• Title/Summary/Keyword: Bio-block

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Effect of Polymer Wrapping on the Properties of ABS/MWNT Nanocomposites (고분자 래핑(wrapping)에 의한 전처리가 ABS/MWNT 나노복합체의 물성에 미치는 영향)

  • Kim, Jung-Hwan;Min, Byung-Gil
    • Textile Coloration and Finishing
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    • v.22 no.1
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    • pp.37-42
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    • 2010
  • ABS/MWNT nanocomposites were prepared by using MWNT wrapped with SAN through melt compounding. Effect of wrapping of MWNT by SAN on the morphology, mechanical and electrical properties of ABS/MWNT were analyzed. It was found that SAN could wrap MWNT effectively indicated by the increased thickness after wrapping, which is presumably due to helical structure of polyacrylonitrile component in a block copolymer of SAN. MWNT was observed to be dispersed more evenly in ABS matrix by SAN wrapping, which resulted in improved tensile properties of the composites. On the other hand, there was little effect on the impact strength and electrical properties of ABS having inherently high impact strength.

Non-glasses Stereoscopic 3D Floating Hologram System using Polarization Technique

  • Choi, Pyeongho;Choi, Yoonhee;Park, Misoo;Kwon, Soonchul;Lee, Seunghyun
    • International journal of advanced smart convergence
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    • v.8 no.1
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    • pp.18-23
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    • 2019
  • The image projected onto the screen of the floating hologram is no more than a two-dimensional image. Although it creates an illusion that an object appears to float in space as it moves around while showing its different parts. This paper has proposed a novel method of floating 3D hologram display to view stereoscopic three-dimensional images without putting on glasses. The system is comprised of a sharkstooth scrim screen, projector, polarizing filter for the projector, and a polarizing film to block the image projected from the sham screen. As part of the polarization characteristics, the background image and the front object have completely been separated from each other with the stereoscopic 3D effect successfully implemented by the binocular disparity caused by the distance between the two screens.

Interaction between odontoblast and bio-calcium phosphate cement reinforced with chitosan (치아모세포와 키토산으로 강화된 생체 적합 칼슘인산시멘트와의 상호작용)

  • Chun, Byung-Do;Kim, Sung-Won;Lee, Sung-Tak;Kim, Tae-Hoon;Lee, Jung-Han;Kim, Gyoo-Cheon;Kim, Yong-Deok;Kim, Uk-Kyu
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.37 no.5
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    • pp.415-420
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    • 2011
  • Purpose: Calcium phosphate cement (CPC) is one of many useful materials for restoring tooth defects, periodontium and maxillofacial area. Chitosan is a biodegradable material that has been shown to promote the growth and differentiation of osteoblasts in culture. This study examined the interaction between odontoblasts and bio-calcium phosphate cement reinforced with chitosan. Materials and Methods: $5{\times}10^3$ odontoblastic cells were seeded into each well. Various concentrations of bio-calcium phosphate cement reinforced with chitosan (10, 20, 50, 100, 200, 500 ${\mu}g$/ml, 1, 2, 4 mg/ml) were diluted and added to the wells. The well was incubated for 24 h, 48 h and 72 h. After incubation, the number of cells was assessed to determine the cell viability. A cytokinesis-block micronucleus assay and chromosomal aberration test were carried out to estimate the extent of chromosomal abnormalities. Microscopic photographs and RT-PCR were performed to examine the adhesion potential of bio-calcium phosphate cement reinforced with chitosan. Results: Bio-CPC-reinforced chitosan did not show significant cytotoxicity. The number of damaged chromosomes in the cells treated with Bio-CPC-reinforced chitosan was similar to that in the control cells. There was no significant increase in the number of chromosomal aberrations in the Bio-CPC reinforced chitosan exposed cells. Microscopic photographs and RT-PCR confirmed the adhesive potential of bio-CPC reinforced chitosan to odontoblasts. Conclusion: Bio-CPC-reinforced chitosan did not affect the odontoblastic cell viability, and had no significant cytotoxic effect. Bio-CPC-reinforced chitosan showed adhesive potential to odontoblasts. These results are expected form the basis of future studies on the effectiveness of dental restorative materials in Bio-CPC reinforced with chitosan.

Discovering the anti-cancer phytochemical rutin against breast cancer through the methodical platform based on traditional medicinal knowledge

  • Jungwhoi Lee;Jungsul Lee;WooGwang Sim;Jae-Hoon Kim;Chulhee Choi;Jongwook Jeon
    • BMB Reports
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    • v.56 no.11
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    • pp.594-599
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    • 2023
  • A number of therapeutic drugs have been developed from functional chemicals found in plants. Knowledge of plants used for medicinal purposes has historically been transmitted by word of mouth or through literature. The aim of the present study is to provide a systemic platform for the development of lead compounds against breast cancer based on a traditional medical text. To verify our systematic approach, integrating processes consisted of text mining of traditional medical texts, 3-D virtual docking screening, and in vitro and in vivo experimental validations were demonstrated. Our text analysis system identified rutin as a specific phytochemical traditionally used for cancer treatment. 3-D virtual screening predicted that rutin could block EGFR signaling. Thus, we validated significant anti-cancer effects of rutin against breast cancer cells through blockade of EGFR signaling pathway in vitro. We also demonstrated in vivo anti-cancer effects of rutin using the breast cancer recurrence in vivo models. In summary, our innovative approach might be proper for discovering new phytochemical lead compounds designing for blockade of malignant neoplasm including breast cancer.

