• Title/Summary/Keyword: Biochemical indices

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Relationships Between Dietary Behavior and Serum Lipids of Health Examinees at General Hospitals in Busan (부산지역 건강검진 수검자의 식행태와 혈청 지질과의 관계)

  • Son, Eun-Joo;Lyu, Eun-Soon
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.42 no.1
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    • pp.46-52
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    • 2013
  • The purpose of this study was to measure the serum lipid concentrations by gender and age, and to investigate the relationship between dietary behavior and serum lipid levels in Korean adults. The subjects consisted of 209 volunteers (121 men and 88 women) who visited a health promotion center. Their anthropometric and biochemical blood indices were measured, and data on lifestyles were obtained using structured questionnaires. The blood total cholesterol, LDL-cholesterol, and triglyceride concentrations increased significantly with age in women (p<0.01). The food habit score of men and women increased with age, and total food habit score was negatively correlated with BMI (p<0.05). The rate of skipping meals (p<0.001), overeating (p<0.05), eating instant food (p<0.001), and eating out (p<0.05) decreased significantly with age, and the intake rate of vegetables (p<0.001) and carbohydrates (p<0.05) significantly increased with it. The food intake frequency of 21 food items was also measured, and snacks (p<0.05), high fat foods (p<0.01) meats (p<0.05), and instant foods (p<0.01) were negatively correlated with HDL-cholesterol. Snacks (p<0.05) and high fat foods (p<0.01) were positively correlated with LDL-cholesterol. Snacks (p<0.05) and fats/oils (p<0.01) were positively correlated with triglycerides. These results suggest that the food habits and food intake frequency may be one of the important factors affecting serum lipid concentrations in Korean adults.

Comparison for immunophysiological responses of Jeju and Thoroughbred horses after exercise

  • Khummuang, Saichit;Lee, Hyo Gun;Joo, Sang Seok;Park, Jeong-Woong;Choi, Jae-Young;Oh, Jin Hyeog;Kim, Kyoung Hwan;Youn, Hyun-Hee;Kim, Myunghoo;Cho, Byung-Wook
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.3
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    • pp.424-435
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    • 2020
  • Objective: The study was conducted to investigate variations in the immunophysiological responses to exercise-induced stress in Jeju and Thoroughbred horses. Methods: Blood samples were collected from the jugular veins of adult Jeju (n = 5) and Thoroughbred (n = 5) horses before and after 30 min of exercise. The hematological, biochemical, and immunological profiles of the blood samples were analyzed. Blood smears were stained and observed under a microscope. The concentration of cell-free (cf) DNA in the plasma was determined using real time polymerase chain reaction (PCR). Peripheral blood mononuclear cells (PBMCs) and polymorphonuclear cells were separated using Polymorphprep, and the expression of various stress-related and chemokine receptor genes was measured using reverse transcriptase (RT) and real-time PCR. Results: After exercise, Jeju and Thoroughbred horses displayed stress responses with significantly increased rectal temperatures, cortisol levels, and muscle catabolism-associated metabolites. Red blood cell indices were significantly higher in Thoroughbred horses than in Jeju horses after exercise. In addition, exercise-induced stress triggered the formation of neutrophil extracellular traps (NETs) and reduced platelet counts in Jeju horses but not in Thoroughbred horses. Heat shock protein 72 and heat shock protein family A (Hsp70) member 6 expression is rapidly modulated in response to exercise-induced stress in the PBMCs of Jeju horses. The expression of CXC chemokine receptor 4 in PBMCs was higher in Thoroughbred horses than in Jeju horses after exercise. Conclusion: In summary, the different immunophysiological responses of Jeju and Thoroughbred horses explain the differences in the physiological and anatomical properties of the two breeds. The physiology of Thoroughbred horses makes them suitable for racing as they are less sensitive to exercise-induced stress compared to that of Jeju horses. This study provides a basis for investigating the link between exercise-induced stresses and the physiological alteration of horses. Hence, our findings show that some of assessed parameters could be used to determine the endurance performance of horses.

