• Title/Summary/Keyword: Bio-Function

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A Study on Purification Process of Sialic Acid from Edible Bird's Nest Using Affinity Bead Technology (식용 제비집으로부터 비극성 비드기술을 활용한 시알산의 분리정제방법에 관한 연구)

  • Kim, Dong-Myong;Jung, Ju-Yeong;Lee, Hyung-Kon;Kwon, Yong-Sung;Baek, Jin-Hong;Han, In-Suk
    • Journal of Marine Bioscience and Biotechnology
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    • v.12 no.2
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    • pp.81-90
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    • 2020
  • Sialic acid, which is contained in about 60-160 mg/kg in the edible bird's nest (EBN), is known to facilitate in the proper formation of synapses and improve memory function. The objective of this study is to extract effectively the sialic acid from edible bird's nest using affinity bead technology (ABT). After preparing the non-polar polymeric bead "KJM-278-28A" having a porous network structure, and then desorbed sialic acid was concentrated and dried. The analysis of the physicochemical properties of bead "KJM-278-28A" showed that the particle size was 400-700 ㎛, the moisture holding capacity was 67-70%, the surface area (BET) was 705-900 ㎡/g, and the average pore diameter 70-87 Å. The adsorption capacity of the bead "KJM-278-28A" for sialic acid was shown a strong physical force to bind sialic acid to the bead surface of 400 mg/L. In addition, as a result of analyzing the adsorption and desorption effects of sialic acid on water, ethanol, and 10% ethanol on the bead, it was confirmed that desorption effectively occurs from the beads when only ethanol is used. As a result of HPLC measurement of the separated sialic acid solution, a total of four sialic acid peaks of N-acetyl-neuraminic acid (Neu5Ac), α,β-anomer of Neu5Ac and N-glycoly-neuraminic acid were identified. Through these results, it was confirmed that it is possible to separate sialic acid from EBN extract with efficient and high yield when using ABT.

A Study on Particulate Matter Reduction Effects of Vegetation Bio-Filters by Airflow Volume (공조풍량별 식생바이오필터의 입자상 오염물질 저감효과 연구)

  • Choi, Boo Hun;Kim, Tae Han
    • Journal of the Semiconductor & Display Technology
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    • v.20 no.4
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    • pp.89-95
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    • 2021
  • As the influence of fine dust on society spreads gradually, the public's interest in indoor air is increasingly rising. Air-purifying plants are drawing keen attention due to their natural purifying function enabled by plant physiology. However, as their fine dust reduction mechanism is limited to adsorption only, vegetation bio-filters that optimize purification effects through integration with air-conditioning systems is rising as an alternative. In accordance with the relevant standard test methods, this study looked into the fine dust reduction assessment method by air-conditioning airflow volume that can be used for the industrial spread of vegetation bio-filters. In the case of PM10 at 300 ㎍/m3, it was in the order of EG-B(3,500CMH, 29 min.) < EG-A (2,500CMH, 37 min.) < CG(0CMH, 64 min.) for reaching the maintenance level (100 ㎍/m3) of publicly used facilities. For reaching the WHO Guideline(50 ㎍/m3) requirement, it was in the order of EG-B (51 min.) < EG-A (160 min.) < CG (170 min.). In the case of PM2.5, it was in the order of EG-B (26 min.) < EG-A (33 min.) < CG (57 min.) for reaching the maintenance level (50 ㎍/m3) of publicly used facilities. It was in the order of EG-B (48 min) < EG-A (140 min) < CG (158 min) for reaching the WHO Guideline (25 ㎍/m3) requirement. The findings from the analysis showed that fine dust can be reduced most efficiently when the system is operated at 3,500CMH level. The limitation of this study is that due to the absence of a way of assessing the stress of plants in vegetation bio-filters, generating optimal air-conditioning air flow of the relevant system and economics analysis against the existing facility-type air purification system have been clarified, which should be explored further though follow-up studies.

