• Title/Summary/Keyword: Biological Engineering

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A study on the food clean room system observing the regulations of HACCP (HACCP의 환경 최적화를 위한 식품 클린룸 설계에 관한 연구)

  • Won, Young-Jae;Suh, Kee-Won
    • Proceedings of the SAREK Conference
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    • 2009.06a
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    • pp.520-526
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    • 2009
  • This study proposed the optimum design values for the biological clean room system observing the regulations of Hazard Analysis Critical Control Point (HACCP). Even though the standard for industrial clean room system has been well established, the basis for biological food clean room system is the first stage. In order to prevent the contaminations in advance for food storages, processes, and distributions, the criterion of Hazard Analysis Critical Control Point is positively required. This study also suggested the possible ways of how to avoid the hazardous contaminations.

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Functional Genomics in the Context of Biocatalysis and Biodegradation

  • Koh Sung-Cheol;Kim Byung-Hyuk
    • Proceedings of the Microbiological Society of Korea Conference
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    • 2002.10a
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    • pp.3-14
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    • 2002
  • Functional genomics aims at uncovering useful information carried on genome sequences and at using it to understand the mechanisms of biological function. Elucidating the unknown biological functions of new genes based upon the genomics rationales will greatly speed up the extensive understanding of biocatalysis and biodegradation in biological world including microorganisms. DNA microarrays generate a system for the simultaneous measurement of the expression level of thousands of genes in a single hybridization assay. Their data mining (transcriptome) strategy has two categories: differential gene expression and coordinated gene expression. Furthermore, measurement of proteins (proteome) generates information on how the transcribed sequences end up as functional characteristics within the cell, and quantitation of metabolites yields information on how the functional proteins act to produce energy and process substrates (metabolome). Various composite functional genomics databases containing genetic, enzymatic and metabolic information have been developed and will contribute to the understanding of the life blue print and the new discoveries and practices in biocatalysis and biodegradation that could enrich their industrial and environmental applications.

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The Comparison with SAR Patterns of Biological Objects Contacted with Coaxial Waveguide Antenna Using the FDTD Method

  • Koo, S.M.;Kwon, K.H.;Lee, C.W.;Won, C.H.;Kim, M.N.;Cho, J.H.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.11
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    • pp.272-275
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    • 1997
  • Noninvasive multifrequency microwave radiometry using coaxial waveguide antenna has been investigated for a homogeneous and our layer human body model. We derived finite-difference time-domain(FDTD) algorithm and equation of MUR and generalized perfectly matched layer(GPML) absorbing boundary conditions(ABCs) in cylindrical coordination. The coupling between coaxial waveguide antenna and a biological object was analyzed by use of the FDTD method using MUR and GPML ABCs to obtain the absorbed power patterns in the media. The specific absorption rates(SAR) distribution which was corresponding to the temperature distribution was calculated in each region by use of the steady-state response in FDTD method. The SAR patterns of FDTD method using MUR ABCs was compared with those of FDTD method using GPML ABCs.

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Fabrication and Characteristics of In-Plane Type Micro Piezoelectric Micro Grippers with Pneumatic Lines for Biological Cells and Micro Parts Handling (바이오 셀 및 마이크로 부품 handling을 위한 pneumatic line을 갖는 in-plane 형 마이크로 압전 그리퍼 제조 및 특성)

  • Park J.S.;Park K.B.;Shin K.S;Moon C.W.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2006.05a
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    • pp.501-502
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    • 2006
  • In-plane type micro piezoelectric micro grippers with pneumatic lines for manipulation biological cells and micro parts were designed, fabricated, and characterized. Micro grippers were fabricated through the final micro-sanding process after wafer level bonding between the etched 4' Si wafer with pneumatic channels and 4' glass wafer. Displacements between two jaws of fabricated micro grippers were linearly increased with applying voltages to piezoelectric actuator. In the case of applying 80 V, the displacement between two jaws was $160{\mu}m$. Using fabricated micro grippers, manipulation tests for biological cell and micro parts with the sizes less than $100{\mu}m$ are in process.

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The Effect of Salinity on Biological Nutrient Removal in SBR (SBR공정에서 영양염류 제거에 대한 염분의 영향)

  • Song, Changsoo;Oh, Junseung
    • Journal of Korean Society on Water Environment
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    • v.18 no.3
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    • pp.237-243
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    • 2002
  • The effect of a salinity on the performance of a biological nutrient removal system was investigated using a model SBR(Sequencing Bach Reactor) system. The system was operated at a 12hr, 18hr, 24hr, and 36hr HRT with a salinity level of 20,000mg/L and compared with a system similarly operated with fresh water. The influent salinity level of 8,000 mg/L does not have a significant effect on BOD removal efficiency, there is a noticeable decrease in BOD removal rate from 10,000 mg Cl-/L. The Nitrogen could be removed from the saline wastewater with the same efficiency as for the fresh water because of low C/N ratio in anoxic period. The excess biological phosphorous removal is highly affected by the increase in the influent salinity. The efficiency is decreased from 96.6% to 43.4% when the influent salinity is increased from 0 to 20,000mg/L.

