• Title/Summary/Keyword: Bio-Sensor

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Preparation of the Citrobacter freundii Bio-Sensor for the Determination of Glucose and Its Applications (Glucose 정량을 위한 Citrobacter freundii Bio-Sensor의 개발과 그 응용)

  • Ihn Gwon-Shik;Hong Young-Seuk;Kim Ui-Rak;Jang Seh-Yong;Sohn Moo-Jeong
    • Journal of the Korean Chemical Society
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    • v.34 no.5
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    • pp.424-429
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    • 1990
  • A bio-sensor for the determination of glucose has been constructed by immobilizing the Citrobacter freundii or its organelle on carbon dioxide gas-sensor. The bacterial sensor was better than organelle in response, but the latter showed a shorter response time. The bacterial sensor gave linearity between 7.0 ${\times}\;10^{-4}$ and 1.0 ${\times}\;10^{-2}$ M glucose with a slope of 42.2 mV/decade in pH 7.0, 0.2 M tris-HCl buffer at 30$^{\circ}C$. The selectivity of this sensor was very high for glucose. Employing for the determination of glucose in serum, the sensor showed a good agreement with a routine analyzer.

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Electrochemical Biosensors for Biomedical and Clinical Applications: A Review

  • Rahman Md. Aminur;Park Deog-Su;Shim Yoon-Bo
    • Journal of Biomedical Engineering Research
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    • v.26 no.5
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    • pp.271-282
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    • 2005
  • There are strong demands for accurate, fast, and inexpensive devices in the medical diagnostic laboratories, such as biosensors and chemical sensors. Biosensors can provide the reliable and accurate informations on the desired biochemical parameters, which is an essential prerequisite for a patient before going for a treatment. They can be used for continuous measurements of metabolites, blood cations, gases, etc. Of these, electrochemical biosensors play an important role in the improvement of public health, because rapid detection, high sensitivity, small size, and specificity are achievable for clinical diagnostics. In this paper, the clinical applications with electrochemical biosensors are reviewed. An attempt is also made to highlight some of the trends that govern the research and developments of the important biosensors that are associated to clinical diagnosis.

Fabrication of Metallic Nano-filter Using UV-Imprinting Process (UV 임프린팅 공정을 이용한 금속막 필터제작)

  • Noh Cheol Yong;Lee Namseok;Lim Jiseok;Kim Seok-min;Kang Shinill
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2005.05a
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    • pp.237-240
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    • 2005
  • The demand of micro electrical mechanical system (MEMS) bio/chemical sensor is rapidly increasing. To prevent the contamination of sensing area, a filtration system is required in on-chip total analyzing MEMS bio/chemical sensor. A nano-filter was mainly applied in some application detecting submicron feature size bio/chemical products such as bacteria, fungi and so on. We suggested a simple nano-filter fabrication process based on replication process. The mother pattern was fabricated by holographic lithography and reactive ion etching process, and the replication process was carried out using polymer mold and UV-imprinting process. Finally the nano-filter is obtained after removing the replicated part of metal deposited replica. In this study, as a practical example of the suggested process, a nano-dot array was replicated to fabricate nano-filter fur bacteria sensor application.

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Development of Pressure Monitoring System Using Silicon Pressure Sensor (실리콘 압력센서를 이용한 압력 모니터링 시스템 개발)

  • Lee, Young Tae;Kwon, Ik Hyun
    • Journal of the Semiconductor & Display Technology
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    • v.17 no.4
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    • pp.76-79
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    • 2018
  • In this paper, we developed a pressure monitoring system using silicon pressure sensor. The pressure monitoring system was developed on the basis of a microcontroller, and a self-developed silicon pressure sensor was applied. The pressure monitoring system outputs the current pressure value via UART communication. In addition, it includes a function of displaying by LED when the preset three-step pressure (low, medium, high pressure) is reached. The silicon pressure sensor used in the pressure monitoring system was set to 0 kPa, 10 kPa, 26 kPa, and the pressure monitoring system was evaluated because the measured maximum pressure was in the range of 100 kPa.

Design of Implantable Wireless Sensor Node to Monitor the Livestock Body Temperature (가축의 실시간 체온 측정을 위한 이식형 무선 센서 노드 설계)

  • Kim, Hyun-Joong;Yang, Hyun-Ho
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2009.10a
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    • pp.585-588
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    • 2009
  • Wireless Sensor Network (WSN) is consisted of lots of tiny sensor nodes with limited processing power and computing resources. Thus, the most critical and fundamental element of WSN technology is sensor node, which gathers environmental information and transmits it to the user application systems. Due to the technological advancement, sensor nodes are become smaller and more intelligent, hence, expand their application area. Specifically, implantable wireless sensor node technology, to monitor and treat disease by implanting tiny sensor nodes into human body or livestock, shows further directions of WSN. In this paper, we have designed an implantable wireless sensor node to monitor livestock body temperature in real time. We also discussed on the additional considerations to implement real time bio-monitoring systems.

