• Title/Summary/Keyword: Biological systems

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Editorial for Vol. 31, No. 2 (편집자 주: 31권 2호)

  • Kim, Young Hyo
    • Korean journal of aerospace and environmental medicine
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    • v.31 no.2
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    • pp.31-32
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    • 2021
  • In Vol. 31, No. 2, our journal prepared a review article, two original papers, and three case reports. First, autonomous systems are increasingly being introduced in aircraft systems. Therefore, it is crucial that flight crews are trained to adapt and handle these autonomous systems better. Consequently, we discussed crew resource management for handling autonomous systems. The fatigue of aviation workers is one of the biggest threats to aviation safety. Therefore, we analyzed the degree of fatigue in commercial aircraft pilots and evaluated the relationship between fatigue and their workload and the effect of fatigue on sleep. Since obesity has a significant impact on the health of aviation workers, we also comparatively analyzed the prevalence of obesity in Korea and Japan based on the data from the National Health and Nutrition Examination Survey. We defined cases that are difficult for aviation medical examiners to evaluate. This issue included cases of peripheral dizziness and tinnitus, cases of atopic dermatitis treated with biological agents, and cases of malignant tumors.

Frequency Responses of Ambulatory ECG Systems and Their Correction by a Compensation Circuit

  • Iwao, K.;Yokoi, A.;Suzuki, S.;Goto, T.;Doniwa, K.;Okajima, M.
    • Journal of Biomedical Engineering Research
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    • v.11 no.1
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    • pp.13-18
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    • 1990
  • Frequency responses of ambulatory electrocardiogram systems were measured. Phase shift was assessed by our improved Wagner's method. The characteristics of the systems were found much worse than that of ordinary ECG equipment both in gain and phase responses. The decay of -3dB in amplitude observed in 0.2Hz and the lead of 45 dog in phase was observed in 0.6Hz. In order to investigate which of these 2 responses play major role in generating false S -T deviation, mathe- matical filters were Composed in a computer and actual ECGs were fed. The false S-T deviation were found to be caused mostly by enormous lead in phase, and then, the compensation circuit to diminish the lead in phase was inserted in the commercial systemes. The compensated systems showed no false deviation in S-T segment.

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The Role of Process Systems Engineering for Sustainability in the Chemical Industries (화학공정 산업에서의 지속가능성과 공정시스템 공학)

  • Jang, Namjin;Dan, Seungkyu;Shin, Dongil;Lee, Gibaek;Yoon, En Sup
    • Korean Chemical Engineering Research
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    • v.51 no.2
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    • pp.221-225
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    • 2013
  • Sustainability, in general, means the protection of environmental resources and economic prosperity, with the consideration of the social, economic and environmental effect, as well as human health and the enhancement of life. Profound consideration about sustainability has to handle the overall cycle of feedstock, resource extraction, transportation and production in addition to the environmental effect. Sustainable development of the chemical industries should be carried out complementarily by strengthening the chemical process safety of the industries. In this respect, chemical process safety can be called an opportunity to enhance the compatibility internationally. Changing new paradigm in chemical process safety is formed from the overall life cycle considering basic design of existing systems and production processes. To improve the chemical process safety, the integrated smart system is necessary, comprising various chemical safety database and knowledge base and improved methods of quantitative risk analysis, including management system. This paper discussed the necessity of overall life cycle in chemical process safety and proposed new technology to improve the sustainability. To develop the sustainable industries in process systems engineering, three S, which include Safety, Stability and Security, will have to be combined appropriate.

Application of Systems Biology to Traditional Korean Medicine (시스템생물학의 한의학적 응용)

  • Park, Yeongchul;Lee, Sundong
    • Journal of Society of Preventive Korean Medicine
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    • v.20 no.1
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    • pp.99-110
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    • 2016
  • In Korea and China, traditional medicine's holistic approaches, based on the views of whole-body and whole-person, have been applied to make the solution of health problem. However, these holistic approaches of traditional korea or chinese medicine have been limited in interpreting their theories in a view of modern scientific aspects of medicine. This limitation seems to be mainly due to the reductionism approaches of modern scientific medicine. Traditionally, science has taken a reductionism approach; dissecting biological systems into their constituent parts and studying them in isolation. However, systems biology based on omics technologies is providing a new thought and method for traditional medicine's research and interpretation. Systems biology uses integrity study as the characteristic and bioinformatic technology as the key method for connecting reductionism and holism. Therefore, it has much in common with the theory of traditional medicine. It was reviewed that how systems biology is applied to traditional medicine in Korea and China. Also it was suggested that more future researches on interpretation between traditional medicine and systems biology must be focused on personalized medicine since systems biology will have a major impact on future personalized therapeutic approaches.

Integration of Optimality, Neural Networks, and Physiology for Field Studies of the Evolution of Visually-elicited Escape Behaviors of Orthoptera: A Minireview and Prospects

  • Shin, Hong-Sup;Jablonski, Piotr G.
    • Journal of Ecology and Environment
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    • v.31 no.2
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    • pp.89-95
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    • 2008
  • Sensing the approach of a predator is critical to the survival of prey, especially when the prey has no choice but to escape at a precisely timed moment. Escape behavior has been approached from both proximate and ultimate perspectives. On the proximate level, empirical research about electrophysiological mechanisms for detecting predators has focused on vision, an important modality that helps prey to sense approaching danger. Studies of looming-sensitive neurons in locusts are a good example of how the selective sensitivity of nervous systems towards specific targets, especially approaching objects, has been understood and realistically modeled in software and robotic systems. On the ultimate level, general optimality models have provided an evolutionary framework by considering costs and benefits of visually elicited escape responses. A recent paper showed how neural network models can be used to understand the evolution of visually mediated antipredatory behaviors. We discuss this new trend towards integration of these relatively disparate approaches, the proximate and the ultimate perspectives, for understanding of the evolution of behavior of predators and prey. Focusing on one of the best-studied escape pathway models, the Orthopteran LGMD/DCMD pathway, we discuss how ultimate-level optimality modeling can be integrated with proximate-level studies of escape behaviors in animals.

