• Title/Summary/Keyword: Biodynamic

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Review and Evaluation of Hand-Arm Coordinate Systems for Measuring Vibration Exposure, Biodynamic Responses, and Hand Forces

  • Dong, Ren G.;Sinsel, Erik W.;Welcome, Daniel E.;Warren, Christopher;Xu, Xueyan S.;McDowell, Thomas W.;Wu, John Z.
    • Safety and Health at Work
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    • v.6 no.3
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    • pp.159-173
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    • 2015
  • The hand coordinate systems for measuring vibration exposures and biodynamic responses have been standardized, but they are not actually used in many studies. This contradicts the purpose of the standardization. The objectives of this study were to identify the major sources of this problem, and to help define or identify better coordinate systems for the standardization. This study systematically reviewed the principles and definition methods, and evaluated typical hand coordinate systems. This study confirms that, as accelerometers remain the major technology for vibration measurement, it is reasonable to standardize two types of coordinate systems: a tool-based basicentric (BC) system and an anatomically based biodynamic (BD) system. However, these coordinate systems are not well defined in the current standard. Definition of the standard BC system is confusing, and it can be interpreted differently; as a result, it has been inconsistently applied in various standards and studies. The standard hand BD system is defined using the orientation of the third metacarpal bone. It is neither convenient nor defined based on important biological or biodynamic features. This explains why it is rarely used in practice. To resolve these inconsistencies and deficiencies, we proposed a revised method for defining the realistic handle BC system and an alternative method for defining the hand BD system. A fingertip-based BD system for measuring the principal grip force is also proposed based on an important feature of the grip force confirmed in this study.

Intelligent Digital Redesign of Biodynamic Model of HIV-1 (HIV-1 바이오 동역학 모델의 지능형 디지털 재설계)

  • Kim Do-Wan;Joo Young-Hoon;Park Jin-Bae
    • Journal of Institute of Control, Robotics and Systems
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    • v.12 no.6
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    • pp.547-553
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    • 2006
  • This paper studies digital control of biodynamic model of HIV-1 via intelligent digital redesign (IDR). The purpose of the IDR is to develop an equivalent digital fuzzy controller maintaining the satisfactory performance of an existing continuous-time fuzzy controller in the sense of the state-matching. Some conditions for the stability as well as the global state-matching are provided.. They are given by the form of the linear matrix inequalities (LMIs) and thereby easily tractable by the convex optimization techniques. The main features of the proposed method are that 1) the generalized control scheme is provided for the multirate as well as the single-rate digital controllers; 2) a new compensated block-pulse function method is applied to closely match the states of the continuous-time and the sampled-data fuzzy systems in the discrete-time domain; 3) the two-step procedure of IDR is presented to prevent the performance degradation caused by the additional stability conditions. The applicability of the proposed approach is shown through the biodynamic model of HIV-1.

Nonlinearity of Biodynamic Response to Shock-Type Vertical Whole-Body Vibration (쇼크타입 수직방향 전신진동에 대한 생체동역학적 반응의 비선형성)

  • Ahn Se-Jin;Griffin Michael J.;Yoo Wan-Suk;Jeong, Weui-Bong
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.31 no.2 s.257
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    • pp.145-151
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    • 2007
  • Impulsive excitation on vehicle produces shock-type vibration on the seat, which has major frequencies and damping ratios dependent on the characteristics of the suspension, the tire, the seat cushion and so on. The response of single degree of freedom model to a half-sine force input was considered as simple shock-type vibration signal. Quasi-apparent-mass for fifteen subjects was measured with the shock-type vibration generated on a rigid seat mounted on the simulator, so its nonlinearity was apparently found over 6.3 Hz according to the difference of magnitude of the shock.

A Biodynamic Simulation under High Gravity Maneuvering (고중력 가속기동하에서의 생체동역학적 모의실험)

  • Lee, Chang-Min;Park, Sei-Kwon
    • Journal of Korean Institute of Industrial Engineers
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    • v.18 no.2
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    • pp.1-9
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    • 1992
  • The purpose of this paper is to investigate the dynamic situation of the biomechanical responses of a pilot that occur before the black out during high gravity maneuvering. The computer biodynamic simulations using the Articulated Total Body(ATB) model show the following results : 1) the center of gravity(c. g) offsets of a helmet have significant effects on the head deflection angle which is closely connected with the head down : 2) the average and maximum gravity forces are smaller in the curvilinear type of an acceleration than in the straight type of the acceleration, and it is applied to the case of the head deflection angle. We suggest that the new concept of protective device should be necessary to prevent the head down during high gravity maneuvering.

