• 대한기계학회:학술대회논문집
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• 대한기계학회 2005년도 창립60주년 기념 추계 학술대회
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• pp.151.2-151.2
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• 2005

• 한국가시화정보학회지
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• 제16권1호
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• pp.15-20
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• 2018

For the measurement of biophysical properties related with cardiovascular diseases (CVD), various microfluidic devices were proposed. However, many devices were monitored by optical equipment. Ultrasound measurement to quantify the biophysical properties can provide new insights to understand the cardiovascular diseases. This study aims to check feasibility of microfluidic device for ultrasound image analysis based on 3D printer. To facilitate acoustic transmission, agarose solution is poured around 3D mold connected with holes of the acrylic box. By applying speckle image velocimetry(SIV) technique, flow information in the bifurcated channel was estimated. Considering that ultrasound signal amplitude is determined by red blood cell (RBC) aggregation, RBC aggregation in the bifurcated channel can be estimated through the analysis of ultrasound signal. As examples of microfluidic device which mimic the CVD model, velocity fields in microfluidic devices with stenosis and aneurysm were introduced.

• 한국생물물리학회:학술대회논문집
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• 한국생물물리학회 2002년도 제9회 학술 발표회 프로그램과 논문초록
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• pp.45-45
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• 2002

Extracellular ATP regulates a wide range of cellular function including the growth of prostate gland. Purinoceptors (ATP receptors) are divided into P2X (ligand-gated ion channels) and P2Y (G-protein-coupled receptor) subfamilies. In the present study, we investigated the types of purinoceptors in rat prostate neuroendocrine (RPNE) cells using whole-cell patch clamp technique, intracellular $Ca^{2+}$ measurement and RT-PCR analysis.(omitted)d)

• 대한의용생체공학회:의공학회지
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• 제28권2호
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• pp.169-173
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• 2007

During laser irradiation, mechanically deformed cartilage undergoes a temperature dependent phase transformation resulting in accelerated stress relaxation. Clinically, laser-assisted cartilage reshaping may be used to recreate the underlying cartilaginous framework in structures such as ear, larynx, trachea, and nose. Therefore, research and identification of the biophysical transformations in cartilage accompanying laser heating are valuable to identify critical laser dosimetry and phase transformation of cartilage for many clinical applications. quasi-elastic light scattering was investigated using Ho : YAG laser $(\lambda=2.12{\mu}m\;;\;t_p\sim450{\mu}s)$ and Nd:YAG Laser $(\lambda=1.32{\mu}m\;;\;t_p\sim700{\mu}s)$ for heating sources and He : Ne $(\lambda=632.8nm)$ laser, high-power diode pumped laser $(\lambda=532nm)$, and Ti : $Al_2O_3$ femtosecond laser $(\lambda=850nm)$ for light scattering sources. A spectrometer and infrared radiometric sensor were used to monitor the backscattered light spectrum and transient temperature changes from cartilage following laser irradiation. Analysis of the optical, thermal, and quasi-elastic light scattering properties may indicate internal dynamics of proteoglycan movement within the cartilage framework during laser irradiation.

• 대한화장품학회지
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• 제41권4호
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• pp.413-420
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• 2015

피부는 신체에서 가장 크고 육중한 기관 중 하나로 인간의 생리 및 병리 과정에 참여한다. 피부는 자기 유지 및 치유, 기계적 및 화학적 손상 방어, 자외선 과 외부 병원성 미생물로부터의 방어, 비타민 D 합성 그리고 사회 심리적 기능을 한다고 알려져 있다. 이 연구의 목적은 한국 여성의 부위와 연령에 따라 피부 생물학 인자와 연관된 생물리학 인자의 변화를 평가하는 데 있다. 20 ~ 49세의 약 70명의 건강한 성인 여성이 이 실험에 참여하였다. 측정부위는 하박 내측과 뺨으로 진행하였다. 인체 피부의 생물리학 인자를 측정하기 위하여 여러 가지 비침습적인 방법으로 진행하였다. 피부의 생물학 인자를 분석하기 위하여 코티졸, 파이브로넥틴, 케라틴-1, 10, 11, 인보루크린, 케라틴 6를 인체의 얼굴과 하박내측으로 비교하였다. 또한 비침습적 방법으로 피부 생물리학 인자는 피부 부위와 연령에 따른 차이를 측정하였다. 측정 부위에 따른 결과, 각질층 수분량, 경피수분손실량과 피부색(L과 a값)은 유의적인 차이가 나타났다. 연령에 따른 결과, 오직 피부색에서만 연령에 따른 차이가 유의적으로 나타났다. 코티졸, 케라틴-6, 파이브로넥틴, 케라틴-1, 10, 11 은 연령과 부위간 유의적 차이가 없지만 인볼루크린은 30 ~ 39세 연령대에서 다른 연령대보다 유의적으로 가장 높았다. 이러한 결과는 개인의 피부 환경에 대한 상세한 피부 상태 변화로 설명할 수 있을 것이다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2003년도 춘계학술대회 논문집
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• pp.237-240
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• 2003