Evaluation of factors affecting sensory neural hearing loss (감각신경성 청력손실에 영향을 미치는 제 요인에 관한 연구)

  • Hong, Seong-Chul;Bae, Seong-Wook;Lee, Jong-Young
    • Journal of Preventive Medicine and Public Health
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    • v.31 no.2 s.61
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    • pp.249-264
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    • 1998
  • Reports on a potential relationship between sensory neural hearing loss(SNHL) and cardiovascular or hematologic factor show that the results are controversial. A detailed analysis of risk factors in the development of SNHL was carried out in 3,050 non-noise exposed healthy worker. The mean hearing threshold of both ears at 500, 1000, 2000, 4000, 8000Hz was measured and the effect of age, possible cardiovascular risk factor and hematologic factor (blood viscosity and hemostatic factors) on SNHL were evaluated. first, each of these were associated with loss of hearing sensitivity when univariately and multivariatively analysed. In a multiple regression model, age, sex, body mass index, WBC and total cholesterol level were independently associated with the mean of hearing sensitivity decrease at 4000 and 8000Hz. Second, study subjects were divided into two group (normal vs SNHL) and we compare the possible risk between both groups, and analysed univariate and multivariative logistic model. In a multiple logistic regression model, age, sex, body mass index, WBC and total cholesterol level, total protein, platelet were independently associated with SNHL. Our results show that we have some reliable indices of susceptibility to SNHL using cardiovascular measures or biochemical factor, but future, more extensive studies are required.

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Effects of Heat-oxidized Soy Protein Isolate on Growth Performance and Digestive Function of Broiler Chickens at Early Age

  • Chen, X.;Chen, Y.P.;Wu, D.W.;Wen, C.;Zhou, Y.M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.28 no.4
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    • pp.544-550
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    • 2015
  • This study was conducted to investigate effects of heat-oxidized soy protein isolate (HSPI) on growth performance, serum biochemical indices, apparent nutrient digestibility and digestive function of broiler chickens. A total of 320 1-day-old Arbor Acres chicks were randomly divided into 4 groups with 8 replicates of 10 birds, receiving diets containing soy protein isolate (SPI, control group) or the same amount of SPI heated in an oven at $100^{\circ}C$ for 1, 4, or 8 h, for 21 days, respectively. The results indicated that compared with the control group, body weight gain and feed intake of birds fed diet containing SPI heated for 8 h were significantly lower (p<0.05). Serum urea nitrogen concentration was higher in the broilers fed diet containing SPI heated for 4 or 8 h at d 21 (p<0.05). In contrast, serum glucose content was decreased by HSPI substitution at d 21 (p<0.05). The relative pancreas weight in HSPI groups was higher than that in the control group at d 21 (p<0.05). Meanwhile, the opposite effect was observed for relative weight of anterior intestine and ileum in broilers fed a diet containing SPI heated for 8 h (p<0.05). Birds fed diets containing SPI heated for 4 or 8 h had a decreased lipase activity in anterior intestinal content at d 14 and 21 (p<0.05), respectively. In addition, the same effect was also noted in broilers given diets containing SPI heated for 1 h at d 21 (p<0.05). Similarly, amylase, protease and trypsin activity in anterior intestinal content were lower in broilers fed diets containing SPI heated for 8 h at d 21 (p<0.05). The apparent digestibility of dry matter (DM) from d 8 to 10 and DM, crude protein (CP), and ether extract from d 15 to 17 were lower in broilers fed diets containing SPI heated for 8 h (p<0.05). Besides, birds given diets containing SPI heated for 4 h also exhibited lower CP apparent digestibility from d 15 to 17 (p<0.05). It was concluded that HSPI inclusion can exert a negative influence on the growth performance of broilers, which was likely to result from the simultaneously compromised digestive function.

Development of morning bread fortified citrus peels powders and its evaluation of biological activity by human trial (귤피가루를 첨가한 모닝빵 개발 및 인체시험을 통한 생리활성 효과 평가)

  • Lee, Ha-Neul;Park, Tae-Sun;Yu, Ok-Kyeong;Byun, Moon-Sun;Cha, Youn-Soo
    • Journal of Nutrition and Health
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    • v.49 no.3
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    • pp.144-152
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    • 2016
  • Purpose: This study was conducted in order to develop morning bread using powdered citrus peels and to examine the effect of its several biological activities for 12 weeks in overweight adults ($$BMI{\geq_-}23$$) living in dormitories of Chonbuk National University. Methods: Control bread was prepared using the same formula except for replacing the wheat flour with 3% citrus peel powder. Subjects were classified according to two groups: Intake group of 3% citrus peel powder fortified morning bread (n = 30) and general morning bread (n = 30). Results: The results of our study showed no significant effects of citrus peel powdered morning bread on anthropometric indices and biochemical characteristics among overweight adults. Despite the slight reduction in total-cholesterol, LDL-cholesterol, GOT, and GPT (p < 0.05), no significant differences in changes of these values were observed between the two groups. Conclusion: The short duration of our intervention might have resulted in the lack of any significant effect. Therefore, conduct of further studies with longer duration is warranted in order that the results from this study can be utilized as a basis for the development of food products with citrus peel powder.

