활용이 가능하리라 사료된다. 또한 추후 기능적 영상 분야에 연구 및 정도관리 분야에도 도움이 되리라 여겨진다.