• Physical Therapy Rehabilitation Science
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• 제6권4호
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• pp.176-181
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• 2017

Objective: The timed up and go (TUG) test is method used to determine the functional mobility of persons with stroke. Its reliability, validity, reaction rate, fall prediction, and psychological characteristics concerning ambulation ability have been validated. However, the relationship between TUG performance and community ambulation ability is unclear. The purpose of this study was to investigate whether the TUG performance time could indicate community ambulation levels (CAL) differentially in persons with chronic stroke. Design: Cross-sectional study. Methods: Eighty-seven stroke patients had participated in this study. Based on the self-reporting survey results on the difficulties experienced when walking outdoors, the subjects were divided into the independent community ambulation (ICA) group (n=35) and the dependent community ambulation group (n=52). Based on the area under the curve (AUC), the discrimination validity of the TUG performance time was calculated for classifying CAL. The Binomial Logistic Regression Model was utilized to produce the likelihood ratio of selected TUG cut-off values for the distinguishing of community ambulation ability. Results: The selected TUG cut-off values and the area under the curve were <14.87 seconds (AUC=0.871, 95% confidence interval=0.797-0.945), representing a mid-level accuracy. Concerning the likelihood ratio of the selected TUG cut-off value, it was found that the group with TUG performance times shorter than 14.87 seconds showed a 2.889 times higher probability of ICA than those with a TUG score of 14.87 seconds or longer (p<0.05). Conclusions: The TUG can be viewed as an assessment tool that is capable of classifying CAL.

• Journal of the Korean Statistical Society
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• 제32권2호
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• pp.121-150
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• 2003

The National Health Interview Survey (NHIS) is one of the surveys used to assess the health status of the US population. One indicator of the nation's health is the total number of doctor visits made by the household members in the past year, There is a substantial nonresponse among the sampled households, and the main issue we address here is that the nonrespones mechanism should not be ignored because respondents and nonrespondents differ. It is standard practice to summarize the number of doctor visits by the binary variable of no doctor visit versus at least one doctor visit by a household for each of the fifty states and the District of Columbia. We consider a nonignorable nonresponse model that expresses uncertainty about ignorability through the ratio of odds of a household doctor visit among respondents to the odds of doctor visit among all households. This is a hierarchical model in which a nonignorable nonresponse model is centered on an ignorable nonresponse model. Another feature of this model is that it permits us to "borrow strength" across states as in small area estimation; this helps because some of the parameters are weakly identified. However, for simplicity we assume that the hyperparameters are fixed but unknown, and these hyperparameters are estimated by the EM algorithm; thereby making our method Bayes empirical Bayes. Our main result is that for some of the states the nonresponse mechanism can be considered non-ignorable, and that 95% credible intervals of the probability of a household doctor visit and the probability that a household responds shed important light on the NHIS.

• Asian Pacific Journal of Cancer Prevention
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• 제15권22호
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• pp.9859-9863
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• 2014

Genetic epidemiological studies have shown that genetic susceptibility to esophageal cancer (EC) is an important cause of its high incidence within families in some areas of China. The purpose of this study was to obtain evidence of a genetic basis of EC in Xin-an and Xin-xiang counties in China. Familial aggregation and complex segregation analyses were performed of 79 EC families in these counties. The heritability of EC was examined using Falconer's method and complex segregation analysis was conducted with the SEGREG program in Statistical Analysis for Genetic Epidemiology (SAGE version 5.3.1). The results showed that the distribution of EC in families did not fit well into a binomial distribution. The heritability of EC among first-degree and second-degree relatives was $67.0{\pm}7.31%$ and $43.1%{\pm}9.80%$, respectively, and the summing up powered heritability was $53.2{\pm}6.74%$. The segregation ratio was 0.045. Complex segregation analysis showed that the genetic model of EC was additive. The current results provide evidence for an inherited propensity to EC in certain high-risk groups in China, and support efforts to identify the genes that confer susceptibility to this disease.

