• Title/Summary/Keyword: Biopsy, Fine-needle

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Fine Needle Aspiration Cytology of Amyloid Goiter - A Case Report - (아밀로이드 갑상선종대의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Chae, Seoung-Wan;Nam, Eun-Sook;Kim, Duck-Hwan;Shin, Hyung-Sik;Sohn, Jin-Hee
    • The Korean Journal of Cytopathology
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    • v.11 no.2
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    • pp.109-114
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    • 2000
  • Amyloid golfer is a rare disease entity that is defined as a symptomatic mass or clinically detectable thyroid enlargement because of amyloid deposition. We present a case of amyloid golfer diagnosed in the fine needle aspiration cytology(FNAC) in a 73-year-old Korean woman presented with nephrotic syndrome and thyroid enlargement. The thyroid function was in normal range. Thyroid scan showed a nodule, $4{\time}2cm$ in the right lobe with underlying diffuse golfer. Aspirates revealed benign looking follicular cells and scattered eosinophilic material. The sections of the cell block showed nodular deposit of eosinophilic hyalinized material in the interfollicular area. It showed apple-green birefringence under polarization with Congo red stain. The renal biopsy also exhibited deposition of eosinophilic materials in the glomeruli and interstitial vascular wall, which were confirmed as amyloidosis. This material was morphologically distinct from the colloid.

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Percutaneous Fine Needle Aspiration Cytology of Malignancies of the Pancreas (췌장암의 경피성 세침 흡인 세포학적 검색)

  • Lee, Jung-Dal;Lyu, Keun-Shin;Ko, Jin-Seok;Lee, Chul-Yong
    • The Korean Journal of Cytopathology
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    • v.3 no.2
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    • pp.37-51
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    • 1992
  • The fine needle aspiration (FNA) cytology findings in 19 cases of primary neoplasia of the pancreas are reported. The aspirates were obtained under ultrasound guidance in 16 cases and under direct vision intraoperatively in three cases. These cases represented 79% of 24 diagnoses in a series of 30 pancreatic FNAs. Of these 30 cases no cytologic diagnoses were made in six cases (20%) because of insufficient or inadequate samples The cytologic diagnoses were confirmed by histologic examination following resection or biopsy of the tumors. The diagnoses included 9 duct ceil adenocarcinomas, 1 mucinous adenocarcinoma, 2 mucinous cystadenocarcinomas, 1 acinar cell carcinoma, 1 papillary cystic tumor 3 islet ceil tumors, 1 neuroendocrine carcinoma and 1 leiomyosarcoma. The cytologic features of the neoplasia were detailed and the differential diagnosis was discussed. The important criteria for the cytodiagnosis of pancreatic tumors were reviewed. This review leads us to think that nonoperative (percutaneous) cytologic approaches to the diagnosis of pancreatic tumor are advantageous for the management of patients, and that correct cytologic diagnosis with pancreatic FNAs can easily be made, if adequate samples are obtained.

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Fine Needle Aspiration Cytology of Pilomatrixoma - A Report of Five Cases - (모기질종의 세침흡인 세포학적 소견 - 5예 보고 -)

  • Park, Ho-Sung;Kang, Myoung-Jae;Lee, Dong-Geun;Chung, Myoung-Ja
    • The Korean Journal of Cytopathology
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    • v.11 no.1
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    • pp.53-58
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    • 2000
  • Pilomatrixoma is a benign tumor which usually occur as a solitary, firm nodule in the head and neck, and upper extremities of young people. This tumor is occasionally encountered during aspiration biopsy of subcutaneous masses, but only a small number of cases are correctly diagnosed prior to excision. We report five cases of pilomatrixoma. Four cases occurred in the neck and one case in the back. The characteristic fine needle aspiration cytologic features are shadow cells and basaloid cells in the background of inflammatory cells, including some multinucleated giant cells. The shadow cells were recognized in all five cases. These cells were pale, anucleated cells with relatively distinct cell borders. $May-Gr\ddot{u}nbald-Giemsa$ stain is useful for the identification of shadow cells. The recognition of shadow cells appears to be essential for accurate diagnosis of pilomatrixoma.

