• Title/Summary/Keyword: BioSIM

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Growth retardants stimulate guggulsterone production in the presence of fungal elicitor in fed-batch cultures of Commiphora wightii

  • Suthar, Satish;Ramawat, K.G.
    • Plant Biotechnology Reports
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    • v.4 no.1
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    • pp.9-13
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    • 2010
  • Guggulsterone, a hypolipidemic natural agent, is produced in resin canals of the plant Commiphora wightii. In this study, the stimulatory effects of growth retardants [ALAR (N,N-dimethylaminosuccinamic acid) and CCC (chlormequat chloride)] and fungal elicitor on guggulsterone accumulation in cell cultures of C. wightii are reported. CCC at $1\;mg\;l^{-1}$ enhanced guggulsterone content (${\sim}123\;{\mu}g\;l^{-1})$ when added on the fifth day after inoculation, while ALAR at $2.5\;{\mu}g\;l^{-1}$ increased guggulsterone content (${\sim}116\;{\mu}g\;l^{-1}$) when added on the tenth day. In a two-stage fed-batch process, combined treatment with fungal elicitor and growth retardant caused a significant increase (${\sim}353\;{\mu}g\;l^{-1}$) in guggulsterone content in cell cultures after 17 days of growth. This represents an approximately fivefold increase over the guggulsterone contents in initial cultures of this plant.

Development of Temperature Control Technology of Root Zone using Evaporative Cooling Methods in the Strawberry Hydroponics (증발 냉각방식을 이용한 딸기 수경재배의 배지 온도조절 기술 개발)

  • Kim, Ki-Dong;Ha, Yu-Shin;Lee, Ki-Myung;Park, Dae-Heum;Kwon, Soon-Gu;Park, Jong-Min;Chung, Sung-Won
    • Journal of Bio-Environment Control
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    • v.19 no.4
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    • pp.183-188
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    • 2010
  • It is necessary to develop an efficient and affordable cooling technology and apply the practical system to rural farmhouse, control to adequate growth environment by adjusting temperature of root zone. A study on managing medium temperature of the hydroponics for strawberry cultivation was conducted and feasible evaporative cooling system for the media cooling were as follows: Characteristics of temperature drop were investigated for the evaporative cooling devices using microporous film duct, felt mulching on media surface, and water permeable sheet in culture tank. The evaporative device with water permeable sheet in culture tank was the most efficient and economic on media cooling system.

Development a glucose-FIA system with a fiber optic oxygen sensor

  • Sohn, Ok-Jae;Lam, Tuan-Hung;Rhee, Jong-Il
    • 한국생물공학회:학술대회논문집
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    • 2005.10a
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    • pp.730-734
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    • 2005
  • Flow injection analysis (FIA) system was developed to monitor glucose concentrations in biotechnological processes. A fiber optic oxygen sensor was used to determine consumption of oxygen concentration by reaction of immobilized glucose oxidase (GOD). The GOD was immobilized on VA-Epoxy carrier and integrated into FIA system. A calibration curve for glucose was obtained in the range of 0.5 $g/L{\sim}3.0$ g/L.

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Design of Clustering CoaT Vision Model Based on Transformer (Transformer 기반의 Clustering CoaT 모델 설계)

  • Bang, Ji-Hyeon;Park, Jun;Jung, Se-Hoon;Sim, Chun-Bo
    • Annual Conference of KIPS
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    • 2022.05a
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    • pp.546-548
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    • 2022
  • 최근 컴퓨터 비전 분야에서 Transformer를 도입한 연구가 활발히 연구되고 있다. 이 모델들은 Transformer의 구조를 거의 그대로 사용하기 때문에 확장성이 좋으며 large 스케일 학습에서 매우 우수한 성능을 보여주었다. 하지만 Transformer를 적용한 비전 모델은 inductive bias의 부족으로 학습 시 많은 데이터와 시간을 필요로 하였다. 그로 인하여 현재 많은 Vision Transformer 개선 모델들이 연구되고 있다. 본 논문에서도 Vision Transformer의 문제점을 개선한 Clustering CoaT 모델을 제안한다.