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A Double Helix DNA Structure Based on the Block Circulant Matrix (I) (블록순환 행렬에 의한 이중나선 DNA 구조 (I))

  • Lee, Sung-Kook;Park, Ju-Yong;Lee, Moon-Ho
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.16 no.3
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    • pp.203-211
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    • 2016
  • The genetic code is a key to bio-informatics and to a science of biological self-organizing on the whole. Modern science faces the necessity of understanding and systematically explaining mysterious features of ensembles of molecular structures of the genetic code. This paper is devoted to symmetrical analysis for genetic systems. Mathematical theories of noise-immunity coding and discrete signal processing are based on Jacket matrix methods of representation and analysis of information. Both of the RNA and Jacket Matrix property also have the Element(Block) - wise Inverse Matrices. These matrix methods, which are connected closely with relations of symmetry, are borrowed for a matrix analysis of ensembles of molecular elements of the genetic code. This method is presented for its simplicity and the clarity with which it decomposes a Jacket Matrix in terms of the genetic RNA Codon.

Deep Learning-based Super Resolution Method Using Combination of Channel Attention and Spatial Attention (채널 강조와 공간 강조의 결합을 이용한 딥 러닝 기반의 초해상도 방법)

  • Lee, Dong-Woo;Lee, Sang-Hun;Han, Hyun Ho
    • Journal of the Korea Convergence Society
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    • v.11 no.12
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    • pp.15-22
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    • 2020
  • In this paper, we proposed a deep learning based super-resolution method that combines Channel Attention and Spatial Attention feature enhancement methods. It is important to restore high-frequency components, such as texture and features, that have large changes in surrounding pixels during super-resolution processing. We proposed a super-resolution method using feature enhancement that combines Channel Attention and Spatial Attention. The existing CNN (Convolutional Neural Network) based super-resolution method has difficulty in deep network learning and lacks emphasis on high frequency components, resulting in blurry contours and distortion. In order to solve the problem, we used an emphasis block that combines Channel Attention and Spatial Attention to which Skip Connection was applied, and a Residual Block. The emphasized feature map extracted by the method was extended through Sub-pixel Convolution to obtain the super resolution. As a result, about PSNR improved by 5%, SSIM improved by 3% compared with the conventional SRCNN, and by comparison with VDSR, about PSNR improved by 2% and SSIM improved by 1%.

Improvement in Exercise Endurance by Hovenia dulcis Fruit Hot Water Extract in Mice (헛개나무열매 열수추출물 투여에 의한 흰쥐의 지구력 향상 효과)

  • Kwon, Tae-Hyung;Han, Joon-Hee;Lee, Sun-Yeop;Yu, Keun-Hyung
    • The Korean Journal of Food And Nutrition
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    • v.33 no.4
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    • pp.363-371
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    • 2020
  • This study was designed to evaluate the improvement in exercise endurance by Hovenia dulcis fruit hot water extract (HDWE) for the potential application as a functional food material. The effect was based on the evaluation of the forced-swimming capacity and changes in biochemical parameters in mice. Six-week-old mice were classified into four groups based on a randomized block design: the negative control group, the HDWE 50 mg/kg body weight group, the HDWE 200 mg/kg body weight group, and the 1-octacosanol 50 mg/kg body weight group (n=8 mice per group). The swimming exercise time in the HDWE-50 group was increased at 545±43 sec compared to the control group at 263±28 sec. The HDWE-200 fatigue indicators, lactate acid and ammonia content, decreased to 4.99±0.33 mg/mL and 0.63±0.05 mg/mL, respectively. In addition, the content of glycogen in the liver and muscle tended to increase in the group administered HDWE but was not significant. Likewise, the LDH and glucose contents were increased compared to the control group. The muscle damage indicators ALT (52.7±2.6 U/L) and AST (42.5±5.2 U/L) tended to decrease compared to the control group (76.4±10.2 U/L).

