• Title/Summary/Keyword: Biological information

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A Study on the Bleeding Detection Using Artificial Intelligence in Surgery Video (수술 동영상에서의 인공지능을 사용한 출혈 검출 연구)

  • Si Yeon Jeong;Young Jae Kim;Kwang Gi Kim
    • Journal of Biomedical Engineering Research
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    • v.44 no.3
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    • pp.211-217
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    • 2023
  • Recently, many studies have introduced artificial intelligence systems in the surgical process to reduce the incidence and mortality of complications in patients. Bleeding is a major cause of operative mortality and complications. However, there have been few studies conducted on detecting bleeding in surgical videos. To advance the development of deep learning models for detecting intraoperative hemorrhage, three models have been trained and compared; such as, YOLOv5, RetinaNet50, and RetinaNet101. We collected 1,016 bleeding images extracted from five surgical videos. The ground truths were labeled based on agreement from two specialists. To train and evaluate models, we divided the datasets into training data, validation data, and test data. For training, 812 images (80%) were selected from the dataset. Another 102 images (10%) were used for evaluation and the remaining 102 images (10%) were used as the evaluation data. The three main metrics used to evaluate performance are precision, recall, and false positive per image (FPPI). Based on the evaluation metrics, RetinaNet101 achieved the best detection results out of the three models (Precision rate of 0.99±0.01, Recall rate of 0.93±0.02, and FPPI of 0.01±0.01). The information on the bleeding detected in surgical videos can be quickly transmitted to the operating room, improving patient outcomes.

Effects of sodium diacetate and microbial inoculants on fermentation of forage rye

  • Yan Fen Li;Eun Chan Jeong;Li Li Wang;Hak Jin Kim;Farhad Ahmadi;Jong Geun Kim
    • Journal of Animal Science and Technology
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    • v.65 no.1
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    • pp.96-112
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    • 2023
  • Rye (Secale cereale L.) is a valuable annual forage crop in Korea but there is limited information about the impact of chemical and biological additives on fermentation characteristics of the crop. This experiment was conducted to investigate fermentation dynamics of wilted forage rye treated with the following six additives; control (no additive), sodium diacetate applied at 3 g/kg wilted forage weight (SDA3), 6 g/kg wilted forage weight (SDA6), inoculations (106 CFU/g wilted forage) of Lactobacillus plantarum (LP), L. buchneri (LB), or LP+LB. The ensiled rye sampled at 1, 2, 3, 5, 10, 20, 30, and 45 days indicated that the acidification occurred fast within five days of storage than the rest of the storage period. The microbial inoculants decline the pH of ensiled forage, more rapidly than the control or SDA treated, which accompanied by the decrease of water-soluble carbohydrates and increase of lactic acid. Compared with the control silage, all treatments suppressed ammonia-nitrogen formation below to 35 g/kg DM throughout the sampling period. Suppression of total microbial counting occurred in SDA6, LP, and LP + LB. The lactic acid production rates were generally higher in microbial inoculation treatments. Acetic acid concentration was lowest in the LP-treated silage and highest in the SDA- and LB-treated silages. The in vitro dry matter (DM) digestibility and total digestible nutrients were the highest in the silage treated with SDA (6 g/kg) at day 45 of ensiling. Based on lower ammonia-nitrogen concentrations and higher feed value, ensiling forage rye treated with SDA at 6 g/kg is promising through enhanced silage quality.

Allergic inflammatory inhibitory effect screening using natural extracts and single substances (천연추출물 및 단일물질을 이용한 알러지 염증억제효과 스크리닝)

  • Park, Sung ah;Jang, Yoon-sung
    • Journal of Convergence for Information Technology
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    • v.12 no.2
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    • pp.213-220
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    • 2022
  • In this study, a functional study was conducted to confirm the inhibitory effect of IL-6 and TFN-α, which are allergic inflammation inhibitory effects, using natural extracts 640 types of substances. Of the 640 types, 36 substances showed 100% cell viability, and among the extracts showing the IL-6 inhibitory effect, 8 substances showed an inhibitory effect similar to that of cyclosporin A, and 5 substances showed an inhibitory effect on TFN-α. In particular, two types of extracts showing a common inhibitory effect on IL-6 and TFN-α showed an anti-allergic anti-inflammatory effect and a strong anti-allergic anti-inflammatory effect in Hagocho and Snow lotus extract. It is thought that these contents can be used as a functional natural cosmetic material for allergy-inflammation suppression using natural extracts.

