• 제목/요약/키워드: Biological systems

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편집자 주: 31권 2호 (Editorial for Vol. 31, No. 2)

  • 김영효
    • 항공우주의학회지
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    • 제31권2호
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    • pp.31-32
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    • 2021
  • In Vol. 31, No. 2, our journal prepared a review article, two original papers, and three case reports. First, autonomous systems are increasingly being introduced in aircraft systems. Therefore, it is crucial that flight crews are trained to adapt and handle these autonomous systems better. Consequently, we discussed crew resource management for handling autonomous systems. The fatigue of aviation workers is one of the biggest threats to aviation safety. Therefore, we analyzed the degree of fatigue in commercial aircraft pilots and evaluated the relationship between fatigue and their workload and the effect of fatigue on sleep. Since obesity has a significant impact on the health of aviation workers, we also comparatively analyzed the prevalence of obesity in Korea and Japan based on the data from the National Health and Nutrition Examination Survey. We defined cases that are difficult for aviation medical examiners to evaluate. This issue included cases of peripheral dizziness and tinnitus, cases of atopic dermatitis treated with biological agents, and cases of malignant tumors.

Frequency Responses of Ambulatory ECG Systems and Their Correction by a Compensation Circuit

  • Iwao, K.;Yokoi, A.;Suzuki, S.;Goto, T.;Doniwa, K.;Okajima, M.
    • 대한의용생체공학회:의공학회지
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    • 제11권1호
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    • pp.13-18
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    • 1990
  • Frequency responses of ambulatory electrocardiogram systems were measured. Phase shift was assessed by our improved Wagner's method. The characteristics of the systems were found much worse than that of ordinary ECG equipment both in gain and phase responses. The decay of -3dB in amplitude observed in 0.2Hz and the lead of 45 dog in phase was observed in 0.6Hz. In order to investigate which of these 2 responses play major role in generating false S -T deviation, mathe- matical filters were Composed in a computer and actual ECGs were fed. The false S-T deviation were found to be caused mostly by enormous lead in phase, and then, the compensation circuit to diminish the lead in phase was inserted in the commercial systemes. The compensated systems showed no false deviation in S-T segment.

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화학공정 산업에서의 지속가능성과 공정시스템 공학 (The Role of Process Systems Engineering for Sustainability in the Chemical Industries)

  • 장남진;단승규;신동일;이기백;윤인섭
    • Korean Chemical Engineering Research
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    • 제51권2호
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    • pp.221-225
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    • 2013
  • 지속가능성이란 사회적, 경제적, 환경적인 영향을 전반적으로 고려하며, 인간의 건강과 생활 증진을 내포하고, 환경자원의 보호와 경제적 번영을 의미한다. 지속가능성에 대한 심도 있는 이해는 이러한 환경적인 영향에 대한 고려뿐만 아니라 원료 및 자원채취, 이송, 생산 협력의 전반적인 순환을 다루어야 한다. 화학산업의 지속가능한 발전은 화학공정안전의 발전을 통한 상호보완적인 강화없이 이루어지기 어렵다. 이러한 관점에서 화학공정안전은 국제시장에서 경쟁력 강화의 기회라고도 할 수 있다. 화학공정안전의 변화하는 새로운 패러다임은 현존하는 시스템과 생산공정의 기본 디자인을 고려한 총체적 순환 전 과정으로부터 나온다. 이렇게 화학공정안전을 향상시키기 위해서는 관리 시스템을 포함한 정량적 위험성 평가 방법과 다양한 공정안전 데이터 및 지식베이스를 포함한 통합 스마트시스템의 개발이 필요하다. 본 논문에서는 화학산업안전의 전 과정 순환의 필요성에 대해 언급하였고, 이를 향상시키기 위한 공정안전 신기술에 대해 논의하였다. 변화하는 공정시스템공학에서 사고 없는 지속 가능한 산업의 발전을 위해서는 3 가지의 S, 즉 안전(Safety), 안정(Stability), 안보(Security)의 조합이 적절히 이루어져야 할 것이다.