Effects of far infrared radiological materials on immune response and changes of fecal microorganism in pigs (돼지에 있어 원적외선 방사물질의 첨가가 면역반응 및 분중 미생물의 변화에 미치는 영향)

  • Kwon, Ki-bum;Kim, In-ho;Hong, Jong-wook;Moon, Tea-hyun;Choi, Sang-yul;Seok, Ho-bong
    • Korean Journal of Veterinary Research
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    • v.41 no.1
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    • pp.37-42
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    • 2001
  • This research was conducted to investigate the effects of far infrared radiological materials on growth performance, immune response and changes of microbial flora in feces for growing pigs. Twelve growing pigs($Duroc{\times}Yorkshire{\times}Landrace$, average initial body weight of $15.6{\pm}0.5kg$) were used in a 40 day growth assay. Treatments were control(saline injection with diet: S); saline injection with Bio-Plus in diet(SBP); and vaccination with Bio-Plus in diet(VBP) in a randomized complete block design with initial BW as the blocking criterion. Serum concentrations of IgG of SBP and VBP were higher than those of S at day 10(p<0.05), 20(p<0.05), 30(p<0.05) and 40(p<0.05). Pigs fed with treatment diets had increased lymphocyte level compared to S at day 20(p<0.05) and 40(p<0.05). Cortisol was lower in treatments than in S at day 30(p<0.05). At day 20, there was no significant difference in E. coli among the treatments. However, it was observed that E, coli of the treatments was decreased compared to S at day 40(p<0.01). Lactobacillus of SBP was significantly higher(p<0.05) than that of S at day 40. In conclusion, the results of the experiment suggest that far infrared radiological materials could be a very beneficial immune response for growing pigs in health aspects.

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A Comparison of the Effects of Worker-Related Variables on Process Efficiency in a Manufacturing System Simulation

  • Lee, Dongjune;Park, Hyunjoon;Choi, Ahnryul;Mun, Joung H.
    • Journal of Biosystems Engineering
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    • v.38 no.1
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    • pp.33-40
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    • 2013
  • Purpose: The goal of this study was to build an accurate digital factory that evaluates the performance of a factory using computer simulation. To achieve this goal, we evaluated the effect of worker-related variables on production in a simulation model using comparative analysis of two cases. Methods: The overall work process and worker-related variables were determined and used to build a simulation model. Siemens PLM Software's Plant Simulation was used to build a simulation model. Also, two simulation models were built, where the only difference was the use of the worker-related variable, and the total daily production analyzed and compared in terms of the individual process. Additionally, worker efficiency was evaluated based on worker analysis. Results: When the daily production of the two models were compared, a 0.16% error rate was observed for the model where the worker-related variables were applied and error rate was approximately 5.35% for the model where the worker-related variables were not applied. In addition, the production in the individual processes showed lower error rate in the model that included the worker-related variables than the model where the worker-related variables were not used. Also, among the total of 22 workers, only three workers satisfied the IFRS (International Financial Reporting Standards) suggested worker capacity rate (90%). Conclusions: In the daily total production and individual process production, the model that included the worker-related variables produced results that were closer to the real production values. This result indicates the importance of worker elements as input variables, in regards to building accurate simulation models. Also, as suggested in this study, the model that included the worker-related variables can be utilized to analyze in more detail actual production. The results from this study are expected to be utilized to improve the work process and worker efficiency.

Selection of Lentinula edodes Sawdust Cultivation Cultivars Suitable for Sawdust Block Medium Cultivation (사각블럭배지 재배에 적합한 표고 톱밥재배 품종 선발)

  • Min-Jun Kim;Yeun Sug Jeong;Eunjin Kim;Yeongseon Jang;Kang-Hyeon Ka
    • The Korean Journal of Mycology
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    • v.51 no.2
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    • pp.81-90
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    • 2023
  • The cultivation method of shiitake is divided into two methods: log cultivation and sawdust cultivation. Recently, the importance of sawdust cultivation has been highlighted due to problems such as environmental problems, rising labor costs, and a reduced labor force. Among the 24 Sawdust-cultivated Lentinula edodes cultivars in Korea stored by the National Institute of Forest Science, this study was conducted to select excellent cultivars under the sawdust block cultivation method. After inoculation, the sawdust mediums were cultured for 100 days (60 days in dark and then 40 days in light), and only Sanjo 712ho sprouted the primordia on the 10th day of light culture (total 70 days of cultivation). As a result of cultivation, the average total yield of the 24 cultivars were 1,816 g and Sanjo 712ho was 2,267 g. The fruiting body yield was the highest in Sanjo 713ho with 3,443 g followed by Sanjo 710ho (3,355 g). Sanlim 10ho, Sansanhyang, and Sanjo 716ho showed low production with 174, 238, and 214 g, respectively. As a result of investigating the morphological characteristics of the fruit bodies, the fresh weight of Sansanhyang and Bambithyang was about twice as heavy as the overall average, and Sulbaekhyang was about twice as light. Bambithyang was the largest and longest in diameter and length of the stipe, and the thickness of the stem was the thickest in Sanjo 716ho. As for the hardness of pileus, Bambithyang showed the highest value at 1,276 g/5 mm, and Sanjo 711ho showed the lowest value at 542 g/5 mm. In summary, Bambithyang showed the best fruiting body characteristics and Sanjo 713ho showed the highest yield in the sawdust block cultivation method. This study, the cultivar with shortened cultivation periods and cultivars with excellent morphological characteristics and high yields.