Design and Implementation of HRNet Model Combined with Spatial Information Attention Module of Polarized Self-attention (편광 셀프어텐션의 공간정보 강조 모듈을 결합한 HRNet 모델 설계 및 구현)

  • Jin-Seong Kim;Jun Park;Se-Hoon Jung;Chun-Bo Sim
    • Annual Conference of KIPS
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    • 2023.05a
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    • pp.485-487
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    • 2023
  • 컴퓨터 비전의 하위 태스크(Task)인 의미론적 분할(Semantic Segmentation)은 자율주행, 해상에서 선박찾기 등 다양한 분야에서 연구되고 있다. 기존 FCN(Fully Conovlutional Networks) 기반 의미론적 분할 모델은 다운샘플링(Dowsnsampling)과정에서 공간정보의 손실이 발생하여 정확도가 하락했다. 본 논문에서는 공간정보 손실을 완화하고자 PSA(Polarized Self-attention)의 공간정보 강조 모듈을 HRNet(High-resolution Networks)의 합성곱 블록 사이에 추가한다. 실험결과 파라미터는 3.1M, GFLOPs는 3.2G 증가했으나 mIoU는 0.26% 증가했다. 공간정보가 의미론적 분할 정확도에 영향이 미치는 것을 확인했다.

Effects of artificial water treatment on the growth and leaf characteristics of Fraxinus rhynchophylla and Fraxinus mandshurica (인위적인 수분처리가 물푸레나무와 들메나무의 생장과 엽형특성에 미치는 영향)

  • Chung, Jin-Chul;Choi, Jeong-Ho;Park, Kyong-Woo;Yoo, Se-Kuel;Lee, Soo-Won;Bae, Jong-Hyang
    • Journal of Bio-Environment Control
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    • v.16 no.2
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    • pp.135-141
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    • 2007
  • Although the result of the tree height growth after water treatment, Fraxinus rhynchophylla has little affection by the artificial water treatment, the growth showed decreased tendency as the soil moisture decreased, and F. mandshurica showed high growth in relatively high soil moist $78{\sim}90%$ treated area. The growth of root collar diameter of F. rhynchophylla and F. mandshurica also showed decreased tendency as soil moisture decreased. The changes of biomass according to dry weight of root, stem, leaves of F. rhynchophylla demonstrating statistical significance as moisture contents of soil is lower showing decreased biomass tendency and in the treatment of $78{\sim}90%$(A) moisture content showed more than double the higher biomass compare to the treated area of $18{\sim}30%$(D) moisture contents. Also F. mandshurica showed statistical significance in A and D treatment demonstrating differences among each treatment. This can be purported to have physiological effects like weakening of seedling and softening of tissues including leaves as soil moisture decreased. Ultimately it is regarded to the main reason of unsatisfactory growth for F. rhynchophylla and F. mandshurica that are weak to drought resistance. SLA, which is one of the special traits of leaf area of F. rhynchophylla, didn't show statistical significance between moisture process, it demonstrated decreased tendency as the moisture content interval is minimal. LAR and LWR showed increased tendency while moisture content didn't show statistical significance between treatments as they are minimal.

Periodically domain inversion and optical properties of low-loss Ti : $LiNbO_3$ waveguides (저손실 Ti : $LiNbO_3$ 광도파로의 주기적 분극 반전과 광학특성)

  • Yang, W.S.;Kwon, S.W.;Lee, H.M.;Kim, W.K.;Yoon, D.H.;Lee, H.Y.
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.16 no.2
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    • pp.49-52
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    • 2006
  • Periodic electric field assisted poling low loss (${\sim}0.1dB/cm$) single-mode Ti-diffused waveguides in $LiNbO_3$ has been achieved using a periodically patterned electrode on the +Z surface of Ti : $LiNbO_3$ crystal and homogeneous LiCl solution. Using selective chemical etching, we confirmed the periodic (${\sim}16{\mu}m$) domain inverted structure and measured SH (second harmonic) properties of fabricated periodically poled Ti : $LiNbO_3$ waveguides.