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Submandibular Soft Tissue Actinomycosis Diagnosed by Fine Needle Aspiration Cytology - A Case Report - (세침흡인 세포검사로 진단된 턱밑 연조직 방선균증 - 1예 보고 -)

  • Lee, Ho-Jung;Kim, Dong-Hoon;Lee, Won-Mi;Kim, Eun-Kyung;Joo, Jong-Eun
    • The Korean Journal of Cytopathology
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    • v.16 no.1
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    • pp.57-60
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    • 2005
  • A patient with actinomyces infection of the submandibular soft tissue was diagnosed by fine needle aspiration cytology (FNAC). A 38-year-old woman presented with a right submandibular mass which slowly grew in size over one month. Clinically and radiologically, the lesion was considered as tuberculous lymphadenitis or cellulitis. The polymerase chain reaction for tuberculosis was done by aspirated specimen but the result was negative. The smears of aspiration cytology showed characteristic colonies (sulfur granules) of actinomyces in inflammatory background. After antibiotic therapy for eight months, the patient has been well, showing no detectable mass. This patient was simply and rapidly diagnosed by FNAC and can avoid unnecessary surgical biopsy.

Percutaneous Fine Needle Aspiration Cytology of Adrenal Cortical Carcinoma - A Case Report - (부신피질암종의 세침흡인 세포학적 검색 - 1례 보고 -)

  • Jeong, Myoung-Ja;Lee, Ho;Kang, Myoung-Jae;Lee, Dong-Geun;Choi, Ho-Yeul;Kim, Sang-Ho
    • The Korean Journal of Cytopathology
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    • v.6 no.1
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    • pp.58-61
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    • 1995
  • Fine-needle aspiration (FNA) biopsy has become the procedure of choice for initial diagnosis of adrenal masses. However, there have been relatively few reports discussing the FNA cytologic features of adrenal cortical carcinoma. Recently, we experienced a case of FNA cytology of bilateral adrenal cortical carcinoma in a 61-year old man. The smear revealed loosely cohesive pleomorphic tumor cells with hemorrhagic and necrotic background. The tumor cells showed oval to spindle hyperchromatic nuclei and prominent nucleoli with frequent mitotic figures. The cytoplasm of tumor cells was relatively abundant and sometimes vacuolated. These cytologic findings were interpreted as an ad renal cortical carcinoma, undifferentiated pattern.

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Adenoid Cystic Carcinoma of the Breast: Diagnosis by Fine Needle Aspiration Cytology (유방의 선양 낭포성 암종 -세침흡인 세포검사로 진단된 1 예 보고-)

  • Lee, Dong-Wha;Jin, So-Young;Kim, Dae-Joong;Kwon, Kui-Hyang
    • The Korean Journal of Cytopathology
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    • v.2 no.2
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    • pp.160-167
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    • 1991
  • Adenoid cystic carcinoma is a rare valiant of mammary cancer with better prognosis. The diagnosis is usually made by histologic examination of biopsy specimen. Recently, we have experienced a case of adenoid cystlc carcinoma initially diagnosed by fine needle aspiration cytology which revealed distinct cytologic features in a 45-year-old woman. Pink to red globules in the tumor cell clusters on Diff-Quik staining was a very helpful finding for cytologic diagnosis.

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Fine Needle Aspiration Cytology of Subacute Necrotizing Lymphadenitis - Three Cases Report - (아급성 괴사성 림프절염 - 세침흡인 세포검사로 진단된 3예 보고 -)

  • Cho, Soo-Yeon;Cho, Min-Sun;Kim, Sung-Sook;Koo, Hye-Soo;Han, Woon-Sub;Chung, Sung-Min
    • The Korean Journal of Cytopathology
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    • v.5 no.1
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    • pp.23-27
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    • 1994
  • Three cases of subacute necrotizing lymphadenitis diagnosed by fine needle aspiration (FNA) of enlarged lymph nodes are reported. The FNA smears contained randomly activated lymphoid cells, necrotic debris and histiocytes. The same patterns were found in subsequently examined excised lymph nodes from these cases. The differential diagnosis of this entity is discussed and the value of preparing FNA cell blocks and accompanying AFB stain with culture is emphasized. FNA may be able to provide a diagnosis in case of this benign disease, therefore avoiding a more traumatic excisional biopsy.

