• Journal of Korea Technology Innovation Society
• /
• v.11 no.2
• /
• pp.219-240
• /
• 2008

This paper aims to suggest a policy for biological resource based on a comprehensive understanding on biological resources. Biological resources are different from traditionally recognized viable organisms (Biodiversity) in ecosystems. Biological resources are culturable and replicable resources of living organisms such as tissues, cells and genes. Moreover, biological resources include human-derived biological materials. Biological resources is not simply a matter of science and technology. Biological resources should be dealt with as national resources. There are many international issues regarding biological resources, such as intellectual property rights (IPRs), safety on handling and distribution, material transfer agreements (MTAs) for mutual benefits and biological standards. Ethical debates are also being raised because biological resources are related with human-derived biological materials. Every nation has tendency to adopt its government policies to strengthen its sovereignty on biological resources and international cooperation. In addition, international linkages are essential for providing enhanced worldwide accessibility to biological resources. Japan has shown several international initiatives in the field of biological resources. Korea has just begun to design appropriate policies for the use and R&D of biological resources. Therefore, this paper suggests the following needs: 1) policy at the national level beyond the interests of researchers, 2) inter-ministerial coordination across government ministries, 3) expansion of scope and size of each BRC (Biological Resource Centers), and 4) building networks and systems such as national information center, representative centers by field, and each BRC.

• Journal of Korean Biological Nursing Science
• /
• v.8 no.2
• /
• pp.61-72
• /
• 2006

Purpose: This study was to examine the frequency, distribution and characteristics of researches using biological measurement published from 2000 to 2004 in 10 major nursing journals in Korea, Design: Literature analysis. Method: Journals including papers using biological measurements, publishing year, research design and outcome variables were analyzed. Results: 1. Researches using biological measurement were 318(13.3%). 2. Researches using biological measurement in the Korean Academy of Nursing were highest(97papers, 17.5%) among the nursing journals. The proportion of papers using biological measurement to total number of papers was the highest in the Journal of Korean Biological Nursing Science as 77.3%(51papers). 3. The 233 papers(73.3%) were experimental researches among 318 papers using biological measurement which showed the highest proportion. 4. Patients were highest subjects of researches using biological measurement(197papers, 61.9%). 5. Blood test was most frequently used as physiological variables from 2001 to 2004. Conclusion: Researches using biological measurement of 10 Korean Nursing Journals in year 2000-year 2004 were very low. We need more researches using biological measurement to provide more objective evidence for nursing practice.

• Journal of the Korean Society of Costume
• /
• v.65 no.1
• /
• pp.118-135
• /
• 2015

In recent years, smart clothing had been developed in order to better detect and monitor physical movement of the patient, so that such activities such as location identification and biometric recognition could be done. However, most of the sensing devices of smart clothing were limited to smart sensing sports clothing and the designs did not consider the physical characteristics and the behavior of the wearer. Therefore, this study aimed to create an open protection system by developing a wearable sensing device for health monitoring and location information. For this purpose, this study developed eleven types of wearable sensing design that could be commercially sold and worn by people who needed their biological information to be constantly monitored. The study conducted four tests in order to develop three types of sensing devices for various sensing wears. The purpose of this study was to expand the user rang of smart sensing wears, and provide a foundation for the development of distinctive wearable sensing devices reflecting the user. Furthermore, contribute to the design for the person subject to protection.

• Journal of the Korean Society of Environmental Restoration Technology
• /
• v.20 no.6
• /
• pp.161-180
• /
• 2017

As the competition for securing cross-border biological sovereignty becomes intensified due to the adoption of the Nagoya Protocol, this study analyzed patent trends only for freshwater plants in order to secure national biological sovereignty. As a result, freshwater plants include a total of 68 genera and 128 species, and a total of 60 genera and 3,256 patents were surveyed. Among them, iris was the most industrialized, 14.71% followed by angelica(8.48%) and Mentha(6.94%). However, unconfirmed eight genera (Aneilema, Artemisia Cabomba, Nymphoides, Pistia stratiotes L., Pseudoraphis Griff., Ruppia) are not patented freshwater plants and it is expected that patent entry is high and barrier is low in the future. Based on patent results, Cooperative Patent Classification analysis was carried out and as a result, a total of 15 industry sectors were derived. And biopharmaceutical(30.24%) was found to be the most industrialized industry sector followed by agricultural chemistry (28.89%), biochemical industry (16.25%). In the biomedical industry, angelica(17.74%) was the most used and Iris (9.55%), Sium(20.56%) and angelica (20.48%) were found to be the most used in agricultural chemistry, biochemical industry and bio food industry, respectively. The analysis of detailed industry fields for 15 industry sectors showed that medicines of unknown structure containing substances from plants (37.77%), raw materials (46.57%) such as insect repellants, attracting agents and preparation of peptides(16.82%) with more than 21 amino acids were most frequently used in biopharmaceutical, agricultural chemistry and biochemical industry, respectively. This study is of significance as a basic data to know which freshwater plants are used in which field in order to secure biological sovereignty and patent analysis is considered necessary to continuously secure the biological sovereignty for freshwater plants.