In biological cell manipulation, manual thrust or penetration of an injection pipette into an embryo cell is currently performed by a skilled operator, relying on visual feedback information only. Accurately measuring cellular forces is a requirement for minimally invasive cell injections. Moreover, the cellular farce sensing is essential in investigating the biophysical properties for cell injury and membrane modeling studies. This paper presents cellular force measurements for the force feedback-based biomanipulation. Cellular force measurement system using piezoelectric polymer sensor is implemented to measure the penetration force of a zebrafish egg cell. First, measurement system setup and calibration are described. Second, the force feedback-based biomanipulation is experimentally carried out. Experimental results show that it successfully supplies real-time cellular force feedback to the operator at several tens of uN and thus plays a main role in improving the reliability of biological cell injection tasks.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2006년도 Proceedings of ISRS 2006 PORSEC Volume I
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• pp.402-405
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• 2006

Radiometric calibration of optical image data is necessary to convert raw digital number (DN) value of each pixel into a physically meaningful measurement (radiance). To extract rather quantitative information regarding biophysical characteristics of the earth surface materials, radiometric calibration is often essential procedure. A sensor detects the radiation of sunlight interacted atmospheric constituents. Therefore, the amount of the energy reaching at the sensor is quite different from the initial amount reflected from the surface. To achieve the target reflectance after atmospheric correct, an initial step is to convert DN value to at-sensor radiance. A linear model, the simplest radiometric model, is applied to averaged spectral radiance for this conversion. This study purposes to analyze the sensitivity of several factors affecting on radiance for carrying out absolute radiometric calibration of panchromatic images from KOMPSAT2 launched at July, 2006. MODTRAN is used to calculate radiance at sensor and reflectance of target is measured by a portable spectro-radiometer at the same time the satellite is passing the target for the radiometric calibration. As using different contents of materials composing of atmosphere, the differences of radiance are investigated. Because the spectral sensitivity of panchromatic images of KOMPSAT2 ranges from 500 to 900 nm, the materials causing scattering in visible range are mainly considered to analyze the sensitivity. According to the verified sensitivity, direct measurement can be recommenced for absolute radiometric calibration.

• 대한기계학회논문집A
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• 제27권12호
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• pp.2079-2084
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• 2003

In biological cell manipulation, manual thrust or penetration of an injection pipette into an embryo cell is currently performed by a skilled operator, relying on visual feedback information only. Accurately measuring cellular forces is a requirement for minimally invasive cell injections. Moreover, the cellular force sensing is essential in investigating the biophysical properties for cell injury and membrane modeling studies. This paper presents cellular force measurements for the force feedback-based biomanipulation. Cellular force measurement system using piezoelectric polymer sensor is implemented to measure the penetration force of a zebrafish egg cell. First, measurement system setup and calibration are described. Second, the force feedback-based biomanipulation is experimentally carried out. Experimental results show that it successfully supplies real-time cellular force feedback to the operator at tens of uN and thus plays a main role in improving the reliability of biological cell injection tasks.

• 한국농림기상학회지
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• 제11권3호
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• pp.118-122
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• 2009

Net Radiation ($R_N$) is the major driving force for biophysical and biogeochemical processes in the terrestrial ecosystems, which is one of the most critical variables in both measurement and modeling. Despite its importance, there are only 10 weather stations conducting $R_N$ measurements among the 544 stations operated by Korea Meteorological Administration (KMA; KMA, 2008). The measurement of incoming shortwave radiation ($R_S{\downarrow}$) is, however, conducted at 22 stations while that of sunshine duration is conducted at all the manned stations. In this context, the recent research for estimating $R_N$ using $R_S{\downarrow}$ in Korean peninsula by Kwon (2009) is of great worth. The author used a linear regression and the radiation balance methods. We generally agree with the author that, in terms of simplicity and practicality, both methods show reliable applicability for estimating $R_N$. We noted, however, that the author's experimental method and analysis need some clarification and improvement, that are addressed in the following perspectives: (1) the use of daily integrated data for regression, (2) the use of measured albedo, (3) the use of linear coefficients for whole year data, (4) methodological improvement, (5) the use of sunshine duration, and (6) the error assessment.

• 한국측량학회지
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• 제33권6호
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• pp.547-555
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• 2015

The vegetation index is a crucial parameter in many biophysical studies of vegetation, and is also a valuable content in ecological processes researching. The OVIs (Optical Vegetation Index) that of using multispectral and hyperspectral data have been widely investigated in the literature, while the RVI (Radar Vegetation Index) that of considering volume scattering measurement has been paid relatively little attention. Also, there was only some efforts have been put to fuse the OVI with the RVI as an integrated vegetation index. To address this issue, this paper presents a novel FVI (Fusion Vegetation Index) that uses multispectral and full-PolSAR (Polarimetric Synthetic Aperture Radar) data. By fusing a NDVI (Normalized Difference Vegetation Index) of RapidEye and an RVI of C-band Radarsat-2, we demonstrated that the proposed FVI has higher separability in different vegetation types than only with OVI and RVI. Also, the experimental results show that the proposed index not only has information on the vegetation greenness of the NDVI, but also has information on the canopy structure of the RVI. Based on this preliminary result, since the vegetation monitoring is more detailed, it could be possible in various application fields; this synergistic FVI will be further developed in the future.