• Journal of Gastric Cancer
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• 제16권2호
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• pp.63-71
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• 2016

Pylorus-preserving gastrectomy (PPG) is a function-preserving surgery for the treatment of early gastric cancer (EGC), aiming to decrease the complication rate and improve postoperative quality of life. According to the Japanese gastric cancer treatment guidelines, PPG can be performed for cT1N0M0 gastric cancer located in the middle-third of the stomach, at least 4.0 cm away from the pylorus. Although the length of the antral cuff gradually increased, from 1.5 cm during the initial use of the procedure to 3.0 cm currently, its optimal length still remains unclear. Standard procedures for the preservation of pyloric function, infra-pyloric vessels, and hepatic branch of the vagus nerve, make PPG technically more difficult and raise concerns about incomplete lymph node dissection. The short- and long-term oncological and survival outcomes of PPG were comparable to those for distal gastrectomy, but with several advantages such as a lower incidence of dumping syndrome, bile reflux, and gallstone formation, and improved nutritional status. Gastric stasis, a typical complication of PPG, can be effectively treated by balloon dilatation and stent insertion. Robot-assisted pylorus-preserving gastrectomy is feasible for EGC in the middle-third of the stomach in terms of the short-term clinical outcome. However, any benefits over laparoscopy-assisted PPG (LAPPG) from the patient's perspective have not yet been proven. An ongoing Korean multicenter randomized controlled trial (KLASS-04), which compares LAPPG and laparoscopy-assisted distal gastrectomy for EGC in the middle-third of the stomach, may provide more clear evidence about the advantages and oncologic safety of PPG.

• Journal of Gastric Cancer
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• 제19권4호
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• pp.438-450
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• 2019

Purpose: Although linear-shaped gastroduodenostomy (LSGD) was reported to be a feasible and reliable method of Billroth I anastomosis in patients undergoing totally laparoscopic distal gastrectomy (TLDG), the feasibility of LSGD for patients undergoing totally robotic distal gastrectomy (TRDG) has not been determined. This study compared the feasibility of LSGD in patients undergoing TRDG and TLDG. Materials and Methods: All c: onsecutive patients who underwent LSGD after distal gastrectomy for gastric cancer between January 2009 and December 2017 were analyzed retrospectively. Propensity score matching (PSM) analysis was performed to reduce the selection bias between TRDG and TLDG. Short-term outcomes, functional outcomes, learning curve, and risk factors for postoperative complications were analyzed. Results: This analysis included 414 patients, of whom 275 underwent laparoscopy and 139 underwent robotic surgery. PSM analysis showed that operation time was significantly longer (163.5 vs. 132.1 minutes, P<0.001) and postoperative hospital stay significantly shorter (6.2 vs. 7.5 days, P<0.003) in patients who underwent TRDG than in patients who underwent TLDG. Operation time was the independent risk factor for LSGD after intracorporeal gastroduodenostomy. Cumulative sum analysis showed no definitive turning point in the TRDG learning curve. Long-term endoscopic findings revealed similar results in the two groups, but bile reflux at 5 years showed significantly better improvement in the TLDG group than in the TRDG group (P=0.016). Conclusions: LSGD is feasible in TRDG, with short-term and long-term outcomes comparable to that in TLDG. LSGD may be a good option for intracorporeal Billroth I anastomosis in patients undergoing TRDG.

• Journal of Gastric Cancer
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• 제9권4호
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• pp.207-214
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• 2009

목적: 위체부에 발생하는 조기위암에 대해 원위부 위아전 절제술(SDG)이 표준 술식으로 시행되나 술 후 기능장애와 합병증이 있으며, 이런 단점을 최소화하기 위해 내시경적점막절제술을 하지만 림프절의 전이여부를 알 수 없는 단점이 있다. 위의 절제 범위를 줄이고 유문을 보존하고, 림프절의 절제가 가능한 위구획절제술(SG)에 대해 그 유용성을 평가하고자 한다. 대상 및 방법: 2004년 1월부터 2007년 7월까지 본원에서 위체부의 조기위암 환자 중 41명에서 SG를 하였고, 40명에서는 SDG를 하였다. 의무기록 및 전화를 이용한 설문을 이용하여 수술 후 6개월과 12개월의 영양상태와 술 후 합병증에 대해 두 군을 비교하였다. 결과: 영양상태의 변화(혈색소, 혈장단백, 혈장알부민, 혈장콜레스테롤, P>0.05)와 체중의 변화에서 유의한 차이는 보이지 않았다. SG군에서 SDG군에 비하여 내시경 시 잔여음식물(P<0.05)이 많았으나, 상복부 불편감이나 식사 시조기 팽만감에는 큰 차이가 없었다(P>0.05). 식도염은 두군에서 비슷한 발생률을 보였고(P>0.05), 담즙 역류는 SG군과 SDG군에서 각 한 명만 관찰이 되었다. 결론: SG군에서는 유문이 보존되므로 담즙 역류로 인한식도염, 위염의 발생 감소와, 위절제범위의 감소와 유문보존으로 인한 영양학적인 장점을 기대하였으나, 현재까지의 결과는 두 군에서 큰 차이를 발견할 수 없었다. SG의 장점과 단점을 알기 위해서는 더 오랜 기간의 경과관찰과 연구가 필요할 것으로 생각한다.