시스템생물학의 한의학적 응용 (Application of Systems Biology to Traditional Korean Medicine)

  • 박영철;이선동
    • 대한예방한의학회지
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    • 제20권1호
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    • pp.99-110
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    • 2016
  • In Korea and China, traditional medicine's holistic approaches, based on the views of whole-body and whole-person, have been applied to make the solution of health problem. However, these holistic approaches of traditional korea or chinese medicine have been limited in interpreting their theories in a view of modern scientific aspects of medicine. This limitation seems to be mainly due to the reductionism approaches of modern scientific medicine. Traditionally, science has taken a reductionism approach; dissecting biological systems into their constituent parts and studying them in isolation. However, systems biology based on omics technologies is providing a new thought and method for traditional medicine's research and interpretation. Systems biology uses integrity study as the characteristic and bioinformatic technology as the key method for connecting reductionism and holism. Therefore, it has much in common with the theory of traditional medicine. It was reviewed that how systems biology is applied to traditional medicine in Korea and China. Also it was suggested that more future researches on interpretation between traditional medicine and systems biology must be focused on personalized medicine since systems biology will have a major impact on future personalized therapeutic approaches.

Integration of Optimality, Neural Networks, and Physiology for Field Studies of the Evolution of Visually-elicited Escape Behaviors of Orthoptera: A Minireview and Prospects

  • Shin, Hong-Sup;Jablonski, Piotr G.
    • Journal of Ecology and Environment
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    • 제31권2호
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    • pp.89-95
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    • 2008
  • Sensing the approach of a predator is critical to the survival of prey, especially when the prey has no choice but to escape at a precisely timed moment. Escape behavior has been approached from both proximate and ultimate perspectives. On the proximate level, empirical research about electrophysiological mechanisms for detecting predators has focused on vision, an important modality that helps prey to sense approaching danger. Studies of looming-sensitive neurons in locusts are a good example of how the selective sensitivity of nervous systems towards specific targets, especially approaching objects, has been understood and realistically modeled in software and robotic systems. On the ultimate level, general optimality models have provided an evolutionary framework by considering costs and benefits of visually elicited escape responses. A recent paper showed how neural network models can be used to understand the evolution of visually mediated antipredatory behaviors. We discuss this new trend towards integration of these relatively disparate approaches, the proximate and the ultimate perspectives, for understanding of the evolution of behavior of predators and prey. Focusing on one of the best-studied escape pathway models, the Orthopteran LGMD/DCMD pathway, we discuss how ultimate-level optimality modeling can be integrated with proximate-level studies of escape behaviors in animals.

작업 부하에 따른 운전자의 생체신호 처리 및 특성 분석 (Analysis and Processing of Driver's Biological Signal of Workload)

  • 허윤석;이재천;김윤년
    • 한국산업정보학회논문지
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    • 제20권3호
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    • pp.87-93
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    • 2015
  • 졸음 운전 등 운전자의 상태 변화에 따른 자동차 사고가 급증하고 있으며 이를 방지하기 위한 시스템 구축 및 운전자의 상태를 판단하는 알고리즘 개발이 요구되어 지고 있다. 본 논문에서는 모의 주행 시스템을 통한 운전자의 심박변이도, 산호 포화도 (SPO2), 체온을 측정하여 운전자의 상태를 알려 주는 실험을 수행하였다. 즉, 심박변이도 (Heart rate variability, HRV) 분석을 위해 운전자의 심전도(Electrocardiogram, ECG) 신호를 획득 한 후 심전도 P,QRS, T 파형 중 R peak 을 자동으로 검출하였고 이를 통해 구한 R-R interval을 이용하여 HRV의 주요 파라메타를 시간영역(time domain)으로 해석하여 작업 환경에 따른 운전자의 상태를 비교 분석하였다.