• 응용통계연구
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• 제19권1호
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• pp.171-181
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• 2006

모비율 차이의 구간 추정에서 표준으로 인식되고 있는 Wald 신뢰구간은 모비율 구간 추정과 마찬가지로 포함확률의 근사성에서 문제가 있다는 것이 알려져 있다. 이에 대한 대안으로 모비율 차이의 신뢰구간에 대한 많은 연구가 있어 왔으나 대부분의 신뢰구간은 매우 복잡한 과정을 통해 얻어지게 되어 있어 실용성에 대한 문제가 제기될 수 있다. 이와 비교하여 Agresti와 Caffo(2000)에 의해 제시된 신뢰구간은 매우 간편한 식에 의해 구할 수 있어 이해하기 쉽고 포함확률과 포함확률의 평균절대오차에 있어 다른 복잡한 신뢰 구간과 필적할 수 있다. 그러나 Agresti-Caffo 신뢰 구간은 포함확률이 명목 신뢰수준을 상회하는 보수적인 구간으로 알려져 있다. 본 논문에서는 이승천(2005)에서 이항비율의 신뢰구간을 구하기 위해 사용된 가중 Polya 사후분포를 이용하여 두 모비율 차이의 신뢰구간을 구하였다. 이렇게 구하여진 신뢰구간은 간편성은 물론 Agresti-Caffo 신뢰구간의 보수성을 개선하였다.

• 대한간호학회지
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• 제50권5호
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• pp.658-670
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• 2020

Purpose: This study aimed to identify the predictors of blood and body fluid exposure (BBFE) in multifaceted individual (sleep disturbance and fatigue), occupational (occupational stress), and organizational (hospital safety climate) factors, as well as infection prevention behavior. We also aimed to test the mediating effect of infection prevention behavior in relation to multifaceted factors and the frequency of BBFE. Methods: This study was based on a secondary data analysis, using data of 246 nurses from the Shift Work Nurses' Health and Turnover study. Based on the characteristics of zero-inflated and over-dispersed count data of frequencies of BBFE, the data were analyzed to calculate zero-inflated negative binomial regression within a generalized linear model and to test the mediating effect using SPSS 25.0, Stata 14.1, and PROCESS macro. Results: We found that the frequency of BBFE increased in subjects with disturbed sleep (IRR = 1.87, p = .049), and the probability of non-BBFE increased in subjects showing higher infection prevention behavior (IRR = 15.05, p = .006) and a hospital safety climate (IRR = 28.46, p = .018). We also found that infection prevention behavior had mediating effects on the occupational stress-BBFE and hospital safety climate-BBFE relationships. Conclusion: Sleep disturbance is an important risk factor related to frequency of BBFE, whereas preventive factors are infection prevention behavior and hospital safety climate. We suggest individual and systemic efforts to improve sleep, occupational stress, and hospital safety climate to prevent BBFE occurrence.

• Journal of the Korean Data and Information Science Society
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• 제21권3호
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• pp.407-417
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• 2010

신BIS협약에서는 자본적정성 규제에 있어서 자율성 확대를 위해 내부등급시스템을 허용하였고, 이에 따라 시스템의 적합성 검증의 중요성을 더욱 강조하게 되었다. 적합성검증은 양적 질적 검증으로 나뉘며 이 때 양적 검증은 변별력, 안정성, 등급의 계량화로 구별된다. 본 논문에서는 양적 검증의 등급의 계량화 중 신용등급 변화 검정기법에 대하여 연구하려고 한다. 등급의 계량화 검정은 등급별로 추정된 부도율과 실제 부도율과의 차이를 검정하는 방법으로 한 시점에 대한 검정으로 이항검정과 카이제곱검정, Brier score, 신호등 검정이 있고, 여러 시점의 정확성을 검증하는 방법으로 정규성 검정, 확장된 신호등 검정이 있다. 신용평가시스템의 정확성을 높이고, 현실 상황에 반영이 가능하려면 상관관계를 고려하지 않을 수 없다. 본 논문에서는 부도상관관계를 고려한 확장된 신호등 검정을 제안하고자 한다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6797-6802
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• 2013

Background: Prevalence of tobacco use is higher in the rural than urban areas of India. Unlike tobacco cessation clinics located in urban areas, community-based smoking cessation intervention has the potential to reach a wider section of the community to assist in smoking cessation in the rural setting. The present study aimed to assess the effectiveness of a cessation intervention in rural Kerala state, India. Materials and Methods: Current daily smoking resident males in the age group 18-60 years from four community development blocks in rural Kerala were randomly allocated to intervention and control groups. The intervention group received multiple approaches in which priority was given to face-to-face interviews and telephone counselling. Initially educational materials on tobacco hazards were distributed. Further, four rounds of counselling sessions were conducted which included a group counselling with a medical camp as well as individual counselling by trained medical social workers. The control group received general awareness training on tobacco hazards along with an anti-tobacco leaflet. Self-reported smoking status was assessed after 6 and 12 months. Factors associated with tobacco cessation were estimated using binomial regression method. Results: Overall prevalence of smoking abstinence was 14.7% in the intervention and 6.8% in the control group (Relative risk: 1.85, 95% CI: 1.05, 3.25). A total of 41.3% subjects in the intervention area and 13.6% in the control area had reduced smoking by 50% or more at the end of 12 months. Lower number of cigarettes/ bidi used, low nicotine dependence and consultation with a doctor for a medical ailment were the statistically significant predictors for smoking cessation. Conclusions: Rigorous approaches for smoking cessation programmes can enhance quit rates in smoking in rural areas of India.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.2179-2184
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• 2012