Bioequivalence of GomcillinTM Capsule to FamoxinTM Capsule (Amoxicillin 500 mg) (파목신 캅셀(아목시실린 500 mg)에 대한 곰실린 캅셀의 생물학적동등성)

  • Lee, Yun-Young;Choi, Mee-Hee;Lee, Kyung-Ryul;Lee, Hee-Joo
    • Journal of Pharmaceutical Investigation
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    • v.34 no.4
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    • pp.311-317
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    • 2004
  • A bioequivalence study of $Gomcillin^{TM}$ capsules (DAEWOONG Pharmaceutical Co., Korea) to $Famoxin^{TM}$ capsules (Dong Wha Pharm. Ind. Co., Korea) was conducted according to the guideline of Korea Food and Drug Administration (KFDA). Twenty four healthy male Korean volunteers received each medicine at the amoxicillin dose of 500 mg in a $2{\times}2$ crossover study. There was a one-week wash out period between the doses. Plasma concentrations of amoxicillin were monitored by a high-performance liquid chromatography for over a period of 8 hours after the administration. $AUC_t$ (the area under the plasma concentration-time curve from time zero to 8 hr) was calculated by the linear trapezoidal rule method. $C_{max}$ (maximum plasma drug concentration) and $T_{max}$ (time to reach $C_{max}$) were compiled from the plasma concentration-time data. Analysis of variance was carried out using logarithmically transformed $AUC_t$ and $C_{max}$. No significant sequence effect was found for all of the bioavailability parameters indicating that the crossover design was properly performed. The 90% confidence intervals of the $AUC_t$ ratio and the $C_{max}$ ratio for $Gomcillin^{TM}/Famoxin^{TM}$ were $log0.91\;{\sim}\;log1.03$ and $;log0.93\;{\sim}\;log1.10$, respectively. These values were within the acceptable bioequivalence intervals of $log0.80\;{\sim}\;log1.25$. Thus, our study demonstrated the bioequivalence of $Gomcillin^{TM}$ and $Famoxin^{TM}$ with respect to the rate and extent of absorption.

Maxillary sinus floor augmentation with anorganic bovine bone : Histologic evaluation in humans (Anorganic bovine bone을 이용한 상악동저 거상술의 조직학적 평가)

  • Son, Woo-Kyung;Shin, Seung-Yun;Yang, Seung-Min;Kye, Seung-Beom
    • Journal of Periodontal and Implant Science
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    • v.39 no.1
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    • pp.95-102
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    • 2009
  • Purpose: The aim of this report is to investigate the efficacy of anorganic bovine bone xenograft(Bio-$Oss^{(R)}$) at maxillary sinus floor augmentation. Materials and methods: Two male patients who missed maxillary posterior teeth were included. They were performed maxillary sinus floor augmentation using anorganic bovine bone xenograft(Bio-$Oss^{(R)}$). After 10 or 13 months, the regenerated tissues were harvested using trephine drills with 2 or 4mm diameter and non-decalcified specimens were made. The specimens were examined histologically and histomorphometrically to investigate graft resorption and new bone formation. Results: Newly formed bone was in contact with Bio-$Oss^{(R)}$ particles directly without any gap between the bone and the particles. The proportions of newly formed bone were $23.4{\sim}25.3%$ in patient 1(Pt.1) and 28.8% in patient 2(Pt.2). And the proportions of remained Bio-$Oss^{(R)}$ were $29.7{\sim}30.2%$ in Pt.1 and 29.2% in Pt.2. The fixtures installed at augmented area showed good stability and the augmented bone height was maintained well. Conclusion: Anorganic bovine bone xenograft(Bio-$Oss^{(R)}$) has high osteoconductivity and helps new bone formation, so that it can be used in maxillary sinus floor augmentation.

Advanced Treatment Efficiency of Biological String Media and Oenanthe javanica for Effluent Quality Improvement in the Sedimentation Model Plant (하수의 최종 유출수 수질 개선을 위한 침전조 모형실험에 적용한 끈상 미생물접촉재와 미나리의 고도처리효율에 관한 연구)

  • Bae Joon-Sam;Lee Sang-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.7 no.3
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    • pp.440-447
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    • 2006
  • This study was aimed at the improvement of the effluent quality of municipal wastewater treatment plant by Oenanthe javanica and Bio-string media. The results were compared with conventional sedimentation tank and pilot sedimentation plant. In this study BOD as organic pollutants, SS, Nitrogen and Phosphorus were tested to evaluate the removal efficiencies for the advanced treatment. The result were as follow: in the Pilot Plant experiment, Tank 2 was fairly high removal efficiency as compared with Tank 1. The removal efficiency of BOD and SS in Tank 2 were as a range of $7.9%{\sim}38.8%,\;14.3%{\sim}60.0%$ and the removal efficiency of T-N, T-P were a range of $9.6%{\sim}31.5%,\;33.0%{\sim}80.0%$ respectively. The removal efficiency of T-P and SS were much higher than BOB and T-N.

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