• Title/Summary/Keyword: Biofood

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Isolation of Xanthine Oxidase Inhibitors from Ginkgo biloba Leaves-Derived Components

  • Baek, Bong-Rae;Kim, Moo-Key;Lee, Sung-Eun;Hwang, Young-Hee;Lee, Hoi-Seon
    • Preventive Nutrition and Food Science
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    • v.7 no.1
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    • pp.18-21
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    • 2002

  • The extract of Ginkgo biloba leaves was measured for inhibitory activity against xanthine oxidase. Aceton extract of G. biloba leaves showed strong inhibitory activity. Inhibitory activities of the fractionated extract were in the order of water > ethyl acetate fractions. Two fractions exhibiting strong inhibitory activities ware further purified via repeated silica gel, Amberlite IRN-78, Polyclar AT, and Sephadex LH-20 column chromatographies. Active components were isolated and identified through $^1$H-NMR and $^{13}$ C-NMR. The compounds were characterized as kaempferol 3-Ο-$\alpha$-(6$^{"′}$-p-coumaroylglucosyl-$\beta$-1,4-rhamnoside), and quercertin 3-Ο-$\alpha$-(6$^{′}$-p-coumaroylglucosyl-$\beta$-1,4-rhamnoside).

  • https://doi.org/10.3746/jfn.2002.7.1.018 인용 PDF KSCI

Systematic review of the effect of coenzyme Q10 on antioxidant capacity while focused on evaluation of claims for health functional food (건강기능식품의 기능성을 중심으로 한 코엔자임Q10의 항산화 기능성에 대한 체계적 고찰)

  • Kim, Ji Yeon;Jeong, Sewon;Paek, Ju Eun;Kim, Joohee;Kwak, Jin Sook;Lee, Yoon Jung;Kang, Tae Seok;Kwon, Oran
    • Journal of Nutrition and Health
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    • v.46 no.3
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    • pp.218-225
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    • 2013

  • Although the functional ingredient has been evaluated by the Korea Food and Drug Administration (KFDA) based on scientific evidence, the levels of scientific evidence and consistency of the results might vary according to emerging data. Therefore, periodic re-evaluation may be needed for some functional ingredients. In this study, we re-evaluated scientific evidence for the antioxidant activity of coenzyme Q10 as a functional ingredient in health functional food. Literature searches were conducted using the Medline and Cochrane, KISS, and IBIDS databases for the years 1955-2010 with the search term of coenzyme Q10 in combination with antioxidant. The search was limited to human studies published in Korean, English, and Japanese. Using the KFDA's evidence based evaluation system for scientific evaluation of health claims, 33 human studies were identified and reviewed in order to evaluate the strength of the evidence supporting a relation between coenzyme Q10 and antioxidant activity. Among 33 studies, significant effects for antioxidant activities were reported in 22 studies and their daily intake amount was 60 to 300 mg. Based on this systematic review, we concluded that there was possible evidence to support a relation between coenzyme Q10 intake and antioxidant activities. However, because inconsistent results have recently been reported, future studies should be monitored.

  • https://doi.org/10.4163/jnh.2013.46.3.218 인용 PDF KSCI