Implementation of Biological Information System Using Microprocessor(I)-Scanconverter- (마이크로프로세서를 이용한 생체정보시스템의 구성에 관한 연구(I)-환자감시 장치용 Scanconverter를 중심으로)

  • 박상희;김원기
    • Journal of Biomedical Engineering Research
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    • v.7 no.1
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    • pp.3-10
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    • 1986
  • In this paper, a scanconverter which displays the biological signals of low frequency on CRT for the purpose of easy read-out is attempted to design for using the CRTC, and it stows some good effectivenesses The results obtained in this experiment are as follows : (1) Using only one chip, CRT controller, it can display both waveforms and characters simultaneously. (2) The flexibility of CPU program can be obtained using the sub-microproce ssor function of CRTC chip. (3) The trend of digital data is possible through the graphic function (4) The vibration of displayed waveform can be prevented using the chip simplification and the trigger signal of one chip. (5) Operation with microprocessor malies the expansion and interface easy.

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Simulated Moving Bed [SMB] (모사 이동층 크로마토그래피)

  • Lee Chong-Ho;Koo Yoon-Mo
    • KSBB Journal
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    • v.20 no.3
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    • pp.192-196
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    • 2005
  • Chromatography has been a method of choice in the separation of complex biological mixtures for the analytical purpose in particular for the last half of century. In current years, chromatographic method extends its use to the preparative separation where the productivity per resin amount and solvent use become a matter of concern. Recently, simulated moving bed (SMB) method which claims high separation efficiency of the ideal counter-current moving bed chromatography has become a workhorse of preparative separation. SMB technology was developed in the early 1960s for large-scale hydrocarbon separation by UOP and approximately 120 Sorbex units have been licensed to date. Recently, SMB separation technology has been successfully extended from hydrocarbons and sugars to fine chemicals, particularly biochemicals, from laboratory to pilot to production plant. In this paper, the current status of SMB and its modifications were reviewed.

A Study on the Detecting of Noncontact Biosignal using UWB Radar (UWB 레이더를 이용한 비접촉 생체신호 검출에 관한 연구)

  • Lee, Yonggyu;Cho, Joonggil;Kim, Taesung
    • Journal of the Korea Safety Management & Science
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    • v.21 no.4
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    • pp.1-6
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    • 2019
  • This study relates to acquiring biological signal without attaching directly to the user using UWB(Ultra Wide Band) radar. The collected information is the respiratory rate, heart rate, and the degree of movement during sleep, and this information is used to measure the sleep state. A breathing measurement algorithm and a sleep state detection algorithm were developed to graph the measured data. Information about the sleep state will be used as a personalized diagnosis by connecting with the medical institution and contribute to the prevention of sleep related diseases. In addition, biological signal will be linked to various sensors in the era of the 4th industrial revolution, leading to smart healthcare, which will make human life more enriching.

A Development Study on High Quality Drinking Water Production by the Biological Activated Carbon/immersed Membrane Filtration System

  • Inoue, Shiro;Iwai, Tosinori;Isse, Masaaki;Terui, Taturo
    • Proceedings of the Membrane Society of Korea Conference
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    • 2001.07a
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    • pp.155-162
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    • 2001
  • Advanced drinking water production systems, which not only good quality product water, but also provide easy management and mainenance of facilities, and operate on a smaller site area, have been expected to be developed for some time. We are going ahead with a program to deveop an advanced drinking water production system, using immersed membrane filtration combined with biological activated carbon, to meet the need described above. The demonstration plant tests been conducted with surface water from the Yodo-river since Dec. 1998 to measure treatment performance, reliability, and controllability of the system. The quality of product water has consistently remained at a very high level for about 2 years under controlled conditions. Results showed that the re-circulation granular biological activated carbon could suppress the increase of membrane pressure difference and promote a reduction of dissolved organic matter. (This work has been conducted along the ACT21 Programs.)

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Polymer Surfaces for Cell Adhesion I. Surface Modification of Polymers and ESCA Analysis (세포적합성 고분자 표면에 관한 연구 I. 고분자 표면 개질과 ESCA 분석)

  • 이진호;강길선
    • Journal of Biomedical Engineering Research
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    • v.10 no.1
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    • pp.43-52
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    • 1989
  • We modified polymer surfaces, polyethylene, polystyrene and polyester, to improve cellcompatibility. For surface modification of the polymers, we used various surface treatment methods; physicochemical oxidation methods such as plasma discharge, corona discharge, sulfuric acid and chloric acid treatments, and biological methods such as adsorption of plasma protein and fibronectin onto the polymer surfaces. The treated polymer surfaces were characterized by electron spectroscopy for chemical analysis ( ESCA ). The physicochemically treated polymers showed different surface chemical structures depending on the treated methods. The sulfuric acid-treated surfaces showed greater carboxyl groups than those of plasma- or corona- treated surfaces, while the chloric acid-treated one showed high density of hydroxyl group on the surface. By the biological treatments, the surfaces were uniformly coated with proteins. The fibronectin adsorbed on the surface seems to have unique properties for cell binding.

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