• 제목/요약/키워드: Biological Effect

검색결과 5,992건 처리시간 0.036초

영적중재의 신체적, 심리적, 영적 효과크기에 대한 메타분석 (Meta-Analysis of Spiritual Intervention Studies on Biological, Psychological, and Spiritual Outcomes)

  • 오복자;김영현
    • 대한간호학회지
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    • 제42권6호
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    • pp.833-842
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    • 2012
  • Purpose: The purpose of this study was to evaluate the effectiveness of spiritual intervention studies by examining biological, psychological, and spiritual outcomes. Methods: From electronic databases 2522 studies were retrieved, of which 21 studies met the inclusion criteria. These studies had 1411 participants. Two authors independently extracted data from the selected studies and assessed the methodological quality. The data were analyzed using the RevMan 5.1 program of the Cochrane library. Results: Overall effect size of spiritual intervention on spiritual and psychological (depression and anxiety) outcomes were moderate (d= -0.65 to d= -0.76, p<.001). The effects on biological outcomes (pain and functional status) ranged from -0.51 to -0.39, respectively. No publication bias was detected as evaluated by a funnel plot. Spiritual intervention had a moderate effect on psychological and spiritual outcomes and a smaller effect on biological outcomes. Conclusion: The results of this study suggest that spiritual intervention can relieve depression and anxiety. Further randomized controlled trials studies are needed to evaluate the effects of spiritual intervention on biological outcomes.

Synthesis and Biological Activity of Aspirin Derivatives

  • Cha, Bae-Cheon;Lee, Seung-Bae
    • Archives of Pharmacal Research
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    • 제23권2호
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    • pp.116-120
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    • 2000
  • Aspirin has been widely used as analgesic and anti-inflammatory drug. Recently, it was elucidated that aspirin have anti-coaggregatory effect in low dose. This study was carried out to investigate the synthesis of aspirin derivatives from aspirin and aromatic compound of antioxidant and its biological activities. Synthesis of aspirin derivatives was prepared by esterification in the presence of 1, 1-carbonyldiimidazole. Biological activities was examined using effect of anti-coagulant on bleeding time, effect of antioxidant and effect of anti-platelet aggregation. As a result, SJ-101 showed strong antioxidative activity and anti-coagulant activity among four compounds. Anti-platelet aggregation of SJ-101 was examined by collagen, ADP, PAF method. SJ-101 exhibited more stronger activity to aspirin at collagen aggregation reaction. These finding demonstrates that SJ-101 is usefull as care drug of aging and old-disease because of its has antioxidant activity, anti-coagulant activity and anti-platelet activity.

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생체 카오스의 비선형 시계열 데이터 분석 (Nonlinear Time Series Analysis of Biological Chaos)

  • 이병채;이명호
    • 대한의용생체공학회:의공학회지
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    • 제15권3호
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    • pp.347-354
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    • 1994
  • This paper describes a diagnostic protocol of nonlinear dynamic characteristics of biological system using chaos theory. An integrated chaos analysis system for the diagnosis of biological system was designed. We suggest a procedure of attractor reconstruction for reliable qualitative and quantitative analysis. The effect of autonomic nervous system activity on heart rate variability with power spectral analysis and its characteristics of chaotic attractors are investigated. The results show the applicability to evaluate the mental and physical conditions using nonlinear characteristics of biological signal.

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화장품 소재로써의 딱지꽃(Potentilla chinensis) 뿌리 추출물의 효과 (The Effect of Roots Extract from Potentilla chinensis as Cosmeceutical Material)

  • 유재천;정해수;김형식;이정훈;모상현
    • Journal of Applied Biological Chemistry
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    • 제59권1호
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    • pp.13-17
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    • 2016
  • 천연물을 이용한 산업이 증가됨에 따라 전통약재식물들의 화장품소재로 사용하려는 관심이 높아지고 있다. 다양한 약재식물 중 딱지꽃(Potentilla chinensis) 역시도 다양한 약리 활성이 알려짐에 따라 관심이 높아지고 있다. 그러나 다양한 약리활성을 지닌 반면 딱지꽃(Potentilla chinensis) 을 이용한 산업적 응용은 거의 이루어지지 않고 있다. 본 연구에서는 화장품소재로서의 딱지꽃 뿌리 추출물에 관현 연구를 수행하였다. 그 이유는 딱지꽃의 뿌리 부분이 다른 부분보다 더 많은 약리활성을 지녔다는 보고들이 있었기 때문이다. 딱지꽃 뿌리 추출물을 얻어낸 뒤 항염증, 주름개선, 보습 그리고 미백 효과를 확인함에 따라 딱지꽃 뿌리 추출물을 화장품 소재로 응용가능한지 확인하였다. 그 결과 elastin과 aquaporin-3 증가 효과를 확인할 수 있었고, cyclooxygenase-2, metallopeptidase-1 그리고 melanin 합성 억제효과를 확인할 수 있었다.