• Title/Summary/Keyword: Biomedical NER

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PharmacoNER Tagger: a deep learning-based tool for automatically finding chemicals and drugs in Spanish medical texts

  • Armengol-Estape, Jordi;Soares, Felipe;Marimon, Montserrat;Krallinger, Martin
    • Genomics & Informatics
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    • v.17 no.2
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    • pp.15.1-15.7
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    • 2019
  • Automatically detecting mentions of pharmaceutical drugs and chemical substances is key for the subsequent extraction of relations of chemicals with other biomedical entities such as genes, proteins, diseases, adverse reactions or symptoms. The identification of drug mentions is also a prior step for complex event types such as drug dosage recognition, duration of medical treatments or drug repurposing. Formally, this task is known as named entity recognition (NER), meaning automatically identifying mentions of predefined entities of interest in running text. In the domain of medical texts, for chemical entity recognition (CER), techniques based on hand-crafted rules and graph-based models can provide adequate performance. In the recent years, the field of natural language processing has mainly pivoted to deep learning and state-of-the-art results for most tasks involving natural language are usually obtained with artificial neural networks. Competitive resources for drug name recognition in English medical texts are already available and heavily used, while for other languages such as Spanish these tools, although clearly needed were missing. In this work, we adapt an existing neural NER system, NeuroNER, to the particular domain of Spanish clinical case texts, and extend the neural network to be able to take into account additional features apart from the plain text. NeuroNER can be considered a competitive baseline system for Spanish drug and CER promoted by the Spanish national plan for the advancement of language technologies (Plan TL).

Encoding Dictionary Feature for Deep Learning-based Named Entity Recognition

  • Ronran, Chirawan;Unankard, Sayan;Lee, Seungwoo
    • International Journal of Contents
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    • v.17 no.4
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    • pp.1-15
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    • 2021
  • Named entity recognition (NER) is a crucial task for NLP, which aims to extract information from texts. To build NER systems, deep learning (DL) models are learned with dictionary features by mapping each word in the dataset to dictionary features and generating a unique index. However, this technique might generate noisy labels, which pose significant challenges for the NER task. In this paper, we proposed DL-dictionary features, and evaluated them on two datasets, including the OntoNotes 5.0 dataset and our new infectious disease outbreak dataset named GFID. We used (1) a Bidirectional Long Short-Term Memory (BiLSTM) character and (2) pre-trained embedding to concatenate with (3) our proposed features, named the Convolutional Neural Network (CNN), BiLSTM, and self-attention dictionaries, respectively. The combined features (1-3) were fed through BiLSTM - Conditional Random Field (CRF) to predict named entity classes as outputs. We compared these outputs with other predictions of the BiLSTM character, pre-trained embedding, and dictionary features from previous research, which used the exact matching and partial matching dictionary technique. The findings showed that the model employing our dictionary features outperformed other models that used existing dictionary features. We also computed the F1 score with the GFID dataset to apply this technique to extract medical or healthcare information.

Improving classification of low-resource COVID-19 literature by using Named Entity Recognition

  • Lithgow-Serrano, Oscar;Cornelius, Joseph;Kanjirangat, Vani;Mendez-Cruz, Carlos-Francisco;Rinaldi, Fabio
    • Genomics & Informatics
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    • v.19 no.3
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    • pp.22.1-22.5
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    • 2021
  • Automatic document classification for highly interrelated classes is a demanding task that becomes more challenging when there is little labeled data for training. Such is the case of the coronavirus disease 2019 (COVID-19) clinical repository-a repository of classified and translated academic articles related to COVID-19 and relevant to the clinical practice-where a 3-way classification scheme is being applied to COVID-19 literature. During the 7th Biomedical Linked Annotation Hackathon (BLAH7) hackathon, we performed experiments to explore the use of named-entity-recognition (NER) to improve the classification. We processed the literature with OntoGene's Biomedical Entity Recogniser (OGER) and used the resulting identified Named Entities (NE) and their links to major biological databases as extra input features for the classifier. We compared the results with a baseline model without the OGER extracted features. In these proof-of-concept experiments, we observed a clear gain on COVID-19 literature classification. In particular, NE's origin was useful to classify document types and NE's type for clinical specialties. Due to the limitations of the small dataset, we can only conclude that our results suggests that NER would benefit this classification task. In order to accurately estimate this benefit, further experiments with a larger dataset would be needed.

Performance Comparison of Recurrent Neural Networks and Conditional Random Fields in Biomedical Named Entity Recognition (의생명 분야의 개체명 인식에서 순환형 신경망과 조건적 임의 필드의 성능 비교)

  • Jo, Byeong-Cheol;Kim, Yu-Seop
    • 한국어정보학회:학술대회논문집
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    • 2016.10a
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    • pp.321-323
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    • 2016
  • 최근 연구에서 기계학습 중 지도학습 방법으로 개체명 인식을 하고 있다. 그러나 지도 학습 방법은 데이터를 만드는 비용과 시간이 많이 필요로 한다. 본 연구에서는 주석 된 말뭉치를 사용하여 지도 학습 방법을 사용 한다. 의생명 개체명 인식은 Protein, RNA, DNA, Cell type, Cell line 등을 포함한 텍스트 처리에 중요한 기초 작업입니다. 그리고 의생명 지식 검색에서 가장 기본과 핵심 작업 중 하나이다. 본 연구에서는 순환형 신경망과 워드 임베딩을 자질로 사용한 조건적 임의 필드에 대한 성능을 비교한다. 조건적 임의 필드에 N_Gram만을 자질로 사용한 것을 기준점으로 설정 하였고, 기준점의 결과는 70.09% F1 Score이다. RNN의 jordan type은 60.75% F1 Score, elman type은 58.80% F1 Score의 성능을 보여준다. 조건적 임의 필드에 CCA, GLOVE, WORD2VEC을 사용 한 결과는 각각 72.73% F1 Score, 72.74% F1 Score, 72.82% F1 Score의 성능을 얻을 수 있다.

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Performance Comparison of Recurrent Neural Networks and Conditional Random Fields in Biomedical Named Entity Recognition (의생명 분야의 개체명 인식에서 순환형 신경망과 조건적 임의 필드의 성능 비교)

  • Jo, Byeong-Cheol;Kim, Yu-Seop
    • Annual Conference on Human and Language Technology
    • /
    • 2016.10a
    • /
    • pp.321-323
    • /
    • 2016
  • 최근 연구에서 기계학습 중 지도학습 방법으로 개체명 인식을 하고 있다. 그러나 지도 학습 방법은 데이터를 만드는 비용과 시간이 많이 필요로 한다. 본 연구에서는 주석 된 말뭉치를 사용하여 지도 학습 방법을 사용 한다. 의생명 개체명 인식은 Protein, RNA, DNA, Cell type, Cell line 등을 포함한 텍스트 처리에 중요한 기초 작업입니다. 그리고 의생명 지식 검색에서 가장 기본과 핵심 작업 중 하나이다. 본 연구에서는 순환형 신경망과 워드 임베딩을 자질로 사용한 조건적 임의 필드에 대한 성능을 비교한다. 조건적 임의 필드에 N_Gram만을 자질로 사용한 것을 기준점으로 설정 하였고, 기준점의 결과는 70.09% F1 Score이다. RNN의 jordan type은 60.75% F1 Score, elman type은 58.80% F1 Score의 성능을 보여준다. 조건적 임의 필드에 CCA, GLOVE, WORD2VEC을 사용 한 결과는 각각 72.73% F1 Score, 72.74% F1 Score, 72.82% F1 Score의 성능을 얻을 수 있다.

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