An Influence of the Fourth Industrial Revolution on International Trade and Countermeasure Strategies to Promote Export in Korea (4차 산업혁명이 무역에 미칠 영향과 이에 대비한 수출촉진전략)

  • Lee, Byung-Mun;Jeong, Hee-Jin;Park, Kwang-So
    • Korea Trade Review
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    • v.42 no.3
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    • pp.1-24
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    • 2017
  • This study investigates any possible influences of the fourth industrial revolution on international trade in Korea and suggests strategies to promote export of Korea in order to secure one of the biggest international trade countries. The fourth industrial revolution is the fourth major industrial era since the third industrial revolution in the 18th century which used electronics and information technology to automate production. This can be characterized as a range of emerging technologies that are fusing the physical, digital and biological worlds, and impacting all disciplines, economies and industries. Since this revolution is expected to have effects on international trade as well as whole industrial society, it examines how it may affect international trade of Korea in terms of the subject, the object, markets and forms of international trade. After that, it provides the strategies to promote Korean export in order to overcome the risks around the low economic growth of the recent years and the depressed domestic economy.

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Characterization of a Potential Probiotic Lactiplantibacillus plantarum LRCC5310 by Comparative Genomic Analysis and its Vitamin B6 Production Ability

  • Yunjeong Lee;Nattira Jaikwang;Seong keun Kim;Jiseon Jeong;Ampaitip Sukhoom;Jong-Hwa Kim;Wonyong Kim
    • Journal of Microbiology and Biotechnology
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    • v.33 no.5
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    • pp.644-655
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    • 2023
  • Safety assessment and functional analysis of probiotic candidates are important for their industrial applications. Lactiplantibacillus plantarum is one of the most widely recognized probiotic strains. In this study we aimed to determine the functional genes of L. plantarum LRCC5310, isolated from kimchi, using next-generation, whole-genome sequencing analysis. Genes were annotated using the Rapid Annotations using Subsystems Technology (RAST) server and the National Center for Biotechnology Information (NCBI) pipelines to establish the strain's probiotic potential. Phylogenetic analysis of L. plantarum LRCC5310 and related strains showed that LRCC5310 belonged to L. plantarum. However, comparative analysis revealed genetic differences between L. plantarum strains. Carbon metabolic pathway analysis based on the Kyoto Encyclopedia of Genes and Genomes database showed that L. plantarum LRCC5310 is a homofermentative bacterium. Furthermore, gene annotation results indicated that the L. plantarum LRCC5310 genome encodes an almost complete vitamin B6 biosynthetic pathway. Among five L. plantarum strains, including L. plantarum ATCC 14917T , L. plantarum LRCC5310 detected the highest concentration of pyridoxal 5'-phosphate with 88.08 ± 0.67 nM in MRS broth. These results indicated that L. plantarum LRCC5310 could be used as a functional probiotic for vitamin B6 supplementation.

Distribution and Bionomics of the Argentine Ant Linepithema humile (Mayr) (Hymenoptera: Formicidae: Dolichoderinae)

  • Min-Ji Lee;Young-Gyu Ban;Heejo Lee;Young Ha Kim;Dayeong Kim;Nang-Hee Kim;Dong Eon, Kim
    • Proceedings of the National Institute of Ecology of the Republic of Korea
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    • v.4 no.3
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    • pp.104-114
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    • 2023
  • In this study, the distribution, bait preference, hosts, symbionts, habitat status, and cytochrome c oxidase subunit-I sequences of the ant Linepithema humile were analyzed. This species habitat comprised approximately 1.5 km along stone crevices, flower gardens, roadsides, and container yards in the vicinity of Busan station, Korea. Feeding activity of this species was confirmed in 9 species of 7 families of plants. Which was approximately 14% of total flora (63 species of 37 families) in the studied area. Particularly, it was observed that Dendranthema indicum and Camellia japonica were the most frequently visited. Further, we verified that they interacted with four species of aphids. We identified 22 species of ants (17 genera, 4 subfamilies) inhabiting the Busan station area, including L. humile, Tetramorium tsushimae, Nylanderia flavipes and the alien species Paratrechina longicornis. In areas where L. humile was the dominant species, the habitat of local native ants was reduced by approximately 30%. Bait preference was ranked in the following order: jelly, water with glucose (25%), and yogurt, with the highest preference for baits containing sugar and protein. The 630-bp cytochrome c oxidase subunit-I sequences of the local L. humile populations were 99% identical to those of L. humile in the National Center for Biotechnology Information database, and the Argentine ants that invaded Korea had a sequence identical to that of other invasive populations from China, Japan, and New Zealand. As L. humile rapidly increases due to domestic adaptation, continuous monitoring and control strategy for eradication are needed to protect domestic biodiversity.

Development of the Substrate Utilization and Respiration Model by the Step Growth Concept (단계별 성장 개념의 기질 이용과 미생물 호흡모델 개발)

  • Kim, Youn Kwon;Seo, In Seok;Kim, Hong Suck;Kim, Ji Yeon
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.26 no.4B
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    • pp.433-437
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    • 2006
  • Recently, mathematical modeling for the activated sludge process is important to design and control of wastewater treatment plant. Nevertheless, there is a lack of information regarding the pathway of substrate utilization between external and internal substrates in biological nutrient removal (BNR). In this research, a new activated sludge model (step growth model) is proposed and compare with ASM No.3. This model structure is consist of five processes; aerobic storage, growth on external substrate and stored intercellular storage compounds (ISCs), endogenous respiration and aerobic respiration of ISCs. The predicted results by the step growth model were more good accordance with the results of oxygen utilization rate (OUR) and TCOD experiment than that of the ASM No.3.