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Facile Synthesis and Biological Evaluation of Heterocyclic Compounds Containing Diazepam

  • Berghot, M.A.
    • Archives of Pharmacal Research
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    • v.24 no.4
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    • pp.263-269
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    • 2001
  • Diazepamoxadiazoles 4,5,6,12,14 and 22 were prepared with the binary form system. Diazepamthiadiazoles 15,20 and Diazepamtriazoles 7,8,9,17,18,19 and 21 were also shapely synthesized. Some of these compounds were screened to test their antibacterial activity against E. coli and B. subtilis compounds 15 and 20 show potent activity against these bacteria.

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Six-axis Biodynamic Response to Vertical Whole-body Vibration (수직방향 진동에 대한 인체의 6축 방향 반응특성분석)

  • Jeon, Gyeoung-Jin;Kim, Min-Seok;Ahn, Se-Jin;Jeong, Weui-Bong;Yoo, Wan-Suk
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2011.04a
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    • pp.218-223
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    • 2011
  • Seated human subjects have been exposed to vertical vibration so as to investigate six-axis biodynamic response. Sixteen males were exposed to random vertical vibration in the frequency range(3~40Hz) at one vibration magnitude(0.224m/$s^2$ r.m.s.). Forces were measured in the vertical, fore-and-aft, lateral, roll, pitch and yaw direction on the seat. The median of cross-axis apparent mass magnitude in the fore-and-aft direction could reach up to 20% of the apparent mass magnitude at resonance frequency. And the median of apparent eccentric mass magnitude in the roll direction could reach up to 15% of the apparent eccentric mass magnitude in the pitch direction at resonance frequency. But cross-axis apparent mass in the lateral direction and apparent eccentric mass in the yaw direction showed very small.

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Experimental Studies on the Preparation of Some $^{99m}Tc$ Instant Labelling Kits (몇가지 $^{99m}Tc$ 즉석표식(卽席標識)킷트 제조(製造)를 위(爲)한 실험연구(實驗硏究))

  • Kim, Jae-Rok;Awh, Ok-Doo;Koo, Hyeon-Sook;Park, Kyung-Bae
    • The Korean Journal of Nuclear Medicine
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    • v.15 no.1
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    • pp.13-20
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    • 1981
  • Using stannous chloride, optimum conditions for $^{99m}Tc$ labelling of some scanning agents such as phytic acid (P A), dimercaptosuccinic acid (DMSA), and calcium diethylenetriaminepentaacetate (Ca-DPTA) were established. Methods of separation and identification of the labelled compounds were practiced by a paper- or thin layer- chromatography. Biodynamic studies of the compounds were also carried out. The results indicate that the molar ratios of the chelating agent and stannous chloride varies only with the concentrations of the chelating agents, and thus the amounts of the stannous chloride per labelling tube were nearly constant $(500\sim600{\mu}g)$ regardless the variation of the molar ratios. It suggests that the given experimental conditions require about $500{\mu}g$ of stannous chloride regardless of the chelating agents. Under alkaline pH, the labelling yields were drastically decreased due to the probable formation of colloidal tin compounds. Biodynamic data showed characteristic patterns with each compound indicating that they are all suitable for the relevant scanning applications.

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Microbiological Features and Bioactivity of a Fermented Manure Product (Preparation 500) Used in Biodynamic Agriculture

  • Giannattasio, Matteo;Vendramin, Elena;Fornasier, Flavio;Alberghini, Sara;Zanardo, Marina;Stellin, Fabio;Concheri, Giuseppe;Stevanato, Piergiorgio;Ertani, Andrea;Nardi, Serenella;Rizzi, Valeria;Piffanelli, Pietro;Spaccini, Riccardo;Mazzei, Pierluigi;Piccolo, Alessandro;Squartini, Andrea
    • Journal of Microbiology and Biotechnology
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    • v.23 no.5
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    • pp.644-651
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    • 2013
  • The fermented manure derivative known as Preparation 500 is traditionally used as a field spray in biodynamic agriculture for maintaining and increasing soil fertility. This work aimed at characterizing the product from a microbiological standpoint and at assaying its bioactive properties. The approach involved molecular taxonomical characterization of the culturable microbial community; ARISA fingerprints of the total bacteria and fungal communities; chemical elemental macronutrient analysis via a combustion analyzer; activity assays for six key enzymes; bioassays for bacterial quorum sensing and chitolipooligosaccharide production; and plant hormone-like activity. The material was found to harbor a bacterial community of $2.38{\times}10^8$ CFU/g dw dominated by Gram-positives with minor instances of Actinobacteria and Gammaproteobacteria. ARISA showed a coherence of bacterial assemblages in different preparation lots of the same year in spite of geographic origin. Enzymatic activities showed elevated values of ${\beta}$-glucosidase, alkaline phosphatase, chitinase, and esterase. The preparation had no quorum sensing-detectable signal, and no rhizobial nod gene-inducing properties, but displayed a strong auxin-like effect on plants. Enzymatic analyses indicated a bioactive potential in the fertility and nutrient cycling contexts. The IAA activity and microbial degradation products qualify for a possible activity as soil biostimulants. Quantitative details and possible modes of action are discussed.