• Genomics & Informatics
• /
• v.7 no.3
• /
• pp.168-170
• /
• 2009

The explosion in biological data resulting from high-throughput experiments requires new software tools to manipulate and display pathways in a way that can integrate disparate sources of information. A visual Java-based CAD tool for drawing and annotating biological pathways with semiautomatic image-processing features is described in this paper. The result of the image-editing process is an XML file for the appropriate links. This tool integrates the pathway images and XML file sources. The system has facilities for linking graphical objects to external databases and is capable of reproducing existing visual representations of pathway maps.

• Proceedings of the Korean Institute of Intelligent Systems Conference
• /
• 2006.05a
• /
• pp.45-48
• /
• 2006

The system that can generate biological brain information processing mechanism more precisely may have several abilities such as exact cognition, situation decision, learning and inference, and output decision. In this paper, to implement high level information processing and thinking ability in a complex system, the information processing layer based on the biological brain is introduced. The biological brain information processing mechanism, which is analyzed in this paper, provides fundamental information about intelligent engineering system, and the design of the layer that can mimic the functions of a brain through engineering definitions can efficiently introduce an intelligent information processing method having a consistent flow in various engineering systems. The applications proposed in this paper are expected to take several roles as a unified model that generates information process in various areas, such as engineering and medical field, with a dream of implementing humanoid artificial intelligent system.

• Proceedings of the KIEE Conference
• /
• 1994.07a
• /
• pp.85-87
• /
• 1994

Feeding biological cells one by one is the key point in the manipulation of cells. The conventional valve systems have many difficulties in feeding cells one by one, because they shut the whole flow of fluids when they are closed and have possibilities of breaking the fragile cells. They need some other equipments for continuous supply of suspension and to protect the cells. We design a check valve for feeding biological cells one by one using polyimide all the silicon substrate. The cells are fed by hydraulic pressure through the isotropically etched cavity. When the suspension flows continuously along the channel the valve is bent by hydraulic pressure and a cell is fed to the outlet. We have studied a cell fusion device fabricated with polyimide and electroplating. If the designed check valve is located in front of the cell fusion device it is helpful to fuse two different kinds of cells.

• The Journal of Information Technology
• /
• v.9 no.1
• /
• pp.33-39
• /
• 2006

This study is for the contents of development to the hardware system and software driving algorithm to implement the frequency band of about 7KHz los pass digital filter which has the cut-off frequency of 392Hz by interfacing of a microprocessor with its peripheral analog-to-digital converter chip and digital-to-analog converter chip. The simplicity of digital filter design without difficulty and the implementation of programmed digital filter can be realized by providing the interfacing method to implement the law pass digital filter for the biological signals and the realization method of computer algorithm by a microprocessor.

• Journal of Integrative Natural Science
• /
• v.5 no.1
• /
• pp.1-5
• /
• 2012

Quantitative structure-activity relationship (QSAR) methodologies have been applied for many years, to correlate the relationship between physicochemical properties of chemical substances and their biological activities to generate a statistical model for prediction of the activities of new chemical entities. The basic principle behind the QSAR models is that, how structural variation is responsible for the difference in biological activities of the compounds. 3D-QSAR has emerged as a natural extension to the classical Hansch and Free-Wilson approaches, which develops the 3D properties of the ligands to predict their biological activities using various chemometric techniques (PLS, G/PLS, ANN etc). It has served as a valuable predictive tool in the design of pharmaceuticals and agrochemicals. This review seeks to provide different 3D-QSAR approaches involved in drug designing process to develop structure-activity relationships and also discussed the fundamental limitations, as well as those that might be overcome with the improved methodologies.

• Biotechnology and Bioprocess Engineering:BBE
• /
• v.5 no.4
• /
• pp.275-287
• /
• 2000

Fermentation strategies for recombinant protein production in Pichia pastoris have been investigated and are reviewed here. Characteristics of the expression system, such as phenotypes and carbon utilization, are summarized. Recently reported results such as growth model establishment, app58lication of a methanol sensor, optimization of substrate feeding strategy, DOstat controller design, mixed feed technology, and perfusion and continuous culture are discussed in detail.