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X-ray grayscale lithography for sub-micron lines with cross sectional hemisphere for Bio-MEMS application (엑스선 그레이 스케일 리소그래피를 활용한 반원형 단면의 서브 마이크로 선 패턴의 바이오멤스 플랫폼 응용)

  • Kim, Kanghyun;Kim, Jong Hyun;Nam, Hyoryung;Kim, Suhyeon;Lim, Geunbae
    • Journal of Sensor Science and Technology
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    • v.30 no.3
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    • pp.170-174
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    • 2021
  • As the rising attention to the medical and healthcare issue, Bio-MEMS (Micro electro mechanical systems) platform such as bio sensor, cell culture system, and microfluidics device has been studied extensively. Bio-MEMS platform mostly has high resolution structure made by biocompatible material such as polydimethylsiloxane (PDMS). In addition, three dimension structure has been applied to the bio-MEMS. Lithography can be used to fabricate complex structure by multiple process, however, non-rectangular cross section can be implemented by introducing optical apparatus to lithography technic. X-ray lithography can be used even for sub-micron scale. Here in, we demonstrated lines with round shape cross section using the tilted gold absorber which was deposited on the oblique structure as the X-ray mask. This structure was used as a mold for PDMS. Molded PDMS was applied to the cell culture platform. Moreover, molded PDMS was bonded to flat PDMS to utilize to the sub-micro channel. This work has potential to the large area bio-MEMS.

Diffraction Characteristics for Optical Bio-Sensor of Bi-level Grating with Mushroom Profile (버섯형 이중 격자구조의 광 바이오센서에 대한 회절 특성)

  • Ho, Kwang-Chun
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.22 no.2
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    • pp.129-134
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    • 2022
  • The resonant bio-sensor of bi-level grating structure with mushroom profile has been designed for operating in the near-infrared (NIR) wavelength range under transverse electric (TE) polarization. The rigorous modal transmission-line theory (MTLT) is applied to determine the optical characteristics, and the reflection resonance of the grating structure is analyzed by varying their geometrical parameters. The numerical result shows that an excited sharp Fano resonance (FR), which does not occur in single layer grating, is demonstrated. The relationship between structure parameters of bi-level grating and the reflectance spectrum in order to guarantee the appearance of FR in the designed structure is fully investigated. An optical bio-sensor with a potential sensitivity of 112.9~214.3 deg/RIU and 447 nm/RIU is designed based on the proposed structure. The proposed mushroom profile may serve as a powerful sample for the design of optical bio-sensors with a wide range of applications.

A Wireless Intraocular Pressure Sensor with Variable Inductance Using a Ferrite Material

  • Kang, Byungjoo;Hwang, Hoyong;Lee, Soo Hyun;Kang, Ji Yoon;Park, Joung-Hu;Seo, Chulhun;Park, Changkun
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.13 no.4
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    • pp.355-360
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    • 2013
  • A wireless intraocular (IOP) pressure sensor based on micro electro mechanical system (MEMS) technology is proposed. The proposed IOP sensor uses variable inductance according to the external pressure. The proposed sensor is composed of two flexible membranes: a ferrite bottom part, an inductor, and a capacitor. The inductance of the sensor varies according to the external pressure. The resonance frequency of the sensor is also varied, and this frequency is detected using an external coil. The external coil is designed with an FR-4 printed circuit board. The feasibility of the proposed sensor structure using variable inductance to detect the external pressure is successfully demonstrated.

Biologically Inspired Node Scheduling Control for Wireless Sensor Networks

  • Byun, Heejung;Son, Sugook;Yang, Soomi
    • Journal of Communications and Networks
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    • v.17 no.5
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    • pp.506-516
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    • 2015
  • Wireless sensor networks (WSNs) are generally comprised of densely deployed sensor nodes, which results in highly redundant sensor data transmissions and energy waste. Since the sensor nodes depend on batteries for energy, previous studies have focused on designing energy-efficient medium access control (MAC) protocols to extend the network lifetime. However, the energy-efficient protocols induce an extra end-to-end delay, and therefore recent increase in focus on WSNs has led to timely and reliable communication protocols for mission-critical applications. In this paper, we propose an energy efficient and delay guaranteeing node scheduling scheme inspired by biological systems, which have gained considerable attention as a computing and problem solving technique.With the identification of analogies between cellular signaling systems and WSN systems, we formulate a new mathematical model that considers the networking challenges of WSNs. The proposed bio-inspired algorithm determines the state of the sensor node, as required by each application and as determined by the local environmental conditions and the states of the adjacent nodes. A control analysis shows that the proposed bio-inspired scheme guarantees the system stability by controlling the parameters of each node. Simulation results also indicate that the proposed scheme provides significant energy savings, as well as reliable delay guarantees by controlling the states of the sensor nodes.

Determination of Glutamine Utilizing New Plant Tissue Bio-Sensor (새로운 식물조직 바이오센서에 의한 글루타민의 정량)

  • Ihn, Gwon Shik;Kim, Bong Won;Jeon, Yeong Guk
    • Journal of the Korean Chemical Society
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    • v.34 no.6
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    • pp.622-628
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    • 1990
  • The bio-sensor for glutamine has been constructed by immobilizing petal of the rose structural elements on an ammonia gas sensor. This sensor was investigated for the effects of pH, temperature, buffer solution, tissular amounts, interferences and lifetime. As a result, the tissue sensor showed linear range of $8.0 {\times} 10^{-4}$$5.0 {\times} 10^{-2}$ M glutamine with a slope of 52 mV/decade in pH 7.8, 0.2M phosphate beffer solution at 37$^{\circ}C$. The tissular amounts used for this sensor was 50 mg. This sensorr showed excellent selectivity. This sensor was compared with other structural elements of rose. Actually, this tissue sensor appeared to be very useful for the determination of glutamine.

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