Introduction and aim: To compare reproductive factor influence on patients with pathological diagnosed malignant and benign tumor in the Breast Department, The First Peoples' Hospital of Kunming in Yunnan province, China. Methods: A hospital-based case-control study was conducted on 263 breast cancer (BC) cases and 457 non-breast cancer controls from 2009 to 2011. The cases and controls information on demographics, medical history, and reproductive characteristics variables were collected using a self-administered questionnaire and routine medical records. Histology of breast cancer tissue and benign breast lesion were documented by pathology reports. Since some variables in data analysis had zero count in at least one category, binomial-response GLM using the bias-reduction method was applied to estimate OR's and their 95% confidence intervals (95% CI). To adjust for age and menopause status, a compound variable comprising age and menopausal status was retained in the statistical models. Results: multivariate model analysis revealed significant independent positive associations of BC with short menstrual cycle, old age at first live birth, never breastfeeding, history of oral contraception experience, increased number of abortion, postmenopausal status, and nulliparity. Categorised by age and menopausal status, perimenopausal women had about 3-fold and postmenopausal women had more than 5-fold increased risk of BC compared to premenopausal women. Discussion and Conclusion: This study has confirmed the significant association of BC and estrogen related risk factors of breast cancer including longer menstrual cycle, older age of first live birth, never breastfeeding, nulliparity, and number of abortions more than one. The findings suggest that female hormonal factors, especially the trend of menopause status play a significant role in the development of BC in Yunnan women.

• 응용통계연구
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• 제20권1호
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• pp.183-194
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• 2007

이 논문에서는 두 독립인 이항 확률의 비교에서 이항 확률 중 하나 또는 모두가 0.05보다 작을 경우의 두 확률의 비교에 대한 표본수 계산의 문제를 다루었다. Whitte-more(1981)는 여러 공변량에 근거한 로지스틱 회귀를 이용하여 극소 확률의 경우에 대한 수정 표본수 공식을 제안하였다. 이를 독립된 비율의 비교에 적용하여 이로부터 계산한 표본수는 일반적으로 많이 사용하는 근사 정규 방법, 특히 극소 비율의 비교에 대한 방법이 아닌 근사 정규 방법의 표본수 보다도 훨씬 큰 표본수를 제시하고 있다. 그러므로, 응용분야의 통계인들은 극소 반응 확률에 근거한 임상 시험을 계획할 경우 계획의 단계에서 의도하는 검정력을 확보하기 위해 교과서에 제시된 표본수 공식이나 부표에 의존한다면 위험할 수 있음을 이 논문의 결과가 말해 주고 있다.

• 대한교통학회지
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• 제25권1호
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• pp.23-35
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• 2007

고속도로 분류부는 고속에서 저속으로의 급격한 감속, 양호한 기하구조에서 취약한 기하구조로의 급격한 선형변화가 발생하는 구간으로, 고속도로 구성요소 중 사고위험이 매우 높은 구간에 해당된다 따라서 분류부 설계시는 안전하고 원활한 교통흐름이 이루어지도록 세심한 주의를 기울여야 함은 물론 이의 달성을 위한 설계기준이 수립되어야 한다. 이에 따라 현 도로설계기준에서는 차로변경을 위한 변이구간, 감속을 위한 감속구간 그리고 무한 곡선반경에서 유한곡선반경으로의 원활한 차량주행궤적 변경을 위한 완화곡선 등 이를 위한 설계기준을 제시하고 있으나, 실제 그 적용에 있어서는 설계기준상의 각 구간별 구성에 대한 정의가 명확하지 않아 분류부의 각 구성요소가 중첩되어 설계되고 있다. 이러한 설계기준상의 문제로 인한 각 구성요소간 혼재는 현 설계기준에서 의도하고 있는 분류부에서의 역할을 충분히 발휘하지 못하게 하는 결과를 초래하고 있으며 일관된 선형을 기대하는 운전자에게 혼동을 야기시키는 등 많은 고속도로 분류부 현장에서 안전상 문제점으로 작용하고 있다. 따라서 본 연구에서는 고속도로 분류부에서의 실측 현장조사 데이터를 바탕으로 분류부 차량주행행태 특성 분석 및 사고예측모형의 개발을 통해 다양한 교통조건 및 기하구조 조건을 고려한 분류부 설계기준 개선안을 제시하였다.