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Fine Needle Aspiration Cytologic Features of Follicular Lymphoma (여포성 림프종의 세침흡인 세포학적 소견)

  • Chung, Jin-Haeug;Ha, Hwa-Jeong;Park, Sun-Hoo;Koh, Jae-Soo;Kim, Min-Suk;Lee, Seung-Sook;Cho, Kyung-Ja
    • The Korean Journal of Cytopathology
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    • v.13 no.2
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    • pp.60-65
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    • 2002
  • The accuracy of fine needle aspiration cytology (FNAC) for the diagnosis of follicular lymphoma was investigated by a review of 13 FNAC specimens from 10 patients. All patients Included in this study were confirmed by surgical biopsy preceded by FNAC. Three aspirates were unsatisfactory because of scanty cellularity. Among the remaining 10 cases, 5(50%) were diagnosed as lymphoma, 3(30%) as reactive hyperplasia, one (10%) as metastatic small cell carcinoma, and one (10%) as granulomatous inflammation. Cytologic distinction between follicular lymphoma and reactive hyperplasia is very difficult with cytomorphology alone. Compared to reactive hyperplasia, the characteristic cytologic features such as relatively homogeneous cellular constituent, paucity of tingible body macrophages and lymphohistiocytic aggregates, and less mitotic activity in follicular lymphoma are important findings to prevent false negative diagnosis. In addition, lymphoglandular bodies are useful in distinguishing malignant epithelial tumor from lymphoid lesion.

Fine Needle Aspiration Cytologic Findings of Kikuchi's Lymphadenitis - Analysis of 30 cases - (KIKUCHI 림프절염의 세침흡인 세포학적 소견 - 30예의 분석검토 -)

  • Yoo, Hyun-Ju;Cho, Hye-Je;Ko, Ill-Hyang
    • The Korean Journal of Cytopathology
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    • v.5 no.2
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    • pp.113-119
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    • 1994
  • Thirty cases of Kikuchi's lymphadenitis, diagnosed by fine needle aspiration cytology, were reviewed to determine the main cytologic features helpful in reaching a diagnosis. The patients(mean age 26.6 years, male: female = 1:3.8) presented with lymphadenopathy (cervical 24, submandibular 3, and axillary 1) with or without fever and local tenderness. Excisional biopsy was done for confirmation in 5 cases and the remaining 25 cases showed the similar cytologic and clinical features. In the aspiration smears of all cases, there was a heterogenous celluar mixture including frequent extracellular karyorrhectic nuclear debris, phagocytic histiocytes, plasmacytoid monocytes, and a variable number of polymorphous lymphocytes such as immunoblasts, activated large lymphocytes, and small mature lymphocytes. The characteristic cytologic features of Kikuchi's lymphadenitis were the following: (1) frequent extracelluar karyorrhectic nuclear debris in the background : (2) phagocytic histiocytes with eccentrically placed crescentic nuclei and abundant pale cytoplasm containing phagocytized karyorrhectic debris : (3) plasmacytoid monocytes, which were medium-sized cells with eccentrically placed round nuclei and amphophilic cytoplasm : (4) no neutrophilic background.

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Touch Imprint and Fine Needle Aspiration Cytology of Giant Cell Tumor of Tendon Sheath - A Case Report - (건초거대세포종의 압착도말 및 세포흡인 세포소견 - 1예 보고 -)

  • Lee, Jong-Im
    • The Korean Journal of Cytopathology
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    • v.19 no.1
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    • pp.57-64
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    • 2008
  • Giant cell tumor of the tendon sheath (GCTTS) is a slowly growing, benign soft tissue tumor. The tumors occur predominantly on the hands and feet. Although the clinical and histopathologic features are well-defined, only a few reports have described the cytologic appearance of this entity. A 26-year-old woman presented with a gradually developing circumscribed soft tissue mass near the proximal phalanx of her left little finger for one year. Imprint and fine needle aspiration (FNA) smears were obtained from the excisional biopsy specimen. The imprint smears were composed of predominantly singly dispersed bland mononuclear cells and several giant cells. The mononuclear cells were polygonal to round, and they showed a histiocyte-like appearance. Osteoclast-type multinucleated giant cells of various sizes were randomly scattered throughout the smears, and these cells contained 3 to 50 nuclei. Nuclear atypia and pleomorphism were absent in both the single and giant cells. Loose aggregates of hemosiderin-laden macrophages and binuclear stromal cells were also seen. The cytologic features of the FNA smears were similar with those of the imprint, Additionally, the FNA smears contained several clumps of densely collagenous stromal tissue that were seldom noted in previously reported cytologic material. The cytologic features were well-correlated with the concurrent histologic findings and the diagnosis of GCTTS was made. When the clinical and radiologic datas are integrated, the diagnosis of GCTTS can be strongly suggested, based on the pre-operative cytologic specimen.