• Journal of Biomedical Engineering Research
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• v.11 no.1
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• pp.131-140
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• 1990

To improve antithrombogenicity of polymer that used in vascular graft and artificial organs, seeding of human endothelial cells on the polyurethane was studied. Human endothelial cells were ismlated from human umbilical veins, using type I collagenase, and identified with goat anti vWF antibodies. Human endothilial cell seeding was tried upon the polyurethane which has good mechanical property and resists stresses. The hydrophobic polyurethane surface was changed hydrophilic by corona discharf:e treatment. Surface hydrophilicity was measured with Wilhemly plate method and the goniometer. To evaluate matrix protein adsorption, fibronectin adsorption test was done. To eveluate cell adhesion, human endothelial cell attachment forces were measured rising a perfusion chamber of , ism diamter. Less cells were detached from the hydrophilically treated polyurethane. This showed that corona discharge on the polyurethane could improve matrix adsorption and endothelial cell attachment.

• Proceedings of the KIEE Conference
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• 1996.07c
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• pp.1997-2000
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• 1996

A strip-type bending actuator using perfluoro sulfonic acid film ($Nafion^{(R)}$ 117, Du Pont), which is a kind of conducting polymer, fabricated and characterized. Conducting polymer is a useful material as an actuator due to the simple structure, fabrication method and low driving voltage. Experimental results show that the fabricated bending actuator has about ${\pm}10^{\circ}$ of bending angle at 4 V and fast response, which means that the conducting polymer can be used practically as actuator material.

• Proceedings of the KOSOMBE Conference
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• v.1991 no.11
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• pp.101-102
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• 1991

• Proceedings of the KOSOMBE Conference
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• v.1992 no.11
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• pp.115-116
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• 1992

• Proceedings of the KOSOMBE Conference
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• v.1993 no.05
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• pp.139-140
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• 1993

• Proceedings of the Korean Society of Sericultural Science Conference
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• 1997.06a
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• pp.159-169
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• 1997

ABA-type(or AB) block copolymers composed of poly(${\gamma}$-alkyl L-glutamate) (PALG)[or poly(L-leucine)] as the A component and polyether[or poly (N-isopropy1 acrylamide) as the B component were synthesized by polymerization of (${\gamma}$-alkyl L-glutamate N-carboxyanhydride initiated by primary amined located at both(or one) ends of the polymer chains. Structural studies of the block copolymers were performed in the solution and solid state. Also, artificial skin, drug delivery system of the block copolymers and cell attachment onto the copolymer were carried out for biomedical applications.

• Polymer Science and Technology
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• v.1 no.4
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• pp.205-210
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• 1990

• Polymer Science and Technology
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• v.5 no.6
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• pp.551-557
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• 1994

• Proceedings of the KOSOMBE Conference
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• v.1993 no.05
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• pp.105-106
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• 1993

• Applied Chemistry for Engineering
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• v.19 no.5
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• pp.457-465
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• 2008

Development of various medical systems was accomplished through the progress of biotechnological method for therapy of human diseases. Furthermore, drug delivery systems have been investigated to carry the bioactive materials such as drug or gene in the body effectively. The most important thing in this system is to develop biomedical polymers having biocompatibility, biodegradability, and non-toxicity. Chitosan, a natural polymer, has been importantly considered as biomedical materials due to its good biocompatibility and various bio-active characteristics. Since the property of chitosan is differently explained according to the crystalline structures of chitin, the study for structural analysis of chitin has to proceed to apply as a biomaterial. From this point of view, this article introduced the analysis of crystalline structural of chitin, general property of chitosan and potential characteristics of low molecular weight water-soluble chitosan (LMWSC) as a biomaterials. Furthermore, chemical modification of LMWSC using various functional groups was also performed to enhance its bioavailability and emphasize their potential as drug delivery carriers (DDS).