• Journal of the Institute of Convergence Signal Processing
• /
• v.21 no.4
• /
• pp.183-194
• /
• 2020

Recently, the number of hip dysplasia (DDH) that occurs during infant and child growth has been increasing. DDH should be detected and treated as early as possible because it hinders infant growth and causes many other side effects In this study, two modelling techniques were used for multiple training techniques. Based on the results after the first transformation, the training was designed to be possible even with a small amount of data. The vertical flip, rotation, width and height shift functions were used to improve the efficiency of the model. Adam optimization was applied for parameter learning with the learning parameter initially set at 2.0 x 10e-4. Training was stopped when the validation loss was at the minimum. respectively A novel image overlay system using 3D laser scanner and a non-rigid registration method is implemented and its accuracy is evaluated. By using the proposed system, we successfully related the preoperative images with an open organ in the operating room

• The Korean Journal of Nuclear Medicine
• /
• v.32 no.4
• /
• pp.332-343
• /
• 1998

Purpose: The purpose of this study was to assess the diagnostic accuracy of various quantitation methods using F-18-fluorodeoxyglucose (FDG) in patients with malignant or benign lung lesion. Materials and Methods: 22 patients (13 malignant including 5 bronchoalverolar cell cancer; 9 benign lesions including 1 hamartoma and 8 active inflammation) were studied after overnight fasting. We performed dynamic PET imaging for 56 min after injection of 370 MBq (10 mCi) of FDG. Standardized uptake values normalized to patient's body weight and plasma glucose concentration (SUVglu) were calculated. The uptake rate constant of FDG and glucose metabolic rate were quantified using Patlak graphical analysis (Kpat and MRpat), three compartment-five parameter model (K5p, MR5p), and six parameter model taking into account heterogeneity of tumor tissue (K6p, MR6p). Areas under receiver operating characteristic curves (ROC) were calculated for each method. Results: There was no significant difference of rate constant or glucose metabolic rate measured by various quantitation methods between malignant and benign lesions. The area under ROC curve were 0.73 for SUVglu, 0.66 for Kpat, 0.77 for MRpat, 0.71 for K5p, 0.73 for MR5p, 0.70 for K6p, and 0.78 for MR6p. No significant difference of area under the ROC curve between these methods was observed except the area between Kpat vs. MRpat (p<0.05). Conclusion: Quantitative methods did not improve diagnostic accuracy in comparison with nonkinetic methods. However, the clinical utility of these methods needs to be evaluated further in patients with low pretest likelihood of active inflammation or bronchoalveolar cell carcinoma.

• Journal of Korea Multimedia Society
• /
• v.23 no.8
• /
• pp.1040-1048
• /
• 2020

In this study, in order to improve the implantable bone conduction transducer of the prototype proposed by Shin et al., the effect of the element parameters of the transducer on the frequency characteristics was analyzed using electromagnetic and mechanical vibration analysis. Electromagnetic analysis was performed on the size of the permanent magnet and the distance between the metal plate and the coil to derive an optimal structure that generates the maximum Lorentz force. In addition, mechanical vibration analysis was performed on the cantilever structure of the vibrational membrane in order to minimize the distortion of the transducer and to have a frequency characteristic suitable for conductive hearing loss compensation. The frequency characteristics of the transducer of the optimal structure derived through finite element method were compared with the simulation results of the previous transducer. As a result, the output magnitude (displacement) of the transducer designed with the optimal structure generated an average 8.8 times higher than the previous transducer, and the resonance frequency was generated at 0.9 kHz.

• Proceedings of the KOSOMBE Conference
• /
• v.1997 no.05
• /
• pp.285-289
• /
• 1997

In this paper, we describe the intrabed and interbed network in a developed patient monitoring system. Intrabed network handles data communication among the main unit of a bedside monitor and parameter modules plugged in it. Interbed network deals with a higher level data communication among many bedside monitors, central stations, DB servers, and clinical workstations. Analyzing the data communication requirements in each stage of the system, we designed the intrabed network based upon RS-485 and HDLC protocol with 1Mbps data rate. Interbed network is designed to utilize the industry standard 10Base-T Ethernet with TCP/IP and UDP protocol. We present the specifications and the performances of the developed data communication networks in the patient monitoring system.

• 제어로봇시스템학회:학술대회논문집
• /
• 2005.06a
• /
• pp.202-205
• /
• 2005

The purpose of this work is to identify the characteristic of eye movement for visual training of the elderly. This investigation is to examine the relationship between the head and the eye motor system for the localization of visual target direction in three-dimensional space. All experiments were performed in a soundproof chamber. Twenty-one red LEDs (Light-Emitting Diode, Brightness: 20cd/$m^2$) arrayed in three lines on a half circle-surrounding panel are used. LEDs are horizontally 30 degree apart and vertically 20 degree apart from each other. The condition of stimulation is random and anti-saccade. Physiological parameter such as EOG (Electro-Oculography) was measured by BIOPAC system. We measure the mean latency time, which is the time from the start of visual stimulation to the response of the human body. The result shows that the mean latency time is short in the case of the condition of anti-saccade, the fixed head and a quarter visual stimulation. This finding can be used in developing programs for various visual improvements for the elderly by analyzing the characteristic of eye movement.