A Study on the Nutrient Intakes and Zinc Nutritional Status of Preschool Children in Ulsan (울산지역 유치원 어린이의 <한국인영양섭취기준>에 의한 영양소섭취 실태 및 아연영양 상태에 관한 연구)

  • Yu, Kyeong-Hee
    • Journal of Nutrition and Health
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    • v.40 no.4
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    • pp.385-394
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    • 2007
  • The purpose of this study was to determine the zinc status of preschool children in Ulsan. The study was conducted in 95 children aged 3 to 6 years by investigating the anthropometric indices and assessing the biochemical analysis. The blood was analysed to assess serum zinc and alkaline phosphatase. And a questionnaire for dietary intakes using 24-hr recall method were performed by mothers of 95 subjects. The dietary intakes of children were analysed to determine the prevalence of inadequate and excessive intakes of zinc with Dietary Reference Intakes for Koreans (KDRIs). WHL (Weight-Length Index) and Kaup index were used to define obesity. The overall prevalence of overweight and obese subjects were 14.7% and 6.3% by WHL, were 15.8% and 13.7% by Kaup index. The mean intakes of zinc by children aged 3${\sim}$5y and 6y were 5.5 ${\pm}$ 1.4 mg/d (75.7% RDA) and 6.7 ${\pm}$ 2.0 mg/d, respectively, that was the level exceeding the estimated average requirement (EAR) and the recommended intake (RI) of Korean Dietary Reference Intakes. Less than 1.3% and 7.9% of children had usual zinc intakes below EAR and RI of KDRIs, respectively. The percentages of children with intakes exceeding the tolerable upper intake level (UL) were 2.6%. The zinc nutritional status by biological assay was found that mean serum zinc and alkaline phosphatase (ALP) of total subjects were 64.0 ${\pm}$ 8.4 ${\mu}$g/dl and 72.8 ${\pm}$ 14.9 U/L, there was not a significant difference between boys and girls. The range of serum zinc level was 45${\sim}$89 ${\mu}$g/dl and children with a low serum zinc concentration by several cut-off points were 18.9${\sim}$55.8%, especially. Serum zinc level was positively correlated to the intakes of calorie, calcium, fiber, iron, zinc, zinc/kg and height (p<0.001). Serum ALP was positively correlated height, weight and WLI. The zinc intake of children aiso showed a positive correlation with height and weight. These results indicate that there were significant correlations between the zinc status and growth of preschool children. Preschool children in Ulsan have dietary zinc intakes that exceed the new DRIs. The present level of intake does not seem to pose a health problem, but if zinc intakes with fortified foods and supplements were considered, the amount of zinc consumed by children may become excessive.

Impact Assessment of Sewage Effluent on Freshwater Crucian Carp Carassius auratus using Biochemical and Histopathological Biomarkers (생화학적 및 조직병리학적 생체지표를 이용한 하수처리장 방류수의 담수 붕어(Carassius auratus) 영향 평가)

  • Samanta, Palas;Im, Hyungjoon;Lee, Hwanggoo;Hwang, Soon-Jin;Kim, Wonky;Ghosh, Apurba Ratan;Jung, Jinho
    • Journal of Korean Society on Water Environment
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    • v.32 no.5
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    • pp.419-432
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    • 2016
  • The aim of this study is to assess the influence of effluent discharge from a sewage treatment plant by evaluating oxidative stress and histopathological alterations in freshwater crucian carp Carassius auratus collected from the Eungcheon stream, located in Korea. Catalase activity in the gills, liver, and kidneys of C. auratus was collected from mixing zones; the downstream site was notably higher of fish than that of the upstream site. In addition, the activity of glutathione-S-transferase in the gills and liver was significantly higher in samples from the mixing zone than in those from the upstream site (p < 0.05). In addition, significantly elevated lipid peroxidation levels were observed in fish livers sampled from the mixing zone than in those from the upstream site (p < 0.05). Significant histopathological alternations were also observed in C. auratus, with the order of magnitude changes being liver > kidney > gills. These findings suggest that the liver is most affected by effluent discharge. The degree of tissue changes (DTC) indicate that the highest level occurred in samples from the mixing zone (30.98 ± 5.40) followed by those from the downstream site (19.28 ± 4.31) and was the lowest in samples from the upstream site (4.83 ± 2.67). These findings indicate that fish collected from the mixing zone are most affected by effluent discharge and both oxidative stress and histopathological indices are useful tools for monitoring contaminated rivers and streams.