Study on maintaining healthy body and changes of human body by circadian rhythm (인체(人體)의 일주리듬에 따른 변화(變化)와 건강법(健康法)에 관한 연구(硏究))

  • Jeong, Sang Jee;Kang, Jung Soo
    • Journal of Haehwa Medicine
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    • v.12 no.1
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    • pp.103-121
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    • 2003
  • Human being can't live without nature, then the changes of nature affect human body. It means that human body has corresponding changes to the KI(vital energy) of nature. There is a stream of changes in human body which circulate mysteriously and punctually by the laws of nature. If this stream of changes fits into human's life style, it would be most effective. It has a certain mode continuously. So if a person has a habit fitting into it, he will get the healthiest body. Then the researcher tries to explain the changes in human body by the time, mainly focused on within 24 hours. it is showing not only the oriental view, but also the western's. The researcher can find the coincidence as followings. At In-Si(3-5 am), the body function and the body temperature get to the bottom, therefore it's good for him to wake up and to run the vital energy. At Sa-Si(9-11 am), the patience on pain anxiety and the psychic concentration get to the top, he'd better start the work. At O-Si(11am-1pm), the heart energy has a vital move, then the blood concentration of Hb(hemoglobin) gets to the top. At Mi-Si(1-3 pm), the muscle strength, the squeeze, and the breathing rate increase. The reflex nerve sensitivity gets to the top. Creativity, observation, and working efficiency go high, so it's time to work hard. At Hae-Si(9pm-1am), the body function falls, sleeping is needed. At Chuck-Si(1-3 am), the cell spontaneity gets to the top, immune lymphocyte moves actively, and the blood concentration of growth hormone gets to the top. These are liver's work. In west, there has been active studies on how to reduce the side effect by using a person's bio-rhythm based on the 'time treatment', and how to reorganize the bio-rhythm by using the machine and the age resistance based on the 'bio-watch'. Though the 'time treatment' means something, the artificial resistance on bio-rhythm seems to give bad effects to human body. If a person lives by regimen of oriental medicine, he will maintain the healthiest body. Regimen is that human body follows the laws of nature, and moves its mysterious, Punctual and periodical changes.

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Selection of (Ac/Ds) insertion mutant lines by abiotic stress and analysis of gene expression pattern of rice (Oryza sativar L.) (비생물학적 스트레스 관련 벼 Ac/Ds 삽입 변이체의 선발 및 유전자 발현 분석)

  • Jung, Yu-Jin;Park, Seul-Ah;Ahn, Byung-Ohg;Yun, Doh-Won;Ji, Hyeon-So;Lee, Gang-Sup;Park, Young-Whan;Suh, Seok-Cheol;Baek, Hyung-Jin;Lee, Myung-Chul
    • Journal of Plant Biotechnology
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    • v.35 no.4
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    • pp.307-316
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    • 2008
  • Transposon-mediated insertional mutagenesis is one of powerful strategy for assessing functions of genes in higher plants. In this report, we have selected highly susceptible and tolerance plant by screening about high salt (3% NaCl) and cold stresses ($4^{\circ}C$) from F2 seeds of 30,000 Ac/Ds insertional mutagenesis lines in rice (Oryza sativa L. cv. Dongjin). In order to identify the gene tagging, insertion of Ds element was analyzed by Southern blot and these results revealed that 19 lines were matched genotype of selected lines with phenotype from the first selected 212 lines, and 13 lines have one copy of Ds elements. The Franking Sequence Tags (FSTs) of selected mutant lines showed high similarities with the following known function genes: signal transduction and regulation of gene expression (transpoter, protease family protein and apical meristem family protein), osmotic stress response (heat shock protein, O-methyltransferase, glyceraldehyde-3-phosphate dehydrogenase and drought stress induce protein), vesicle trafficking (SYP 5 family protein) and senescence associated protein. The expression pattern of 19 genes were analyzed using RT-PCR under the abiotic stresses of 9 class; 250mM NaCl, osmotic, drought, 3% $H_2O_2$, $100{\mu}M$ ABA, $100{\mu}M$ IAA, 0.1 ppm 2,4-D, $4^{\circ}C$ cold and $38^{\circ}C$ high temperature. Isolated knock-out genes showed the positive response about 250 mM NaCl, drought, $H_2O_2$, PEG, IAA, 2,4-D, ABA treatment and low ($4^{\circ}C$) and high temperature ($38^{\circ}C$). The results from this study indicate that function of selected knock-out genes could be useful in improving of tolerance to abiotic stresses as an important transcriptional activators in rice.