• Journal of Sensor Science and Technology
• /
• v.13 no.2
• /
• pp.79-84
• /
• 2004

Asthma is one of the important respiratory diseases requiring home self care usually performed by commercialized peak expiratory flow meter (PEFM). However, this simple device can measure only single parameter, PEF, due to its purely mechanical principle, significantly limiting desease management quality. The present study introduced a new expiratory flow measurement technique by miniatured air expansion chamber easily installed within PEFM. Continuous pressure signal obtained from the chamber demonstrated an accurate quadratic relationship with flow. The volume measurement error was $<{\pm}1%$ well within the American Thoracic Society (ATS) criteria of 3%. Important spirometric parameters of FVC, PEF, and FEF25-75% were all accurately estimated with correlation coefficients > 0.95. The present technique obtains continuous expiratory air flow signal, making possible and convenient to perform spirometric test at home. Electronic interface capability would be also useful for remote asthma management.

• Journal of Biomedical Engineering Research
• /
• v.31 no.4
• /
• pp.302-309
• /
• 2010

The present study proposed a method of measuring uroflow and urophonography at the same time for more accurate diagnosis in case uroflow looks normal due to compensatory function hypertrophy in the expression of early obstruction. In case of early obstruction, there happens turbulent uroflow by the obstruction even if the uroflow looks normal and thus obstruction can be detected by measuring and analyzing signal caused by turbulent flow. We implemented a system that can measure both uroflow and urophonography, and evaluated its performance. In the experiment, we observed changes in uroflow and urophonography according to artificial pressure and the degree of obstruction, and confirmed that it is possible to determine the effect of compensatory function hypertrophy by analyzing urophonographyic parameter under the same uroflow. The results of our experiment show that the effect of compensatory function hypertrophy in the early-stage obstruction of lower urinary tract, which is not detectible with uroflowmetry alone, can be assessed through urophonographic analysis.

• Journal of Biomedical Engineering Research
• /
• v.18 no.4
• /
• pp.413-420
• /
• 1997

In this paper, we analyzed the contraction patterns of active elbow muscles during isometric, concentric and eccentric contraction. The analysis parameters consist of frequency domain parameters (mean frequency, median frequency, peak frequency, peak power, skewness, kurtosis) and time domain paraseters (zero crossing, positive maxima, integrated EMG). The results of this study were as follows; The BR/BB of isometric contraction appeared to be Venter as the elbow joint was more extended. The BR /BB during concentric and eccentric contraction tended to increase with more extension of the elbow joint angle, but there was no significant difference between concentric and eccentric contraction. Further, the EMG power spectrum due to the type of contraction were different betwen eccentric and concentric contraction. According to the results, it was found that the activation pattern in elbow flexor muscles was different during three different muscle contraction pattern. Therefore, elbow flexor muscles should not be considered a single functioning unit. Especially, at the time domain analysis, IEMG is a dominant parameter for analysis of activation patterns, and the skewness kurtosis can be useful parameters in functional recognition for prosthesis control purpose.

• Journal of Biomedical Engineering Research
• /
• v.17 no.1
• /
• pp.25-32
• /
• 1996

A new analytic method has been developed for the analysis of sperm morphology using Hough transform. This method is based on the characteristic that sperm heads have elliptic shape in addition to the density difference with the background Sperm heads are represented in elliptic form with five parameter, and the optimal parameters are estimated by iterative Hough transform. To reduce processing time practically, we restricted the transformed space in minimum volume and moved the searching volume to the maximum gradient for the estimated error. Morphological parameters were calculated from estimated sperm head boundaries without further processing.

• The Korean Journal of Physiology and Pharmacology
• /
• v.20 no.4
• /
• pp.367-378
• /
• 2016

Recently, it was reported that the role of mitochondria-reactive oxygen species (ROS) generating pathway in cisplatin-induced apoptosis is remarkable. Since a variety of molecules are involved in the pathway, a comprehensive approach to delineate the biological interactions of the molecules is required. However, quantitative modeling of the mitochondria-ROS generating pathway based on experiment and systemic analysis using the model have not been attempted so far. Thus, we conducted experiments to measure the concentration changes of critical molecules associated with mitochondrial apoptosis in both human mesothelioma H2052 and their ${\rho}^0$ cells lacking mitochondrial DNA (mtDNA). Based on the experiments, a novel mathematical model that can represent the essential dynamics of the mitochondrial apoptotic pathway induced by cisplatin was developed. The kinetic parameter values of the mathematical model were estimated from the experimental data. Then, we have investigated the dynamical properties of this model and predicted the apoptosis levels for various concentrations of cisplatin beyond the range of experiments. From parametric perturbation analysis, we further found that apoptosis will reach its saturation level beyond a certain critical cisplatin concentration.