Analysis and Processing of Driver's Biological Signal of Workload (작업 부하에 따른 운전자의 생체신호 처리 및 특성 분석)

  • Heo, Yun Seok;Lee, Jae-Cheon;Kim, Yoon Nyun
    • Journal of Korea Society of Industrial Information Systems
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    • v.20 no.3
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    • pp.87-93
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    • 2015
  • The accidents caused by drivers while driving are considered as the major causes along with other causes such as conditions of roads, weather and cars. In this study, we investigated the driver's workloads under three different driving conditions (Weather, Driving time zone, and Traffic density) through analyzing biological signals obtained from a car driving simulator system. The proposed method is able to detect R waves and R-R interval calculation in the ECG. Heart rate variability (HRV) was investigated for the time domain to determine the changes in driver's conditions.

The Review and Study Trend of Moxibustion (구법(灸法)에 대한 문헌적(文獻的) 고찰(考察) 및 최근 연구(硏究) 동향(動向))

  • Woo, Hyun-su;Lee, Yun-ho;Kim, Chang-hwan
    • Journal of Acupuncture Research
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    • v.19 no.4
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    • pp.1-15
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    • 2002
  • Objective : To observe the biological responses and therapeutic effects of moxibustion and review the trend of related study. Methods : We searched and investigated the journals supplied by Pubmed online site and Je-Han Oriental Medical Academy homepage with the key word "moxibustion". Results : 1. The biological responses of moxibustion reveal on skelectal, digestive, urinary systems, especially blood, angiological systems. 2. The therapeutic effect of moxibustion are analgesic action, controls of excitation or inhibitation of nerve system, improvement of blood circulation, nutrition in organs, increase of absorption of pathlogical product, controls of secreting glands, care of tuberculosis, increase of natural healing power etc. 3. Moxibustions effects on diarrhea, edema, diabetus mellitus, hyperlipiemia, tinnitus, osteoporosis, facial palsy, myopia, pimple etc. 4. Most of moxibustion studys related on immunofunctional actions and renal functional actions. 5. To elevated quality of studies, we needs well-designed epeerimental methods, efficient secure of experimental groups, appropriate statistical verification, accumulations of knowledges about data research. Conclusions : We find out moxibustion is remakble on clinincal therapeutic effects, from now on much more studies are needed to develop this therapy.

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Position Control System of a Double-end Rod Hydraulic Cylinder under Variable Flow Rate and Load Conditions (유량 및 부하가 변하는 상태에서의 양로드 유압실린더의 위치제어시스템)

  • Kim, Dae-Cheol;Kim, Dong-Hwa;Lee, Jae-Kyu;Shin, Beom-Soo
    • Journal of Biosystems Engineering
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    • v.34 no.5
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    • pp.331-341
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    • 2009
  • A double-end rod hydraulic cylinder is widely used with a steering valve for the steering control system in large tractors. For the development of automatic steering controller, the feasibility of using a proportional control valve replacing the conventional manual steering valve to control the position of hydraulic steering cylinder was investigated in terms of the max. overshoot, the steady-state error and the rise time. A simulation model for the electrohydraulic steering system with load using AMESim package was developed to be valid so that the proper control algorithm could be chosen through the computer simulation. It could be concluded that the P-control algorithm was sufficient to control the electrohydraulic steering system, where the control frequency should be no greater than 20 Hz at the P-gain of 5. In particular, the performance of the developed steering controller was satisfactory even at the conditions of varying flow rates and loads.

Genes expression monitoring using cDNA microarray: Protocol and Application

  • Muramatsu Masa-aki
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2000.11a
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    • pp.31-41
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    • 2000
  • The major issue in the post genome sequencing era is determination of gene expression patterns in variety of biological systems. A microarray system is a powerful technology for analyzing the expression profile of thousands of genes at one experiment. In this study, we constructed cDNA microarray which carries 2,304 cDNAS derived from oligo-capped mouse cDNA library. Using this hand-made microarray we determined gene expression in various biological systems. To determine tissue specific genes, we compared Nine genes were highly-expressed in adult mouse brain compared to kidney, liver, and skeletal muscle. Tissue distribution analysis using DNA microarray extracted 9 genes that were predominantly expressed in the brain. A database search showed that five of the 9 genes, MBP, SC1, HiAT3, S100 protein-beta, and SNAP25, were previously known to be expressed at high level in the brain and in the nervous system. One gene was highly sequence similar to rat S-Rex-s/human NSP-C, suggesting that the gene is a mouse homologue. The remaining three genes did not match to known genes in the GenBank/EMBL database, indicating that these are novel genes highly-expressed in the brain. Our DNA microarray was also used to detect differentiation specific genes, hormone dependent genes, and transcription-factor-induced genes. We conclude that DNA microarray is an excellent tool for identifying differentially expressed genes.

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