구법(灸法)에 대한 문헌적(文獻的) 고찰(考察) 및 최근 연구(硏究) 동향(動向) (The Review and Study Trend of Moxibustion)

  • 우현수;이윤호;김창환
    • Journal of Acupuncture Research
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    • 제19권4호
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    • pp.1-15
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    • 2002
  • Objective : To observe the biological responses and therapeutic effects of moxibustion and review the trend of related study. Methods : We searched and investigated the journals supplied by Pubmed online site and Je-Han Oriental Medical Academy homepage with the key word "moxibustion". Results : 1. The biological responses of moxibustion reveal on skelectal, digestive, urinary systems, especially blood, angiological systems. 2. The therapeutic effect of moxibustion are analgesic action, controls of excitation or inhibitation of nerve system, improvement of blood circulation, nutrition in organs, increase of absorption of pathlogical product, controls of secreting glands, care of tuberculosis, increase of natural healing power etc. 3. Moxibustions effects on diarrhea, edema, diabetus mellitus, hyperlipiemia, tinnitus, osteoporosis, facial palsy, myopia, pimple etc. 4. Most of moxibustion studys related on immunofunctional actions and renal functional actions. 5. To elevated quality of studies, we needs well-designed epeerimental methods, efficient secure of experimental groups, appropriate statistical verification, accumulations of knowledges about data research. Conclusions : We find out moxibustion is remakble on clinincal therapeutic effects, from now on much more studies are needed to develop this therapy.

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유량 및 부하가 변하는 상태에서의 양로드 유압실린더의 위치제어시스템 (Position Control System of a Double-end Rod Hydraulic Cylinder under Variable Flow Rate and Load Conditions)

  • 김대철;김동화;이재규;신범수
    • Journal of Biosystems Engineering
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    • 제34권5호
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    • pp.331-341
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    • 2009
  • A double-end rod hydraulic cylinder is widely used with a steering valve for the steering control system in large tractors. For the development of automatic steering controller, the feasibility of using a proportional control valve replacing the conventional manual steering valve to control the position of hydraulic steering cylinder was investigated in terms of the max. overshoot, the steady-state error and the rise time. A simulation model for the electrohydraulic steering system with load using AMESim package was developed to be valid so that the proper control algorithm could be chosen through the computer simulation. It could be concluded that the P-control algorithm was sufficient to control the electrohydraulic steering system, where the control frequency should be no greater than 20 Hz at the P-gain of 5. In particular, the performance of the developed steering controller was satisfactory even at the conditions of varying flow rates and loads.

Genes expression monitoring using cDNA microarray: Protocol and Application

  • Muramatsu Masa-aki
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2000년도 국제심포지움 및 추계학술대회
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    • pp.31-41
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    • 2000
  • The major issue in the post genome sequencing era is determination of gene expression patterns in variety of biological systems. A microarray system is a powerful technology for analyzing the expression profile of thousands of genes at one experiment. In this study, we constructed cDNA microarray which carries 2,304 cDNAS derived from oligo-capped mouse cDNA library. Using this hand-made microarray we determined gene expression in various biological systems. To determine tissue specific genes, we compared Nine genes were highly-expressed in adult mouse brain compared to kidney, liver, and skeletal muscle. Tissue distribution analysis using DNA microarray extracted 9 genes that were predominantly expressed in the brain. A database search showed that five of the 9 genes, MBP, SC1, HiAT3, S100 protein-beta, and SNAP25, were previously known to be expressed at high level in the brain and in the nervous system. One gene was highly sequence similar to rat S-Rex-s/human NSP-C, suggesting that the gene is a mouse homologue. The remaining three genes did not match to known genes in the GenBank/EMBL database, indicating that these are novel genes highly-expressed in the brain. Our DNA microarray was also used to detect differentiation specific genes, hormone dependent genes, and transcription-factor-induced genes. We conclude that DNA microarray is an excellent tool for identifying differentially expressed genes.

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