A Study on Official Development Assistance (ODA) in Science and Technology in Korea (최근 국내 과학기술 ODA 동향과 부처별 사업분류 체계 및 내용에 대한 현황 분석)

  • Jeong, Seongpil;Cho, Ik Hyun;Seok, Dockko;Kim, Yong-soo;Moon, Ji-hyun;Yoon, Jeyong
    • Journal of Appropriate Technology
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    • v.4 no.2
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    • pp.96-107
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    • 2018
  • Korea is the only country which had been helped from developed countries and is now helping developing countries. Various ODA programs have been actively conducted by Korea after joining the OECD in 1999. Recently, Korea increases the ODA funds to achieve the goal of ODA/GNI ratio 0.2% until 2020. Science and technology ODA (so called appropriate technology) is a huge issue because the departments or agencies of Korean government also increase ODA funds. This research will provide the information of Korean science and technology ODA according to the research areas and funding sources since 1999.

Whole Genome Sequencing of Two Musa Species Towards Disease Resistance and Fiber Quality Improvement

  • John Ivan Pasquil;Richellen Plaza;Roneil Christian Alonday;Damsel Bangcal;Julianne Villela;Antonio, Lalusin;Maria Genaleen Diaz;Antonio Laurena
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2022.10a
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    • pp.32-32
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    • 2022
  • Abaca (Musa textilis L. Nee) is a native Musa species from the Philippines known for its natural fiber. Abaca fiber a.k.a. Manila hemp extracted from its pseudostems is considered one of the strongest fibers in the world. This is used for commodities such as ropes, papers, and money bills. Abaca is vulnerable to pests and diseases such as the Abaca Bunchy Top Disease (ABTD) caused by Abaca Bunchy Top Virus (ABTV) and Banana Bunchy Top Virus (BBTV). Inosa, one of the varieties of abaca utilized in the Philippines, is highly susceptible to ABTD. In contrast, Pacol (Musa balbisiana L.), a close relative of abaca, is highly resistant to the same disease. Here, we report the sequencing and de novo genome assembly of both abaca var. Inosa and banana var. Pacol. A total of ~16 Gb and ~21 Gb raw reads for Inosa and Pacol, respectively, were generated using Pacbio Hifi sequencing method and assembled with Hifiasm. High-quality de novo assemblies of both Musa species with 99% recovered as per BUSCO analysis were obtained. The assembled Inosa genome has a total length of ~654 Mb and N50 of 7 Mb while Pacol has a total length of 527 Mb and N50 of 3 Mb which are close to their estimated genome size of ~638 Mb and ~503 Mb, respectively. The information that can be derived from the de novo assembled genomes would provide a solid foundation for further research in disease resistance and fiber quality improvement in abaca.

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Effect of Demographic Factors, Radiation Knowledge Level, Radiation Awareness on Radiation Benefit by Hierarchical Regression Analysis Model (위계적 회귀분석 모형에 의한 인구학적 요인, 방사선 지식수준, 방사선 인식도가 방사선 이익성에 미치는 영향)

  • Myeong-Hoon Ji;Youl-Hun Seoung
    • Journal of radiological science and technology
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    • v.46 no.5
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    • pp.435-444
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    • 2023
  • The purpose of this study was to analyze the factors that demographic factors, radiation knowledge level, and radiation awareness could be affecting the benefits of radiation. From July 2022 to July 2023, after receiving consent to participate by using the link of Naver through Social Network Service (SNS) for the general public, 312 people were surveyed by self-registration method without collecting personal information. The questionnaire consisted of a total of 25 questions following demographic factors (5 questions including age group by life cycle, sex, monthly household income, residence), radiation knowledge level (8 questions including basic physical, biological effects, radiation protection technology), radiation awareness (12 questions including risk, management, benefit). Independent sample T-test and ANOVA tests were performed for significant differences in the average radiation awareness between variables, and hierarchical regression was performed to identify influencing factors on radiation benefits. As a result, the benefit of radiation was significantly high among the radiation awareness, but the awareness of the danger of radiation was insufficient to the level of recognizing it as safe. Men had significantly higher awareness of radiation management and benefits than women, and the awareness of radiation management was significantly higher in the middle class with a monthly household income of 4.31 million won or more. The higher the knowledge level of radiation, the higher the awareness of the benefits of radiation. The factors that had a positive effect on radiation benefits were the high level of radiation knowledge and awareness of radiation management.