A Study on Urinary N-acetyl-$\beta$-D-glucosaminidase Activities of Office Workers in a Certain Industrial Complex Area (모 공단지역 사무직 근로자들의 요중 N-acetyl-$\beta$-D-glucosaminidase 역가에 관한 연구)

  • Kim, Hwa-Sung;Lee, Gap-Soo;Lee, Sung-Soo;Ahn, Kyu-Dong;Lee, Byung-Kook
    • Journal of Preventive Medicine and Public Health
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    • v.27 no.3 s.47
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    • pp.547-556
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    • 1994
  • In order to identify the necessary information of biochemical Indices for renal effect of lead for the early detection in medical surveillance of lead worker, the reference values of urinary N-acetyl-$\beta$-D-glucosaminidase (NAG) activities were studied with 205 office workers in one industrial complex area who were not exposed to lead occupationally. While study variables selected for lead exposure were blood lead (PbB), blood zinc protoporphyrin(ZPP) and $\delta$-aminolevulinic acid (DALA) in urine, those for renal effect were urinary N-acetyl-$\beta$-D-glucosaminidase (NAG), blood urea nitrogen (BUN), serum creatinine(Cr), serum uric acid (Ua), and urinary total protein(U-TP). The results obtained were as follows: 1. The mean values of blood lead, ZPP and DALA in all subjects were $14.39{\pm}4.02{\mu}g/dl,\;21.61{\pm}8.00{\mu}g/dl,\;and\;2.73{\pm}0.90mg/l$ respectively. 2. The mean value of urinary NAG activities in all subjects was $3.51{\pm}2.01U/l$. The mean value of urinary NAG activities, which calculated from NAG activities divided by urinary creatinine concentration (CNAG), was $5.42{\pm}5.53U/g$ creatinine and log-arithmic normal distributed. 3. The reference value of urinary NAG activity was 12.06 U/g creatinine(95% CU=10.57-14.76 U/g creatinine). 4. Logarithmic CNAG(r=0.781 p<0.0l), U-TP(r=0.670 p<0.01) and ZPP(r=0.172 p<0.05) showed statistically significant correlation with CNAG.

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Probabilistic assessment of causal relationship between drought and water quality management in the Nakdong River basin using the Bayesian network model (베이지안 네트워크 모형을 이용한 낙동강 유역의 가뭄과 수질관리의 인과관계에 대한 확률론적 평가)

  • Yoo, Jiyoung;Ryu, Jae-Hee;Lee, Joo-Heon;Kim, Tae-Woong
    • Journal of Korea Water Resources Association
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    • v.54 no.10
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    • pp.769-777
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    • 2021
  • This study investigated the change of the achievement rate of the target water quality conditioned on the occurrence of severe drought, to assess the effects of meteorological drought on the water quality management in the Nakdong River basin. Using three drought indices with difference time scales such as 30-, 60-, 90-day, i.e., SPI30, SPI60, SPI90, and three water quality indicators such as biochemical oxygen demand (BOD), total organic carbon (TOC), and total phosphorus (T-P), we first analyzed the relationship between severe drought occurrence water quality change in mid-sized watersheds, and identified the watersheds in which water quality was highly affected by severe drought. The Bayesian network models were constructed for the watersheds to probabilistically assess the relationship between severe drought and water quality management. Among 22 mid-sized watersheds in the Nakdong River basin, four watersheds, such as #2005, #2018, #2021, and #2022, had high environmental vulnerability to severe drought. In addition, severe drought affected spring and fall water quality in the watershed #2021, summer water quality in the #2005, and winter water quality in the #2022. The causal relationship between drought and water quality management is usufaul in proactive drought management.

Effect of Perch Material Type on Performance, Blood Characteristics, and Feather Score of Layer Pullets on Floor during Growth Period (산란계 평사 사육시 육성기 홰 재질에 따른 생산성, 혈액성상, 깃털 손상도에 미치는 영향)

  • Kim, Hee-Jin;Son, Jiseon;Hong, Eui-Chul;Kang, Hwan Ku
    • Korean Journal of Organic Agriculture
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    • v.29 no.4
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    • pp.589-600
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    • 2021
  • The present study investigated the effect of perch material type (wood and steel) on performance, blood characteristics, and feather pecking. A total of 1,700, one-day-old female Hy-Line brown chicks were evenly assigned to two treatments (wood and steel). The body weight and uniformity of birds were investigated over a 10-week experimental period. Blood characteristics and feather pecking was conducted at week 10. The wood perch treatment (WP) and steel perch treatment (SP) did not differ in their body weight, uniformity, and serum biochemical profile (except inorganic phosphorus) of pullets. Inorganic phosphorus on serum in WP significantly higher than that in SP (P<0.05). Blood corpuscle composition (leukocyte, erythrocyte, and Heterophil / Lymphocyte ratio) of pullets did not show any significant differences among treatments at week 10. Serum corticosterone and feather score that is stress and welfare indices were not affected by the type of perch material. In conclusion, our results suggest that performance, blood characteristics, and feather pecking of pullets were not affected by the perch material type. The results of this study can serve as basic data for investigating the effects of perch type on layer pullets.