Isolation of Sangivamycin from Streptomyces sp. A6497 and its Herbicidal Activity

  • HWANG EUI IL;YUN BONG SIK;CHOI SUNG WON;KIM JIN SEOG;LIM SE JIN;MOON JAE SUN;LEE SANG HAN;KIM SUNG UK
    • Journal of Microbiology and Biotechnology
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    • v.15 no.2
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    • pp.434-437
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    • 2005
  • During the screening for the inhibitors of cellulose biosynthesis as herbicides, we discovered a Streptomyces sp. A6497 with a selective antifungal activity against cellulose containing Phytophthora parasitica, but not against cellulose lacking Candida albicans. The inhibitor was isolated and identified, using a series of chromatographies. Based on structure analyses with UV spectrophotometry, mass and various NMR, the inhibitor was identified as sangivamycin. The compound exhibited strong antifungal activities against P. parasitica (MIC; 3.125 $\mu$g/ml). In particular, it showed strong herbicidal activities against various weeds in the greenhouse experiment. Taken together, these results suggest that sangivamycin is a useful lead compound for the development of new herbicides.

An recovery algorithm and error position detection in digital circuit mimicking by self-repair on Cell (세포의 자가 치료 기능을 모사한 디지털 회로에서의 오류위치 확인 및 복구 알고리즘)

  • Kim, Seok-Hwan;Hur, Chang-Wu
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2015.10a
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    • pp.842-846
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    • 2015
  • In this study, we propose an algorithm of the method of recovering quickly find the location of the error encountered during separate operations in the functional structure of complex digital circuits by mimicking the self-healing function of the cell. By the digital circuit was divided by 9 function block unit of function, proposes a method that It can quickly detect and recover the error position. It was the detection and recovery algorithms for the error location in the digital circuit of a complicated structure and could extended the number of function block for the $3{\times}3$ matrix structure on the digital circuit.

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An Error Detection and Recovery Algorithm in Digital Circuit Mimicking by Self-Repair on Cell (세포의 자가 치료 기능을 모사한 디지털 회로에서의 오류 검출 및 복구 알고리즘)

  • Kim, Soke-Hwan
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.19 no.11
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    • pp.2745-2750
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    • 2015
  • Abstract should be placed here In this study, we propose an algorithm of the method of recovering quickly find the location of the error encountered during separate operations in the functional structure of complex digital circuits by mimicking the self-healing function of the cell. By the digital circuit was divided by 9 function block unit of function, proposes a method that It can quickly detect and recover the error position. It was the detection and recovery algorithms for the error location in the digital circuit of a complicated structure and could extended the number of function block for the $3{\times}3$ matrix structure on the dital circuit.

The Effect of Horticultural Therapy on Cognitive Function, Depression, Self-esteem and Activity Daily Living(ADL) in Dementia Care - A Systematic Review and Meta-Analysis - (치매환자의 인지기능, 우울, 자아존중감, 일상생활수행능력에 미치는 원예치유 효과 - 체계적 문헌고찰 및 메타분석 -)

  • Bae, Seung-Jong;Lee, Sun-Hee;Kim, Dae-Sik
    • Journal of Korean Society of Rural Planning
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    • v.27 no.4
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    • pp.97-107
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    • 2021
  • The purpose of this study is to systematically review and to objectively identify the effect size in order to understand the effects of horticultural therapy on cognitive function, depression, self-esteem, and activity daily living(ADL) of dementia patients. Related studies published in Korean and English were selected by searching domestic and foreign academic databases. The risk of bias assessment of individual studies was performed on the included 18 literatures. Horticultural therapy was found to be significantly effective in cognitive function(effect size=1.06), depression(effect size=0.64), self-esteem(effect size=0.99), and ADL(effect size=1.98) in dementia care. It is expected that related experimental studies will be repeatedly conducted to produce a more objective effect size calculation.

PARAMETER IDENTIFICATION FOR NONLINEAR VISCOELASTIC ROD USING MINIMAL DATA

  • Kim, Shi-Nuk
    • Journal of applied mathematics & informatics
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    • v.23 no.1_2
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    • pp.461-470
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    • 2007
  • Parameter identification is studied in viscoelastic rods by solving an inverse problem numerically. The material properties of the rod, which appear in the constitutive relations, are recovered by optimizing an objective function constructed from reference strain data. The resulting inverse algorithm consists of an optimization algorithm coupled with a corresponding direct algorithm that computes the strain fields given a set of material properties. Numerical results are presented for two model inverse problems; (i)the effect of noise in the reference strain fields (ii) the effect of minimal reference data in space and/or time data.